measurement_method_20240413_v2.131.obo

format-version: 1.2
data-version: 2.131
date: 13:04:2024 20:13
saved-by: jrsmith
auto-generated-by: --RGD OBO FILE GENERATOR -- build 2023-05-30 --
synonymtypedef: DISPLAY_SYNONYM "term name abbreviation, used for display" EXACT
default-namespace: measurement_method_ontology
ontology: mmo

[Term]
id: MMO:0000000
name: measurement method
def: "The manner, procedure or technique by which a morphological or physiological state or property in a single individual or sample or a group of individuals or samples is assessed and a quantitative or qualitative value assigned." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:22654893]

[Term]
id: MMO:0000001
name: electrical potential recording method
def: "A method using the work per unit charge necessary to move a charge body in an electric field from a reference point to make or calculate the measurement of interest." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000026 ! in vivo method

[Term]
id: MMO:0000002
name: transthoracic echocardiography
def: "Method of graphically recording position and motion of walls and internal structures of the heart and neighboring tissue through the echo obtained from beams of ultrasonic waves directed through the chest wall." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "echocardiography" RELATED []
synonym: "TTE" RELATED []
synonym: "ultrasonic cardiography" RELATED []
is_a: MMO:0000337 ! echocardiography

[Term]
id: MMO:0000003
name: electrocardiography
def: "Any procedure for making graphic records of the variations in electrical potential caused by electrical activity of the heart muscle. Activity is usually detected at the body surface, but may be detected in other ways. ECG is used to study the action of the heart muscle." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "ECG" RELATED []
synonym: "EKG" RELATED []
is_a: MMO:0000001 ! electrical potential recording method

[Term]
id: MMO:0000004
name: isolated body part method
def: "The manner, procedure or technique by which a morphological or physiological state or property in an isolated body part is assessed and a quantitative or qualitative value assigned. An isolated body part is a subdivision of the material or physical structure of an organism, such as an organ, extremity or tissue, after it has been removed from the body." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:22654893]
is_a: MMO:0000027 ! ex vivo method
created_by: mshimoyama
creation_date: 2010-06-29T08:03:34Z

[Term]
id: MMO:0000005
name: post excision weight measurement
def: "Any method for measuring the weight of an organ, tissue or other body part after it has been removed from the body. The weight of an object is its heaviness, that is, the force exerted on it by gravitational force which is proportional to its mass." [Mosby:Mosbys_Dental_Dictionary--2nd_Ed]
is_a: MMO:0000277 ! isolated body part size method
created_by: mshimoyama
creation_date: 2010-06-29T08:03:50Z

[Term]
id: MMO:0000006
name: Shimadzu electronic balance post excision weight measurement
def: "Use of a Shimadzu electronic balance for measuring the weight of an organ, tissue or other body part after it has been removed from the body. The weight of an object is its heaviness, that is, the force exerted on it by gravitational force which is proportional to its mass." [Mosby:Mosbys_Dental_Dictionary--2nd_Ed]
is_a: MMO:0000005 ! post excision weight measurement
created_by: mshimoyama
creation_date: 2010-06-29T03:39:00Z

[Term]
id: MMO:0000007
name: continuous flow air displacement plethysmography
is_a: MMO:0000130 ! air displacement plethysmography
created_by: mshimoyama
creation_date: 2011-10-04T03:19:11Z

[Term]
id: MMO:0000008
name: photoplethysmography
def: "A technique for assessing blood flow by placing an infrared emitting diode along with a sensor, on the surface of the skin over a blood vessel with the amount of light reflected back to the sensor being inversely proportional to the number of red blood cells flowing through the vessel." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000076 ! plethysmography

[Term]
id: MMO:0000009
name: piezoplethysmography
def: "A technique that utilizes piezoelectric ceramic crystals with a sensor for assessing blood flow by placing the apparatus on the skin above a blood vessel." [http://www.kentscientifc.com "Kent"]
is_a: MMO:0000076 ! plethysmography

[Term]
id: MMO:0000010
name: volume pressure recording
is_a: MMO:0000026 ! in vivo method

[Term]
id: MMO:0000011
name: vascular indwelling catheter method
def: "A thin tube communicating to the body surface, inserted into the vascular system and positioned to permit measurements of blood flow, pressure or blood sampling over a period of time." [MedicalGlossary:www.medicalglossary.org]
is_a: MMO:0000026 ! in vivo method

[Term]
id: MMO:0000012
name: vascular balloon tipped catheter
def: "A catheter whose tip is provided with an inflatable balloon that holds the catheter in place or is used to dilate the lumen of a vessel." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000013 ! vascular fluid filled catheter

[Term]
id: MMO:0000013
name: vascular fluid filled catheter
def: "An intravascular catheter connected by a fluid-filled tube to an external pressure transducer, often used to measure intravascular pressure." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000011 ! vascular indwelling catheter method

[Term]
id: MMO:0000014
name: vascular transducer tipped catheter
is_a: MMO:0000011 ! vascular indwelling catheter method

[Term]
id: MMO:0000015
name: radiotelemetry
def: "A method in which a measurement is made at a distance from the organism or part of the organism with the measurable evidence being transmitted by radio signals from the organism to the recording apparatus." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000026 ! in vivo method

[Term]
id: MMO:0000016
name: body weighing method
is_a: MMO:0000119 ! body measuring method

[Term]
id: MMO:0000017
name: whole body digital scale
alt_id: MMO:0000035
def: "A digital scale which is appropriate for use in weighing the entire body of an animal or a human." [RGD:JRS]
synonym: "digital scale" EXACT []
is_a: MMO:0000217 ! scale

[Term]
id: MMO:0000018
name: fluoroimmunoassay
def: "A method for quantitative determination of chemical substances using a fluorochrome-labeled antibody or antigen." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "FEIA" EXACT []
synonym: "fluorescent enzyme immunoassay" EXACT []
is_a: MMO:0000713 ! enzyme immunoassay
created_by: mshimoyama
creation_date: 2010-07-27T03:10:14Z

[Term]
id: MMO:0000019
name: magnetic resonance imaging
def: "A method of visualizing soft tissues of the body by applying an external magnetic field that makes it possible to distinguish between hydrogen atoms in different environments. MRI is a medical application of nuclear magnetic resonance (NMR)." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "MRI" EXACT []
synonym: "nuclear magnetic resonance imaging" RELATED []
is_a: MMO:0000709 ! nuclear magnetic resonance spectroscopy

[Term]
id: MMO:0000020
name: intravascular electromagnetic flow sensor
is_a: MMO:0000011 ! vascular indwelling catheter method

[Term]
id: MMO:0000021
name: laser Doppler flowmetry
def: "A method to measure the rate of flow of liquids or gases using a laser beam in which the light is shifted by moving objects in the fluid in accordance with the Doppler effect and the scattered light is detected with a photodetector." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000317 ! flowmetry

[Term]
id: MMO:0000022
name: stop flow air displacement plethysmography
is_a: MMO:0000130 ! air displacement plethysmography
created_by: mshimoyama
creation_date: 2011-10-04T03:21:14Z

[Term]
id: MMO:0000023
name: electroencephalography (EEG)
def: "A procedure that measures electrical potentials on the scalp generating a record of the electrical activity of the brain." [http://en.wikipedia.org/wiki/ "Wikipedia"]
synonym: "EEG" RELATED []
is_a: MMO:0000001 ! electrical potential recording method

[Term]
id: MMO:0000024
name: ultrasound method
def: "A technique which uses the visualization of deep structures of the body by recording the reflections of pulses of ultrasonic waves directed into the tissues." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000026 ! in vivo method

[Term]
id: MMO:0000025
name: ultrasonic flowmeter with doppler
def: "An ultrasound in which shifts in frequency between emitted ultrasonic waves and their echoes are used to measure the velocities of moving objects, primarily blood flow within vessels." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "doppler shift ultrasonic flow meter" RELATED []
is_a: MMO:0000228 ! ultrasonic flowmeter

[Term]
id: MMO:0000026
name: in vivo method
def: "A procedure or technique performed in or on a living body, for example, a procedure performed on an organ in situ or on the entire living organism, by which a morphological or physiological state or property of that body or body part is assessed and a quantitative or qualitative value assigned." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:22654893]
is_a: MMO:0000000 ! measurement method

[Term]
id: MMO:0000027
name: ex vivo method
def: "A procedure or technique performed outside the living body by which a morphological or physiological state or property in a single sample or a group of samples is assessed and a quantitative or qualitative value assigned." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:22654893]
is_a: MMO:0000000 ! measurement method

[Term]
id: MMO:0000028
name: isolated perfused heart method
def: "In this method, the aorta is cannulated and the heart is perfused in a retrograde fashion." [http://www.adinstruments.com "AD_Instruments"]
synonym: "Langendorf" RELATED []
is_a: MMO:0000082 ! isolated organ perfusion method

[Term]
id: MMO:0000029
name: balloon tipped catheter with pressure transducer in isolated perfused heart
synonym: "Langendorf, balloon tipped catheter" RELATED []
is_a: MMO:0000205 ! balloon tipped catheter in isolated perfused heartr

[Term]
id: MMO:0000030
name: ex vivo blood analysis
def: "Determination of the component parts or elements of blood and their quantity or quality after the blood has been removed from the body. Blood is the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed]
is_a: MMO:0000371 ! ex vivo biological fluid analysis

[Term]
id: MMO:0000031
name: tail cuff plethysmography
is_a: MMO:0000076 ! plethysmography
created_by: mshimoyama
creation_date: 2011-10-04T03:24:59Z

[Term]
id: MMO:0000032
name: automated standard complete blood count (CBC) test
is_a: MMO:0000146 ! automated blood cell counting method

[Term]
id: MMO:0000033
name: arterial puncture
def: "Extraction of blood from an artery using a needle.  In human the brachial and radial arteries are most commonly used." [ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed]
is_a: MMO:0000097 ! blood draw method
created_by: mshimoyama
creation_date: 2010-06-25T11:23:35Z

[Term]
id: MMO:0000034
name: digital rectal thermometry
def: "A method which uses a digital thermometer, an instrument with a defined scale for determining temperature which presents its measurements in the form of discrete numeric symbols, inserted into the rectum of an organism, that is, the  terminal portion of the large intestine, to measure body temperature." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "digital rectal thermometer method" RELATED []
is_a: MMO:0000193 ! in vivo thermometry

[Term]
id: MMO:0000035
name: digital scale
is_obsolete: true
created_by: mshimoyama
creation_date: 2011-10-04T00:00:00Z

[Term]
id: MMO:0000036
name: automated blood gas analysis using a Bayer analyzer
def: "Method for assessing the levels of dissolved gases in blood samples using a Bayer automated gas analyzer, a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "Bayer automated gas analyzer method" RELATED []
is_a: MMO:0000175 ! automated blood gas analysis
created_by: mshimoyama
creation_date: 2011-11-17T09:35:14Z

[Term]
id: MMO:0000037
name: automated blood electrolyte analysis
def: "Automated analysis of one or more electrolytes, substances which dissociate into ions, in the blood." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000179 ! automated blood analysis
created_by: mshimoyama
creation_date: 2010-01-05T03:51:21Z

[Term]
id: MMO:0000038
name: blood lipid analysis
def: "A method to determine the level of one or more lipids, water insoluble fats and fat-like substances, in blood." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000030 ! ex vivo blood analysis
created_by: mshimoyama
creation_date: 2010-01-05T03:51:38Z

[Term]
id: MMO:0000039
name: flame atomic emission spectrometry
def: "A form of atomic spectroscopy in which one observes the emission of light at discrete wavelengths by atoms which have been electronically excited by collisions with other atoms and molecules in a gas or sprayed solution heated in a flame, such as an air/acetylene flame (~2300 degrees C)." [McGraw-Hill:McGraw-Hill_Dictionary_of_Scientific_and_Technical_Terms]
synonym: "atomic flame emission spectroscopy" RELATED []
synonym: "flame emission spectrometry" RELATED []
synonym: "flame photometry" RELATED []
is_a: MMO:0000230 ! atomic emission spectrometry
created_by: mshimoyama
creation_date: 2012-01-09T01:17:42Z

[Term]
id: MMO:0000040
name: dynamometry
def: "A method to measure the degree of force used in the contraction of a group of muscles." [Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "dynamometer method" EXACT []
synonym: "ergometer" RELATED []
is_a: MMO:0000026 ! in vivo method
created_by: mshimoyama
creation_date: 2010-01-05T03:52:16Z

[Term]
id: MMO:0000041
name: 12 lead electrocardiography
def: "Non-invasive procedure for making graphic records of the variations in electrical potential caused by electrical activity of the heart using 3 bipolar limb leads, 3 augmented unipolar limb leads and 6 standard precordial leads. Primarily used with humans." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000003 ! electrocardiography
created_by: mshimoyama
creation_date: 2010-01-05T03:52:49Z

[Term]
id: MMO:0000042
name: CM-5 lead electrocardiography
is_a: MMO:0000003 ! electrocardiography
created_by: mshimoyama
creation_date: 2010-01-05T03:53:04Z

[Term]
id: MMO:0000043
name: oscillometric sphygmomanometer
def: "A method for recording the movements, form and force of the arterial pulse in which the disappearance and reappearance of the pulse are indicated by an oscillating needle." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000201 ! sphygmomanometry
created_by: mshimoyama
creation_date: 2010-01-05T03:55:04Z

[Term]
id: MMO:0000044
name: Colin STBP-780 automated blood pressure monitor
is_a: MMO:0000043 ! oscillometric sphygmomanometer
created_by: mshimoyama
creation_date: 2010-01-05T03:55:21Z

[Term]
id: MMO:0000045
name: large adult cuff Colin STBP-780 automated blood pressure monitor
is_a: MMO:0000044 ! Colin STBP-780 automated blood pressure monitor
created_by: mshimoyama
creation_date: 2010-01-05T03:55:44Z

[Term]
id: MMO:0000046
name: adult cuff Colin STBP-780 automated blood pressure monitor
is_a: MMO:0000044 ! Colin STBP-780 automated blood pressure monitor
created_by: mshimoyama
creation_date: 2010-01-05T03:56:09Z

[Term]
id: MMO:0000047
name: child cuff Colin STBP-780 automated blood pressure monitor
is_a: MMO:0000044 ! Colin STBP-780 automated blood pressure monitor
created_by: mshimoyama
creation_date: 2010-01-05T03:56:37Z

[Term]
id: MMO:0000048
name: Dinamap 1846 SX/P blood pressure monitor
is_a: MMO:0000043 ! oscillometric sphygmomanometer
created_by: mshimoyama
creation_date: 2010-01-05T03:57:09Z

[Term]
id: MMO:0000049
name: large adult cuff Dinamap 1846 SX/P blood pressure monitor
is_a: MMO:0000048 ! Dinamap 1846 SX/P blood pressure monitor
created_by: mshimoyama
creation_date: 2010-01-05T03:57:48Z

[Term]
id: MMO:0000050
name: adult cuff Dinamap 1846 SX/P blood pressure monitor
is_a: MMO:0000048 ! Dinamap 1846 SX/P blood pressure monitor
created_by: mshimoyama
creation_date: 2010-01-05T03:58:13Z

[Term]
id: MMO:0000051
name: child cuff Dinamap 1846 SX/P blood pressure monitor
is_a: MMO:0000048 ! Dinamap 1846 SX/P blood pressure monitor
created_by: mshimoyama
creation_date: 2010-01-05T03:58:44Z

[Term]
id: MMO:0000052
name: tail cuff photoplethysmography
def: "A technique for assessing blood flow by placing a diode that is part of a cuff that is placed on the skin over a blood vessel in the tail of a vertebrate with the amount of light reflected back to the sensor being inversely proportional to the number of red blood cells flowing through the vessel." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000008 ! photoplethysmography
is_a: MMO:0000031 ! tail cuff plethysmography
created_by: mshimoyama
creation_date: 2010-01-05T04:00:14Z

[Term]
id: MMO:0000053
name: tail cuff piezoplethysmography
def: "A technique using piezoelectric crystals with a sensor to assess blood flow by placing it above a blood vessel in the tail of a vertebrate." [Kent:www.kentscientifc.com]
is_a: MMO:0000009 ! piezoplethysmography
is_a: MMO:0000031 ! tail cuff plethysmography
created_by: mshimoyama
creation_date: 2010-01-05T04:00:35Z

[Term]
id: MMO:0000054
name: tail cuff volume pressure recording
is_a: MMO:0000010 ! volume pressure recording
created_by: mshimoyama
creation_date: 2010-01-05T04:01:07Z

[Term]
id: MMO:0000055
name: auscultatory sphygmomanometer
def: "An instrument for indirect measurement of blood pressure consisting of an inflatable cuff that fits around a limb or tail and a bulb for controlling air pressure within the cuff and a mercury or aneroid manometer with assessment based on sounds heard through a stethoscope." [Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000201 ! sphygmomanometry
created_by: mshimoyama
creation_date: 2010-01-05T04:01:42Z

[Term]
id: MMO:0000056
name: large adult cuff auscultatory sphygmomanometer
is_a: MMO:0000055 ! auscultatory sphygmomanometer
created_by: mshimoyama
creation_date: 2010-01-05T04:02:01Z

[Term]
id: MMO:0000057
name: adult cuff auscultatory sphygmomanometer
is_a: MMO:0000055 ! auscultatory sphygmomanometer
created_by: mshimoyama
creation_date: 2010-01-05T04:02:19Z

[Term]
id: MMO:0000058
name: child cuff auscultatory sphygmomanometer
is_a: MMO:0000055 ! auscultatory sphygmomanometer
created_by: mshimoyama
creation_date: 2010-01-05T04:02:36Z

[Term]
id: MMO:0000059
name: small adult cuff Dinamap 1846 SX/P blood pressure monitor
is_a: MMO:0000048 ! Dinamap 1846 SX/P blood pressure monitor
created_by: mshimoyama
creation_date: 2010-03-04T08:26:26Z

[Term]
id: MMO:0000060
name: thigh cuff Dinamap 1846 SX/P blood pressure monitor
is_a: MMO:0000048 ! Dinamap 1846 SX/P blood pressure monitor
created_by: mshimoyama
creation_date: 2010-03-04T08:26:54Z

[Term]
id: MMO:0000061
name: small adult cuff auscultatory sphygmomanometer
is_a: MMO:0000055 ! auscultatory sphygmomanometer
created_by: mshimoyama
creation_date: 2010-03-04T01:36:02Z

[Term]
id: MMO:0000062
name: thigh cuff auscultatory sphygmomanometer
is_a: MMO:0000055 ! auscultatory sphygmomanometer
created_by: mshimoyama
creation_date: 2010-03-04T01:36:40Z

[Term]
id: MMO:0000063
name: random zero sphygmomanometer
is_a: MMO:0000201 ! sphygmomanometry
created_by: mshimoyama
creation_date: 2010-03-04T01:41:21Z

[Term]
id: MMO:0000064
name: Hawksley random zero sphygomomanometer
is_a: MMO:0000063 ! random zero sphygmomanometer
created_by: mshimoyama
creation_date: 2010-03-04T01:41:50Z

[Term]
id: MMO:0000065
name: adult cuff Hawksley random zero sphygomomanometer
is_a: MMO:0000064 ! Hawksley random zero sphygomomanometer
created_by: mshimoyama
creation_date: 2010-03-04T01:42:19Z

[Term]
id: MMO:0000066
name: large adult cuff Hawksley random zero sphygomomanometer
is_a: MMO:0000064 ! Hawksley random zero sphygomomanometer
created_by: mshimoyama
creation_date: 2010-03-04T01:42:41Z

[Term]
id: MMO:0000067
name: child cuff Hawksley random zero sphygomomanometer
is_a: MMO:0000064 ! Hawksley random zero sphygomomanometer
created_by: mshimoyama
creation_date: 2010-03-04T01:43:05Z

[Term]
id: MMO:0000068
name: small adult cuff Hawksley random zero sphygomomanometer
is_a: MMO:0000064 ! Hawksley random zero sphygomomanometer
created_by: mshimoyama
creation_date: 2010-03-04T01:43:28Z

[Term]
id: MMO:0000069
name: thigh cuff Hawksley random zero sphygomomanometer
is_a: MMO:0000064 ! Hawksley random zero sphygomomanometer
created_by: mshimoyama
creation_date: 2010-03-04T01:43:59Z

[Term]
id: MMO:0000070
name: intra-aortic abdominal radiotelemetry
def: "A method which utilizes a  measurement device implanted in the abdominal aorta which transmits radio signals to a recording device." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "intra-aortic abdominal radiotelemetric implant" RELATED []
is_a: MMO:0000577 ! intra-aortic radiotelemetry
created_by: mshimoyama
creation_date: 2010-06-15T10:14:27Z

