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Interaction Tests with GLOW #530

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jjfarrell opened this issue May 18, 2023 · 1 comment
Open

Interaction Tests with GLOW #530

jjfarrell opened this issue May 18, 2023 · 1 comment
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enhancement New feature or request

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@jjfarrell
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Can GLOW run interaction tests for a gwas analyses? Regenie presently can perform interaction tests (GxE, GxG). If that is not yet available in GLOW, could that be ported to GLOW?
@williambrandler
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@jjfarrell it could be possible to do this with the Glow Pipe Transformer

for example if you joined the variants to the --interaction-snp-file, partitioned on the set of interacting SNPs you want to test and then fed the resulting dataframe through the pipe transformer, running regenie on the command line for each partition

@henrydavidge what do you think?

@henrydavidge henrydavidge added the enhancement New feature or request label Mar 22, 2024
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@henrydavidge @jjfarrell @williambrandler