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01_describe_cohorts.R
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01_describe_cohorts.R
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################################################################################
########## DESCRIBE COHORTS ##########
################################################################################
# Number of deaths by cohort and quarter
# Number of deaths by place - cohort and quarter
# Compare deaths by place, quarter and cause to inform cause of death groups
# Assess completeness of cohorts relative to deaths reported by ONS
# Number of deaths by cohort and characteristic with ratio comparison
# Summary table cohort characteristics
# Number of deaths by quarter and characteristics
# Summary table quarter characteristics
# Number of deaths by cohort, place of death and characteristics
# Summary table death characteristics by place and cohort
# Number of deaths by quarter, place of death and characteristics
# Summary table death characteristics by place and quarter
################################################################################
########## Libraries ##########
library("tidyverse")
library("lubridate")
################################################################################
########## Save locations ##########
fs::dir_create(here::here("output", "describe_cohorts"))
fs::dir_create(here::here("output", "describe_cohorts", "overall_death_counts"))
fs::dir_create(here::here("output", "describe_cohorts", "quarter_death_counts"))
fs::dir_create(here::here("output", "describe_cohorts", "ons_death_comparisons"))
fs::dir_create(here::here("output", "describe_cohorts", "death_ratios_cohort"))
fs::dir_create(here::here("output", "describe_cohorts", "death_ratios_pod_cohort"))
################################################################################
########## NT chart style ##########
# Nuffield Trust colour list
NT_colours <- c(
`NT ink` = "#271544",
`white` = "#FFFFFF",
`NT iris` = "#AC8ACF",
`cool black` = "#0E1B26",
`cool dark grey` = "#556370",
`cool mid grey` = "#9AA0AA",
`cool light grey` = "#F4F4F4",
`bright purple` = "#9F67FF",
`light purple 1` = "#D3C4FC",
`light purple 2` = "#B39DFF",
`dark purple 1` = "#7140EA",
`dark purple 2` = "#49148C",
`bright blue` = "#0066F4",
`light blue 1` = "#99DBFF",
`light blue 2` = "#63B2FF",
`dark blue 1` = "#005AC7",
`dark blue 2` = "#192889",
`bright red` = "#FF6B57",
`light red 1` = "#FFCFC9",
`light red 2` = "#FF997F",
`dark red 1` = "#B71C1C",
`dark red 2` = "#700C28",
`bright yellow` = "#EABE17",
`light yellow 1` = "#FDEA9D",
`light yellow 2` = "#F4D05A",
`dark yellow 1` = "#DD931C",
`dark yellow 2` = "#B26605",
`bright green` = "#00C27A",
`light green 1` = "#8BF8BD",
`light green 2` = "#39DA91",
`dark green 1` = "#00823F",
`dark green 2` = "#195442",
`bright cyan` = "#4DCFF5",
`light cyan 1` = "#9EF7FF",
`light cyan 2` = "#6AE8F9",
`dark cyan 1` = "#008CB3",
`dark cyan 2` = "#004C70"
)
NT_colour <- function(index = NULL, named = FALSE){
if(is.null(index)){
index <- names(NT_colours)
}
return_value <- NT_colours[index]
if (!named) {
names(return_value) <- NULL
}
return(return_value)
}
####################################
# NT colour palette
NT_palette <- function(NT_theme = NULL, reverse = FALSE, ...) {
function(n) {
stopifnot(n <= 5 | (n <= 12 & (is.null(NT_theme) | NT_theme == "bright")))
colour_indices <-
if (n == 1 & is.null(NT_theme)) { "bright purple" }
else if (n == 2 & is.null(NT_theme)) { c("bright purple", "bright green") }
else if (n == 3 & is.null(NT_theme)) { c("bright purple", "bright green", "bright blue") }
else if (n == 4 & is.null(NT_theme)) { c("bright purple", "bright green", "bright blue", "bright yellow") }
else if (n == 5 & is.null(NT_theme)) { c("bright purple", "bright green", "bright blue", "bright yellow", "bright red") }
else if (n == 6 & is.null(NT_theme)) { c("bright purple", "bright green", "bright blue", "bright yellow", "bright red", "bright cyan") }
else if (n == 7 & is.null(NT_theme)) { c("bright purple", "bright green", "bright blue", "bright yellow", "bright red", "bright cyan", "light purple 1") }
else if (n == 8 & is.null(NT_theme)) { c("bright purple", "bright green", "bright blue", "bright yellow", "bright red", "bright cyan", "light purple 1", "light green 1") }
else if (n == 9 & is.null(NT_theme)) { c("bright purple", "bright green", "bright blue", "bright yellow", "bright red", "bright cyan", "light purple 1", "light green 1", "light blue 1") }
else if (n == 10 & is.null(NT_theme)) { c("bright purple", "bright green", "bright blue", "bright yellow", "bright red", "bright cyan", "light purple 1", "light green 1", "light blue 1", "light yellow 1") }
else if (n == 11 & is.null(NT_theme)) { c("bright purple", "bright green", "bright blue", "bright yellow", "bright red", "bright cyan", "light purple 1", "light green 1", "light blue 1", "light yellow 1", "light red 1") }
else if (n == 12 & is.null(NT_theme)) { c("bright purple", "bright green", "bright blue", "bright yellow", "bright red", "bright cyan", "light purple 1", "light green 1", "light blue 1", "light yellow 1", "light red 1", "light cyan 1") }
else if (n == 1 & NT_theme == "bright") { "bright purple" }
else if (n == 2 & NT_theme == "bright") { c("bright purple", "bright green") }
else if (n == 3 & NT_theme == "bright") { c("bright purple", "bright green", "bright blue") }
else if (n == 4 & NT_theme == "bright") { c("bright purple", "bright green", "bright blue", "bright yellow") }
else if (n == 5 & NT_theme == "bright") { c("bright purple", "bright green", "bright blue", "bright yellow", "bright red") }
else if (n == 6 & NT_theme == "bright") { c("bright purple", "bright green", "bright blue", "bright yellow", "bright red", "bright cyan") }
else if (n == 7 & NT_theme == "bright") { c("bright purple", "bright green", "bright blue", "bright yellow", "bright red", "bright cyan", "light purple 1") }
else if (n == 8 & NT_theme == "bright") { c("bright purple", "bright green", "bright blue", "bright yellow", "bright red", "bright cyan", "light purple 1", "light green 1") }
else if (n == 9 & NT_theme == "bright") { c("bright purple", "bright green", "bright blue", "bright yellow", "bright red", "bright cyan", "light purple 1", "light green 1", "light blue 1") }
else if (n == 10 & NT_theme == "bright") { c("bright purple", "bright green", "bright blue", "bright yellow", "bright red", "bright cyan", "light purple 1", "light green 1", "light blue 1", "light yellow 1") }