[Term]
id: MMO:0000071
name: tonometry
def: "Method to measure tension or pressure, often for intraocular pressure." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000026 ! in vivo method
created_by: mshimoyama
creation_date: 2010-06-15T10:22:33Z

[Term]
id: MMO:0000072
name: bioimpedance method
def: "Method which measures the opposition to the flow of an electrical current through a segment of tissue." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000026 ! in vivo method
created_by: mshimoyama
creation_date: 2010-06-15T10:23:06Z

[Term]
id: MMO:0000073
name: radioimmunoassay
def: "An assay that uses competition between radiolabeled and unlabeled substances in an antigen-antibody reaction to determine concentrations of a specific substance." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "RIA" RELATED []
is_a: MMO:0000098 ! immunoassay
is_a: MMO:0000237 ! radioactivity measurement method
created_by: mshimoyama
creation_date: 2010-07-27T03:10:57Z

[Term]
id: MMO:0000074
name: thoracic electrical bioimpedance (TEB)
def: "Method which measures the electrical resistance of the thorax to a high frequency, very low magnitude current." [http://blue.regence.com "Regence"]
synonym: "ICG" RELATED []
synonym: "Impedance cardiography" RELATED []
is_a: MMO:0000072 ! bioimpedance method
is_a: MMO:0000076 ! plethysmography
created_by: mshimoyama
creation_date: 2010-06-15T12:12:45Z

[Term]
id: MMO:0000075
name: enzyme linked immunosorbent assay
def: "An enzyme immunoassay using enzyme labeled immunoreactant (antigen or antibody) and an immunosorbent (antigen or antibody) bound to a solid support." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "ELISA" EXACT []
is_a: MMO:0000713 ! enzyme immunoassay
created_by: mshimoyama
creation_date: 2010-07-27T03:12:27Z

[Term]
id: MMO:0000076
name: plethysmography
def: "A method for measuring and recording changes in the size and volume of organs and parts of the body by measuring changes in their blood volume or air volume." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000026 ! in vivo method
created_by: mshimoyama
creation_date: 2010-06-15T01:30:58Z

[Term]
id: MMO:0000077
name: applanation tonometry
def: "Method that infers intraocular pressure from force needed to flatten a constant area. In opthamology it measures the pressure from force needed to flatten an area of the cornea. In cardiac studies, it measures the changes in the elasticity of arteries." [APC:www.apccardiovascular.co.uk, http://en.wikipedia.org/wiki/ "Wikipedia"]
is_a: MMO:0000071 ! tonometry
created_by: mshimoyama
creation_date: 2010-06-15T01:37:08Z

[Term]
id: MMO:0000078
name: dynamic contour tonometry
def: "A method that uses the principle of contour matching. In opthamology, miniature pressure sensor inside a tonometer tip which rests on the cornea with a constant force. Also used to measure variation in pressure during the cardiac cycle." [http://en.wikipedia.org/wiki/ "Wikipedia"]
is_a: MMO:0000071 ! tonometry
created_by: mshimoyama
creation_date: 2010-06-15T01:37:37Z

[Term]
id: MMO:0000079
name: impression tonometry
def: "Measures the depth of the impression produced by a small plunger carrying a known weight." [http://en.wikipedia.org/wiki/ "Wikipedia"]
is_a: MMO:0000071 ! tonometry
created_by: mshimoyama
creation_date: 2010-06-15T01:38:20Z

[Term]
id: MMO:0000080
name: skin fold caliper method
def: "A fold of skin is pinched raising a double layer of skin and the underlying adipose tissue with a caliper or compass with curved legs applied at right angles to the pinch for a measurement of thickness." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://www.topendsports.com "TopEndSports", ISBN:978-1416049982]
is_a: MMO:0000159 ! in vivo caliper method
created_by: mshimoyama
creation_date: 2010-06-17T12:21:42Z

[Term]
id: MMO:0000081
name: refractometry
def: "Method in which the composition or purity of a solution or other substance (gas, liquid or solid) is measured by computing the refractive index, the ratio of the speed of light in a vacuum relative to that speed through a given medium." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, Encarta:Encarta_World_English_Dictionary, ISBN:978-1416049982, RGD:MS]
is_a: MMO:0000027 ! ex vivo method
created_by: mshimoyama
creation_date: 2010-06-17T12:27:53Z

[Term]
id: MMO:0000082
name: isolated organ perfusion method
is_a: MMO:0000004 ! isolated body part method
created_by: mshimoyama
creation_date: 2010-06-23T08:33:49Z

[Term]
id: MMO:0000083
name: isolated perfused lung method
def: "The lung is placed in an artificial thoracic chamber and ventilated at negative pressure.  It is connected through a tracheal cannula to a pneumotachometer for measurement of respiratory flow." [http://www.harvardapparatus.com "Harvard_Apparatus"]
is_a: MMO:0000082 ! isolated organ perfusion method
created_by: mshimoyama
creation_date: 2010-06-23T08:35:43Z

[Term]
id: MMO:0000084
name: isolated perfused liver method
is_a: MMO:0000082 ! isolated organ perfusion method
created_by: mshimoyama
creation_date: 2010-06-23T08:44:58Z

[Term]
id: MMO:0000085
name: isolated perfused kidney method
is_a: MMO:0000082 ! isolated organ perfusion method
created_by: mshimoyama
creation_date: 2010-06-23T08:45:20Z

[Term]
id: MMO:0000086
name: balance beam platform medical scale
is_a: MMO:0000217 ! scale
created_by: mshimoyama
creation_date: 2010-06-23T09:22:23Z

[Term]
id: MMO:0000087
name: sliding weight scale
is_a: MMO:0000217 ! scale
created_by: mshimoyama
creation_date: 2010-06-23T09:23:25Z

[Term]
id: MMO:0000088
name: digital column scale
def: "A digital scale, that is, one which uses one or more load cells with a strain gauge to quantify the weight or mass of the object being measured, made up of a platform at floor level with an electronic display mounted on a column or pedestal." [http://www.livestrong.com "Website", RGD:JRS]
is_a: MMO:0000017 ! whole body digital scale
created_by: mshimoyama
creation_date: 2010-06-23T09:23:42Z

[Term]
id: MMO:0000089
name: height scale
is_a: MMO:0000119 ! body measuring method
created_by: mshimoyama
creation_date: 2010-06-23T09:26:22Z

[Term]
id: MMO:0000090
name: venipuncture
def: "Extraction of blood from a vein using a needle. In human, the basilic, cephalic and median cubital veins are most commonly used as well as the femoral vein." [ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed]
is_a: MMO:0000097 ! blood draw method
created_by: mshimoyama
creation_date: 2010-06-25T11:23:47Z

[Term]
id: MMO:0000091
name: hydrostatic weighing method
def: "A method in which the subject's weight is measured in air and underwater to determine density of the body and from that calculate percentage body fat. In general the subject sits in a specialized weighing chair and is lowered into a tank of water after expelling all air from the lungs and once all body parts are submerged, the weight is taken. The general formula is the density of the body divided by the density of the water is equal to the weight of the body in air divided by the weight of the body in air minus the weight of the immersed body." [http://en.wikipedia.org/wiki/Hydrostatic_weighing "Wikipedia"]
is_a: MMO:0000016 ! body weighing method
created_by: mshimoyama
creation_date: 2010-06-23T09:55:48Z

[Term]
id: MMO:0000092
name: ultrasonic flowmeter with pulsed wave doppler
def: "Doppler ultrasonography in which a single trnasducer alternately transmits and records ultrasonic waves, primarily used to assess blood flow within vessels." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000025 ! ultrasonic flowmeter with doppler
created_by: mshimoyama
creation_date: 2010-07-27T03:40:43Z

[Term]
id: MMO:0000093
name: skin puncture
def: "Extraction of blood from skin. In human, fingertips, earlobes and heels are common sites." [ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed]
synonym: "capillary puncture" RELATED []
is_a: MMO:0000097 ! blood draw method
created_by: mshimoyama
creation_date: 2010-06-25T11:24:00Z

[Term]
id: MMO:0000094
name: spirometry
def: "Use of a precision differential pressure transducer for measuring the volume of air inspired and expired by the lungs." [http://en.wikipedia.org/wiki/ "Wikipedia"]
is_a: MMO:0000026 ! in vivo method
created_by: mshimoyama
creation_date: 2010-06-23T10:42:40Z

[Term]
id: MMO:0000095
name: hand dynamometry
def: "A method to measure the degree of force used in the contraction of the muscles of the hand, the distal part of the upper limb, consisting of the carpus, metacarpus, and fingers." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "hand dynamometer method" EXACT []
synonym: "squeeze dynamometer method" RELATED []
is_a: MMO:0000040 ! dynamometry
created_by: mshimoyama
creation_date: 2010-06-23T10:47:36Z

[Term]
id: MMO:0000096
name: stationary bicycle dynamometry
def: "Method which employs a fixed cycling machine (that is, an apparatus having a seat, handlebars, and pedals but which does not move from place to place) to estimate the exercise intensity, work or power output of the participant using the device's revolutions per minute and resistance to pedalling, which can be adjusted to vary the intensity." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Churchill_Livingstone:Dictionary_of_Sport_and_Exercise_Science_and_Medicine_2008]
synonym: "bicycle ergometer method" RELATED []
synonym: "cycloergometer method" RELATED []
synonym: "stationary bicycle dynamometer method" EXACT []
is_a: MMO:0000040 ! dynamometry
created_by: mshimoyama
creation_date: 2010-06-23T10:50:47Z

[Term]
id: MMO:0000097
name: blood draw method
def: "Method for withdrawing blood from an organism." [RGD:MS]
is_a: MMO:0000235 ! body fluid collection method
created_by: mshimoyama
creation_date: 2010-06-25T11:22:39Z

[Term]
id: MMO:0000098
name: immunoassay
def: "A method for  quantitative determination of chemical substances using specific binding between antigen or hapten and homologous antibodies." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000027 ! ex vivo method
created_by: mshimoyama
creation_date: 2010-06-25T12:09:56Z

[Term]
id: MMO:0000099
name: thrombelastometry
def: "Method in which a pin is suspended in a blood sample and oscillates, creating a signal transmitted through an optical detector system which graphs changes in elasticity during the development and resolution of a blood clot." [http://en.wikipedia.org/wiki/Thromboelastometry "Wikipedia"]
synonym: "rotational thrombelastography" RELATED []
synonym: "TEM" RELATED []
is_a: MMO:0000030 ! ex vivo blood analysis
created_by: mshimoyama
creation_date: 2010-06-25T12:49:15Z

[Term]
id: MMO:0000100
name: gel electrophoresis
def: "Separation of ionic solutes based on differences in rate of migration in an applied electric field using a semisolid colloid such as agarose or acrylamide as the support medium." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000287 ! electrophoresis
created_by: mshimoyama
creation_date: 2010-06-25T01:04:03Z

[Term]
id: MMO:0000101
name: pan type baby weighing scale
is_a: MMO:0000218 ! baby weighing scale
created_by: mshimoyama
creation_date: 2010-06-25T02:01:54Z

[Term]
id: MMO:0000102
name: spring type baby weighing scale
is_a: MMO:0000218 ! baby weighing scale
created_by: mshimoyama
creation_date: 2010-06-25T02:02:24Z

[Term]
id: MMO:0000103
name: beam type baby weighing scale
is_a: MMO:0000218 ! baby weighing scale
created_by: mshimoyama
creation_date: 2010-06-25T02:02:39Z

[Term]
id: MMO:0000104
name: digital stadiometer
def: "A device for measuring height with a digital readout." [RGD:MS]
is_a: MMO:0000089 ! height scale
created_by: mshimoyama
creation_date: 2010-06-25T02:05:53Z

[Term]
id: MMO:0000105
name: mechanical stadiometer
def: "A device for measuring height consisting of a vertical ruler with sliding horizontal rod." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed]
is_a: MMO:0000089 ! height scale
created_by: mshimoyama
creation_date: 2010-06-25T02:06:54Z

[Term]
id: MMO:0000106
name: ultrasonic flowmeter with continuous wave doppler
def: "Doppler ultrasonography using two transducers, with one continually transmitting and the other continually recording the ultrasonic waves, primarily used to assess blood flow within vessels." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000025 ! ultrasonic flowmeter with doppler
created_by: mshimoyama
creation_date: 2010-07-27T03:41:02Z

[Term]
id: MMO:0000107
name: HP Sonos 5500 echo ultrasound
is_a: MMO:0000002 ! transthoracic echocardiography
created_by: mshimoyama
creation_date: 2010-07-27T04:03:03Z

[Term]
id: MMO:0000108
name: transesophageal echocardiography
def: "Echocardiography in which an ultrasound transducer attached to a fiberoptic endoscope is inserted into the esophagus to provide two dimensional images of the heart." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "TEE" RELATED []
synonym: "TOE" RELATED []
synonym: "transaesophageal echocardiography" EXACT []
is_a: MMO:0000337 ! echocardiography
created_by: mshimoyama
creation_date: 2010-07-27T04:05:57Z

[Term]
id: MMO:0000109
name: ex vivo microscopy
def: "Examination or observation of material performed outside the living body using a microscope, an instrument used to obtain an enlarged image of small objects and reveal details of structure not otherwise distinguishable." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000027 ! ex vivo method
created_by: mshimoyama
creation_date: 2010-07-27T04:26:49Z

[Term]
id: MMO:0000110
name: ex vivo electron microscopy
def: "Examination or observation of material performed outside the living body through a microscope using beams of electrons, negatively charged elementary particles, to produce magnified images. A microscope is an instrument used to obtain an enlarged image of small objects and reveal details of structure not otherwise distinguishable." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://www.answers.com/ "Website", ISBN:978-1416049982]
is_a: MMO:0000109 ! ex vivo microscopy
created_by: mshimoyama
creation_date: 2010-07-27T04:28:48Z

[Term]
id: MMO:0000111
name: ex vivo light microscopy
def: "Examination or observation of material performed outside the living body through a light microscope, an optical instrument that uses visible light (electromagnetic radiation with wavelengths between approximately 390 and 700 nm) processed through a lens or a combination of lenses to produce magnified images." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Visible_spectrum "Wikipedia", http://www.answers.com/ "Website", ISBN:978-1416049982]
is_a: MMO:0000109 ! ex vivo microscopy
created_by: mshimoyama
creation_date: 2010-07-27T04:33:09Z

[Term]
id: MMO:0000112
name: blood glucose analysis
def: "A method to determine the level of glucose, the end product of carbohydrate metabolism, in the blood." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000705 ! blood carbohydrates and carbohydrate derivative analysis
created_by: mshimoyama
creation_date: 2010-08-05T01:55:51Z

[Term]
id: MMO:0000113
name: oral glucose tolerance test
def: "A test in which glucose is given orally, often in solution, and blood samples taken afterward at specific time interval(s) to determine how quickly it is cleared from the blood." [http://en.wikipedia.org/wiki/ "Wikipedia"]
synonym: "OGTT" EXACT []
is_a: MMO:0000204 ! glucose tolerance analysis
created_by: mshimoyama
creation_date: 2010-08-05T01:56:02Z

[Term]
id: MMO:0000114
name: isolated perfused heart effluent collection
def: "Collection of the fluid flowing out of the heart during the Langendorff isolated perfused heart method." [PGA:Cardiac_protocol]
synonym: "Langendorff heart effluent collection" EXACT []
is_a: MMO:0000028 ! isolated perfused heart method
created_by: JSmith
creation_date: 2012-02-16T12:16:06Z

[Term]
id: MMO:0000115
name: random blood glucose test (RBG)
def: "Measures blood glucose level one or more times a day regardless of food intake." [ISBN:978-0071623803, Keogh:Nursing_Laboratory_and_Diagnostic_Tests_Demystified]
synonym: "non-fasting blood glucose test" RELATED []
is_a: MMO:0000112 ! blood glucose analysis
created_by: mshimoyama
creation_date: 2010-08-05T02:00:39Z

[Term]
id: MMO:0000116
name: Health-O-Meter balance beam Scale
is_a: MMO:0000086 ! balance beam platform medical scale
created_by: mshimoyama
creation_date: 2010-08-05T02:04:58Z

[Term]
id: MMO:0000117
name: Detecto balance beam scale
is_a: MMO:0000086 ! balance beam platform medical scale
created_by: mshimoyama
creation_date: 2010-08-05T02:07:21Z

[Term]
id: MMO:0000118
name: Harpenden skin fold caliper
def: "A caliper with a dial gauge for measuring skin folds or girth measurements of small joints manufactured by Baty." [http://www.skinfold-caliper.com/ "Harpenden"]
is_a: MMO:0000191 ! dial skin fold caliper method
created_by: mshimoyama
creation_date: 2010-08-05T02:08:15Z

[Term]
id: MMO:0000119
name: body measuring method
def: "A procedure to measure a morphological parameter of all or part of the body of an organism." [RGD:JRS]
is_a: MMO:0000026 ! in vivo method
created_by: mshimoyama
creation_date: 2010-08-05T02:08:38Z

[Term]
id: MMO:0000120
name: anthropometric tape
def: "A tape of cloth, paper, metal or other materials marked off in a linear scale for taking measurements." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed]
is_a: MMO:0000119 ! body measuring method
created_by: mshimoyama
creation_date: 2010-08-05T02:09:03Z

[Term]
id: MMO:0000121
name: Grafco fiberglass anthropometric tape
is_a: MMO:0000120 ! anthropometric tape
created_by: mshimoyama
creation_date: 2010-08-05T02:09:22Z

[Term]
id: MMO:0000122
name: Lange skin fold caliper
def: "A caliper with a dial for measuring the thickness of skin folds, manufactured by Beta." [Beta:www.beta-technology.com]
is_a: MMO:0000191 ! dial skin fold caliper method
created_by: mshimoyama
creation_date: 2010-08-05T02:10:07Z

[Term]
id: MMO:0000123
name: Lafayette small anthropometer method
def: "A body measuring method which employs a Lafayette small anthropometer, an instrument for measuring dimensions of a body often consisting of a calibrated, vertical rod to which one fixed and one movable horizontal arms are attached." [http://dictionary.infoplease.com "Infoplease"]
is_a: MMO:0000119 ! body measuring method
created_by: mshimoyama
creation_date: 2010-08-05T02:11:34Z

[Term]
id: MMO:0000124
name: in vivo radiography
def: "Using X-rays or gamma rays to create records of the internal structures of a living body." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000026 ! in vivo method
created_by: mshimoyama
creation_date: 2010-08-05T02:16:01Z

[Term]
id: MMO:0000125
name: serial radiography
def: "Radiographic method involving multiple records of selected area at intervals." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000124 ! in vivo radiography
created_by: mshimoyama
creation_date: 2010-08-05T02:16:57Z

[Term]
id: MMO:0000126
name: electron radiography
def: "Technique in which a latent electron image is produce on clear plastic by passing X-ray photons through a gas with a high atomic number." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000124 ! in vivo radiography
created_by: mshimoyama
creation_date: 2010-08-05T02:18:57Z

[Term]
id: MMO:0000127
name: tomography
def: "Recording of internal body images at a predetermined plane using an apparatus for moving an X-ray source in one direction as the film is moved in the opposite direction." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000124 ! in vivo radiography
created_by: mshimoyama
creation_date: 2010-08-05T02:20:57Z

[Term]
id: MMO:0000128
name: computed tomography
def: "Tomography, that is, method that produces images of single tissue planes, in which the emergent X-ray beam is measured by a scintillation counter and the electronic impulses are recorded on a magnetic disk and processed by a mini-computer for reconstruction display of the body in cross-section on a cathode ray tube." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed]
synonym: "CAT scan" RELATED []
synonym: "computed axial tomography" RELATED []
synonym: "computerized axial tomography (CAT)" RELATED []
synonym: "CT scan" RELATED []
synonym: "X-ray computed tomography" RELATED []
is_a: MMO:0000127 ! tomography
created_by: mshimoyama
creation_date: 2010-08-05T02:24:12Z

[Term]
id: MMO:0000129
name: positron emission tomography (PET)
def: "Detection of gamma rays emitted from tissues after administration of natural biochemical substance into which positron emitting isotopes have been incorporated. The paths of the gamma rays resulting from collision of positrons and electrons are interpreted by a computer to form a representation of local concentrations of the isotope-containing substance." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "PET scan" RELATED []
is_a: MMO:0000127 ! tomography
created_by: mshimoyama
creation_date: 2010-08-05T02:27:10Z

