Evidence search

(under construction)

Inclusion criteria

Cohort studies that measures and provides a cross tabulation for the association between initial qSOFA score, SIRS score, Shock Index, lactate level, CRP level or other prognostic aid and mortality among patients with suspected infection.
Exclude cohorts of SIRS alone.

Reconciliation tables

Comparison of included studies with prior systematc reviews (Not applicable to this review as no prior review located.

PubMed

Boolean term searching

(sepsis OR infection) AND (SIRS OR qSOFA OR lactate OR procalcitonin OR index)

Retrieves all nine articles in hand (100% sensitivity)
55171 articles (sepsis OR infection) AND qSOFA
Retrieves all five articles in hand about qSOFA (100% sensitivity)
28 articles when limited to having abstracts (review pending)

Vector searching ('Related citations' search)

Seed articles (9): pending (search results reviewed 2/x/2017)

Cited reference searching

Identifying seminal studies that are the most highly cited at Google Scholar

Churpek MM, Snyder A, Han X, Sokol S, Pettit N, Howell MD, Edelson DP. qSOFA, SIRS, and Early Warning Scores for Detecting Clinical Deterioration in Infected Patients Outside the ICU. Am J Respir Crit Care Med. 2016 Sep 20. PMID: 27649072 - 10 citations

Searching within the highly citing studies using Google Scholar (7/17/2016)

Churpek MM, Snyder A, Han X, Sokol S, Pettit N, Howell MD, Edelson DP. qSOFA, SIRS, and Early Warning Scores for Detecting Clinical Deterioration in Infected Patients Outside the ICU. Am J Respir Crit Care Med. 2016 Sep 20. PMID: 27649072 - 10 citations (assessment pending)