else if (n == 11 & NT_theme == "bright") { c("bright purple", "bright green", "bright blue", "bright yellow", "bright red", "bright cyan", "light purple 1", "light green 1", "light blue 1", "light yellow 1", "light red 1") }
else if (n == 12 & NT_theme == "bright") { c("bright purple", "bright green", "bright blue", "bright yellow", "bright red", "bright cyan", "light purple 1", "light green 1", "light blue 1", "light yellow 1", "light red 1", "light cyan 1") }
else if (n == 1 & NT_theme == "purple") { "bright purple" }
else if (n == 2 & NT_theme == "purple") { c("dark purple 2", "bright purple") }
else if (n == 3 & NT_theme == "purple") { c("dark purple 2", "bright purple", "light purple 2") }
else if (n == 4 & NT_theme == "purple") { c("dark purple 2", "dark purple 1", "bright purple", "light purple 2") }
else if (n == 5 & NT_theme == "purple") { c("dark purple 2", "dark purple 1", "bright purple", "light purple 2", "light purple 1") }
else if (n == 1 & NT_theme == "blue") { "bright blue" }
else if (n == 2 & NT_theme == "blue") { c("dark blue 2", "bright blue") }
else if (n == 3 & NT_theme == "blue") { c("dark blue 2", "bright blue", "light blue 2") }
else if (n == 4 & NT_theme == "blue") { c("dark blue 2", "dark blue 1", "bright blue", "light blue 2") }
else if (n == 5 & NT_theme == "blue") { c("dark blue 2", "dark blue 1", "bright blue", "light blue 2", "light blue 1") }
else if (n == 1 & NT_theme == "red") { "bright red" }
else if (n == 2 & NT_theme == "red") { c("dark red 2", "bright red") }
else if (n == 3 & NT_theme == "red") { c("dark red 2", "bright red", "light red 2") }
else if (n == 4 & NT_theme == "red") { c("dark red 2", "dark red 1", "bright red", "light red 2") }
else if (n == 5 & NT_theme == "red") { c("dark red 2", "dark red 1", "bright red", "light red 2", "light red 1") }
else if (n == 1 & NT_theme == "yellow") { "bright yellow" }
else if (n == 2 & NT_theme == "yellow") { c("dark yellow 2", "bright yellow") }
else if (n == 3 & NT_theme == "yellow") { c("dark yellow 2", "bright yellow", "light yellow 2") }
else if (n == 4 & NT_theme == "yellow") { c("dark yellow 2", "dark yellow 1", "bright yellow", "light yellow 2") }
else if (n == 5 & NT_theme == "yellow") { c("dark yellow 2", "dark yellow 1", "bright yellow", "light yellow 2", "light yellow 1") }
else if (n == 1 & NT_theme == "green") { "bright green" }
else if (n == 2 & NT_theme == "green") { c("dark green 2", "bright green") }
else if (n == 3 & NT_theme == "green") { c("dark green 2", "bright green", "light green 2") }
else if (n == 4 & NT_theme == "green") { c("dark green 2", "dark green 1", "bright green", "light green 2") }
else if (n == 5 & NT_theme == "green") { c("dark green 2", "dark green 1", "bright green", "light green 2", "light green 1") }
else if (n == 1 & NT_theme == "cyan") { "bright cyan" }
else if (n == 2 & NT_theme == "cyan") { c("dark cyan 2", "bright cyan") }
else if (n == 3 & NT_theme == "cyan") { c("dark cyan 2", "bright cyan", "light cyan 2") }
else if (n == 4 & NT_theme == "cyan") { c("dark cyan 2", "dark cyan 1", "bright cyan", "light cyan 2") }
else if (n == 5 & NT_theme == "cyan") { c("dark cyan 2", "dark cyan 1", "bright cyan", "light cyan 2", "light cyan 1") }
return_colours <- NT_colour(colour_indices)
if (reverse) {
return_colours <- rev(NT_colour(colour_indices))
}
return(return_colours)
}
}
####################################
# NT colour scale
scale_colour_NT <- function(palette = NT_palette(NT_theme = NULL, reverse = FALSE, ...), ...) {
ggplot2::discrete_scale(
aesthetics = "colour",
scale_name = "NT1",
palette = palette,
na.value = "#9AA0AA",
...
)
}
####################################
# NT fill scale
scale_fill_NT <- function(palette = NT_palette(NT_theme = NULL, reverse = FALSE, ...), ...) {
ggplot2::discrete_scale(
aesthetics = "fill",
scale_name = "NT2",
palette = palette,
na.value = "#9AA0AA",
...
)
}
####################################
# NT ggplot theme
NT_style <- function(){
font <- "TT Arial"
family <- "sans"
theme_minimal() %+replace%
theme(
# Background elements
panel.background = element_rect(fill = "#F4F4F4", colour = "#F4F4F4"),
panel.border = element_blank(),
plot.background = element_rect(fill = "#F4F4F4", colour = "#F4F4F4"),
plot.margin = margin(t = 0.5, r = 0.5, b = 0.5, l = 0.5, unit ="cm"),
# Grid elements
axis.ticks = element_blank(),
panel.grid.major.x = element_blank(),
panel.grid.major.y = element_line(colour = "#9AA0AA", size = 0.3),
panel.grid.minor = element_blank(),
panel.spacing = unit(0.5, "cm"),
# Text elements
axis.text.x = element_text(colour = "#9AA0AA", size = 8, family = "sans", vjust = 0),
axis.text.y = element_text(colour = "#9AA0AA", size = 8, family = "sans"),
axis.title.x = element_text(margin = margin(t = 0.3, r = 0, b = 0, l = 0, unit ="cm"), colour = "#271544", size = 8, face = "bold"),
axis.title.y = element_text(margin = margin(t = 0, r = 0.3, b = 0, l = 0, unit ="cm"), colour = "#271544", size = 8, face = "bold", angle = 90),
legend.text = element_text(colour = "#271544", size = 8, face = "bold", family = "sans"),
legend.title = element_blank(),
plot.caption = element_text(margin = margin(t = 0.3, r = 0, b = 0, l = 0, unit ="cm"), colour = "#271544", size = 8, hjust = 1, vjust = 1),
plot.title = element_text(margin = margin(t = 0, r = 0, b = 0.3, l = 0, unit ="cm"), colour = "#271544", size = 10, face = "bold", hjust = 0),
plot.title.position = "plot",
strip.text = element_text(margin = margin(t = 0, r = 0, b = 0.3, l = 0, unit ="cm"), colour = "#271544", size = 8, face = "bold"),
# Legend elements
legend.background = element_blank(),
legend.box.background = element_blank(),
legend.box.margin = margin(t = 0, r = 0, b = 0, l = 0, unit ="cm"),
legend.key = element_blank(),
legend.key.size = unit(0.4, "cm"),
legend.margin = margin(t = 0, r = 0, b = 0, l = 0, unit ="cm"),
legend.position = "bottom",
legend.spacing.x = unit(0.1, "cm"),
legend.spacing.y = unit(0.1, "cm")
)
}
################################################################################
########## Import data ##########
# Convert dod to date variable
# Create cohort flag and additional flag to identify deaths in our revised 9 month cohort period
# Death quarter variable starting in March so it is quarters of the cohort period rather than calendar or fiscal quarters
# Create grouped and renamed characteristic variables
# Join on region and LA imd quintile based on patient address
# Join on LA imd quintile based on GP address
df_input <- arrow::read_feather(file = here::here("output", "input.feather")) %>%