[Term]
id: MMO:0000130
name: air displacement plethysmography
def: "A method for measuring body composition/density, for instance using a fiberglass chamber incorporating an electronic scale and air volume measurement device to record air volume when the chamber is empty and when an individual is inside." [http://www.bodpod.com "Life_Measurement"]
synonym: "ADP" RELATED []
synonym: "BodPod" RELATED []
synonym: "PEA POD" RELATED []
synonym: "whole-body air displacement plethysmography" RELATED []
is_a: MMO:0000076 ! plethysmography
created_by: mshimoyama
creation_date: 2010-08-05T02:31:44Z

[Term]
id: MMO:0000131
name: Seritex stadiometer
is_a: MMO:0000105 ! mechanical stadiometer
created_by: mshimoyama
creation_date: 2010-08-05T02:35:08Z

[Term]
id: MMO:0000132
name: serum total cholesterol measurement test
def: "A test which determines total amount of cholesterol carried in high-density lipoprotein (HDL), low-density lipoprotein (LDL) and very-low-density lipoprotein (VLDL) molecules in a volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [CMDT:Current_Medical_Diagnosis_and_Treatment--42nd_Ed, ISBN:978-0071395939, ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed, RGD:SL]
is_a: MMO:0000280 ! blood total cholesterol measurement test
created_by: mshimoyama
creation_date: 2010-09-01T08:35:54Z

[Term]
id: MMO:0000133
name: serum high-density lipoprotein-cholesterol measurement test
def: "A test which determines the amount of cholesterol carried in high-density lipoprotein (HDL) particles in a sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [CMDT:Current_Medical_Diagnosis_and_Treatment--42nd_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-0071395939, ISBN:978-1416049982]
synonym: "serum HDL-cholesterol test" RELATED []
is_a: MMO:0000278 ! blood high-density lipoprotein-cholesterol measurement test
created_by: mshimoyama
creation_date: 2010-09-01T08:42:25Z

[Term]
id: MMO:0000134
name: serum low-density lipoprotein-cholesterol measurement test
def: "A test which determines the amount of cholesterol carried in low-density lipoprotein (LDL) particles in serum, the clear liquid that separates from blood after it has clotted completely." [CMDT:Current_Medical_Diagnosis_and_Treatment--42nd_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-0071395939, ISBN:978-1416049982]
synonym: "serum LDL-cholesterol test" RELATED []
is_a: MMO:0000279 ! blood low-density lipoprotein-cholesterol measurement test
created_by: mshimoyama
creation_date: 2010-09-01T09:08:58Z

[Term]
id: MMO:0000135
name: serum very low-density lipoprotein-cholesterol measurement test
def: "A test which determines the amount of cholesterol carried in very-low-density lipoprotein (VLDL) particles serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [CMDT:Current_Medical_Diagnosis_and_Treatment--42nd_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-0071395939, ISBN:978-1416049982]
synonym: "VLDL-cholesterol test" RELATED []
is_a: MMO:0000281 ! blood very low-density lipoprotein-cholesterol measurement test
created_by: mshimoyama
creation_date: 2010-09-01T09:09:19Z

[Term]
id: MMO:0000136
name: serum triglyceride analysis
def: "A laboratory test which measures the level of triglyceride, the naturally occurring ester of three fatty acids and glycerol that is the chief constituent of fat, in serum.  Serum is the clear liquid that separates from blood when it is allowed to clot completely, and is therefore blood plasma from which fibrinogen has been removed during clotting." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "serum triglyceride measurement test" RELATED []
is_a: MMO:0000233 ! blood triglyceride analysis
created_by: mshimoyama
creation_date: 2010-09-01T09:10:19Z

[Term]
id: MMO:0000137
name: automated serum ionized calcium test
def: "Automated determination of the level of ionized (free) calcium in serum." [https://pediaa.com/what-is-the-difference-between-ionized-calcium-and-serum-calcium/]
synonym: "automated test of free calcium in serum" EXACT []
is_a: MMO:0000784 ! automated serum calcium test
created_by: mshimoyama
creation_date: 2010-09-01T09:13:33Z

[Term]
id: MMO:0000138
name: automated serum non-ionized calcium test
def: "This is the automated analysis of calcium in blood serum that is bound to anions and proteins" [https://pediaa.com/what-is-the-difference-between-ionized-calcium-and-serum-calcium/]
synonym: "automated  test of bound calcium in serum" EXACT []
is_a: MMO:0000784 ! automated serum calcium test
created_by: mshimoyama
creation_date: 2010-09-01T09:13:53Z

[Term]
id: MMO:0000139
name: automated serum magnesium test
is_a: MMO:0000556 ! automated serum electrolyte analysis
created_by: mshimoyama
creation_date: 2010-09-01T09:14:47Z

[Term]
id: MMO:0000140
name: automated serum phosphate test
is_a: MMO:0000556 ! automated serum electrolyte analysis
created_by: mshimoyama
creation_date: 2010-09-01T09:15:50Z

[Term]
id: MMO:0000141
name: automated serum potassium test
def: "Automated analysis to determine the level of potassium ions in serum." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000556 ! automated serum electrolyte analysis
created_by: mshimoyama
creation_date: 2010-09-01T09:16:34Z

[Term]
id: MMO:0000142
name: automated serum sodium test
def: "Automated analysis to determine the level of sodium ions in serum." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000556 ! automated serum electrolyte analysis
created_by: mshimoyama
creation_date: 2010-09-01T09:17:26Z

[Term]
id: MMO:0000143
name: automated serum chloride test
def: "An automated analysis to determine the level of chloride ions in serum." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000556 ! automated serum electrolyte analysis
created_by: mshimoyama
creation_date: 2010-09-01T09:17:36Z

[Term]
id: MMO:0000144
name: automated total white blood cell count test
is_a: MMO:0000146 ! automated blood cell counting method
created_by: mshimoyama
creation_date: 2010-09-01T09:32:59Z

[Term]
id: MMO:0000145
name: automated differential white blood cell count test
is_a: MMO:0000146 ! automated blood cell counting method
created_by: mshimoyama
creation_date: 2010-09-01T09:33:13Z

[Term]
id: MMO:0000146
name: automated blood cell counting method
def: "Use of an automated analyzer for the examination of one or more of the cell types in blood to determine quantitative  properties." [ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed]
synonym: "automated hemocytometer" RELATED []
is_a: MMO:0000174 ! automated hematology analysis
is_a: MMO:0000445 ! blood cell counting method
created_by: mshimoyama
creation_date: 2010-09-01T09:38:02Z

[Term]
id: MMO:0000147
name: urine analysis
def: "Any method to determine the nature, properties, or composition of urine, the fluid waste product excreted by the kidneys, including measurement of the volume of urine or of the quantity or quality of component parts of urine." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "urinalysis" RELATED []
is_a: MMO:0000371 ! ex vivo biological fluid analysis
created_by: mshimoyama
creation_date: 2010-09-01T09:58:30Z

[Term]
id: MMO:0000148
name: manually read urine amylase test strip
def: "A reagent test strip which measures the quantity of amylase, an enzyme produced primarily in the pancreas, in urine and visually matched against a score chart." [ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed]
is_a: MMO:0000181 ! manually read urine test strip
created_by: mshimoyama
creation_date: 2010-09-01T09:59:53Z

[Term]
id: MMO:0000149
name: manually read urine cortisol test strip
def: "A reagent test strip which measures the amount of cortisol, the major natural glucocorticoid synthesized in the adrenal cortex, in urine and visually matched against a score chart." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000181 ! manually read urine test strip
created_by: mshimoyama
creation_date: 2010-09-01T10:00:19Z

[Term]
id: MMO:0000150
name: manually read urine glucose test strip
def: "A reagent strip that measures the amount of glucose in urine and visually matched against a score chart." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000181 ! manually read urine test strip
created_by: mshimoyama
creation_date: 2010-09-01T10:00:57Z

[Term]
id: MMO:0000151
name: manually read urine microalbumin test strip
def: "A solid phase colorimetric assay to detect very low levels of albumin, the major blood plasma protein which is responsible for much of the plasma colloidal osmotic pressure and serves as a transport protein for large organic anions such as fatty acids and bilirubin, in a specified sample of urine, in which a strip of paper, or of plastic with one or more attached pads of paper, impregnated with a reagent that reacts with albumin is dipped into the urine sample, allowed to react for a specified period of time and then the results are assessed by a visual comparison with a standard chromatic/color scale." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-0323057479, ISBN:978-1416049982, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed]
is_a: MMO:0000181 ! manually read urine test strip
is_a: MMO:0000336 ! urine microalbumin analysis
created_by: mshimoyama
creation_date: 2010-09-01T10:01:23Z

[Term]
id: MMO:0000152
name: isolated perfused lung vascular effluent collection
is_a: MMO:0000083 ! isolated perfused lung method
created_by: JSmith
creation_date: 2012-03-15T01:42:06Z

[Term]
id: MMO:0000153
name: manually read urine potassium test strip
def: "A solid phase colorimetric assay utilizing a strip of paper, or of plastic with one or more attached pads of paper, impregnated with a reagent that specifically reacts with potassium ions. The strip is dipped into the urine sample, allowed to react for a specified period of time and the results assessed by a visual comparison with a standard chromatic/color scale." [Collins:Collins_Online_English_Dictionary, http://en.wikipedia.org/wiki/Urine_test_strip "Wikipedia"]
synonym: "manually read urine K+ test strip" RELATED []
is_a: MMO:0000181 ! manually read urine test strip
is_a: MMO:0000463 ! urine potassium test strip
created_by: mshimoyama
creation_date: 2010-09-01T10:02:43Z

[Term]
id: MMO:0000154
name: manually read urine sodium test strip
def: "A solid phase colorimetric assay utilizing a strip of paper, or of plastic with one or more attached pads of paper, impregnated with a reagent that specifically reacts with sodium ions. The strip is dipped into the urine sample, allowed to react for a specified period of time and the results assessed by a visual comparison with a standard chromatic/color scale." [Collins:Collins_Online_English_Dictionary, http://en.wikipedia.org/wiki/Urine_test_strip "Wikipedia"]
synonym: "manually read urine Na+ test strip" RELATED []
is_a: MMO:0000181 ! manually read urine test strip
is_a: MMO:0000464 ! urine sodium test strip
created_by: mshimoyama
creation_date: 2010-09-01T10:03:07Z

[Term]
id: MMO:0000155
name: blood uric acid analysis
is_a: MMO:0000030 ! ex vivo blood analysis
created_by: mshimoyama
creation_date: 2010-09-01T10:03:46Z

[Term]
id: MMO:0000156
name: manually read urine uric acid test strip
def: "A reagent strip that measures the amount of uric acid, the end product of purine catabolism, in urine and visually matched against a score chart." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000181 ! manually read urine test strip
created_by: mshimoyama
creation_date: 2010-09-01T10:05:52Z

[Term]
id: MMO:0000157
name: digital scale post excision weight measurement
def: "Use of a digital scale--i.e. one using alphanumeric characters as opposed to the relative position of needles or 'hands' (as with a clock) against a background scale to display data--for measuring the weight of an organ, tissue or other body part after it has been removed from the body. The weight of an object is its heaviness, that is, the force exerted on it by gravitational force which is proportional to its mass." [Mosby:Mosbys_Dental_Dictionary--2nd_Ed]
is_a: MMO:0000005 ! post excision weight measurement
created_by: mshimoyama
creation_date: 2010-10-08T02:08:28Z

[Term]
id: MMO:0000158
name: manual palpation method
is_a: MMO:0000026 ! in vivo method
created_by: mshimoyama
creation_date: 2010-11-01T11:21:03Z

[Term]
id: MMO:0000159
name: in vivo caliper method
def: "A procedure or technique performed in or on a living body, for example, a procedure performed on an organ in situ or on the entire living organism, to measure the thickness or diameter of a solid using a compass with bent or curved legs or a device comprised of a calibrated scale with a fixed jaw, and another jaw, with a pointer, that slides along the scale from which the distance between the two pieces can be read." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Caliper "Wikipedia", ISBN:978-1416049982]
is_a: MMO:0000492 ! in vivo linear measurement method
created_by: mshimoyama
creation_date: 2010-11-01T11:22:45Z

[Term]
id: MMO:0000160
name: unspecified method
def: "Method was not specified in source of data." [RGD:MS]
is_a: MMO:0000000 ! measurement method
created_by: mshimoyama
creation_date: 2010-11-01T11:26:15Z

[Term]
id: MMO:0000161
name: isolated tissue method
def: "Any method which a measurement is made of a morphological or physiological characteristic of a tissue, that is, an aggregation of similarly specialized cells united in the performance of a particular function, after that tissue has been removed from the body." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000004 ! isolated body part method
created_by: mshimoyama
creation_date: 2010-11-01T12:38:01Z

[Term]
id: MMO:0000162
name: ex vivo visual assessment
def: "A procedure or technique performed on a tissue or body part outside of or away from the living organism but while the tissue itself remains viable, by which a morphological or physiological state or property of that tissue or body part is evaluated, appraised or perceived through the sense of sight, rather than through the use of instruments or machines to make measurements." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, Farlex:Farlex_Partner_Medical_Dictionary_2012, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed, PMID:22654893]
comment: For observations of living organisms as a whole, or of organs or tissues in situ (that is, operating normally within the living body), use the term "in vivo visual assessment".
is_a: MMO:0000027 ! ex vivo method
created_by: mshimoyama
creation_date: 2010-11-01T12:39:05Z

[Term]
id: MMO:0000163
name: in vivo visual assessment
def: "A procedure or technique performed in or on a living body, for example, a procedure performed on an organ in situ or on the entire living organism, by which a morphological or physiological state or property of that body or body part is evaluated, appraised or perceived through the sense of sight, rather than through the use of instruments or machines to make measurements." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed, PMID:22654893]
is_a: MMO:0000026 ! in vivo method
created_by: mshimoyama
creation_date: 2010-11-01T12:39:26Z

[Term]
id: MMO:0000164
name: intraperitoneal glucose tolerance test
def: "A test in which glucose is injected into the peritoneal cavity and blood samples taken afterward at specified interval(s) to determine how quickly it is cleared from the blood." [http://en.wikipedia.org/wiki/ "Wikipedia"]
synonym: "IPGTT" EXACT []
is_a: MMO:0000204 ! glucose tolerance analysis
created_by: mshimoyama
creation_date: 2010-11-08T09:32:54Z

[Term]
id: MMO:0000165
name: blood glucose test strip read by electrochemical glucometer
def: "This is an automated device that calculates glucose levels in blood from a very small sample (~1 ul) on an electrochemical test strip. The glucose-derived electrons from the sample are routed directly through the external meter and counted so a glucose level may be automatically calculated." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, https://knowledge.electrochem.org/encycl/art-g01-glucose.htm]
synonym: "blood glucose test strip read by electro-chemical glucometer" EXACT []
synonym: "EBGTS" EXACT []
synonym: "electrochemical blood glucose test strip" EXACT []
xref: https://knowledge.electrochem.org/encycl/art-g01-glucose.htm
is_a: MMO:0000190 ! machine read blood glucose test strip
created_by: mshimoyama
creation_date: 2010-11-10T02:37:57Z

[Term]
id: MMO:0000166
name: blood protein analysis
def: "A method to determine the level of one or more proteins, Any of a group of complex organic compounds containing carbon, hydrogen, oxygen, nitrogen, and sulfur consisting of alpha-amino acids joined by peptide linkages, in blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed]
is_a: MMO:0000030 ! ex vivo blood analysis
created_by: mshimoyama
creation_date: 2010-11-12T09:50:34Z

[Term]
id: MMO:0000167
name: blood lipoprotein analysis
def: "A test which measures one or more properties such as the amount, composition, etc of lipoprotein or a component of lipoprotein in blood. A lipoprotein is any of a group of conjugated proteins that have at least one lipid component and are the principal means by which lipids are transported in the blood." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007]
synonym: "blood lipoprotein test" RELATED []
is_a: MMO:0000038 ! blood lipid analysis
is_a: MMO:0000166 ! blood protein analysis
created_by: mshimoyama
creation_date: 2010-11-12T09:51:09Z

[Term]
id: MMO:0000168
name: automated blood creatinine analysis
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the level of creatinine, the catabolic product of creatine, in blood." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000179 ! automated blood analysis
is_a: MMO:0000270 ! blood creatinine analysis
created_by: mshimoyama
creation_date: 2010-11-15T08:10:07Z

[Term]
id: MMO:0000169
name: standard blood chemistry panel
def: "A standardized group of blood tests which are routinely performed to determine the general health of a patient or test subject." [https://labtestsonline.org/tests/chemistry-panels "Website"]
is_a: MMO:0000030 ! ex vivo blood analysis
created_by: mshimoyama
creation_date: 2010-11-15T08:32:38Z

[Term]
id: MMO:0000170
name: osmometry
def: "Method for measuring the osmolality or concentration of particles in a solution." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000027 ! ex vivo method
created_by: mshimoyama
creation_date: 2011-01-31T03:41:08Z

[Term]
id: MMO:0000171
name: urine test strip
def: "A solid phase colorimetric assay utilizing a strip of paper, or of plastic with one or more attached pads of paper, impregnated with a reagent that reacts with an element or compound is dipped into the urine sample, allowed to react for a specified period of time and the results then assessed by a visual comparison with a standard chromatic/color scale or by an automated analyzer." [Collins:Collins_Online_English_Dictionary, http://en.wikipedia.org/wiki/Urine_test_strip "Wikipedia"]
synonym: "urine dipstick test" RELATED []
is_a: MMO:0000147 ! urine analysis
is_a: MMO:0000328 ! solid phase colorimetry
created_by: mshimoyama
creation_date: 2011-01-31T03:47:01Z

[Term]
id: MMO:0000172
name: spectrometry
def: "A method in which an emission (as of particles or radiation) is dispersed according to some property (as mass or energy) of the emission and the amount of dispersion is measured." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed]
is_a: MMO:0000027 ! ex vivo method
created_by: mshimoyama
creation_date: 2011-01-31T04:01:15Z

[Term]
id: MMO:0000173
name: spectrophotometry
def: "A method to evaluate a chemical substance for a molecule of interest, based on the molecule's ability to alter the transmittance or reflectance of solutions, transparent or opaque solids, such as polished glass, or gases." [https://en.wikipedia.org/wiki/Spectrophotometry "Wikipedia", McGraw-Hill:McGraw-Hill_Concise_Dictionary_of_Modern_Medicine, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000172 ! spectrometry
created_by: mshimoyama
creation_date: 2011-01-31T04:03:07Z

[Term]
id: MMO:0000174
name: automated hematology analysis
def: "An automated device used to analyze the physical or chemical characteristics of a sample of blood." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000179 ! automated blood analysis
created_by: mshimoyama
creation_date: 2011-02-01T08:09:57Z

[Term]
id: MMO:0000175
name: automated blood gas analysis
def: "Analysis using an automated device for measuring levels of oxygen, carbon dioxide, carbon monoxide and nitrogen in blood." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000179 ! automated blood analysis
created_by: mshimoyama
creation_date: 2011-02-01T08:15:28Z

[Term]
id: MMO:0000176
name: manually read blood glucose test strip
def: "A test strip or dipstick which contains a reagent that reacts with glucose in blood and which is manually read." [ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed]
is_a: MMO:0000189 ! blood glucose test strip
created_by: mshimoyama
creation_date: 2011-02-01T08:31:53Z

[Term]
id: MMO:0000177
name: automated urine analysis
def: "Use of an automated device for measuring the physical and chemical characteristics of urine." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000147 ! urine analysis
created_by: mshimoyama
creation_date: 2011-02-01T08:34:34Z

[Term]
id: MMO:0000178
name: automated coagulometer method
def: "An automated method using a device that measures the ability of blood to clot by performing any of several tests." [http://en.wikipedia.org/wiki/ "Wikipedia"]
is_a: MMO:0000174 ! automated hematology analysis
created_by: mshimoyama
creation_date: 2011-02-01T08:43:39Z

[Term]
id: MMO:0000179
name: automated blood analysis
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the physical or chemical characteristics of blood." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000030 ! ex vivo blood analysis
created_by: mshimoyama
creation_date: 2011-02-01T09:02:57Z

[Term]
id: MMO:0000180
name: machine read urine test strip
def: "A solid phase colorimetric assay utilizing a strip of paper, or of plastic with one or more attached pads of paper, impregnated with a reagent that reacts with an element or compound is dipped into the urine sample, allowed to react for a specified period of time and the results then assessed by an automated analyzer." [Collins:Collins_Online_English_Dictionary, http://en.wikipedia.org/wiki/Urine_test_strip "Wikipedia"]
synonym: "machine read urine dipstick test" RELATED []
is_a: MMO:0000171 ! urine test strip
created_by: mshimoyama
creation_date: 2011-02-01T09:28:00Z

