Initializations and how to have an influence on them?

[seb110393]

Hi,

I have some questions regarding your algorithm.

I would like to know how your algorithm does its initializations and if it's possible to have an influence on them?

Because to segment an mp2rage image, I use this command:

brain_seg -g -n 4 -C mprage.nii rmp2rage.nii -x mask.nii --em-iterations 3 --output-steps -o prefix2 -l 0.3

So "-g" means I'm using posteriori probability which is more robust than use an atlas. Am I right?

Do you have any recommendations in order to increase the quality of the results of segmentation in the case of an mp2rage?

Is it possible to find a paper that explains how the algorithm works?

Otherwise, I use this command:

brain_seg -g -n 4 -C mprage.nii --bias-ouput --bias-corrected-output -x mask.nii --em-iterations 3 --output-steps -o prefix2 -l 0.3

in order to get the estimated Bias field and the corrected input image. In this case (mprage), it works very well.

Thanks in advance.

seb