mutate(dod_ons = as_date(dod_ons)
, cohort = case_when(dod_ons >= as_date("2019-03-01") & dod_ons <= as_date("2020-02-29") ~ 0
, dod_ons >= as_date("2020-03-01") & dod_ons <= as_date("2021-02-28") ~ 1
, TRUE ~ NA_real_)
, study_cohort = case_when(dod_ons >= as_date("2019-06-01") & dod_ons <= as_date("2020-02-29") ~ 0
, dod_ons >= as_date("2020-06-01") & dod_ons <= as_date("2021-02-28") ~ 1
, TRUE ~ NA_real_)
, study_quarter = case_when(month(dod_ons) %in% c(3, 4, 5) & year(dod_ons) == 2019 ~ 1
, month(dod_ons) %in% c(6, 7, 8) & year(dod_ons) == 2019 ~ 2
, month(dod_ons) %in% c(9, 10, 11) & year(dod_ons) == 2019 ~ 3
, (month(dod_ons) == 12 & year(dod_ons) == 2019) | (month(dod_ons) %in% c(1, 2) & year(dod_ons) == 2020) ~ 4
, month(dod_ons) %in% c(3, 4, 5) & year(dod_ons) == 2020 ~ 5
, month(dod_ons) %in% c(6, 7, 8) & year(dod_ons) == 2020 ~ 6
, month(dod_ons) %in% c(9, 10, 11) & year(dod_ons) == 2020 ~ 7
, (month(dod_ons) == 12 & year(dod_ons) == 2020) | (month(dod_ons) %in% c(1, 2) & year(dod_ons) == 2021) ~ 8)
, study_month = floor_date(dod_ons, unit = "month")
, cod_ons_3 = str_sub(cod_ons, 1, 3)
, cod_ons_4 = str_sub(cod_ons, 1, 5)
, pod_ons_new = case_when(pod_ons == "Elsewhere" | pod_ons == "Other communal establishment" ~ "Elsewhere/other"
, TRUE ~ as.character(pod_ons))
, agegrp = case_when(age >= 0 & age <= 10 ~ "00-09"
, age >= 10 & age <= 19 ~ "10-19"
, age >= 20 & age <= 29 ~ "20-29"
, age >= 30 & age <= 39 ~ "30-39"
, age >= 40 & age <= 49 ~ "40-49"
, age >= 50 & age <= 59 ~ "50-59"
, age >= 60 & age <= 69 ~ "60-69"
, age >= 70 & age <= 79 ~ "70-79"
, age >= 80 & age <= 89 ~ "80-89"
, age >= 90 ~ "90+"
, TRUE ~ NA_character_)
, ltc_count = arrow::read_feather(file = here::here("output", "input.feather")) %>% select(starts_with("ltc_")) %>% rowSums()
, ltcgrp = case_when(ltc_count < 5 ~ as.character(ltc_count)
, ltc_count >= 5 ~ "5+"
, TRUE ~ NA_character_)
, codgrp = case_when(cod_ons_4 %in% c("U071", "U072") ~ "Covid-19"
, cod_ons_3 >= "J09" & cod_ons_3 <= "J18" ~ "Flu and pneumonia"
, (cod_ons_3 >= "J00" & cod_ons_3 <= "J08") | (cod_ons_3 >= "J19" & cod_ons_3 <= "J99") ~ "Other respiratory diseases"
, cod_ons_3 %in% c("F01", "F03", "G30") ~ "Dementia and Alzheimer's disease"
, cod_ons_3 >= "I00" & cod_ons_3 <= "I99" ~ "Circulatory diseases"
, cod_ons_3 >= "C00" & cod_ons_3 <= "C99" ~ "Cancer"
, TRUE ~ "All other causes")
, palcare = ltc_palcare1
, nopalcare = ltc_palcare2
, rural_urban = case_when(rural_class %in% c(1, 2, 3, 4) ~ "Rural"
, rural_class %in% c(5, 6, 7, 8) ~ "Urban"
, TRUE ~ NA_character_)) %>%
left_join(read_csv(here::here("docs", "lookups", "msoa_lad_rgn_2020.csv")) %>%
select(msoa11cd, lad20cd, rgn20cd) %>%
rename(region = rgn20cd)
, by = c("msoa" = "msoa11cd")) %>%
left_join(read_csv(here::here("docs", "lookups", "lad_imd_2019.csv")) %>%
rename(imd_quintile_la = imd19_quintile)
, by = "lad20cd") %>%
left_join(read_csv(here::here("docs", "lookups", "msoa_lad_rgn_2020.csv")) %>%
select(msoa11cd, lad20cd) %>%
rename(la_gp = lad20cd)
, by = c("msoa" = "msoa11cd")) %>%
left_join(read_csv(here::here("docs", "lookups", "lad_imd_2019.csv")) %>%
select(lad20cd, imd19_quintile) %>%
rename(imd_quintile_la_gp = imd19_quintile)
, by = "lad20cd") %>%
mutate(imd_quintile_la = case_when(is.na(imd_quintile_la) ~ 0
, TRUE ~ imd_quintile_la)
, imd_quintile_la_gp = case_when(is.na(imd_quintile_la_gp) ~ 0
, TRUE ~ imd_quintile_la_gp))
################################################################################
########## Basic death counts ##########
# Number of deaths in each year of study
deaths_data <- df_input %>%
group_by(cohort) %>%
summarise(deaths = n()) %>%
mutate(deaths = plyr::round_any(deaths, 10))
write_csv(deaths_data, here::here("output", "describe_cohorts", "overall_death_counts", "deaths_data.csv"))
# Number of deaths by study cohort
deaths_cohort <- df_input %>%
filter(!is.na(study_cohort)) %>%
group_by(cohort) %>%
summarise(deaths = n()) %>%
mutate(deaths = plyr::round_any(deaths, 10))
write_csv(deaths_cohort, here::here("output", "describe_cohorts", "overall_death_counts", "deaths_cohort.csv"))
# Number of deaths by quarter
deaths_quarter <- df_input %>%
group_by(study_quarter) %>%
summarise(deaths = n()) %>%
mutate(deaths = plyr::round_any(deaths, 10))
write_csv(deaths_quarter, here::here("output", "describe_cohorts", "overall_death_counts", "deaths_quarter.csv"))
################################################################################
########## Plot basic death counts ##########
# Deaths by quarter
plot_deaths_quarter <- ggplot(deaths_quarter) +
geom_bar(aes(x = study_quarter, y = deaths), stat = "identity", fill = "#9F67FF") +
labs(x = "Study quarter", y = "Number of deaths") +
scale_x_continuous(breaks = seq(1, 8, 1)) +
scale_y_continuous(limits = c(0, NA), expand = c(0, 0)) +
NT_style()
ggsave(plot = plot_deaths_quarter, filename ="deaths_quarter.png", path = here::here("output", "describe_cohorts", "overall_death_counts"), height = 10, width = 13.7, units = "cm", dpi = 600)
################################################################################
########## Death counts by place ##########
# Number of deaths in each year of study by place of death
deaths_data_pod <- df_input %>%
group_by(cohort, pod_ons_new) %>%
summarise(deaths = n()) %>%
mutate(deaths = plyr::round_any(deaths, 10)
, total = sum(deaths)
, proportion = deaths / total)
write_csv(deaths_data_pod, here::here("output", "describe_cohorts", "overall_death_counts", "deaths_data_pod.csv"))
# Number of deaths by study cohort and place of death
deaths_cohort_pod <- df_input %>%
filter(!is.na(study_cohort)) %>%
group_by(cohort, pod_ons_new) %>%
summarise(deaths = n()) %>%
mutate(deaths = plyr::round_any(deaths, 10)
, total = sum(deaths)
, proportion = deaths / total)
write_csv(deaths_cohort_pod, here::here("output", "describe_cohorts", "overall_death_counts", "deaths_cohort_pod.csv"))
# Number of deaths by quarter and place of death
deaths_quarter_pod1 <- df_input %>%
group_by(study_quarter, pod_ons_new) %>%
summarise(deaths = n()) %>%
mutate(deaths = plyr::round_any(deaths, 10)
, total = sum(deaths)
, proportion = deaths / total)
write_csv(deaths_quarter_pod1, here::here("output", "describe_cohorts", "overall_death_counts", "deaths_quarter_pod.csv"))
################################################################################
########## Plot death counts by place ##########
# Plot of number of deaths by place and cohort
plot_deaths_pod_cohort <- ggplot(deaths_cohort_pod) +