[Term]
id: MMO:0000181
name: manually read urine test strip
def: "A solid phase colorimetric assay utilizing a strip of paper, or of plastic with one or more attached pads of paper, impregnated with a reagent that reacts with an element or compound is dipped into the urine sample, allowed to react for a specified period of time and the results then assessed by a visual comparison with a standard chromatic/color scale." [Collins:Collins_Online_English_Dictionary, http://en.wikipedia.org/wiki/Urine_test_strip "Wikipedia"]
synonym: "manually read urine dipstick test" RELATED []
is_a: MMO:0000171 ! urine test strip
created_by: mshimoyama
creation_date: 2011-02-01T09:28:26Z

[Term]
id: MMO:0000182
name: machine read urine amylase test strip
is_a: MMO:0000180 ! machine read urine test strip
created_by: mshimoyama
creation_date: 2011-02-01T09:46:42Z

[Term]
id: MMO:0000183
name: machine read urine glucose test strip
is_a: MMO:0000180 ! machine read urine test strip
created_by: mshimoyama
creation_date: 2011-02-01T09:47:05Z

[Term]
id: MMO:0000184
name: machine read urine cortisol test strip
is_a: MMO:0000180 ! machine read urine test strip
created_by: mshimoyama
creation_date: 2011-02-01T09:47:37Z

[Term]
id: MMO:0000185
name: machine read urine microalbumin test strip
def: "A solid phase colorimetric assay to detect very low levels of albumin, the major blood plasma protein which is responsible for much of the plasma colloidal osmotic pressure and serves as a transport protein for large organic anions such as fatty acids and bilirubin, in a specified sample of urine, in which a strip of paper, or of plastic with one or more attached pads of paper, impregnated with a reagent that reacts with albumin is dipped into the urine sample, allowed to react for a specified period of time and then the results are assessed by an automated analyzer." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-0323057479, ISBN:978-1416049982, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed]
is_a: MMO:0000180 ! machine read urine test strip
is_a: MMO:0000336 ! urine microalbumin analysis
created_by: mshimoyama
creation_date: 2011-02-01T09:47:55Z

[Term]
id: MMO:0000186
name: machine read urine sodium test strip
def: "A solid phase colorimetric assay utilizing a strip of paper, or of plastic with one or more attached pads of paper, impregnated with a reagent that specifically reacts with sodium ions. The strip is dipped into the urine sample, allowed to react for a specified period of time and the results assessed by an automated analyzer, that is, a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Collins:Collins_Online_English_Dictionary, http://en.wikipedia.org/wiki/Urine_test_strip "Wikipedia", Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "machine read urine Na+ test strip" RELATED []
is_a: MMO:0000180 ! machine read urine test strip
is_a: MMO:0000464 ! urine sodium test strip
created_by: mshimoyama
creation_date: 2011-02-01T09:48:14Z

[Term]
id: MMO:0000187
name: machine read urine potassium test strip
def: "A solid phase colorimetric assay utilizing a strip of paper, or of plastic with one or more attached pads of paper, impregnated with a reagent that specifically reacts with potassium ions. The strip is dipped into the urine sample, allowed to react for a specified period of time and the results assessed by an automated analyzer, that is, a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Collins:Collins_Online_English_Dictionary, http://en.wikipedia.org/wiki/Urine_test_strip "Wikipedia", Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "machine read urine K+ test strip" RELATED []
is_a: MMO:0000180 ! machine read urine test strip
is_a: MMO:0000463 ! urine potassium test strip
created_by: mshimoyama
creation_date: 2011-02-01T09:48:28Z

[Term]
id: MMO:0000188
name: machine read urine uric acid test strip
is_a: MMO:0000180 ! machine read urine test strip
created_by: mshimoyama
creation_date: 2011-02-01T09:48:46Z

[Term]
id: MMO:0000189
name: blood glucose test strip
def: "A test strip or dipstick containing a reagent which reacts with glucose in blood." [ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed]
is_a: MMO:0000112 ! blood glucose analysis
created_by: mshimoyama
creation_date: 2011-02-01T01:51:37Z

[Term]
id: MMO:0000190
name: machine read blood glucose test strip
def: "A strip or dipstick containing a reagent which reacts with glucose in blood and is read by an automated analyzer." [ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed]
is_a: MMO:0000189 ! blood glucose test strip
created_by: mshimoyama
creation_date: 2011-02-01T01:52:01Z

[Term]
id: MMO:0000191
name: dial skin fold caliper method
def: "Method to measure thickness, for example, of a fold of skin, using a caliper with dial and arrow that points to the reading." [http://www.skinfold-caliper.com/ "Harpenden"]
is_a: MMO:0000080 ! skin fold caliper method
created_by: mshimoyama
creation_date: 2011-02-03T08:44:11Z

[Term]
id: MMO:0000192
name: digital skin fold caliper method
def: "A caliper for measuring skin fold thickness with a digital readout and computation of percent body fat." [http://www.formulamedical.com "FormulaMedical"]
is_a: MMO:0000080 ! skin fold caliper method
created_by: mshimoyama
creation_date: 2011-02-03T08:46:54Z

[Term]
id: MMO:0000193
name: in vivo thermometry
def: "A method performed on a living organism using an instrument with a defined scale for determining temperature, that is, the degree of heat or cold, of an object or individual or a portion of an individual's body." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "thermometer method" RELATED []
is_a: MMO:0000026 ! in vivo method
created_by: mshimoyama
creation_date: 2011-02-03T08:51:50Z

[Term]
id: MMO:0000194
name: manual rectal thermometry
def: "A method which uses a manual thermometer, an instrument with a defined scale for determining temperature usually consisting of a tube containing a temperature-responsive substance such as mercury or alcohol the results of which are assessed by a person without the assistance of automated instrumentation, inserted into the rectum of an organism, that is, the  terminal portion of the large intestine, to measure body temperature." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "manual rectal thermometer method" RELATED []
is_a: MMO:0000193 ! in vivo thermometry
created_by: mshimoyama
creation_date: 2011-02-03T08:57:06Z

[Term]
id: MMO:0000195
name: manual oral thermometry
def: "A method which uses a manual thermometer, an instrument with a defined scale for determining temperature usually consisting of a tube containing a temperature-responsive substance such as mercury or alcohol the results of which are assessed by a person without the assistance of automated instrumentation, placed in the mouth of an organism, most commonly under the tongue, to measure body temperature." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "manual oral thermometer method" RELATED []
is_a: MMO:0000193 ! in vivo thermometry
created_by: mshimoyama
creation_date: 2011-02-03T08:58:41Z

[Term]
id: MMO:0000196
name: digital oral thermometry
def: "A method which uses a digital thermometer, an instrument with a defined scale for determining temperature which presents its measurements in the form of discrete numeric symbols, placed in the mouth of an organism, most commonly under the tongue, to measure body temperature." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "digital oral thermometer method" RELATED []
is_a: MMO:0000193 ! in vivo thermometry
created_by: mshimoyama
creation_date: 2011-02-03T08:59:53Z

[Term]
id: MMO:0000197
name: fluid-filled catheter in isolated perfused lung
is_a: MMO:0000083 ! isolated perfused lung method
created_by: JSmith
creation_date: 2012-03-15T03:02:06Z

[Term]
id: MMO:0000198
name: doppler ultrasound
def: "Technique using visualization of deep structures of the body by recording the reflections of pulses of ultrasonic waves directed into the tissues. It uses the shifts in frequency between emitted ultrasonic waves and their echoes to measure the velocities of moving objects." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000024 ! ultrasound method
created_by: mshimoyama
creation_date: 2011-02-03T04:26:58Z

[Term]
id: MMO:0000199
name: continuous wave doppler ultrasound
def: "Doppler ultrasonography using two transducers, with one continuously transmitting and the other continuously recording the ultrasonic waves." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000198 ! doppler ultrasound
created_by: mshimoyama
creation_date: 2011-02-04T08:14:56Z

[Term]
id: MMO:0000200
name: pulsed wave doppler ultrasound
def: "Doppler ultrasonography in which a single transducer alternately transmits and records ultrasonic waves." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000198 ! doppler ultrasound
created_by: mshimoyama
creation_date: 2011-02-04T08:17:22Z

[Term]
id: MMO:0000201
name: sphygmomanometry
def: "A method which employs a pressure meter to measure blood pressure." [http://en.wikipedia.org/wiki/Sphygmomanometry "Wikipedia"]
synonym: "sphygmomanometer method" EXACT []
synonym: "sphygmometer method" RELATED []
is_a: MMO:0000026 ! in vivo method
created_by: mshimoyama
creation_date: 2011-02-04T10:23:09Z

[Term]
id: MMO:0000202
name: encephalography
def: "Radiography demonstrating the intracranial fluid-containing spaces after the withdrawal of cerebrospinal fluid and the introduction of air or other gas." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "air encephalography" RELATED []
is_a: MMO:0000124 ! in vivo radiography
created_by: mshimoyama
creation_date: 2011-02-04T02:41:46Z

[Term]
id: MMO:0000203
name: fluid-filled catheter with pressure transducer in isolated perfused lung
is_a: MMO:0000197 ! fluid-filled catheter in isolated perfused lung
created_by: JSmith
creation_date: 2012-03-15T03:09:37Z

[Term]
id: MMO:0000204
name: glucose tolerance analysis
def: "A test in which glucose is given and blood samples taken afterward at specific time interval(s) to determine how quickly it is cleared from the blood." [http://en.wikipedia.org/wiki/ "Wikipedia"]
is_a: MMO:0000112 ! blood glucose analysis
created_by: mshimoyama
creation_date: 2011-02-04T03:19:03Z

[Term]
id: MMO:0000205
name: balloon tipped catheter in isolated perfused heartr
is_a: MMO:0000028 ! isolated perfused heart method
created_by: JSmith
creation_date: 2012-03-15T03:15:31Z

[Term]
id: MMO:0000206
name: tissue force analysis
def: "Method involving the use of an instrument which measures the energy applied by a tissue so that it initiates motion, changes the speed or direction of motion, alters the size or shape of an object, or produces an elastic strain on a system, after that tissue has been removed from the body." [Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000161 ! isolated tissue method
created_by: JSmith
creation_date: 2012-03-15T05:24:01Z

[Term]
id: MMO:0000207
name: tissue force analysis utilizing a force transducer
def: "Method involving the use of an instrument which measures the energy applied by a tissue so that it initiates motion, changes the speed or direction of motion, alters the size or shape of an object, or produces an elastic strain on a system, when such a measurement is made on a tissue which has been removed from the body and involves the conversion of that energy into another form, such as an electrical signal, to be recorded." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000206 ! tissue force analysis
created_by: JSmith
creation_date: 2012-03-15T05:25:30Z

[Term]
id: MMO:0000208
name: wire myography using a Digi-Med tissue force analysis system with force transducer
is_a: MMO:0000342 ! wire myography
created_by: JSmith
creation_date: 2012-03-15T05:26:18Z

[Term]
id: MMO:0000209
name: body length measuring method
def: "A procedure to measure the full length of the intact body of an organism, that is, the extent of the body along its greatest dimension." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed]
is_a: MMO:0000119 ! body measuring method
created_by: JSmith
creation_date: 2012-03-20T02:58:14Z

[Term]
id: MMO:0000210
name: in vivo measuring stick method
def: "An experimental procedure performed in or on a living body, for example, a procedure performed on an organ in situ or on the entire living organism, which employs a measuring instrument having a sequence of marks at regular intervals; used as a reference in making measurements of length." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://www.vocabulary.com/dictionary/measuring_stick#word=measuring%20stick "Website", ISBN:978-1416049982]
is_a: MMO:0000492 ! in vivo linear measurement method
created_by: JSmith
creation_date: 2012-03-20T02:58:53Z

[Term]
id: MMO:0000211
name: in vivo ruler method
def: "An experimental procedure performed in or on a living body, for example, a procedure performed on an organ in situ or on the entire living organism, which employs a strip of wood, metal, or other material, having straight edges and graduated, for example in millimetres or inches, used for measuring lengths." [Collins:Collins_Online_English_Dictionary, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000210 ! in vivo measuring stick method
created_by: JSmith
creation_date: 2012-03-20T03:00:33Z

[Term]
id: MMO:0000212
name: ex vivo volume measurement method
def: "Any instrument, procedure, or technique by which the size of the three dimensional space occupied by a substance or other entity distinct from or removed from an organism, is ascertained." [American_Heritage:The_American_Heritage_Science_Dictionary_2005]
is_a: MMO:0000027 ! ex vivo method
created_by: JSmith
creation_date: 2012-03-21T02:01:29Z

[Term]
id: MMO:0000213
name: graduated cylinder
def: "A tall narrow container with a volume scale used especially for measuring liquids." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed]
is_a: MMO:0000212 ! ex vivo volume measurement method
created_by: JSmith
creation_date: 2012-03-21T02:01:59Z

[Term]
id: MMO:0000214
name: hematocrit analysis
def: "Any method for measuring the percentage of whole blood volume occupied by red blood cells." [ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed]
is_a: MMO:0000030 ! ex vivo blood analysis
created_by: JSmith
creation_date: 2012-03-30T12:18:27Z

[Term]
id: MMO:0000215
name: microhematocrit tube assay with visual assessment
def: "Whole blood is collected in a microhematocrit tube and the height of the red blood cell column is measured after centrifugation." [ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed]
is_a: MMO:0000214 ! hematocrit analysis
created_by: JSmith
creation_date: 2012-03-30T12:23:54Z

[Term]
id: MMO:0000216
name: blood free fatty acid analysis
def: "A laboratory test which measures the level of free fatty acids in blood. Free fatty acids are nonesterified organic acids consisting of a long hydrocarbon chain ending in a carboxyl group, released by the hydrolysis of triglycerides within adipose tissue." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "blood free fatty acid measurement test" EXACT []
synonym: "blood NEFA analysis" EXACT []
is_a: MMO:0000038 ! blood lipid analysis
created_by: JSmith
creation_date: 2012-06-08T02:51:27Z

[Term]
id: MMO:0000217
name: scale
def: "An instrument or machine for weighing." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed]
is_a: MMO:0000016 ! body weighing method
created_by: JSmith
creation_date: 2012-07-03T02:41:09Z

[Term]
id: MMO:0000218
name: baby weighing scale
def: "An instrument or machine for weighing which is specifically of a type used for weighing infants." [RGD:JRS]
is_a: MMO:0000217 ! scale
created_by: JSmith
creation_date: 2012-07-03T02:47:18Z

[Term]
id: MMO:0000219
name: ex vivo microscopy with digital image analysis
def: "Any method performed outside the living body which incorporates use of microscopy followed by use of computer software to analyze the resulting microscopic images. Microscopy is examination or observation of material using an instrument that employs a lens or a combination of lenses to produce magnified images." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000109 ! ex vivo microscopy
created_by: JSmith
creation_date: 2012-07-03T02:56:44Z

[Term]
id: MMO:0000220
name: ex vivo light microscopy with digital image analysis
def: "A method performed outside the living body which incorporates use of light microscopy to produce picture files stored as data expressed in a discrete numerical form, followed by use of computer software to evaluate these resulting microscopic images. Light microscopy is the examination or observation of material through a light microscope, an optical instrument that uses visible light (electromagnetic radiation with wavelengths between approximately 390 and 700 nm) processed through a lens or a combination of lenses to produce magnified images." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Visible_spectrum "Wikipedia", http://www.answers.com/ "Website", ISBN:978-1416049982]
is_a: MMO:0000111 ! ex vivo light microscopy
is_a: MMO:0000219 ! ex vivo microscopy with digital image analysis
created_by: JSmith
creation_date: 2012-07-03T03:05:11Z

[Term]
id: MMO:0000221
name: ex vivo electron microscopy with digital image analysis
def: "A method which incorporates use of electron microscopy, that is, examination or observation of material performed outside the living body through a microscope using beams of electrons, negatively charged elementary particles, to produce magnified images, followed by use of computer software to analyze the resulting microscopic images." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://www.answers.com/ "Website", ISBN:978-1416049982]
is_a: MMO:0000110 ! ex vivo electron microscopy
is_a: MMO:0000219 ! ex vivo microscopy with digital image analysis
created_by: JSmith
creation_date: 2012-07-03T03:08:20Z

[Term]
id: MMO:0000222
name: isolated cell method
def: "Any method which is performed on cells which have been isolated from a tissue of an organism and/or cultured in vitro." [RGD:JRS]
is_a: MMO:0000027 ! ex vivo method
created_by: JSmith
creation_date: 2012-07-09T11:45:28Z

[Term]
id: MMO:0000223
name: isolated cell volume measurement method
def: "Any method by which the volume of the cells isolated from a tissue of an organism and/or cultured in vitro are measured." [RGD:JRS]
is_a: MMO:0000212 ! ex vivo volume measurement method
is_a: MMO:0000222 ! isolated cell method
created_by: JSmith
creation_date: 2012-07-09T11:48:44Z

[Term]
id: MMO:0000224
name: isolated cell counting method
def: "Any method by which the number of cells isolated from a tissue of an organism and/or cultured in vitro in a sample are determined." [RGD:JRS]
is_a: MMO:0000222 ! isolated cell method
created_by: JSmith
creation_date: 2012-07-09T11:51:06Z

[Term]
id: MMO:0000225
name: automated cell/particle size/count analysis method
def: "A method which utilizes a laboratory instrument that determines the size and/or number of cells or particles in a sample in an automated fashion, that is, following a predetermined sequence of individual operations repeatedly and essentially without external influence or control." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Mosby:Mosbys_Medical_Dictionary--8th_Ed, RGD:JRS]
synonym: "automated cell/particle size/count analyzer" RELATED []
is_a: MMO:0000223 ! isolated cell volume measurement method
is_a: MMO:0000224 ! isolated cell counting method
created_by: JSmith
creation_date: 2012-07-09T11:54:25Z

[Term]
id: MMO:0000226
name: Coulter Multisizer automated cell/particle size/count analysis method
def: "A method that utilizes a laboratory instrument produced by Beckman Coulter, Incorporated which measures the size (i.e. volume and surface area) and/or number of cells or particles in a sample in an automated fashion." [https://www.beckmancoulter.com/ "Website", RGD:JRS]
synonym: "Coulter Multisizer automated cell/particle size/count analyzer" RELATED []
synonym: "Multisizer COULTER COUNTER" RELATED []
is_a: MMO:0000227 ! Coulter counter cell/particle size/count analysis method
created_by: JSmith
creation_date: 2012-07-09T11:57:21Z

[Term]
id: MMO:0000227
name: Coulter counter cell/particle size/count analysis method
def: "A method that utilizes a laboratory instrument designed to count the number and/or assess the size of small particles (e.g. biological cells) in a given volume of a suspension by monitoring the decreases in electrical conductivity through a small orifice caused by the particles passing through the orifice." [Dictionary:Electrochemistry_Dictionary_Online]
synonym: "Coulter counter cell/particle size/count analyzer" RELATED []
is_a: MMO:0000225 ! automated cell/particle size/count analysis method
created_by: JSmith
creation_date: 2012-07-09T12:11:16Z

[Term]
id: MMO:0000228
name: ultrasonic flowmeter
def: "Method which incorporates use of a device which measures the flow velocity of a fluid or gas by measuring the difference of the transit time of ultrasonic pulses propagating in and against flow direction." [http://en.wikipedia.org/wiki/Ultrasonic_flow_meter "Wikipedia"]
synonym: "ultrasonic flow meter" EXACT []
is_a: MMO:0000024 ! ultrasound method
created_by: JSmith
creation_date: 2012-07-10T02:01:58Z

[Term]
id: MMO:0000229
name: atomic spectrometry
def: "A method for measuring the atomic composition of a solution or solid substance by converting it to a vapor state and measuring either the emission or absorption of electromagnetic radiation by the component atoms." [McGraw-Hill:McGraw-Hill_Dictionary_of_Scientific_and_Technical_Terms]
synonym: "atomic spectroscopy" RELATED []
is_a: MMO:0000172 ! spectrometry
created_by: JSmith
creation_date: 2012-07-10T03:17:54Z

