Discuss masking and handling of low quality data

[dmaccannell]

Primer erosion with omicron is showing itself to be fairly important. In some cases, masking problematic amplicons may help improve the interpretability of the data. Is it worth bringing that out here? Hard to without a fairly detailed tour through the various amplicon strategies and how they're faring.

[kevinlibuit]

I think so, yes. This should be noted in both the bioinformatics resources and omircon-specific doc.

Do you have any resources we could link to regarding both impact and suggested bioinformatics approach?