geom_bar(aes(x = reorder(pod_ons_new, deaths), y = deaths, fill = factor(cohort, levels = c("1", "0"))), stat = "identity", position = "dodge", width = 0.6) +
coord_flip() +
labs(x = "Place of death", y = "Number of deaths") +
scale_y_continuous(limits = c(0, NA), expand = c(0, 0)) +
scale_fill_manual(values = c("0" = "#00C27A", "1" = "#9F67FF"), labels = c("0" = "Pre-pandemic", "1" = "Pandemic"), breaks = c("0", "1")) +
NT_style() +
theme(
axis.text.y = element_text(colour = "#9AA0AA", size = 8, family = "sans", hjust = 1),
panel.grid.major.x = element_line(colour = "#9AA0AA", size = 0.3),
panel.grid.major.y = element_blank())
ggsave(plot = plot_deaths_pod_cohort, filename ="deaths_pod_cohort.png", path = here::here("output", "describe_cohorts", "overall_death_counts"), height = 10, width = 13.7, units = "cm", dpi = 600)
# Plot of proportion of deaths by place and cohort
plot_deaths_pod_cohort_prop <- ggplot(deaths_cohort_pod) +
geom_bar(aes(x = reorder(pod_ons_new, proportion), y = proportion, fill = factor(cohort, levels = c("1", "0"))), stat = "identity", position = "dodge", width = 0.6) +
coord_flip() +
labs(x = "Place of death", y = "Proportion of deaths") +
scale_y_continuous(limits = c(0, 1), expand = c(0, 0)) +
scale_fill_manual(values = c("0" = "#00C27A", "1" = "#9F67FF"), labels = c("0" = "Pre-pandemic", "1" = "Pandemic"), breaks = c("0", "1")) +
NT_style() +
theme(
axis.text.y = element_text(colour = "#9AA0AA", size = 8, family = "sans", hjust = 1),
panel.grid.major.x = element_line(colour = "#9AA0AA", size = 0.3),
panel.grid.major.y = element_blank())
ggsave(plot = plot_deaths_pod_cohort_prop, filename ="deaths_pod_cohort_prop.png", path = here::here("output", "describe_cohorts", "overall_death_counts"), height = 10, width = 13.7, units = "cm", dpi = 600)
################################################################################
########## Death counts by place, cohort and cause of death ##########
# Number of deaths by cohort, place of death and cause of death
# Help to decide which cause of death groupings to use
deaths_cohort_pod_lcod <- df_input %>%
filter(!is.na(study_cohort)) %>%
mutate(lcod_ons_grp = case_when(cod_ons_3 >= "A00" & cod_ons_3 <= "A09" ~ "Intestinal infectious diseases"
, (cod_ons_3 >= "A15" & cod_ons_3 <= "A19") | cod_ons_3 == "B90" ~ "Tuberculosis"
, cod_ons_3 %in% c("A20", "A44") | (cod_ons_3 >= "A75" & cod_ons_3 <= "A79") | (cod_ons_3 >= "A82" & cod_ons_3 <= "A84") | cod_ons_4 == "A852" | (cod_ons_3 >= "A90" & cod_ons_3 <= "A98") | (cod_ons_3 >= "B50" & cod_ons_3 <= "B57") ~ "Vector-borne diseases and rabies"
, (cod_ons_3 >= "A33" & cod_ons_3 <= "A37") | cod_ons_4 == "A492" | cod_ons_3 %in% c("A80", "B01", "B02", "B05", "B06", "B15", "B16") | cod_ons_4 %in% c("B170", "B180", "B181") | cod_ons_3 %in% c("B26", "B91", "G14") ~ "Vaccine-preventable diseases"
, cod_ons_3 %in% c("A39", "A87") | (cod_ons_3 >= "G00" & cod_ons_3 <= "G03") ~ "Meningitis and meningococcal infection"
, cod_ons_3 >= "A40" & cod_ons_3 <= "A41" ~ "Septicaemia"
, cod_ons_3 >= "B20" & cod_ons_3 <= "B24" ~ "HIV"
, cod_ons_3 == "C15" ~ "Malignant neoplasm of oesophagus"
, cod_ons_3 == "C16" ~ "Malignant neoplasm of stomach"
, cod_ons_3 >= "C18" & cod_ons_3 <= "C21" ~ "Malignant neoplasm of colon, sigmoid, rectum and anus"
, cod_ons_3 == "C22" ~ "Malignant neoplasm of liver and intrahepatic bile ducts"
, cod_ons_3 >= "C23" & cod_ons_3 <= "C24" ~ "Malignant neoplasm of gallbladder and other parts of biliary tract"
, cod_ons_3 == "C25" ~ "Malignant neoplasm of pancreas"
, cod_ons_3 == "C32" ~ "Malignant neoplasm of larynx"
, cod_ons_3 >= "C33" & cod_ons_3 <= "C34" ~ "Malignant neoplasm of trachea, bronchus and lung"
, cod_ons_3 >= "C40" & cod_ons_3 <= "C41" ~ "Malignant neoplasm of bone and articular cartilage"
, cod_ons_3 >= "C43" & cod_ons_3 <= "C44" ~ "Melanoma and other malignant neoplasms of skin"
, cod_ons_3 == "C50" ~ "Malignant neoplasm of breast"
, cod_ons_3 >= "C53" & cod_ons_3 <= "C55" ~ "Malignant neoplasm of uterus"
, cod_ons_3 == "C56" ~ "Malignant neoplasm of ovary"
, cod_ons_3 == "C61" ~ "Malignant neoplasm of prostate"
, cod_ons_3 == "C64" ~ "Malignant neoplasm of kidney, except renal pelvis"
, cod_ons_3 == "C67" ~ "Malignant neoplasm of bladder"
, cod_ons_3 == "C71" ~ "Malignant neoplasm of brain"
, cod_ons_3 >= "C81" & cod_ons_3 <= "C96" ~ "Malignant neoplasms, stated or presumed to be primary of lymphoid, haematopoietic and related tissue"
, cod_ons_3 >= "D00" & cod_ons_3 <= "D48" ~ "In situ and benign neoplasms, and neoplasms of uncertain or unknown behaviour"
, cod_ons_3 >= "E10" & cod_ons_3 <= "E14" ~ "Diabetes"
, (cod_ons_3 >= "D50" & cod_ons_3 <= "D53") | (cod_ons_3 >= "E40" & cod_ons_3 <= "E64") ~ "Malnutrition, nutritional anaemias and other nutritional deficiencies"
, cod_ons_3 >= "E86" & cod_ons_3 <= "E87" ~ "Disorders of fluid, electrolyte and acid-base balance"
, cod_ons_3 %in% c("F01", "F03", "G30") ~ "Dementia and Alzheimer disease"
, cod_ons_3 >= "F10" & cod_ons_3 <= "F19" ~ "Mental and behavioural disorders due to psychoactive substance use"
, cod_ons_3 >= "G10" & cod_ons_3 <= "G12" ~ "Systemic atrophies primarily affecting the central nervous system"
, cod_ons_3 == "G20" ~ "Parkinson disease"
, cod_ons_3 >= "G40" & cod_ons_3 <= "G41" ~ "Epilepsy and status epilepticus"
, cod_ons_3 >= "G80" & cod_ons_3 <= "G83" ~ "Cerebral palsy and other paralytic syndromes"
, cod_ons_3 >= "I05" & cod_ons_3 <= "I09" ~ "Chronic rheumatic heart diseases"
, cod_ons_3 >= "I10" & cod_ons_3 <= "I15" ~ "Hypertensive diseases"
, cod_ons_3 >= "I20" & cod_ons_3 <= "I25" ~ "Ischaemic heart diseases"
, cod_ons_3 >= "I26" & cod_ons_3 <= "I28" ~ "Pulmonary heart disease and diseases of pulmonary circulation"
, cod_ons_3 >= "I34" & cod_ons_3 <= "I38" ~ "Nonrheumatic valve disorders and endocarditis"
, cod_ons_3 == "I42" ~ "Cardiomyopathy"
, cod_ons_3 == "I46" ~ "Cardiac arrest"
, cod_ons_3 >= "I47" & cod_ons_3 <= "I49" ~ "Cardiac arrhythmias"
, cod_ons_3 >= "I50" & cod_ons_3 <= "I51" ~ "Heart failure and complications and ill-defined heart disease"
, cod_ons_3 >= "I60" & cod_ons_3 <= "I69" ~ "Cerebrovascular diseases"
, cod_ons_3 == "I70" ~ "Atherosclerosis"
, cod_ons_3 == "I71" ~ "Aortic aneurysm and dissection"
, (cod_ons_3 >= "J00" & cod_ons_3 <= "J06") | (cod_ons_3 >= "J20" & cod_ons_3 <= "J22") ~ "Acute respiratory infections other than influenza and pneumonia"
, cod_ons_3 >= "J09" & cod_ons_3 <= "J18" ~ "Influenza and pneumonia"
, cod_ons_3 >= "J40" & cod_ons_3 <= "J47" ~ "Chronic lower respiratory diseases"