[Term]
id: MMO:0000230
name: atomic emission spectrometry
def: "A form of atomic spectroscopy in which one observes the emission of light at discrete wavelengths by atoms which have been electronically excited by collisions with other atoms and molecules in a hot gas." [McGraw-Hill:McGraw-Hill_Dictionary_of_Scientific_and_Technical_Terms]
synonym: "AES" RELATED []
synonym: "atomic emission spectroscopy" RELATED []
is_a: MMO:0000229 ! atomic spectrometry
is_a: MMO:0000583 ! ex vivo analysis of atomic composition
created_by: JSmith
creation_date: 2012-07-10T03:44:38Z

[Term]
id: MMO:0000231
name: inductively coupled plasma-atomic emission spectrometry
def: "A type of atomic spectroscopy in which the light emitted by atoms and ions in an inductively coupled plasma is observed. An inductively coupled plasma (ICP) is a type of plasma source in which the energy is supplied by electrical currents which are produced by electromagnetic induction, that is, by time-varying magnetic fields." [http://en.wikipedia.org/wiki/Inductively_coupled_plasma "Wikipedia", McGraw-Hill:McGraw-Hill_Dictionary_of_Scientific_and_Technical_Terms]
synonym: "ICP-AES" RELATED []
synonym: "ICP-OES" RELATED []
synonym: "inductively coupled plasma-atomic emission spectroscopy" EXACT []
synonym: "inductively coupled plasma-optical emission spectrometry" EXACT []
is_a: MMO:0000230 ! atomic emission spectrometry
created_by: JSmith
creation_date: 2012-07-10T03:50:16Z

[Term]
id: MMO:0000232
name: atomic absorption spectrometry
def: "A spectroanalytical procedure for the quantitative determination of chemical elements employing the absorption of optical radiation (light) by free atoms in the gaseous state." [http://en.wikipedia.org/wiki/Atomic_absorption_spectroscopy "Wikipedia"]
synonym: "AAS" RELATED []
synonym: "atomic absorption spectroscopy" RELATED []
is_a: MMO:0000229 ! atomic spectrometry
created_by: JSmith
creation_date: 2012-07-10T04:08:05Z

[Term]
id: MMO:0000233
name: blood triglyceride analysis
def: "A laboratory test which measures the level of triglyceride, the naturally occurring ester of three fatty acids and glycerol that is the chief constituent of fat, in whole blood." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed]
synonym: "blood triglyceride measurement test" RELATED []
is_a: MMO:0000038 ! blood lipid analysis
created_by: JSmith
creation_date: 2012-07-10T04:46:42Z

[Term]
id: MMO:0000234
name: plasma triglyceride analysis
def: "A laboratory test which measures the level of triglyceride, the naturally occurring ester of three fatty acids and glycerol that is the chief constituent of fat, in plasma. Plasma is the fluid portion of the blood in which the particulate components are suspended, or from which the particulate components have been removed by centrifugation or settling without clotting." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "plasma triglyceride measurement test" RELATED []
is_a: MMO:0000233 ! blood triglyceride analysis
created_by: JSmith
creation_date: 2012-07-10T04:56:49Z

[Term]
id: MMO:0000235
name: body fluid collection method
def: "Any method by which a bodily fluid such as blood, lymph, urine, etc. is collected." [RGD:JRS]
is_a: MMO:0000026 ! in vivo method
created_by: JSmith
creation_date: 2012-07-10T05:05:07Z

[Term]
id: MMO:0000236
name: ureter indwelling catheter method
def: "Method in which a hollow, flexible tube is inserted into the ureter, the duct that conveys urine from the kidney to the urinary bladder, and urine is collected." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed]
is_a: MMO:0000235 ! body fluid collection method
created_by: JSmith
creation_date: 2012-07-10T05:10:25Z

[Term]
id: MMO:0000237
name: radioactivity measurement method
def: "Any method which measures the level or type of energy emitted by an isotope having an unstable nucleus and emitting characteristic radiation during its decay to a stable form." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000027 ! ex vivo method
created_by: JSmith
creation_date: 2012-07-10T05:17:09Z

[Term]
id: MMO:0000238
name: liquid scintillation counting
def: "A method for measuring radiation emitted from radioactive isotopes suspended in a solvent containing a fluor or scintillant which converts the isotope's emissions into pulses of light which are in turn detected by a photomultiplier." [http://en.wikipedia.org/wiki/Liquid_scintillation_counting "Wikipedia", Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "liquid scintillation counter" RELATED []
is_a: MMO:0000237 ! radioactivity measurement method
created_by: JSmith
creation_date: 2012-07-10T05:22:11Z

[Term]
id: MMO:0000239
name: cell-based biologic assay
def: "Any method to determine one or more biologic factors, i.e., variables that influence the viability and/or functioning of living cells or tissues, in isolated cells." [Mosby:Mosbys_Dental_Dictionary--2nd_Ed, RGD:JRS]
is_a: MMO:0000222 ! isolated cell method
created_by: JSmith
creation_date: 2012-07-10T05:43:58Z

[Term]
id: MMO:0000240
name: glucose uptake assay
is_a: MMO:0000239 ! cell-based biologic assay
created_by: JSmith
creation_date: 2012-07-10T05:52:10Z

[Term]
id: MMO:0000241
name: lipolysis assay
def: "An assay which measures the amount of hydrolysis of fat and/or lipids in isolated cells." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed]
is_a: MMO:0000239 ! cell-based biologic assay
created_by: JSmith
creation_date: 2012-07-10T05:52:46Z

[Term]
id: MMO:0000242
name: radioactive glucose uptake assay
def: "An assay which measures the active transport of radioactively labeled glucose into isolated cells." [RGD:JRS]
is_a: MMO:0000240 ! glucose uptake assay
created_by: JSmith
creation_date: 2012-07-10T05:53:10Z

[Term]
id: MMO:0000243
name: radioactive glucose uptake assay with liquid scintillation counting
def: "An assay which measures the active transport of radioactively labeled glucose into isolated cells in which the incorporated glucose is measured by counting all or a portion of the sample in a liquid scintillation counter." [RGD:JRS]
is_a: MMO:0000238 ! liquid scintillation counting
is_a: MMO:0000242 ! radioactive glucose uptake assay
created_by: JSmith
creation_date: 2012-07-10T05:54:58Z

[Term]
id: MMO:0000244
name: fluorescent glucose uptake assay
def: "An assay which measures the active transport of fluorescently labeled glucose into isolated cells." [RGD:JRS]
is_a: MMO:0000240 ! glucose uptake assay
created_by: JSmith
creation_date: 2012-07-10T05:57:35Z

[Term]
id: MMO:0000245
name: lipolysis assay measuring glycerol release
def: "Assay which measures release of glycerol, the trihydroxy sugar alcohol that is the backbone of many lipids, from isolated cells such as adipocytes to quantifiy the hydrolysis of fat and/or lipids in the cells." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed]
is_a: MMO:0000241 ! lipolysis assay
created_by: JSmith
creation_date: 2012-07-10T05:59:32Z

[Term]
id: MMO:0000246
name: lipolysis assay measuring free fatty acid release
def: "Assay which measures release of free fatty acids from isolated cells such as adipocytes to quantifiy the hydrolysis of fat and/or lipids in the cells. Free fatty acids are non-esterified fatty acids released by the hydrolysis of triglycerides within adipose tissue, which can be used as an immediate source of energy by many organs and can be converted by the liver into ketone bodies." [Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000241 ! lipolysis assay
created_by: JSmith
creation_date: 2012-07-10T06:11:04Z

[Term]
id: MMO:0000247
name: fluorometry
def: "An analytical technique for identifying and characterizing minute amounts of a substance by excitation of the substance with a beam of ultraviolet light and detection and measurement of the characteristic wavelength of fluorescent light emitted." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "fluorophotometry" EXACT []
synonym: "spectrofluorophotometry" EXACT []
is_a: MMO:0000173 ! spectrophotometry
created_by: JSmith
creation_date: 2012-07-12T03:14:39Z

[Term]
id: MMO:0000248
name: aggregometry
def: "Any method used to measure the ability of whole blood or blood platelets to aggregate, coagulate or clot." [Gale:Gale_Encyclopedia_of_Medicine]
is_a: MMO:0000030 ! ex vivo blood analysis
created_by: JSmith
creation_date: 2012-07-12T03:26:08Z

[Term]
id: MMO:0000249
name: light transmission aggregometry
def: "Method which uses changes in the transmission of light through blood or platelet rich plasma during aggregation to assess the ability of the platelets in the sample to aggregate, coagulate or clot in response to an agonist." [http://www.practical-haemostasis.com/Platelets/platelet_function_testing_lta.html "Website"]
synonym: "Born aggregometry" EXACT []
synonym: "LTA" EXACT []
synonym: "optical aggregometry" RELATED []
is_a: MMO:0000248 ! aggregometry
created_by: JSmith
creation_date: 2012-07-12T03:35:29Z

[Term]
id: MMO:0000250
name: intracellular calcium assay
def: "Method to determine the level or concentration of calcium inside isolated cells." [RGD:JRS]
is_a: MMO:0000239 ! cell-based biologic assay
created_by: JSmith
creation_date: 2012-07-12T03:51:02Z

[Term]
id: MMO:0000251
name: fluorescent intracellular calcium assay
def: "Method which employs a fluorescent dye to assess the level or concentration inside isolated cells." [RGD:JRS]
is_a: MMO:0000250 ! intracellular calcium assay
created_by: JSmith
creation_date: 2012-07-12T03:53:07Z

[Term]
id: MMO:0000252
name: Fura-2 intracellular calcium assay
def: "Method which employs Fura-2 or a related compound such as Fura 2-AM, its membrane-permeable derivative, to measure the amount or concentration of calcium inside isolated cells.  Output is determined by fluorometry." [PMID:3838314]
is_a: MMO:0000247 ! fluorometry
is_a: MMO:0000251 ! fluorescent intracellular calcium assay
created_by: JSmith
creation_date: 2012-07-12T03:54:59Z

[Term]
id: MMO:0000253
name: blood urea nitrogen analysis
def: "A test which measures the amount of nitrogen present in the blood in the form of urea, the chief nitrogenous end product of protein metabolism. Urea is formed in the liver from amino acids and from ammonia compounds and is found in urine, blood, and lymph." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "BUN test" EXACT []
is_a: MMO:0000030 ! ex vivo blood analysis
created_by: JSmith
creation_date: 2012-07-18T12:29:32Z

[Term]
id: MMO:0000254
name: body movement/behavior method
def: "Any method which can be used to measure movement of all or part of the body of an organism, including those categorized or interpreted as behavior." [RGD:JRS]
is_a: MMO:0000026 ! in vivo method
created_by: JSmith
creation_date: 2012-07-24T02:58:03Z

[Term]
id: MMO:0000255
name: movement/behavior test apparatus method
def: "A method utilizing a piece of physical instrumentation, machinery or equipment designed and used to measure the movements and/or behaviors of an organism." [Oxford:The_Online_Compact_Oxford_English_Dictionary]
is_a: MMO:0000254 ! body movement/behavior method
created_by: JSmith
creation_date: 2012-07-24T03:01:57Z

[Term]
id: MMO:0000256
name: movement/behavior test enclosure method
def: "A test utilizing an experimental instrument composed of a demarcated area used to measure and/or record movement or behavior of an organism." [RGD:JRS]
is_a: MMO:0000255 ! movement/behavior test apparatus method
created_by: JSmith
creation_date: 2012-07-24T03:08:23Z

[Term]
id: MMO:0000257
name: movement/behavior test maze method
def: "A method that utilizes an experimental apparatus made up of multiple components which requires that an experimental subject makes a choice or a series of choices and/or learn a specific solution to a problem. Used to test movement or behavior of an organism." [RGD:JRS]
is_a: MMO:0000255 ! movement/behavior test apparatus method
created_by: JSmith
creation_date: 2012-07-24T03:37:16Z

[Term]
id: MMO:0000258
name: open field apparatus method
def: "A test utilizing an enclosure consisting of a single area bordered by clear or opaque walls, used to measure movement, exploratory behavior, etc of an experimental subject." [http://www.sandiegoinstruments.com "Website"]
synonym: "open field test" RELATED []
is_a: MMO:0000256 ! movement/behavior test enclosure method
created_by: JSmith
creation_date: 2012-07-24T03:45:09Z

[Term]
id: MMO:0000259
name: center of open field apparatus
def: "The open center area of an open field apparatus, an enclosure consisting of a single area bordered by clear or opaque walls, used to measure movement, exploratory behavior, etc of an experimental subject." [RGD:JRS]
is_a: MMO:0000258 ! open field apparatus method
created_by: JSmith
creation_date: 2012-07-24T04:36:13Z

[Term]
id: MMO:0000260
name: periphery of open field apparatus
def: "Any part of the area immediately adjacent to the walls of an open field apparatus, an enclosure consisting of a single area bordered by clear or opaque walls, used to measure movement, exploratory behavior, etc of an experimental subject." [RGD:JRS]
is_a: MMO:0000258 ! open field apparatus method
created_by: JSmith
creation_date: 2012-07-24T04:38:23Z

[Term]
id: MMO:0000261
name: corner of open field apparatus
def: "The area immediately adjacent to the junction of two walls in a square or rectangular open field apparatus, an enclosure consisting of a single area bordered by clear or opaque walls, used to measure movement, exploratory behavior, etc of an experimental subject." [RGD:JRS]
is_a: MMO:0000258 ! open field apparatus method
created_by: JSmith
creation_date: 2012-07-24T04:45:31Z

[Term]
id: MMO:0000262
name: elevated plus maze apparatus method
def: "A method which utilizes an experimental apparatus consisting of four arms, usually two enclosed and two open, in the shape of a plus (+) upon which the test animal can walk. The maze is elevated a set distance, for example 40 to 60 centimeters, above the floor or platform upon which the apparatus sits." [PMID:22294128]
synonym: "elevated plus maze test" RELATED []
synonym: "EPM apparatus method" RELATED []
synonym: "EPM test" RELATED []
is_a: MMO:0000257 ! movement/behavior test maze method
created_by: JSmith
creation_date: 2012-07-24T04:48:52Z

[Term]
id: MMO:0000263
name: center of elevated plus maze apparatus
def: "The area in an elevated plus maze apparatus where the four arms meet. An elevated plus maze is an experimental apparatus which consists of four arms, usually two enclosed and two open, in the shape of a plus (+) upon which the test animal can walk. The maze is elevated a set distance, for example 40 to 60 cm, above the floor or platform upon which the apparatus sits." [PMID:22294128]
synonym: "center of EPM" EXACT []
is_a: MMO:0000262 ! elevated plus maze apparatus method
created_by: JSmith
creation_date: 2012-07-24T05:06:57Z

[Term]
id: MMO:0000264
name: arm(s) of elevated plus maze apparatus
def: "Any of the arms, either open or enclosed, of an elevated plus maze apparatus, an experimental apparatus which consists of four arms, usually two enclosed and two open, in the shape of a plus (+) upon which the test animal can walk. The maze is elevated a set distance, for example 40 to 60 cm, above the floor or platform upon which the apparatus sits." [PMID:22294128]
synonym: "arms of EPM" EXACT []
is_a: MMO:0000262 ! elevated plus maze apparatus method
created_by: JSmith
creation_date: 2012-07-24T05:10:26Z

[Term]
id: MMO:0000265
name: enclosed arm of elevated plus maze apparatus
def: "One or both of the arms of an elevated plus maze apparatus which are bounded on two or three sides by walls, forming an observable enclosure. An elevated plus maze is an experimental apparatus which consists of four arms, usually two enclosed and two open, in the shape of a plus (+) upon which the test animal can walk. The maze is elevated a set distance, for example 40 to 60 cm, above the floor or platform upon which the apparatus sits." [PMID:22294128]
synonym: "closed arm of elevated plus maze apparatus" EXACT []
synonym: "enclosed arm of EPM" EXACT []
is_a: MMO:0000264 ! arm(s) of elevated plus maze apparatus
created_by: JSmith
creation_date: 2012-07-24T05:12:07Z

[Term]
id: MMO:0000266
name: open arm of elevated plus maze apparatus
def: "One or both of the arms of an elevated plus maze apparatus which are not bounded or enclosed with walls. An elevated plus maze is an experimental apparatus which consists of four arms, usually two enclosed and two open, in the shape of a plus (+) upon which the test animal can walk. The maze is elevated a set distance, for example 40 to 60 cm, above the floor or platform upon which the apparatus sits." [PMID:22294128]
synonym: "open arm of EPM" EXACT []
is_a: MMO:0000264 ! arm(s) of elevated plus maze apparatus
created_by: JSmith
creation_date: 2012-07-24T05:15:31Z

[Term]
id: MMO:0000267
name: elevated T-maze apparatus method
def: "A method which utilizes an experimental apparatus consisting of three arms all or any of which may or may not be enclosed, in the shape of a T upon which the test animal can walk. The maze may include doors which can be used to close off any of the arms of the maze. The maze is elevated a set distance, for example 40 to 60 centimeters, above the floor or platform upon which the apparatus sits." [PMID:17401477]
synonym: "elevated T maze apparatus method" EXACT []
synonym: "elevated T-maze test" RELATED []
is_a: MMO:0000257 ! movement/behavior test maze method
created_by: JSmith
creation_date: 2012-07-24T05:18:55Z

[Term]
id: MMO:0000268
name: enclosed arm of elevated T-maze apparatus
def: "One or both (if there are two) arms of an elevated T-maze apparatus which are bounded on two or three sides by walls, forming an observable enclosure. An elevated T-maze is an experimental apparatus which consists of three arms in the shape of a T, upon which the test animal can walk. The maze may include doors which can be used to close off any of the arms of the maze. The maze is elevated a set distance, for example 40 to 60 cm, above the floor or platform upon which the apparatus sits." [PMID:17401477]
synonym: "closed arm of elevated T-maze apparatus" EXACT []
is_a: MMO:0000267 ! elevated T-maze apparatus method
created_by: JSmith
creation_date: 2012-07-24T05:35:26Z

[Term]
id: MMO:0000269
name: open arm of elevated T-maze apparatus
def: "One or both (if there are two) arms of an elevated T-maze apparatus which are not bounded or enclosed by walls. An elevated T-maze is an experimental apparatus which consists of three arms in the shape of a T, upon which the test animal can walk. The maze may include doors which can be used to close off any of the arms of the maze. The maze is elevated a set distance, for example 40 to 60 cm, above the floor or platform upon which the apparatus sits." [PMID:17401477]
is_a: MMO:0000267 ! elevated T-maze apparatus method
created_by: JSmith
creation_date: 2012-07-24T05:40:42Z

[Term]
id: MMO:0000270
name: blood creatinine analysis
def: "Any method for measuring creatinine, the nitrogenous compound formed as the end product of creatine metabolism, in whole blood, serum or plasma." [Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed]
is_a: MMO:0000030 ! ex vivo blood analysis
created_by: JSmith
creation_date: 2012-07-30T08:21:53Z

[Term]
id: MMO:0000271
name: serum creatinine analysis
def: "Any method for measuring creatinine, the nitrogenous compound formed as the end product of creatine metabolism, in serum." [Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed]
is_a: MMO:0000270 ! blood creatinine analysis
created_by: JSmith
creation_date: 2012-07-30T08:25:23Z

[Term]
id: MMO:0000272
name: blood urea analysis
def: "Any assay which measures the amount, level or concentration of urea in whole blood." [RGD:JRS]
comment: Not to be used for tests which return values for "blood urea nitrogen" (BUN). For that test, use MMO:0000253.
is_a: MMO:0000030 ! ex vivo blood analysis
created_by: JSmith
creation_date: 2012-08-08T02:01:01Z

[Term]
id: MMO:0000273
name: serum urea analysis
def: "An assay which measures the amount, level or concentration of urea, the chief nitrogenous endproduct of protein metabolism, in serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
comment: Not to be used for tests which return values for "serum urea nitrogen". For that test, use MMO:0000274.
is_a: MMO:0000272 ! blood urea analysis
created_by: JSmith
creation_date: 2012-08-08T02:12:43Z

[Term]
id: MMO:0000274
name: serum urea nitrogen analysis
def: "A test which measures the amount of nitrogen in the form of urea present in serum, the clear liquid that separates from blood after it has clotted completely. Urea is the chief nitrogenous end product of protein metabolism and is formed in the liver from amino acids and from ammonia compounds and is found in urine, blood, and lymph." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000253 ! blood urea nitrogen analysis
created_by: JSmith
creation_date: 2012-08-08T02:17:44Z

[Term]
id: MMO:0000275
name: urine creatinine analysis
def: "Any test which measures the amount of creatinine, the metabolized by-product of creatine, an organic acid that assists the body in producing muscle contractions, in urine." [Gale:Gale_Encyclopedia_of_Medicine]
is_a: MMO:0000147 ! urine analysis
created_by: JSmith
creation_date: 2012-08-08T02:27:52Z