, cod_ons_3 >= "J80" & cod_ons_3 <= "J84" ~ "Pulmonary oedema and other interstitial pulmonary diseases"
, cod_ons_3 == "J96" ~ "Respiratory failure"
, (cod_ons_3 >= "K35" & cod_ons_3 <= "K46") | cod_ons_3 == "K56" ~ "Appendicitis, hernia and intestinal obstruction"
, cod_ons_3 >= "K70" & cod_ons_3 <= "K76" ~ "Cirrhosis and other diseases of liver"
, cod_ons_3 >= "M00" & cod_ons_3 <= "M99" ~ "Diseases of musculoskeletal system and connective tissue"
, cod_ons_3 >= "N00" & cod_ons_3 <= "N39" ~ "Diseases of the urinary system"
, cod_ons_3 >= "O00" & cod_ons_3 <= "O99" ~ "Pregnancy, childbirth and puerperium"
, cod_ons_3 >= "P00" & cod_ons_3 <= "P96" ~ "Certain conditions originating in the perinatal period"
, cod_ons_3 >= "Q00" & cod_ons_3 <= "Q99" ~ "Congenital malformations, deformations and chromosomal abnormalities"
, cod_ons_3 >= "V01" & cod_ons_3 <= "V89" ~ "Land transport accidents"
, cod_ons_3 >= "W00" & cod_ons_3 <= "W19" ~ "Accidental falls"
, cod_ons_3 >= "W32" & cod_ons_3 <= "W34" ~ "Non-intentional firearm discharge"
, cod_ons_3 >= "W65" & cod_ons_3 <= "W74" ~ "Accidental drowning and submersion"
, cod_ons_3 >= "W75" & cod_ons_3 <= "W84" ~ "Accidental threats to breathing"
, cod_ons_3 >= "X40" & cod_ons_3 <= "X49" ~ "Accidental poisoning"
, (cod_ons_3 >= "X60" & cod_ons_3 <= "X84") | (cod_ons_3 >= "Y10" & cod_ons_3 <= "Y34") ~ "Suicide and injury/poisoning of undetermined intent"
, cod_ons_4 == "U509" | (cod_ons_3 >= "X85" & cod_ons_3 <= "Y09") | cod_ons_4 == "Y871" ~ "Homicide and probable suicide"
, cod_ons_3 >= "R00" & cod_ons_3 <= "R99" ~ "Symptoms, signs and ill-defined conditions"
, cod_ons_4 %in% c("U071","U072", "U109") ~ "COVID-19"
, TRUE ~ "All other causes")) %>%
group_by(cohort, pod_ons_new, lcod_ons_grp) %>%
summarise(deaths = n()) %>%
mutate(deaths = plyr::round_any(deaths, 10)
, total = sum(deaths)
, proportion = deaths / total) %>%
pivot_wider(names_from = cohort, names_prefix = c("cohort_"), values_from = c(deaths, total, proportion))
write_csv(deaths_cohort_pod_lcod, here::here("output", "describe_cohorts", "overall_death_counts", "deaths_cohort_pod_lcod.csv"))
################################################################################
########## Create tables and compare to published ONS deaths ##########
# Quarterly (Mar 19 - Feb 21)
deaths_ons_quarter <- df_input %>%
filter(study_month >= as_date("2019-03-01") & study_month <= as_date("2021-02-01")) %>%
group_by(study_month, study_quarter) %>%
summarise(deaths = n()) %>%
left_join(read_csv(here::here("docs", "ons_comparison_data", "table1_sex_onsmortality.csv")) %>%
group_by(period) %>%
summarise(ons_deaths = sum(ons_deaths, na.rm = TRUE))
, by = c("study_month" = "period")) %>%
group_by(study_quarter) %>%
summarise(deaths = sum(deaths, na.rm = TRUE)
, ons_deaths = sum(ons_deaths, na.rm = TRUE)) %>%
mutate(deaths = plyr::round_any(deaths, 10)) %>%
mutate(proportion = deaths / ons_deaths)
write_csv(deaths_ons_quarter, here::here("output", "describe_cohorts", "ons_death_comparisons", "deaths_ons_quarter.csv"))
plot_deaths_ons_quarter <- ggplot(deaths_ons_quarter, aes(x = study_quarter, y = proportion)) +
geom_line(size = 1, colour = "#9F67FF") +
geom_point(fill = "#F4F4F4", colour = "#9F67FF", shape = 21, size = 1.5, stroke = 1.3) +
labs(x = "Study quarter", y = "Percent of ONS deaths") +
scale_x_continuous(expand = c(0, 1), breaks = seq(1, 8, 1)) +
scale_y_continuous(expand = c(0, 0), limits = c(0, 1), breaks = seq(0, 1, 0.1)
, labels = c("0%", "10%", "20%", "30%", "40%", "50%", "60%", "70%", "80%", "90%", "100%")) +
NT_style()
ggsave(plot = plot_deaths_ons_quarter, filename ="deaths_ons_quarter.png", path = here::here("output", "describe_cohorts", "ons_death_comparisons"), height = 10, width = 13.7, units = "cm", dpi = 600)
# Quarterly (Mar 19 - Feb 21) deaths by region
deaths_ons_quarter_region <- df_input %>%
filter(study_month >= as_date("2019-03-01") & study_month <= as_date("2021-02-01")) %>%
group_by(study_month, region, study_quarter) %>%
summarise(deaths = n()) %>%
left_join(read_csv(here::here("docs", "ons_comparison_data", "region_onsmortality.csv"))
, by = c("study_month" = "period", "region")) %>%
group_by(study_quarter, region) %>%
summarise(deaths = sum(deaths, na.rm = TRUE)
, ons_deaths = sum(ons_deaths, na.rm = TRUE)) %>%
mutate(deaths = plyr::round_any(deaths, 10)) %>%
mutate(proportion = deaths / ons_deaths)
write_csv(deaths_ons_quarter_region, here::here("output", "describe_cohorts", "ons_death_comparisons", "deaths_ons_quarter_region.csv"))
deaths_ons_quarter_region_late <- df_input %>%
filter(study_month >= as_date("2019-03-01") & study_month <= as_date("2021-02-01")) %>%
group_by(study_month, region, study_quarter) %>%
summarise(deaths = n()) %>%
left_join(read_csv(here::here("docs", "ons_comparison_data", "region_onsmortality.csv"))
, by = c("study_month" = "period", "region")) %>%
group_by(study_quarter, region) %>%
summarise(deaths = sum(deaths, na.rm = TRUE)
, ons_deaths = sum(ons_deaths, na.rm = TRUE)) %>%
mutate(deaths = plyr::round_any(deaths, 10)) %>%
mutate(proportion = deaths / ons_deaths) %>%
filter(study_quarter >= 5)
write_csv(deaths_ons_quarter_region_late, here::here("output", "describe_cohorts", "ons_death_comparisons", "deaths_ons_quarter_region_late.csv"))
plot_deaths_ons_quarter_region <- ggplot(deaths_ons_quarter_region %>% filter(str_detect(region, "^E12"))
, aes(x = study_quarter, y = proportion, colour = region)) +
geom_line(size = 1) +
geom_point(fill = "#F4F4F4", shape = 21, size = 1.5, stroke = 1.3) +
labs(x = "Study quarter", y = "Percent of ONS deaths") +
scale_colour_NT(palette = NT_palette()) +
scale_x_continuous(expand = c(0, 0.5), breaks = seq(1, 8, 1)) +
scale_y_continuous(expand = c(0, 0), limits = c(0, 1), breaks = seq(0, 1, 0.1)
, labels = c("0%", "10%", "20%", "30%", "40%", "50%", "60%", "70%", "80%", "90%", "100%")) +
NT_style()
ggsave(plot = plot_deaths_ons_quarter_region, filename ="deaths_ons_quarter_region.png", path = here::here("output", "describe_cohorts", "ons_death_comparisons"), height = 10, width = 13.7, units = "cm", dpi = 600)
# Quarterly (Mar 19 - Feb 21) deaths by sex - Table 1
deaths_ons_quarter_sex <- df_input %>%
filter(study_month >= as_date("2019-03-01") & study_month <= as_date("2021-02-01")) %>%
group_by(study_month, sex, study_quarter) %>%
summarise(deaths = n()) %>%
left_join(read_csv(here::here("docs", "ons_comparison_data", "table1_sex_onsmortality.csv"))
, by = c("study_month" = "period", "sex")) %>%
group_by(study_quarter, sex) %>%
summarise(deaths = sum(deaths, na.rm = TRUE)
, ons_deaths = sum(ons_deaths, na.rm = TRUE)) %>%
mutate(deaths = plyr::round_any(deaths, 10)) %>%
mutate(proportion = deaths / ons_deaths)
write_csv(deaths_ons_quarter_sex, here::here("output", "describe_cohorts", "ons_death_comparisons", "deaths_ons_quarter_sex.csv"))
plot_deaths_ons_quarter_sex <- ggplot(deaths_ons_quarter_sex %>% filter(sex %in% c("M", "F")), aes(x = study_quarter, y = proportion, colour = sex)) +
geom_line(size = 1) +
geom_point(fill = "#F4F4F4", shape = 21, size = 1.5, stroke = 1.3) +
labs(x = "Study quarter", y = "Percent of ONS deaths") +
scale_colour_NT(palette = NT_palette()) +
scale_x_continuous(expand = c(0, 1), breaks = seq(1, 8, 1)) +
scale_y_continuous(expand = c(0, 0), limits = c(0, 1), breaks = seq(0, 1, 0.1)
, labels = c("0%", "10%", "20%", "30%", "40%", "50%", "60%", "70%", "80%", "90%", "100%")) +
NT_style()
ggsave(plot = plot_deaths_ons_quarter_sex, filename ="deaths_ons_quarter_sex.png", path = here::here("output", "describe_cohorts", "ons_death_comparisons"), height = 10, width = 13.7, units = "cm", dpi = 600)
# Quarterly deaths (Mar 19 - Feb 21) by age group (<75, 75-79, 80-84, 85-89, 90+) - Table 4, 8c
deaths_ons_quarter_agegrp <- df_input %>%
filter(study_month >= as_date("2019-03-01") & study_month <= as_date("2021-02-01")) %>%
mutate(agegrp_ons = case_when(age >= 0 & age <= 74 ~ "<75"
, age >= 75 & age <= 79 ~ "75-79"
, age >= 80 & age <= 84 ~ "80-84"
, age >= 85 & age <= 89 ~ "85-89"
, age >= 90 ~ "90+"
, TRUE ~ NA_character_)) %>%
group_by(study_month, agegrp_ons, study_quarter) %>%
summarise(deaths = n()) %>%
left_join(read_csv(here::here("docs", "ons_comparison_data", "table4_8c_agegrp_onsmortality.csv"))
, by = c("study_month" = "period", "agegrp_ons" = "agegrp")) %>%
group_by(study_quarter, agegrp_ons) %>%
summarise(deaths = sum(deaths, na.rm = TRUE)
, ons_deaths = sum(ons_deaths, na.rm = TRUE)) %>%
mutate(deaths = plyr::round_any(deaths, 10)) %>%
mutate(proportion = deaths / ons_deaths)
write_csv(deaths_ons_quarter_agegrp, here::here("output", "describe_cohorts", "ons_death_comparisons", "deaths_ons_quarter_agegrp.csv"))
plot_deaths_ons_quarter_agegrp <- ggplot(deaths_ons_quarter_agegrp %>% filter(!is.na(agegrp_ons)), aes(x = study_quarter, y = proportion, colour = agegrp_ons)) +
geom_line(size = 1) +
geom_point(fill = "#F4F4F4", shape = 21, size = 1.5, stroke = 1.3) +
labs(x = "Study quarter", y = "Percent of ONS deaths") +
scale_colour_NT(palette = NT_palette()) +
scale_x_continuous(expand = c(0, 1), breaks = seq(1, 8, 1)) +
scale_y_continuous(expand = c(0, 0), limits = c(0, 1), breaks = seq(0, 1, 0.1)
, labels = c("0%", "10%", "20%", "30%", "40%", "50%", "60%", "70%", "80%", "90%", "100%")) +
NT_style()
ggsave(plot = plot_deaths_ons_quarter_agegrp, filename ="deaths_ons_quarter_agegrp.png", path = here::here("output", "describe_cohorts", "ons_death_comparisons"), height = 10, width = 13.7, units = "cm", dpi = 600)
# Quarterly deaths (Mar 19 - Feb 21) by leading (top 10) cause of death - Table 11a
# Deaths for 2019 are by date of occurrence
# ONS cause of death groupings
# Check the categories mutually exclusive particularly around covid-19 addition
# Check how 4+ character codes appear - with or without "."
deaths_ons_quarter_lcod <- df_input %>%
filter(study_month >= as_date("2019-03-01") & study_month <= as_date("2021-02-01")) %>%
mutate(lcod_ons_grp = case_when(cod_ons_3 >= "A00" & cod_ons_3 <= "A09" ~ "Intestinal infectious diseases"
, (cod_ons_3 >= "A15" & cod_ons_3 <= "A19") | cod_ons_3 == "B90" ~ "Tuberculosis"
, cod_ons_3 %in% c("A20", "A44") | (cod_ons_3 >= "A75" & cod_ons_3 <= "A79") | (cod_ons_3 >= "A82" & cod_ons_3 <= "A84") | cod_ons_4 == "A852" | (cod_ons_3 >= "A90" & cod_ons_3 <= "A98") | (cod_ons_3 >= "B50" & cod_ons_3 <= "B57") ~ "Vector-borne diseases and rabies"
, (cod_ons_3 >= "A33" & cod_ons_3 <= "A37") | cod_ons_4 == "A492" | cod_ons_3 %in% c("A80", "B01", "B02", "B05", "B06", "B15", "B16") | cod_ons_4 %in% c("B170", "B180", "B181") | cod_ons_3 %in% c("B26", "B91", "G14") ~ "Vaccine-preventable diseases"
, cod_ons_3 %in% c("A39", "A87") | (cod_ons_3 >= "G00" & cod_ons_3 <= "G03") ~ "Meningitis and meningococcal infection"
, cod_ons_3 >= "A40" & cod_ons_3 <= "A41" ~ "Septicaemia"
, cod_ons_3 >= "B20" & cod_ons_3 <= "B24" ~ "HIV"
, cod_ons_3 == "C15" ~ "Malignant neoplasm of oesophagus"
, cod_ons_3 == "C16" ~ "Malignant neoplasm of stomach"
, cod_ons_3 >= "C18" & cod_ons_3 <= "C21" ~ "Malignant neoplasm of colon, sigmoid, rectum and anus"
, cod_ons_3 == "C22" ~ "Malignant neoplasm of liver and intrahepatic bile ducts"
, cod_ons_3 >= "C23" & cod_ons_3 <= "C24" ~ "Malignant neoplasm of gallbladder and other parts of biliary tract"
, cod_ons_3 == "C25" ~ "Malignant neoplasm of pancreas"
, cod_ons_3 == "C32" ~ "Malignant neoplasm of larynx"
, cod_ons_3 >= "C33" & cod_ons_3 <= "C34" ~ "Malignant neoplasm of trachea, bronchus and lung"
, cod_ons_3 >= "C40" & cod_ons_3 <= "C41" ~ "Malignant neoplasm of bone and articular cartilage"
, cod_ons_3 >= "C43" & cod_ons_3 <= "C44" ~ "Melanoma and other malignant neoplasms of skin"
, cod_ons_3 == "C50" ~ "Malignant neoplasm of breast"
, cod_ons_3 >= "C53" & cod_ons_3 <= "C55" ~ "Malignant neoplasm of uterus"
, cod_ons_3 == "C56" ~ "Malignant neoplasm of ovary"
, cod_ons_3 == "C61" ~ "Malignant neoplasm of prostate"
, cod_ons_3 == "C64" ~ "Malignant neoplasm of kidney, except renal pelvis"
, cod_ons_3 == "C67" ~ "Malignant neoplasm of bladder"
, cod_ons_3 == "C71" ~ "Malignant neoplasm of brain"
, cod_ons_3 >= "C81" & cod_ons_3 <= "C96" ~ "Malignant neoplasms, stated or presumed to be primary of lymphoid, haematopoietic and related tissue"
, cod_ons_3 >= "D00" & cod_ons_3 <= "D48" ~ "In situ and benign neoplasms, and neoplasms of uncertain or unknown behaviour"
, cod_ons_3 >= "E10" & cod_ons_3 <= "E14" ~ "Diabetes"
, (cod_ons_3 >= "D50" & cod_ons_3 <= "D53") | (cod_ons_3 >= "E40" & cod_ons_3 <= "E64") ~ "Malnutrition, nutritional anaemias and other nutritional deficiencies"
, cod_ons_3 >= "E86" & cod_ons_3 <= "E87" ~ "Disorders of fluid, electrolyte and acid-base balance"
, cod_ons_3 %in% c("F01", "F03", "G30") ~ "Dementia and Alzheimer disease"
, cod_ons_3 >= "F10" & cod_ons_3 <= "F19" ~ "Mental and behavioural disorders due to psychoactive substance use"
, cod_ons_3 >= "G10" & cod_ons_3 <= "G12" ~ "Systemic atrophies primarily affecting the central nervous system"
, cod_ons_3 == "G20" ~ "Parkinson disease"
, cod_ons_3 >= "G40" & cod_ons_3 <= "G41" ~ "Epilepsy and status epilepticus"