[Term]
id: MMO:0000276
name: post excision length measurement
def: "Any method which measures the length an organ, tissue or other body part after it has been removed from the body." [RGD:JRS]
is_a: MMO:0000277 ! isolated body part size method
created_by: JSmith
creation_date: 2012-08-08T03:03:49Z

[Term]
id: MMO:0000277
name: isolated body part size method
def: "Any method which measures the physical dimensions, proportions, magnitude, or extent of an organ, tissue or other body part after it has been removed from the body." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed]
is_a: MMO:0000004 ! isolated body part method
created_by: JSmith
creation_date: 2012-08-08T03:05:30Z

[Term]
id: MMO:0000278
name: blood high-density lipoprotein-cholesterol measurement test
def: "A test which determines the amount of cholesterol carried in high-density lipoprotein (HDL) particles in a sample of whole blood." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "blood HDL-cholesterol test" EXACT []
is_a: MMO:0000489 ! blood differential lipoprotein-cholesterol analysis
created_by: JSmith
creation_date: 2012-08-08T04:21:02Z

[Term]
id: MMO:0000279
name: blood low-density lipoprotein-cholesterol measurement test
def: "A test which determines the amount of cholesterol carried in low-density lipoprotein (LDL) particles in blood." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "blood LDL-cholesterol test" EXACT []
is_a: MMO:0000489 ! blood differential lipoprotein-cholesterol analysis
created_by: JSmith
creation_date: 2012-08-08T04:23:38Z

[Term]
id: MMO:0000280
name: blood total cholesterol measurement test
def: "A test which determines total amount of cholesterol in blood, including cholesterol carried in any and all types of lipoprotein molecules." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000491 ! blood cholesterol analysis
created_by: JSmith
creation_date: 2012-08-08T04:24:37Z

[Term]
id: MMO:0000281
name: blood very low-density lipoprotein-cholesterol measurement test
def: "A test which determines the amount of cholesterol carried in very-low-density lipoprotein (VLDL) particles in blood." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "blood VLDL-cholesterol test" EXACT []
is_a: MMO:0000489 ! blood differential lipoprotein-cholesterol analysis
created_by: JSmith
creation_date: 2012-08-08T04:29:46Z

[Term]
id: MMO:0000282
name: plasma high-density lipoprotein-cholesterol measurement test
def: "A test which determines the amount of cholesterol carried in high-density lipoprotein (HDL) particles in a sample of plasma, the fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "plasma HDL-cholesterol test" EXACT []
is_a: MMO:0000278 ! blood high-density lipoprotein-cholesterol measurement test
created_by: JSmith
creation_date: 2012-08-08T04:35:06Z

[Term]
id: MMO:0000283
name: plasma low-density lipoprotein-cholesterol measurement test
def: "A test which determines the amount of cholesterol carried in low-density lipoprotein (LDL) particles in plasma, the fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "plasma LDL-cholesterol test" EXACT []
is_a: MMO:0000279 ! blood low-density lipoprotein-cholesterol measurement test
created_by: JSmith
creation_date: 2012-08-08T04:38:36Z

[Term]
id: MMO:0000284
name: plasma total cholesterol measurement test
def: "A test which determines total amount of cholesterol carried in lipoprotein, such as high-density lipoprotein (HDL), low-density lipoprotein (LDL) and very-low-density lipoprotein (VLDL), molecules in a volume of plasma, the fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000280 ! blood total cholesterol measurement test
created_by: JSmith
creation_date: 2012-08-08T04:39:53Z

[Term]
id: MMO:0000285
name: plasma very low-density lipoprotein-cholesterol measurement test
def: "A test which determines the amount of cholesterol carried in very-low-density lipoprotein (VLDL) particles in a volume of plasma, the fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "plasma VLDL-cholesterol test" EXACT []
is_a: MMO:0000281 ! blood very low-density lipoprotein-cholesterol measurement test
created_by: JSmith
creation_date: 2012-08-08T04:40:46Z

[Term]
id: MMO:0000286
name: molecular separation method
def: "Any method which is based upon division of the molecules in a mixture, solution or suspension into constituent or distinct elements on the basis of one or more chemical or physical properties." [Oxford:The_Online_Compact_Oxford_English_Dictionary]
is_a: MMO:0000027 ! ex vivo method
is_a: MMO:0000639 ! molecular method
created_by: JSmith
creation_date: 2012-08-08T05:06:21Z

[Term]
id: MMO:0000287
name: electrophoresis
def: "The separation of ionic solutes based on differences in their rates of migration in an applied electric field." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000286 ! molecular separation method
created_by: JSmith
creation_date: 2012-08-08T05:14:42Z

[Term]
id: MMO:0000288
name: chromatography
def: "A method of separating and identifying the components of a complex mixture by differential movement through a two-phase system, in which the movement is effected by a flow of a liquid or a gas (mobile phase) which percolates through an adsorbent (stationary phase) or a second liquid phase." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
xref: ECO:0000325
is_a: MMO:0000286 ! molecular separation method
created_by: JSmith
creation_date: 2012-08-08T05:18:27Z

[Term]
id: MMO:0000289
name: thin layer chromatography
def: "A method of separating and identifying the components of a complex mixture by differential movement through a two-phase system, in which the movement is effected by a flow of a liquid, mobile phase over a stationary phase composed of a thin layer of adsorbent such as silica gel, alumina, or cellulose on a flat, inert substrate." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Chromatography#Thin_layer_chromatography "Wikipedia", ISBN:978-1416049982]
is_a: MMO:0000288 ! chromatography
created_by: JSmith
creation_date: 2012-08-08T05:22:48Z

[Term]
id: MMO:0000290
name: blood pH analysis
def: "A test of the acidity or alkalinity of blood, expressed as the negative logarithm of the hydrogen ion concentration expressed in molarity." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000030 ! ex vivo blood analysis
created_by: JSmith
creation_date: 2012-08-08T06:16:50Z

[Term]
id: MMO:0000291
name: cell-based electrophysiological assay
def: "Any test dealing with the electrical properties of biological cells." [http://en.wikipedia.org/wiki/Electrophysiology "Wikipedia"]
is_a: MMO:0000239 ! cell-based biologic assay
created_by: JSmith
creation_date: 2012-08-09T01:03:13Z

[Term]
id: MMO:0000292
name: patch clamp technique
def: "An electrophysiological technique that uses a microelectrode to record current flow across a cell membrane or a piece of a cell membrane, thus permitting the study of a single or multiple ion channels in a cell." [http://en.wikipedia.org/wiki/Patch_clamp "Wikipedia", http://www.dddmag.com/content/glossary-drug-discovery-and-development-terms#p "Website"]
synonym: "patch clamp recording" RELATED []
synonym: "patch-clamp technique" EXACT []
is_a: MMO:0000291 ! cell-based electrophysiological assay
created_by: JSmith
creation_date: 2012-08-09T01:12:58Z

[Term]
id: MMO:0000293
name: whole-cell patch clamp technique
def: "A patch clamp technique which uses an electrode inserted into an intact cell in such a way that a high resistance seal is maintained between the electrode and the plasma membrane, allowing measurement of currents through multiple ion channels across the entire cell membrane." [http://en.wikipedia.org/wiki/Patch_clamp#Whole-cell_recording_or_whole-cell_patch "Wikipedia"]
synonym: "whole cell patch clamp recording" RELATED []
synonym: "whole-cell patch-clamp technique" EXACT []
is_a: MMO:0000292 ! patch clamp technique
created_by: JSmith
creation_date: 2012-08-09T01:19:30Z

[Term]
id: MMO:0000294
name: automated platelet count test
def: "Use of an automated analyzer to quantitate the number of platelets, the small, non-nucleated cell fragments whose activity is essential to blood clotting, in a specified volume of blood." [ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed]
synonym: "automated thrombocyte count test" RELATED []
is_a: MMO:0000146 ! automated blood cell counting method
created_by: jsmith
creation_date: 2012-08-20T04:31:52Z

[Term]
id: MMO:0000295
name: blood hemoglobin analysis
def: "Any method to determine the nature, properties, or composition of hemoglobin, the oxygen- and carbon dioxide-carrying protein in red blood cells." [ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed]
is_a: MMO:0000166 ! blood protein analysis
created_by: jsmith
creation_date: 2012-08-20T04:52:29Z

[Term]
id: MMO:0000296
name: novel cage apparatus method
def: "A test utilizing a standard cage or chamber which is unfamiliar to the subjects before the start of the experimental procedure." [http://www.ncbi.nlm.nih.gov/books/NBK5221/ "Website"]
is_a: MMO:0000256 ! movement/behavior test enclosure method
created_by: jsmith
creation_date: 2012-08-24T05:59:32Z

[Term]
id: MMO:0000297
name: novel cage apparatus test utilizing automatic movement detection system
def: "A method using a standard cage or chamber which is unfamiliar to the subjects before the start of the experimental procedure and which incorporates any type of system to detect, measure and record movement automatically." [http://www.ncbi.nlm.nih.gov/books/NBK5221/ "Website"]
is_a: MMO:0000296 ! novel cage apparatus method
created_by: jsmith
creation_date: 2012-08-24T06:05:47Z

[Term]
id: MMO:0000298
name: elevated zero maze apparatus method
def: "A method which utilizes an experimental apparatus consisting of a ring-shaped runway with the same amount of area devoted to adjacent, i.e. alternating, open (without walls) and closed (with walls) quadrants suspended a set distance above the floor or bench/table top upon which the apparatus sits." [PMID:20869983]
synonym: "elevated zero-maze apparatus method" EXACT []
synonym: "elevated zero maze test" RELATED []
is_a: MMO:0000257 ! movement/behavior test maze method
created_by: jsmith
creation_date: 2012-08-27T11:26:36Z

[Term]
id: MMO:0000299
name: open section of elevated zero maze apparatus
def: "Either of two unwalled segments of an elevated zero maze apparatus, a ring-shaped runway with the same amount of area devoted to adjacent, i.e. alternating open and closed quadrants suspended a set distance above the ground, floor or bench/table top upon which the apparatus sits." [PMID:20869983]
synonym: "open segment of elevated zero maze apparatus" RELATED []
is_a: MMO:0000298 ! elevated zero maze apparatus method
created_by: jsmith
creation_date: 2012-08-27T12:19:34Z

[Term]
id: MMO:0000300
name: enclosed section of elevated zero maze apparatus
def: "Either of two walled segments of an elevated zero maze apparatus, a ring-shaped runway with the same amount of area devoted to adjacent, i.e. alternating open and closed quadrants suspended a set distance above the ground, floor or bench/table top upon which the apparatus sits." [PMID:20869983]
synonym: "enclosed segment of elevated zero maze apparatus" EXACT []
is_a: MMO:0000298 ! elevated zero maze apparatus method
created_by: jsmith
creation_date: 2012-08-27T12:25:46Z

[Term]
id: MMO:0000301
name: two way shuttlebox apparatus method
def: "A test using a box divided into two halves in which an experimental animal must move from one compartment to the other in order to gain their reward or to avoid an adverse stimulus. The shuttlebox is considered two way because the reward or adverse stimulus can be administered in either or both sides of the apparatus." [http://psychology.wikia.com/wiki/Shuttle_boxes "Website", http://www.springerlink.com/content/j8r4800u137n37gw/ "Web_article"]
synonym: "two way shuttle box apparatus method" EXACT []
synonym: "two way shuttlebox test" RELATED []
is_a: MMO:0000256 ! movement/behavior test enclosure method
created_by: jsmith
creation_date: 2012-08-27T01:02:04Z

[Term]
id: MMO:0000302
name: active avoidance test using a two-way shuttle box apparatus
def: "Active avoidance requires performing a specific behavior in order to escape or avoid the aversive stimulus. It is a conditioning paradigm in which the animal learns to control the application of an unconditioned stimulus (US), in this case, a foot shock, by appropriately reacting to a conditioned stimulus (CS) preceding the US, such as a light cue. The first stage of avoidance learning is usually to escape from the US. With continued training, anticipatory reactions appear which enable the animal to avoid the US altogether. In the active avoidance test, the rodent is placed into a shuttle box and is trained to move to the opposite side of the box in response to a cue that signals an incoming foot shock. Movement to the opposite side of the chamber in response to the presentation of the shock-predictive cue alone is regarded as active avoidance, whereas movement to the opposite side of the chamber only after receiving foot shock is regarded as an escape response." [https://conductscience.com/maze/portfolio/active-passive-avoidance-shuttle-box/ "Website"]
is_a: MMO:0000301 ! two way shuttlebox apparatus method
created_by: jsmith
creation_date: 2012-08-27T04:31:31Z

[Term]
id: MMO:0000303
name: radioenzymatic assay
def: "An assay in which a radioactive substrate us used to quantitate enzyme activity in a sample or in which a radioactive cofactor or substrate with an added enzyme is used to quantitate the level of another substrate in a sample." [PMID:904439, RGD:JRS]
is_a: MMO:0000237 ! radioactivity measurement method
created_by: JSmith
creation_date: 2012-09-06T05:04:59Z

[Term]
id: MMO:0000304
name: radioenzymatic assay measuring enzyme level or activity
def: "An assay of the catalytic activity of an enzyme based on the use of a radioactive substrate." [http://goldbook.iupac.org/R05102.html "IUPAC"]
is_a: MMO:0000303 ! radioenzymatic assay
created_by: JSmith
creation_date: 2012-09-06T05:13:57Z

[Term]
id: MMO:0000305
name: radioenzymatic assay measuring substrate level
def: "An assay utilizing an extrinsic, that is, added enzyme and radioactive cofactor or substrate to quantitate another enzymatic substrate in a sample." [PMID:11108727]
is_a: MMO:0000303 ! radioenzymatic assay
created_by: JSmith
creation_date: 2012-09-06T05:16:08Z

[Term]
id: MMO:0000306
name: plasma creatinine analysis
is_a: MMO:0000270 ! blood creatinine analysis
created_by: JSmith
creation_date: 2012-09-13T06:19:26Z

[Term]
id: MMO:0000307
name: plasma urea nitrogen analysis
is_a: MMO:0000253 ! blood urea nitrogen analysis
created_by: JSmith
creation_date: 2012-09-13T06:20:47Z

[Term]
id: MMO:0000308
name: serum free fatty acid analysis
def: "A laboratory test which measures the level of free fatty acids in serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. Free fatty acids are nonesterified organic acids consisting of a long hydrocarbon chain ending in a carboxyl group, released by the hydrolysis of triglycerides within adipose tissue." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "serum free fatty acid measurement test" EXACT []
synonym: "serum NEFA analysis" EXACT []
is_a: MMO:0000216 ! blood free fatty acid analysis
created_by: JSmith
creation_date: 2012-09-13T06:22:43Z

[Term]
id: MMO:0000309
name: plasma free fatty acid analysis
def: "A laboratory test which measures the level of free fatty acids in plasma, the fluid portion of the blood in which the particulate components are suspended. Free fatty acids are nonesterified organic acids consisting of a long hydrocarbon chain ending in a carboxyl group, released by the hydrolysis of triglycerides within adipose tissue." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "plasma free fatty acid measurement test" EXACT []
synonym: "plasma NEFA analysis" EXACT []
is_a: MMO:0000216 ! blood free fatty acid analysis
created_by: JSmith
creation_date: 2012-09-13T06:23:01Z

[Term]
id: MMO:0000310
name: fluorescence-activated cell sorting method
def: "A technique for separating and sorting cells marked with a fluorescent label based on how much they fluoresce at a particular wavelength." [Mondofacto:Mondofacto_Online_Medical_Dictionary]
synonym: "FACS" RELATED []
synonym: "fluorescence-activated cell sorter" RELATED []
is_a: MMO:0000617 ! flow cytometry method
created_by: JSmith
creation_date: 2012-09-13T06:24:24Z

[Term]
id: MMO:0000311
name: blood hormone analysis
def: "A method to measure one or more hormones in blood. A hormone is a chemical substance which is produced in one part or organ of the body and initiates or regulates the activity of an organ or a group of cells in another part of the body." [Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000030 ! ex vivo blood analysis
created_by: JSmith
creation_date: 2012-10-04T03:03:53Z

[Term]
id: MMO:0000312
name: blood aldosterone analysis
def: "A method which measures aldosterone in the blood. Aldosterone is a mineralocorticoid steroid hormone produced by the adrenal cortex with action in the renal tubule to retain sodium, conserve water by reabsorption, and increase urinary excretion of potassium." [Mosby:Mosbys_Medical_Dictionary--8th_Ed]
comment: Only for use when the specific method of measuring the aldosterone, such as ELISA, EIA or RIA is not given.
is_a: MMO:0000311 ! blood hormone analysis
created_by: JSmith
creation_date: 2012-10-04T03:10:38Z

[Term]
id: MMO:0000313
name: plasma aldosterone analysis
def: "Any method which measures aldosterone, a mineralocorticoid steroid hormone produced by the adrenal cortex with action in the renal tubule to retain sodium, conserve water by reabsorption, and increase urinary excretion of potassium, in plasma, the fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
comment: For use when the specific method of measuring the aldosterone, such as ELISA, EIA or RIA is not given.
is_a: MMO:0000312 ! blood aldosterone analysis
created_by: JSmith
creation_date: 2012-10-04T03:15:53Z

[Term]
id: MMO:0000314
name: serum aldosterone analysis
def: "Any method which measures aldosterone, a mineralocorticoid steroid hormone produced by the adrenal cortex with action in the renal tubule to retain sodium, conserve water by reabsorption, and increase urinary excretion of potassium, in serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
comment: For use when the specific method of measuring the aldosterone, such as ELISA, EIA or RIA is not given.
is_a: MMO:0000312 ! blood aldosterone analysis
created_by: JSmith
creation_date: 2012-10-04T03:25:01Z

[Term]
id: MMO:0000315
name: plasma glucose analysis
def: "Any method to determine the level of glucose, the end product of carbohydrate metabolism, in plasma, the fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000112 ! blood glucose analysis
created_by: JSmith
creation_date: 2012-10-04T03:38:41Z

[Term]
id: MMO:0000316
name: serum glucose analysis
def: "Any method to determine the level of glucose, the end product of carbohydrate metabolism, in serum, the clear liquid that separates from blood after cells, platelets, and clotting factors have been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000112 ! blood glucose analysis
created_by: JSmith
creation_date: 2012-10-04T03:39:20Z

[Term]
id: MMO:0000317
name: flowmetry
def: "Any method used to measure the rate of flow of liquids or gases in a living organism." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000026 ! in vivo method
created_by: JSmith
creation_date: 2012-10-04T03:54:13Z

[Term]
id: MMO:0000318
name: electromagnetic flowmetry
def: "A method for measuring the rate of flow of liquids or gases in which a conductive liquid flowing through a tube such as a blood vessel in a living organism is subjected to a magnetic field and the resultant voltage, which is proportional to the velocity of movement, is measured." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000317 ! flowmetry
created_by: JSmith
creation_date: 2012-10-04T04:01:07Z

[Term]
id: MMO:0000319
name: ex vivo videomicroscopy
def: "The use of video microscopes provide a live feed image directly to a computer, TV or a LCD projector. There are several different setups for video microscopes which differ mostly based on the type of camera and the frames per second that the camera provides. The main goal for a video microscope is typically a smooth real-time video image that does not jump and is fluid." [https://www.microscopeworld.com/t-video_microscopes.aspx, https://www.sciencedirect.com/topics/medicine-and-dentistry/video-microscopy]
synonym: "ex vivo television microscopy" EXACT []
synonym: "ex vivo video microscopy" EXACT []
xref: PMID:27270176
is_a: MMO:0000111 ! ex vivo light microscopy
created_by: JSmith
creation_date: 2012-10-05T12:06:36Z

[Term]
id: MMO:0000320
name: blood insulin analysis
def: "Any method by which the level or concentration in a sample of blood of insulin is measured. Insulin is the major fuel-regulating peptide hormone produced by the beta cells of the pancreatic islets of Langerhans." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
comment: Only for use when the specific method of measuring the hormone, such as ELISA, EIA or RIA, is not given.
is_a: MMO:0000311 ! blood hormone analysis
created_by: JSmith
creation_date: 2012-10-15T04:09:51Z

[Term]
id: MMO:0000321
name: plasma insulin analysis
def: "Any method of measuring the level or concentration of insulin in a sample of plasma, the fluid portion of the blood in which the particulate components are suspended. Insulin is the major fuel-regulating peptide hormone produced by the beta cells of the pancreatic islets of Langerhans." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
comment: For use when the specific method of measuring the hormone, such as ELISA, EIA or RIA is not given.
is_a: MMO:0000320 ! blood insulin analysis
created_by: JSmith
creation_date: 2012-10-15T04:16:33Z