, cod_ons_3 >= "G80" & cod_ons_3 <= "G83" ~ "Cerebral palsy and other paralytic syndromes"
, cod_ons_3 >= "I05" & cod_ons_3 <= "I09" ~ "Chronic rheumatic heart diseases"
, cod_ons_3 >= "I10" & cod_ons_3 <= "I15" ~ "Hypertensive diseases"
, cod_ons_3 >= "I20" & cod_ons_3 <= "I25" ~ "Ischaemic heart diseases"
, cod_ons_3 >= "I26" & cod_ons_3 <= "I28" ~ "Pulmonary heart disease and diseases of pulmonary circulation"
, cod_ons_3 >= "I34" & cod_ons_3 <= "I38" ~ "Nonrheumatic valve disorders and endocarditis"
, cod_ons_3 == "I42" ~ "Cardiomyopathy"
, cod_ons_3 == "I46" ~ "Cardiac arrest"
, cod_ons_3 >= "I47" & cod_ons_3 <= "I49" ~ "Cardiac arrhythmias"
, cod_ons_3 >= "I50" & cod_ons_3 <= "I51" ~ "Heart failure and complications and ill-defined heart disease"
, cod_ons_3 >= "I60" & cod_ons_3 <= "I69" ~ "Cerebrovascular diseases"
, cod_ons_3 == "I70" ~ "Atherosclerosis"
, cod_ons_3 == "I71" ~ "Aortic aneurysm and dissection"
, (cod_ons_3 >= "J00" & cod_ons_3 <= "J06") | (cod_ons_3 >= "J20" & cod_ons_3 <= "J22") ~ "Acute respiratory infections other than influenza and pneumonia"
, cod_ons_3 >= "J09" & cod_ons_3 <= "J18" ~ "Influenza and pneumonia"
, cod_ons_3 >= "J40" & cod_ons_3 <= "J47" ~ "Chronic lower respiratory diseases"
, cod_ons_3 >= "J80" & cod_ons_3 <= "J84" ~ "Pulmonary oedema and other interstitial pulmonary diseases"
, cod_ons_3 == "J96" ~ "Respiratory failure"
, (cod_ons_3 >= "K35" & cod_ons_3 <= "K46") | cod_ons_3 == "K56" ~ "Appendicitis, hernia and intestinal obstruction"
, cod_ons_3 >= "K70" & cod_ons_3 <= "K76" ~ "Cirrhosis and other diseases of liver"
, cod_ons_3 >= "M00" & cod_ons_3 <= "M99" ~ "Diseases of musculoskeletal system and connective tissue"
, cod_ons_3 >= "N00" & cod_ons_3 <= "N39" ~ "Diseases of the urinary system"
, cod_ons_3 >= "O00" & cod_ons_3 <= "O99" ~ "Pregnancy, childbirth and puerperium"
, cod_ons_3 >= "P00" & cod_ons_3 <= "P96" ~ "Certain conditions originating in the perinatal period"
, cod_ons_3 >= "Q00" & cod_ons_3 <= "Q99" ~ "Congenital malformations, deformations and chromosomal abnormalities"
, cod_ons_3 >= "V01" & cod_ons_3 <= "V89" ~ "Land transport accidents"
, cod_ons_3 >= "W00" & cod_ons_3 <= "W19" ~ "Accidental falls"
, cod_ons_3 >= "W32" & cod_ons_3 <= "W34" ~ "Non-intentional firearm discharge"
, cod_ons_3 >= "W65" & cod_ons_3 <= "W74" ~ "Accidental drowning and submersion"
, cod_ons_3 >= "W75" & cod_ons_3 <= "W84" ~ "Accidental threats to breathing"
, cod_ons_3 >= "X40" & cod_ons_3 <= "X49" ~ "Accidental poisoning"
, (cod_ons_3 >= "X60" & cod_ons_3 <= "X84") | (cod_ons_3 >= "Y10" & cod_ons_3 <= "Y34") ~ "Suicide and injury/poisoning of undetermined intent"
, cod_ons_4 == "U509" | (cod_ons_3 >= "X85" & cod_ons_3 <= "Y09") | cod_ons_4 == "Y871" ~ "Homicide and probable suicide"
, cod_ons_3 >= "R00" & cod_ons_3 <= "R99" ~ "Symptoms, signs and ill-defined conditions"
, cod_ons_4 %in% c("U071","U072", "U109") ~ "COVID-19"
, TRUE ~ "All other causes")) %>%
filter(lcod_ons_grp != "All other causes") %>%
group_by(study_month, lcod_ons_grp, study_quarter) %>%
summarise(deaths = n()) %>%
mutate(lcod_ons_grp = tolower(lcod_ons_grp)) %>%
left_join(read_csv(here::here("docs", "ons_comparison_data", "table11a_cod_onsmortality.csv"))
, by = c("study_month" = "period", "lcod_ons_grp" = "cause")) %>%
group_by(study_quarter, lcod_ons_grp) %>%
summarise(deaths = sum(deaths, na.rm = TRUE)
, ons_deaths = sum(ons_deaths, na.rm = TRUE)) %>%
arrange(study_quarter, desc(deaths)) %>%
mutate(rank = row_number()) %>%
arrange(study_quarter, desc(ons_deaths)) %>%
mutate(rank_ons = row_number()) %>%
mutate(deaths = plyr::round_any(deaths, 10)) %>%
mutate(proportion = deaths / ons_deaths) %>%
arrange(study_quarter, rank)
write_csv(deaths_ons_quarter_lcod, here::here("output", "describe_cohorts", "ons_death_comparisons", "deaths_ons_quarter_lcod.csv"))
# Monthly deaths (Jan 20 - Feb 21) by place of death - Table 14a
deaths_ons_month_pod <- df_input %>%
filter(study_month >= as_date("2020-01-01") & study_month <= as_date("2021-02-01")) %>%
group_by(study_month, pod_ons) %>%
summarise(deaths = n()) %>%
mutate(deaths = plyr::round_any(deaths, 10)) %>%
left_join(read_csv(here::here("docs", "ons_comparison_data", "table14a_pod_onsmortality.csv"))
, by = c("study_month" = "period", "pod_ons" = "place_of_death")) %>%
mutate(proportion = deaths / ons_deaths)
write_csv(deaths_ons_month_pod, here::here("output", "describe_cohorts", "ons_death_comparisons", "deaths_ons_month_pod.csv"))
plot_deaths_ons_month_pod <- ggplot(deaths_ons_month_pod %>% filter(pod_ons %in% c("Hospital", "Care home", "Home", "Hospice", "Elsewhere", "Other communal establishment"))
, aes(x = study_month, y = proportion, colour = pod_ons)) +
geom_line(size = 1) +
geom_point(fill = "#F4F4F4", shape = 21, size = 1.5, stroke = 1.3) +
labs(x = "Month", y = "Percent of ONS deaths") +
scale_colour_NT(palette = NT_palette()) +
scale_x_date(expand = c(0, 1), date_breaks = "month", date_labels = "%b %y") +
scale_y_continuous(expand = c(0, 0), limits = c(0, 1), breaks = seq(0, 1, 0.1)
, labels = c("0%", "10%", "20%", "30%", "40%", "50%", "60%", "70%", "80%", "90%", "100%")) +
NT_style() +
theme(axis.text.x = element_text(angle = 45, vjust = 1, hjust = 1))
ggsave(plot = plot_deaths_ons_month_pod, filename ="deaths_ons_month_pod.png", path = here::here("output", "describe_cohorts", "ons_death_comparisons"), height = 10, width = 13.7, units = "cm", dpi = 600)
################################################################################
########## Number of deaths by cohort and characteristic ##########
# Ratio - place of death
death_ratio_pod <- df_input %>%
filter(!is.na(study_cohort)) %>%
group_by(cohort, pod_ons_new) %>%
summarise(deaths = n()) %>%
mutate(deaths = plyr::round_any(deaths, 10)
, total = sum(deaths)
, proportion = deaths / total) %>%
select(-total) %>%
pivot_wider(names_from = cohort, names_prefix = c("cohort_"), values_from = c(deaths, proportion)) %>%
mutate(ratio_deaths = deaths_cohort_1 / deaths_cohort_0
, ratio_proportion = proportion_cohort_1 / proportion_cohort_0)
write_csv(death_ratio_pod, here::here("output", "describe_cohorts", "death_ratios_cohort", "death_ratio_cohort_pod.csv"))
# Ratio - cause of death
death_ratio_cod <- df_input %>%
filter(!is.na(study_cohort)) %>%
group_by(cohort, codgrp) %>%
summarise(deaths = n()) %>%
mutate(deaths = plyr::round_any(deaths, 10)
, total = sum(deaths)
, proportion = deaths / total) %>%
select(-total) %>%
pivot_wider(names_from = cohort, names_prefix = c("cohort_"), values_from = c(deaths, proportion)) %>%