[Term]
id: MMO:0000322
name: serum insulin analysis
def: "Any method of measuring the level or concentration of insulin in a sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. Insulin is the major fuel-regulating peptide hormone produced by the beta cells of the pancreatic islets of Langerhans." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
comment: For use when the specific method of measuring the hormone, such as ELISA, EIA or RIA, is not given.
is_a: MMO:0000320 ! blood insulin analysis
created_by: JSmith
creation_date: 2012-10-15T04:21:46Z

[Term]
id: MMO:0000323
name: blood phospholipid analysis
def: "A laboratory test which measures the level of one or more phospholipids, phosphorus-containing lipids composed mainly of fatty acids, a phosphate group, and a simple organic molecule, in blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed]
synonym: "blood phospholipid measurement test" RELATED []
is_a: MMO:0000038 ! blood lipid analysis
created_by: JSmith
creation_date: 2012-11-16T16:13:25Z

[Term]
id: MMO:0000324
name: plasma phospholipid analysis
def: "A laboratory test which measures the level of one or more phospholipids, phosphorous-containing lipids composed mainly of fatty acids, a phosphate group, and a simple organic molecule, in plasma, the fluid portion of the blood in which the particulate components are suspended." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "plasma phospholipid measurement test" RELATED []
is_a: MMO:0000323 ! blood phospholipid analysis
created_by: JSmith
creation_date: 2012-11-16T16:26:18Z

[Term]
id: MMO:0000325
name: serum phospholipid analysis
def: "A laboratory test which measures the level of one or more phospholipids, phosphorous-containing lipids composed mainly of fatty acids, a phosphate group, and a simple organic molecule, in serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "serum phospholipid measurement test" RELATED []
is_a: MMO:0000323 ! blood phospholipid analysis
created_by: JSmith
creation_date: 2012-11-16T16:28:26Z

[Term]
id: MMO:0000326
name: intravenous glucose tolerance test
def: "A test in which glucose is injected into a vein and blood samples taken afterward at specified interval(s) to determine how quickly it is cleared from the blood." [http://en.wikipedia.org/wiki/Glucose_tolerance_test "Wikipedia"]
synonym: "intravenous glucose challenge test" RELATED []
synonym: "IVGTT" EXACT []
synonym: "IVTCT" RELATED []
is_a: MMO:0000204 ! glucose tolerance analysis
created_by: JSmith
creation_date: 2012-11-16T17:10:53Z

[Term]
id: MMO:0000327
name: colorimetry
def: "Colorimetry is a scientific technique that is used to determine the concentration of colored compounds in solutions by the application of the Beer–Lambert law (A=elc), which states that the concentration of a solute is proportional to the absorbance." [https://www.sciencedirect.com/topics/chemical-engineering/colorimetry "ScienceDirect"]
synonym: "colorimetric analysis" RELATED []
synonym: "filter photometry" EXACT []
is_a: MMO:0000704 ! photometry
created_by: JSmith
creation_date: 2013-02-12T14:44:05Z

[Term]
id: MMO:0000328
name: solid phase colorimetry
def: "A technique by which the color of a sample following a reaction carried out in or on a material characterized by structural rigidity and resistance to changes of shape or volume, such as a sheet of paper or plastic strip, is evaluated in terms of standard colors." [http://en.wikipedia.org/wiki/Solid_%28state_of_matter%29 "Wikipedia", McGraw-Hill:McGraw-Hill_Dictionary_of_Scientific_and_Technical_Terms--4th_Ed]
is_a: MMO:0000327 ! colorimetry
created_by: JSmith
creation_date: 2013-02-12T14:57:02Z

[Term]
id: MMO:0000329
name: liquid phase colorimetry
def: "A technique by which the color of a sample following a reaction carried out in solution, that is, in a substance composed of molecules that can move about relatively freely and which exhibits a characteristic readiness to flow, little or no tendency to disperse, and relatively high incompressibility, is evaluated in terms of standard colors." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, American_Heritage:The_American_Heritage_Science_Dictionary_2005, McGraw-Hill:McGraw-Hill_Dictionary_of_Scientific_and_Technical_Terms--4th_Ed]
is_a: MMO:0000327 ! colorimetry
created_by: JSmith
creation_date: 2013-02-12T15:32:17Z

[Term]
id: MMO:0000330
name: peptide/protein analysis by liquid phase colorimetry
def: "Method of assessing the amount of one or more proteins (complex high molecular weight organic compounds containing carbon, hydrogen, oxygen, nitrogen, and sulfur consisting of alpha-amino acids joined by peptide linkages) or peptides (low molecular weight compounds composed of at least two amino acids joined by peptide linkages) in a solution, using a technique in which the color of that solution, usually after a chemical or enzymatic reaction, is compared to standard colors." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, McGraw-Hill:McGraw-Hill_Dictionary_of_Scientific_and_Technical_Terms--4th_Ed]
is_a: MMO:0000329 ! liquid phase colorimetry
created_by: JSmith
creation_date: 2013-02-12T15:46:22Z

[Term]
id: MMO:0000331
name: protein analysis by liquid phase colorimetry with spectrophotometric readout
def: "Method of assessing the amount of one or more proteins, complex high molecular weight organic compounds containing carbon, hydrogen, oxygen, nitrogen, and sulfur consisting of alpha-amino acids joined by peptide linkages, in a solution using a technique in which the color of that solution, usually after a chemical or enzymatic reaction, is evaluated based on its ability to alter the transmission of light at specific wavelengths in the visible spectrum, that is, to alter the transmission of a specific color of light, using a spectrophotometer." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, McGraw-Hill:McGraw-Hill_Dictionary_of_Scientific_and_Technical_Terms--4th_Ed, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000173 ! spectrophotometry
is_a: MMO:0000330 ! peptide/protein analysis by liquid phase colorimetry
created_by: JSmith
creation_date: 2013-02-12T16:00:26Z

[Term]
id: MMO:0000332
name: pyrogallol red-molybdate complex-based urine total protein analysis
def: "Method of assessing the total amount of protein, complex organic compounds containing carbon, hydrogen, oxygen, nitrogen, and sulfur consisting of alpha-amino acids joined by peptide linkages, in a specified sample of urine based upon measuring the shift in the absorption that occurs when a complex of pyrogallol red and molybdate binds to basic amino acid groups of protein molecules in the sample." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:3731450]
is_a: MMO:0000335 ! urine total protein analysis
is_a: MMO:0000423 ! urine protein colorimetric analysis
created_by: JSmith
creation_date: 2013-02-12T16:03:41Z

[Term]
id: MMO:0000333
name: protein analysis by liquid phase colorimetry with visual assessment
def: "Method of assessing the amount of one or more proteins, complex high molecular weight organic compounds containing carbon, hydrogen, oxygen, nitrogen, and sulfur consisting of alpha-amino acids joined by peptide linkages, in a solution using a technique in which the color of that solution, usually after a chemical or enzymatic reaction, is evaluated through the use of sight to compare the output with a standard color scale." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, McGraw-Hill:McGraw-Hill_Dictionary_of_Scientific_and_Technical_Terms--4th_Ed]
is_a: MMO:0000330 ! peptide/protein analysis by liquid phase colorimetry
created_by: JSmith
creation_date: 2013-02-12T19:27:20Z

[Term]
id: MMO:0000334
name: urine protein analysis
def: "Any method of assessing one or more proteins, complex organic compounds containing carbon, hydrogen, oxygen, nitrogen, and sulfur consisting of alpha-amino acids joined by peptide linkages, in a specified sample of urine, the fluid waste product excreted by the kidneys." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000147 ! urine analysis
created_by: JSmith
creation_date: 2013-02-12T19:55:35Z

[Term]
id: MMO:0000335
name: urine total protein analysis
def: "Any method of assessing the entire amount of protein, complex organic compounds containing carbon, hydrogen, oxygen, nitrogen, and sulfur consisting of alpha-amino acids joined by peptide linkages, in a sample of urine, the fluid waste product excreted by the kidneys." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000334 ! urine protein analysis
created_by: JSmith
creation_date: 2013-02-12T19:59:08Z

[Term]
id: MMO:0000336
name: urine microalbumin analysis
def: "Any method of assessing very low levels of albumin, the major blood plasma protein which is responsible for much of the plasma colloidal osmotic pressure and serves as a transport protein for large organic anions such as fatty acids and bilirubin, in a specified sample of urine, the fluid waste product excreted by the kidneys." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000406 ! urine albumin analysis
created_by: JSmith
creation_date: 2013-02-12T20:00:59Z

[Term]
id: MMO:0000337
name: echocardiography
def: "Method in which ultrasonic waves directed through the heart are reflected backward, or echoed, when they pass from one type of tissue to another, such as from cardiac muscle to blood, to create an image of the heart muscle and show the size, shape, and movement of the heart's valves and chambers as well as the flow of blood through the heart." [Gale:Gale_Encyclopedia_of_Medicine, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "cardiac echo" EXACT []
synonym: "ECHO" EXACT []
synonym: "ultrasonic cardiography" RELATED []
is_a: MMO:0000024 ! ultrasound method
created_by: JSmith
creation_date: 2013-02-12T21:19:37Z

[Term]
id: MMO:0000338
name: western blot
def: "A multistep process in which a mixture of proteins is separated by gel electrophoresis, that is, separation of ionic solutes based on differences in rate of migration in an applied electric field using a semisolid colloid such as agarose or acrylamide as the support medium, followed by transfer to a membrane, usually composed of nitrocellulose, nylon or polyvinylidene difluoride (PVDF) and detection of specific proteins by binding of tagged or labelled antibodies." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Western_blot "Wikipedia", ISBN:978-1416049982]
comment: term merged into 'western blot assay' (MMO:0000669)
is_obsolete: true
created_by: JSmith
creation_date: 2013-02-13T17:47:29Z

[Term]
id: MMO:0000340
name: Southern blot
def: "A multistep process in which a mixture of DNA (deoxyribonucleic acid) is separated by gel electrophoresis, that is, separation of ionic solutes based on differences in rate of migration in an applied electric field using a semisolid colloid such as agarose or acrylamide as the support medium, followed by transfer to a membrane such as nitrocellulose or nylon and detection of specific RNAs by hybridization of a tagged or labelled polynucleotide, usually a single DNA fragment with a specific, known sequence." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Southern_blot "Wikipedia", ISBN:978-1416049982]
is_a: MMO:0000100 ! gel electrophoresis
created_by: JSmith
creation_date: 2013-02-13T17:59:29Z

[Term]
id: MMO:0000341
name: ex vivo myography
def: "Use of a myograph to study muscle contraction after removal of the tissue from the body. A myograph is a device for quantifying contractile properties of muscles (e.g. force-length, force-velocity), generally through direct mechanical coupling to a force transducer, that is, an instrument which converts one form of energy, such as mechanical force, into another form, such as an electrical signal, for recording." [http://www.adinstruments.com/solutions/research/applications/wire-myography#overview "Website"]
is_a: MMO:0000207 ! tissue force analysis utilizing a force transducer
created_by: JSmith
creation_date: 2013-02-14T13:31:49Z

[Term]
id: MMO:0000342
name: wire myography
def: "A method which uses wires threaded through segments of isolated blood vessels and connected to a myograph, a device for quantifying contractile properties of muscles (e.g. force-length, force-velocity), generally through direct mechanical coupling to a force transducer (that is, an instrument which converts one form of energy, such as mechanical force, into another form, such as an electrical signal, for recording) to measure contraction in those arteries." [PMID:16028678]
is_a: MMO:0000341 ! ex vivo myography
created_by: JSmith
creation_date: 2013-02-14T16:27:25Z

[Term]
id: MMO:0000343
name: autopsy
def: "A postmortem examination of a body to determine the cause of death or the character and extent of changes produced by disease." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed]
is_a: MMO:0000000 ! measurement method
created_by: JSmith
creation_date: 2013-02-14T17:10:01Z

[Term]
id: MMO:0000344
name: necropsy
def: "A postmortem examination of the body of an animal to determine the cause of death or the character and extent of changes produced by disease." [Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed]
is_a: MMO:0000343 ! autopsy
created_by: JSmith
creation_date: 2013-02-14T17:20:02Z

[Term]
id: MMO:0000345
name: automated blood protein analysis
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the amount and/or composition of proteins, complex organic compounds containing carbon, hydrogen, oxygen, nitrogen, and sulfur consisting of alpha-amino acids joined by peptide linkages, in blood." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000179 ! automated blood analysis
created_by: JSmith
creation_date: 2013-02-14T17:46:35Z

[Term]
id: MMO:0000346
name: automated serum protein analysis
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the amount and/or composition of proteins, complex organic compounds containing carbon, hydrogen, oxygen, nitrogen, and sulfur consisting of alpha-amino acids joined by peptide linkages, in serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000345 ! automated blood protein analysis
is_a: MMO:0000554 ! automated serum analysis
created_by: JSmith
creation_date: 2013-02-14T17:56:09Z

[Term]
id: MMO:0000347
name: automated serum total protein analysis
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the entire amount of protein, the mix of complex organic compounds containing carbon, hydrogen, oxygen, nitrogen, and sulfur consisting of alpha-amino acids joined by peptide linkages, in serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [http://www.thefreedictionary.com/ "Multiple_Dictionaries"]
is_a: MMO:0000346 ! automated serum protein analysis
is_a: MMO:0000355 ! automated blood total protein analysis
created_by: JSmith
creation_date: 2013-02-14T17:58:05Z

[Term]
id: MMO:0000348
name: automated serum bicarbonate test
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the amount of bicarbonate, an anion of carbonic acid in which only one of the hydrogen atoms has been removed, in serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000556 ! automated serum electrolyte analysis
created_by: JSmith
creation_date: 2013-02-14T18:04:04Z

[Term]
id: MMO:0000349
name: automated blood albumin analysis
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure albumin, the major blood plasma protein which is responsible for much of the plasma colloidal osmotic pressure and serves as a transport protein for large organic anions such as fatty acids and bilirubin, in blood." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000345 ! automated blood protein analysis
created_by: JSmith
creation_date: 2013-02-20T17:17:33Z

[Term]
id: MMO:0000350
name: automated serum albumin analysis
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure albumin, the major blood plasma protein which is responsible for much of the plasma colloidal osmotic pressure and serves as a transport protein for large organic anions such as fatty acids and bilirubin, in serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000346 ! automated serum protein analysis
is_a: MMO:0000349 ! automated blood albumin analysis
created_by: JSmith
creation_date: 2013-02-20T17:26:51Z

[Term]
id: MMO:0000351
name: automated plasma albumin analysis
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure albumin, the major blood plasma protein which is responsible for much of the plasma colloidal osmotic pressure and serves as a transport protein for large organic anions such as fatty acids and bilirubin, in plasma, the fluid portion of the blood in which the particulate components are suspended." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000349 ! automated blood albumin analysis
is_a: MMO:0000352 ! automated plasma protein analysis
created_by: JSmith
creation_date: 2013-02-20T17:26:54Z

[Term]
id: MMO:0000352
name: automated plasma protein analysis
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the amount and/or composition of proteins, complex organic compounds containing carbon, hydrogen, oxygen, nitrogen, and sulfur consisting of alpha-amino acids joined by peptide linkages, in plasma, the fluid portion of the blood remaining after cells and platelets are removed." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000345 ! automated blood protein analysis
is_a: MMO:0000553 ! automated plasma analysis
created_by: JSmith
creation_date: 2013-02-20T17:30:44Z

[Term]
id: MMO:0000353
name: automated serum creatinine analysis
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the level of creatinine, the catabolic product of creatine, in serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [http://www.thefreedictionary.com/ "Multiple_Dictionaries", ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed]
is_a: MMO:0000168 ! automated blood creatinine analysis
is_a: MMO:0000271 ! serum creatinine analysis
is_a: MMO:0000554 ! automated serum analysis
created_by: JSmith
creation_date: 2013-02-20T17:40:54Z

[Term]
id: MMO:0000354
name: automated plasma creatinine analysis
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the level of creatinine, the catabolic product of creatine, in plasma, the fluid portion of the blood in which the particulate components are suspended." [http://www.thefreedictionary.com/--8th_Ed "Multiple_Dictionaries", ISBN:978-0323057479, Mosby:Mosbys_Manual_of_Diagnostic_and_Laboratory_Tests--4th_Ed]
is_a: MMO:0000168 ! automated blood creatinine analysis
is_a: MMO:0000306 ! plasma creatinine analysis
is_a: MMO:0000553 ! automated plasma analysis
created_by: JSmith
creation_date: 2013-02-20T17:40:58Z

[Term]
id: MMO:0000355
name: automated blood total protein analysis
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the entire amount of protein, the mix of complex organic compounds containing carbon, hydrogen, oxygen, nitrogen, and sulfur consisting of alpha-amino acids joined by peptide linkages, in blood." [http://www.thefreedictionary.com/ "Multiple_Dictionaries"]
is_a: MMO:0000345 ! automated blood protein analysis
created_by: JSmith
creation_date: 2013-02-20T17:51:36Z

[Term]
id: MMO:0000356
name: automated plasma total protein analysis
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the entire amount of protein, the mix of complex organic compounds containing carbon, hydrogen, oxygen, nitrogen, and sulfur consisting of alpha-amino acids joined by peptide linkages, in plasma, the fluid portion of the blood in which the particulate components are suspended." [http://www.thefreedictionary.com/ "Multiple_Dictionaries"]
is_a: MMO:0000352 ! automated plasma protein analysis
is_a: MMO:0000355 ! automated blood total protein analysis
created_by: JSmith
creation_date: 2013-02-20T17:55:19Z

[Term]
id: MMO:0000357
name: urine volume measurement method
def: "Any method by which the size of the three dimensional space occupied by a sample of urine, the fluid waste product excreted by the kidneys, is determined." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, American_Heritage:The_American_Heritage_Science_Dictionary_2005]
is_a: MMO:0000147 ! urine analysis
is_a: MMO:0000212 ! ex vivo volume measurement method
created_by: JSmith
creation_date: 2013-02-20T18:11:36Z

[Term]
id: MMO:0000358
name: automated urine protein analysis
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure protein, complex organic compounds containing carbon, hydrogen, oxygen, nitrogen, and sulfur consisting of alpha-amino acids joined by peptide linkages, in a sample of urine, the fluid waste product excreted by the kidneys." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000177 ! automated urine analysis
is_a: MMO:0000334 ! urine protein analysis
created_by: JSmith
creation_date: 2013-02-20T18:21:27Z

[Term]
id: MMO:0000359
name: automated urine total protein analysis
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the entire amount of protein, complex organic compounds containing carbon, hydrogen, oxygen, nitrogen, and sulfur consisting of alpha-amino acids joined by peptide linkages, in a sample of urine, the fluid waste product excreted by the kidneys." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000335 ! urine total protein analysis
is_a: MMO:0000358 ! automated urine protein analysis
created_by: JSmith
creation_date: 2013-02-20T18:22:55Z

[Term]
id: MMO:0000360
name: automated urine albumin analysis
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure albumin, the major blood plasma protein which is responsible for much of the plasma colloidal osmotic pressure and serves as a transport protein for large organic anions such as fatty acids and bilirubin, in urine, the fluid waste product excreted by the kidneys." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000358 ! automated urine protein analysis
is_a: MMO:0000406 ! urine albumin analysis
created_by: JSmith
creation_date: 2013-02-20T18:28:01Z

[Term]
id: MMO:0000361
name: treadmill method
def: "Any method that utilizes a device consisting of a continuous moving belt which allows a subject to walk or run while physically remaining in one place." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed]
synonym: "treadmill test" RELATED []
is_a: MMO:0000255 ! movement/behavior test apparatus method
created_by: JSmith
creation_date: 2013-02-21T15:00:19Z

[Term]
id: MMO:0000362
name: treadmill method with electric shock source
def: "A method that utilizes a device consisting of a continuous moving belt which allows a subject to walk or run while physically remaining in one place, containing an apparatus which delivers a relatively low voltage flow of electricity to the body if the subject leaves the belt." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, http://www.panlab.com/panlabWeb/Hardware/php/displayHard.php?nameHard=TREADMILL "Website"]
is_a: MMO:0000361 ! treadmill method
created_by: JSmith
creation_date: 2013-02-21T15:08:52Z