mutate(ratio_deaths = deaths_cohort_1 / deaths_cohort_0
, ratio_proportion = proportion_cohort_1 / proportion_cohort_0)
write_csv(death_ratio_cod, here::here("output", "describe_cohorts", "death_ratios_cohort", "death_ratio_cohort_cod.csv"))
# Ratio - sex
death_ratio_sex <- df_input %>%
filter(!is.na(study_cohort)) %>%
group_by(cohort, sex) %>%
summarise(deaths = n()) %>%
mutate(deaths = plyr::round_any(deaths, 10)
, total = sum(deaths)
, proportion = deaths / total) %>%
select(-total) %>%
pivot_wider(names_from = cohort, names_prefix = c("cohort_"), values_from = c(deaths, proportion)) %>%
mutate(ratio_deaths = deaths_cohort_1 / deaths_cohort_0
, ratio_proportion = proportion_cohort_1 / proportion_cohort_0)
write_csv(death_ratio_sex, here::here("output", "describe_cohorts", "death_ratios_cohort", "death_ratio_cohort_sex.csv"))
# Ratio - age group
death_ratio_agegrp <- df_input %>%
filter(!is.na(study_cohort)) %>%
group_by(cohort, agegrp) %>%
summarise(deaths = n()) %>%
mutate(deaths = plyr::round_any(deaths, 10)
, total = sum(deaths)
, proportion = deaths / total) %>%
select(-total) %>%
pivot_wider(names_from = cohort, names_prefix = c("cohort_"), values_from = c(deaths, proportion)) %>%
mutate(ratio_deaths = deaths_cohort_1 / deaths_cohort_0
, ratio_proportion = proportion_cohort_1 / proportion_cohort_0)
write_csv(death_ratio_agegrp, here::here("output", "describe_cohorts", "death_ratios_cohort", "death_ratio_cohort_agegrp.csv"))
# Ratio - ethnicity
death_ratio_ethnicity <- df_input %>%
filter(!is.na(study_cohort)) %>%
group_by(cohort, ethnicity) %>%
summarise(deaths = n()) %>%
mutate(deaths = plyr::round_any(deaths, 10)
, total = sum(deaths)
, proportion = deaths / total) %>%
select(-total) %>%
pivot_wider(names_from = cohort, names_prefix = c("cohort_"), values_from = c(deaths, proportion)) %>%
mutate(ratio_deaths = deaths_cohort_1 / deaths_cohort_0
, ratio_proportion = proportion_cohort_1 / proportion_cohort_0)
write_csv(death_ratio_ethnicity, here::here("output", "describe_cohorts", "death_ratios_cohort", "death_ratio_cohort_ethnicity.csv"))
# Ratio - ethnicity GP
death_ratio_ethnicity_gp <- df_input %>%
filter(!is.na(study_cohort)) %>%
group_by(cohort, ethnicity_gp) %>%
summarise(deaths = n()) %>%
mutate(deaths = plyr::round_any(deaths, 10)
, total = sum(deaths)
, proportion = deaths / total) %>%
select(-total) %>%
pivot_wider(names_from = cohort, names_prefix = c("cohort_"), values_from = c(deaths, proportion)) %>%
mutate(ratio_deaths = deaths_cohort_1 / deaths_cohort_0
, ratio_proportion = proportion_cohort_1 / proportion_cohort_0)
write_csv(death_ratio_ethnicity_gp, here::here("output", "describe_cohorts", "death_ratios_cohort", "death_ratio_cohort_ethnicity_gp.csv"))
# Ratio - ethnicity SUS
death_ratio_ethnicity_sus <- df_input %>%
filter(!is.na(study_cohort)) %>%
group_by(cohort, ethnicity_sus) %>%
summarise(deaths = n()) %>%
mutate(deaths = plyr::round_any(deaths, 10)
, total = sum(deaths)
, proportion = deaths / total) %>%
select(-total) %>%
pivot_wider(names_from = cohort, names_prefix = c("cohort_"), values_from = c(deaths, proportion)) %>%
mutate(ratio_deaths = deaths_cohort_1 / deaths_cohort_0
, ratio_proportion = proportion_cohort_1 / proportion_cohort_0)
write_csv(death_ratio_ethnicity_sus, here::here("output", "describe_cohorts", "death_ratios_cohort", "death_ratio_cohort_ethnicity_sus.csv"))
# Ratio - long term conditions
death_ratio_ltc <- df_input %>%
filter(!is.na(study_cohort)) %>%
group_by(cohort, ltcgrp) %>%
summarise(deaths = n()) %>%
mutate(deaths = plyr::round_any(deaths, 10)
, total = sum(deaths)
, proportion = deaths / total) %>%
select(-total) %>%
pivot_wider(names_from = cohort, names_prefix = c("cohort_"), values_from = c(deaths, proportion)) %>%
mutate(ratio_deaths = deaths_cohort_1 / deaths_cohort_0
, ratio_proportion = proportion_cohort_1 / proportion_cohort_0)
write_csv(death_ratio_ltc, here::here("output", "describe_cohorts", "death_ratios_cohort", "death_ratio_cohort_ltc.csv"))
# Ratio - palliative care
death_ratio_palcare <- df_input %>%
filter(!is.na(study_cohort)) %>%
group_by(cohort, palcare) %>%
summarise(deaths = n()) %>%
mutate(deaths = plyr::round_any(deaths, 10)
, total = sum(deaths)
, proportion = deaths / total) %>%
select(-total) %>%
pivot_wider(names_from = cohort, names_prefix = c("cohort_"), values_from = c(deaths, proportion)) %>%
mutate(ratio_deaths = deaths_cohort_1 / deaths_cohort_0
, ratio_proportion = proportion_cohort_1 / proportion_cohort_0)
write_csv(death_ratio_palcare, here::here("output", "describe_cohorts", "death_ratios_cohort", "death_ratio_cohort_palcare.csv"))
# Ratio - no palliative care
death_ratio_nopalcare <- df_input %>%
filter(!is.na(study_cohort)) %>%
group_by(cohort, nopalcare) %>%
summarise(deaths = n()) %>%
mutate(deaths = plyr::round_any(deaths, 10)
, total = sum(deaths)
, proportion = deaths / total) %>%
select(-total) %>%
pivot_wider(names_from = cohort, names_prefix = c("cohort_"), values_from = c(deaths, proportion)) %>%
mutate(ratio_deaths = deaths_cohort_1 / deaths_cohort_0
, ratio_proportion = proportion_cohort_1 / proportion_cohort_0)
write_csv(death_ratio_nopalcare, here::here("output", "describe_cohorts", "death_ratios_cohort", "death_ratio_cohort_nopalcare.csv"))
# Ratio - care home type
death_ratio_carehome <- df_input %>%
filter(!is.na(study_cohort)) %>%
group_by(cohort, carehome) %>%
summarise(deaths = n()) %>%
mutate(deaths = plyr::round_any(deaths, 10)
, total = sum(deaths)
, proportion = deaths / total) %>%
select(-total) %>%
pivot_wider(names_from = cohort, names_prefix = c("cohort_"), values_from = c(deaths, proportion)) %>%
mutate(ratio_deaths = deaths_cohort_1 / deaths_cohort_0
, ratio_proportion = proportion_cohort_1 / proportion_cohort_0)
write_csv(death_ratio_carehome, here::here("output", "describe_cohorts", "death_ratios_cohort", "death_ratio_cohort_carehome.csv"))
# Ratio - Region
death_ratio_region <- df_input %>%
filter(!is.na(study_cohort)) %>%
group_by(cohort, region) %>%
summarise(deaths = n()) %>%
mutate(deaths = plyr::round_any(deaths, 10)
, total = sum(deaths)
, proportion = deaths / total) %>%
select(-total) %>%
pivot_wider(names_from = cohort, names_prefix = c("cohort_"), values_from = c(deaths, proportion)) %>%
mutate(ratio_deaths = deaths_cohort_1 / deaths_cohort_0
, ratio_proportion = proportion_cohort_1 / proportion_cohort_0)
write_csv(death_ratio_region, here::here("output", "describe_cohorts", "death_ratios_cohort", "death_ratio_cohort_region.csv"))