[Term]
id: MMO:0000363
name: dual-energy x-ray absorptiometry
def: "A scanning technique which directs alternating X-ray energy from two separate sources (high energy and low energy) towards bone at a set frequency. The amount of these x-rays that pass through the bone is measured for each beam and bone mineral density is determined based on the difference of the two transmitted X-ray beams." [http://www.medterms.com/script/main/art.asp?articlekey=24486 "Website"]
synonym: "bone densitometry" RELATED []
synonym: "bone density scanning" RELATED []
synonym: "DEXA" RELATED []
synonym: "DXA" RELATED []
is_a: MMO:0000383 ! absorptiometry
created_by: JSmith
creation_date: 2013-02-21T15:38:30Z

[Term]
id: MMO:0000364
name: quantitative computed tomography
def: "A computed tomography (CT) technique that measures bone mineral density (BMD) in either the axial or appendicular skeleton using a calibration standard to convert the Hounsfield Units (HU) of the CT image to BMD values. CT is a method of producing images of single tissue planes in which the emergent X-ray beam is measured by a scintillation counter and the electronic impulses are recorded on a magnetic disk and processed by a mini-computer for reconstruction display of the body in cross-section." [http://en.wikipedia.org/wiki/Quantitative_computed_tomography "Wikipedia", http://www.springerprotocols.com/Abstract/doi/10.1385/1-59259-366-6\:323 "Springer_Protocols", http://www.thefreedictionary.com/ "Multiple_Dictionaries"]
is_a: MMO:0000128 ! computed tomography
created_by: JSmith
creation_date: 2013-02-21T16:00:07Z

[Term]
id: MMO:0000365
name: in vivo peripheral quantitative computed tomography
def: "A computed tomography (CT) technique that uses a low radiation dose to measure bone mineral density (BMD) in the appendicular skeleton, utilizing a calibration standard ('phantoms') to convert the Hounsfield Units (HU) of the CT image to BMD values. CT is a method of producing images of single tissue planes in which the emergent X-ray beam is measured by a scintillation counter and the electronic impulses are recorded on a magnetic disk and processed by a mini-computer for reconstruction display of the body in cross-section." [http://en.wikipedia.org/wiki/Quantitative_computed_tomography "Wikipedia", http://www.springerprotocols.com/Abstract/doi/10.1385/1-59259-366-6\:323 "Springer_Protocols", http://www.thefreedictionary.com/ "Multiple_Dictionaries"]
comment: Peripheral quantitative computed tomography can be performed on excised bones as well as bones in vivo. This term, being in the "in vivo method" branch of the MMO, does not cover ex vivo usage of the technique. For that application please use the term "ex vivo peripheral quantitative computed tomography", MMO:0000367.
synonym: "in vivo pQCT" RELATED []
synonym: "pQCT" RELATED []
is_a: MMO:0000364 ! quantitative computed tomography
created_by: JSmith
creation_date: 2013-02-21T16:30:50Z

[Term]
id: MMO:0000366
name: ex vivo radiography
def: "Using X-rays or gamma rays to create records of the internal structures of an organ or other body part after removal from the body." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000027 ! ex vivo method
created_by: JSmith
creation_date: 2013-02-21T17:04:22Z

[Term]
id: MMO:0000367
name: ex vivo peripheral quantitative computed tomography
def: "A computed tomography (CT) technique that uses a low radiation dose to measure bone mineral density (BMD) of a bone after removal from the body and possibly after removal of the surrounding tissues such as the muscle, utilizing a calibration standard ('phantoms') to convert the Hounsfield Units (HU) of the CT image to BMD values. CT is a method of producing images of single tissue planes in which the emergent X-ray beam is measured by a scintillation counter and the electronic impulses are recorded on a magnetic disk and processed by a mini-computer for reconstruction display of the body in cross-section." [http://en.wikipedia.org/wiki/Quantitative_computed_tomography "Wikipedia", http://www.springerprotocols.com/Abstract/doi/10.1385/1-59259-366-6\:323 "Springer_Protocols", http://www.thefreedictionary.com/ "Multiple_Dictionaries"]
comment: Peripheral quantitative computed tomography can be performed on bones in vivo as well as excised bones. This term, being in the "ex vivo method" branch of the MMO, does not cover in vivo usage of the technique. For that application, please use the term "in vivo peripheral quantitative computed tomography", MMO:0000365.
synonym: "ex vivo pQCT" RELATED []
is_a: MMO:0000366 ! ex vivo radiography
created_by: JSmith
creation_date: 2013-02-21T17:08:34Z

[Term]
id: MMO:0000368
name: hemocytometer
def: "An instrument used for manual, microscopic counting of cells in suspension and consisting of a glass microscope slide with a rectangular indentation that creates a chamber. The chamber is engraved with a precise laser-etched grid of perpendicular lines and the depth of the chamber is standardized so that the volume of fluid and cells contained within a grid square and between the slide and the cover glass is known, allowing a count per volume to be determined." [http://en.wikipedia.org/wiki/Hemocytometer "Wikipedia"]
synonym: "haemacytometer" RELATED []
synonym: "haemocytometer" EXACT []
synonym: "hemacytometer" EXACT []
is_a: MMO:0000224 ! isolated cell counting method
created_by: JSmith
creation_date: 2013-02-21T17:26:14Z

[Term]
id: MMO:0000369
name: nitrite analysis by liquid phase colorimetry
def: "Method of assessing the amount of nitrite, the nitrogen oxoanion chemical formula NO2(-), in a solution using a technique in which the color of that solution, usually after a chemical or enzymatic reaction, is compared to a color standard. Measurement of nitrite is used to estimate nitric oxide (NO) production in biological systems." [http://www.mdpi.com/1424-8220/3/8/276/pdf "MDPI"]
synonym: "nitric oxide analysis by liquid phase colorimetry" RELATED []
is_a: MMO:0000329 ! liquid phase colorimetry
created_by: JSmith
creation_date: 2013-02-27T11:00:55Z

[Term]
id: MMO:0000370
name: nitrite analysis using the Griess reaction
def: "Method of assessing the amount of nitrite, the nitrogen oxoanion chemical formula NO2(-), in a solution by treating with a diazotizing reagent, e.g. sulfanilamide (SA), in acidic media to form a transient diazonium salt which is then allowed to react with a coupling reagent, N-naphthyl-ethylenediamine (NED), to form a stable azo compound with an intense purple color that absorbs light at 540 nm. Measurement of nitrite is used to estimate nitric oxide (NO) production in biological systems." [http://www.mdpi.com/1424-8220/3/8/276/pdf "MDPI"]
synonym: "Griess test" RELATED []
synonym: "Griess test for nitric oxide" RELATED []
synonym: "nitric oxide analysis using the Griess reaction" RELATED []
synonym: "nitrite analysis using the Griess reagent" RELATED []
is_a: MMO:0000369 ! nitrite analysis by liquid phase colorimetry
created_by: JSmith
creation_date: 2013-02-27T11:35:41Z

[Term]
id: MMO:0000371
name: ex vivo biological fluid analysis
def: "Any method to determine the nature, properties, or composition of a biological fluid, that is a liquid produced by a living organism, after that fluid has been removed or excreted from the body." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000027 ! ex vivo method
created_by: JSmith
creation_date: 2013-02-27T12:04:50Z

[Term]
id: MMO:0000372
name: exudate analysis
def: "Any method to determine the nature, properties, or composition of a fluid, often resulting from inflammation and with a high content of protein, cells and/or cellular debris, which has escaped from blood vessels and has been deposited in tissues or on tissue surfaces." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000371 ! ex vivo biological fluid analysis
created_by: JSmith
creation_date: 2013-02-27T12:19:30Z

[Term]
id: MMO:0000373
name: exudate nitrite analysis
def: "Any method to assess nitrite, the nitrogen oxoanion chemical formula NO2(-), in exudate, a fluid, often resulting from inflammation and with a high content of protein, cells and/or cellular debris, which has escaped from blood vessels and has been deposited in tissues or on tissue surfaces. Measurement of nitrite is used to estimate nitric oxide (NO) production in biological systems." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://www.mdpi.com/1424-8220/3/8/276/pdf "MDPI", ISBN:978-1416049982]
synonym: "exudate nitritic oxide analysis" RELATED []
is_a: MMO:0000372 ! exudate analysis
created_by: JSmith
creation_date: 2013-02-27T12:23:16Z

[Term]
id: MMO:0000374
name: urine nitrite analysis
def: "Any method to assess nitrite, the nitrogen oxoanion chemical formula NO2(-), in urine, the fluid waste product excreted by the kidneys. Measurement of nitrite is used to estimate nitric oxide (NO) production in biological systems." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, http://www.mdpi.com/1424-8220/3/8/276/pdf "MDPI"]
synonym: "urine nitritic oxide analysis" RELATED []
is_a: MMO:0000147 ! urine analysis
created_by: JSmith
creation_date: 2013-02-27T12:27:49Z

[Term]
id: MMO:0000375
name: blood nitrite analysis
def: "Any method to assess nitrite, the nitrogen oxoanion chemical formula NO2(-), in blood the fluid circulating through the heart, arteries, capillaries, and veins, carrying nutrients and oxygen to body cells, and removing waste products and carbon dioxide. Measurement of nitrite is used to estimate nitric oxide (NO) production in biological systems." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://www.mdpi.com/1424-8220/3/8/276/pdf "MDPI", ISBN:978-1416049982]
synonym: "blood nitritic oxide analysis" RELATED []
is_a: MMO:0000030 ! ex vivo blood analysis
created_by: JSmith
creation_date: 2013-02-27T12:28:33Z

[Term]
id: MMO:0000376
name: urine nitrite analysis using the Griess reaction
def: "Method of assessing the amount of nitrite, the nitrogen oxoanion chemical formula NO2(-), in a sample of urine, the fluid waste product excreted by the kidneys, by treating with a diazotizing reagent, e.g. sulfanilamide (SA), in acidic media to form a transient diazonium salt which is then allowed to react with a coupling reagent, N-naphthyl-ethylenediamine (NED), to form a stable azo compound with an intense purple color that absorbs light at 540 nm. Measurement of nitrite is used to estimate nitric oxide (NO) production in biological systems." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, http://www.mdpi.com/1424-8220/3/8/276/pdf "MDPI"]
synonym: "urine nitrite Griess test" RELATED []
synonym: "urine nitritic oxide analysis using the Griess reaction" RELATED []
synonym: "urine nitritic oxide Griess test" RELATED []
is_a: MMO:0000370 ! nitrite analysis using the Griess reaction
is_a: MMO:0000374 ! urine nitrite analysis
created_by: JSmith
creation_date: 2013-02-27T12:40:26Z

[Term]
id: MMO:0000377
name: exudate nitrite analysis using the Griess reaction
def: "Method of assessing the amount of nitrite, the nitrogen oxoanion chemical formula NO2(-), in exudate, a fluid, often resulting from inflammation and with a high content of protein, cells and/or cellular debris, which has escaped from blood vessels and has been deposited in tissues or on tissue surfaces, by treating a sample of exudate with a diazotizing reagent, e.g. sulfanilamide (SA), in acidic media to form a transient diazonium salt which is then allowed to react with a coupling reagent, N-naphthyl-ethylenediamine (NED), to form a stable azo compound with an intense purple color that absorbs light at 540 nm. Measurement of nitrite is used to estimate nitric oxide (NO) production in biological systems." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://www.mdpi.com/1424-8220/3/8/276/pdf "MDPI", ISBN:978-1416049982]
synonym: "exudate nitrite Griess test" RELATED []
synonym: "exudate nitritic oxide analysis using the Griess reaction" RELATED []
synonym: "exudate nitritic oxide Griess test" RELATED []
is_a: MMO:0000370 ! nitrite analysis using the Griess reaction
is_a: MMO:0000373 ! exudate nitrite analysis
created_by: JSmith
creation_date: 2013-02-27T12:46:53Z

[Term]
id: MMO:0000378
name: blood nitrite analysis using the Griess reaction
def: "Method of assessing the amount of nitrite, the nitrogen oxoanion chemical formula NO2(-), in blood the fluid circulating through the heart, arteries, capillaries, and veins, carrying nutrients and oxygen to body cells, and removing waste products and carbon dioxide, by treating a sample of blood with a diazotizing reagent, e.g. sulfanilamide (SA), in acidic media to form a transient diazonium salt which is then allowed to react with a coupling reagent, N-naphthyl-ethylenediamine (NED), to form a stable azo compound with an intense purple color that absorbs light at 540 nm. Measurement of nitrite is used to estimate nitric oxide (NO) production in biological systems." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://www.mdpi.com/1424-8220/3/8/276/pdf "MDPI", ISBN:978-1416049982]
synonym: "blood nitrite Griess test" RELATED []
synonym: "blood nitritic oxide analysis using the Griess reaction" RELATED []
synonym: "blood nitritic oxide Griess test" RELATED []
is_a: MMO:0000370 ! nitrite analysis using the Griess reaction
is_a: MMO:0000375 ! blood nitrite analysis
created_by: JSmith
creation_date: 2013-02-27T12:52:24Z

[Term]
id: MMO:0000379
name: flame atomic absorption spectrometry
def: "A spectroanalytical procedure for the quantitative determination of chemical elements employing the absorption of optical radiation (light) by free atoms in the gaseous state, in this case generated by a flame atomizer, e.g. an air-acetylene slot-type burner at 2300 degrees C or a nitrous oxide (N2O)-acetylene slot-type burner at 2700 degrees C." [http://en.wikipedia.org/wiki/Atomic_absorption_spectroscopy "Wikipedia", http://www.files.chem.vt.edu/chem-ed/spec/atomic/aa.html "Website"]
synonym: "flame AAS" RELATED []
synonym: "flame atomic absorption spectroscopy" EXACT []
is_a: MMO:0000232 ! atomic absorption spectrometry
created_by: JSmith
creation_date: 2013-02-27T14:58:06Z

[Term]
id: MMO:0000380
name: graphite furnace atomic absorption spectrometry
def: "A spectroanalytical procedure for the quantitative determination of chemical elements employing the absorption of optical radiation (light) by free atoms in the gaseous state, in this case generated by vaporization of the sample in an electrically heated apparatus coated with graphite, a soft hexagonally-crystallized allotrope of carbon." [http://en.wikipedia.org/wiki/Graphite_furnace_atomic_absorption "Wikipedia", http://www.files.chem.vt.edu/chem-ed/spec/atomic/aa.html "Website"]
synonym: "electrothermal atomic absorption spectrometry" RELATED []
synonym: "ETAAS" RELATED []
synonym: "GFAAS" RELATED []
synonym: "graphite furnace atomic absorption spectroscopy" EXACT []
is_a: MMO:0000232 ! atomic absorption spectrometry
created_by: JSmith
creation_date: 2013-02-27T15:01:32Z

[Term]
id: MMO:0000381
name: treadmill method with automated tracking
def: "A method that utilizes a device consisting of a continuous moving belt which allows a subject to walk or run while physically remaining in one place and connected to or incorporating a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to record output such as distance, speed, time, etc." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000361 ! treadmill method
created_by: JSmith
creation_date: 2013-02-27T15:23:04Z

[Term]
id: MMO:0000382
name: treadmill method with electric shock source and automated tracking
def: "A method that utilizes a device consisting of a continuous moving belt which allows a subject to walk or run while physically remaining in one place and incorporating both an apparatus which delivers a relatively low voltage flow of electricity to the body if the subject leaves the belt and a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to record output such as distance, speed, time, etc." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, http://www.panlab.com/panlabWeb/Hardware/php/displayHard.php?nameHard=TREADMILL "Website", Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000362 ! treadmill method with electric shock source
is_a: MMO:0000381 ! treadmill method with automated tracking
created_by: JSmith
creation_date: 2013-02-27T15:38:16Z

[Term]
id: MMO:0000383
name: absorptiometry
def: "A method whereby the radiation emitted by a radioisotope or other energy source is directed at a part of the body and the degree to which that radiation is dissipated within the tissue is measured." [Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed]
is_a: MMO:0000124 ! in vivo radiography
created_by: JSmith
creation_date: 2013-03-22T16:04:40Z

[Term]
id: MMO:0000384
name: dual photon absorptiometry
def: "A method used to measure, for instance, bone mineral content in the axial skeleton, particularly the lumbar spine, by comparing transmission of the two separate photoelectric energy peaks (gamma rays) emitted by gadolinium 153 through both soft and bone tissues. Because energy at the two peaks is dissipated differentially the soft-tissue component can be subtracted from the total to determine bone-specific absorption." [http://en.wikipedia.org/wiki/Gadolinium "Wikipedia", http://orthoinfo.aaos.org/topic.cfm?topic=a00413 "Website", Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed]
synonym: "DPA" RELATED []
is_a: MMO:0000383 ! absorptiometry
created_by: JSmith
creation_date: 2013-03-22T16:13:55Z

[Term]
id: MMO:0000385
name: single photon absorptiometry
def: "A scanning technique in which a single-energy photon beam, that is, a beam of electromagnetic radiation of a single energy, is passed through a material such as bone in order to measure its density." [http://orthoinfo.aaos.org/topic.cfm?topic=a00413 "Website", Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed]
synonym: "SPA" RELATED []
is_a: MMO:0000383 ! absorptiometry
created_by: JSmith
creation_date: 2013-03-22T17:20:47Z

[Term]
id: MMO:0000386
name: electroanalytical method
def: "Any analytical method in which a property such as concentration of an analyte is determined by measuring the potential (volts) and/or current (amperes) in an electrochemical cell containing the analyte." [http://en.wikipedia.org/wiki/Electroanalytical_Methods "Wikipedia"]
is_a: MMO:0000027 ! ex vivo method
created_by: JSmith
creation_date: 2013-06-07T16:53:19Z

[Term]
id: MMO:0000387
name: Clark-type oxygen electrode method
def: "A polarographic method for measuring oxygen (O2), the chemical element with atomic number 8 which is the essential agent in the respiration of plants and animals, in which a voltage is applied to a platinum electrode covered by a semipermiable membrane specific for oxygen resulting in the reduction of O2 according to the reaction [O2 + 4e- + 2 H2O --> 4 OH-] and the production of a measurable current in proportion to the oxygen tension in the measured sample." [Farlex:Farlex_Partner_Medical_Dictionary_2012, Google_Docs:Oxygen_Analyzers.doc, http://en.wikipedia.org/wiki/Clark_electrode "Wikipedia"]
synonym: "Clark electrode method" EXACT []
synonym: "dissolved oxygen electrode method" RELATED []
synonym: "oxygen membrane polarographic detector method" RELATED []
synonym: "oxygen sensor method" RELATED []
synonym: "pO2 electrode method" RELATED []
is_a: MMO:0000386 ! electroanalytical method
created_by: JSmith
creation_date: 2013-06-07T17:18:36Z

[Term]
id: MMO:0000388
name: enzymatic method
def: "A procedure or technique  by which a morphological or physiological state or property in a single individual or sample or a group of individuals or samples is assessed and a quantitative or qualitative value assigned, where that procedure is based on the action of one or more enzymes, proteins that catalyze chemical reactions of other substances without themselves being destroyed or altered upon completion of the reaction(s)." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:22654893]
synonym: "enzymatic analysis" RELATED []
synonym: "enzymatic assay" RELATED []
synonym: "enzyme-based analytical assay" RELATED []
is_a: MMO:0000027 ! ex vivo method
created_by: JSmith
creation_date: 2013-06-10T11:40:54Z

[Term]
id: MMO:0000389
name: enzymatic lipid assay
def: "A procedure or technique based on the action of one or more enzymes, proteins that catalyze chemical reactions of other substances without themselves being destroyed or altered upon completion of the reaction(s), used to assess one or more lipids, any of a structurally diverse group of organic compounds that are insoluble in water but soluble innonpolar solvents and that, among other biological functions, serve as a source of fuel and are an important constituent of cell structure." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "enzymatic lipid analysis" EXACT []
is_a: MMO:0000388 ! enzymatic method
created_by: JSmith
creation_date: 2013-06-10T12:08:51Z

[Term]
id: MMO:0000390
name: enzymatic cholesterol assay
def: "A procedure or technique based on the action of one or more enzymes, proteins that catalyze chemical reactions of other substances without themselves being destroyed or altered upon completion of the reaction(s), used to assess cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "enzymatic cholesterol analysis" EXACT []
is_a: MMO:0000389 ! enzymatic lipid assay
created_by: JSmith
creation_date: 2013-06-10T12:13:33Z

[Term]
id: MMO:0000391
name: enzymatic triglyceride assay
def: "A procedure or technique based on the action of one or more enzymes, proteins that catalyze chemical reactions of other substances without themselves being destroyed or altered upon completion of the reaction(s), used to assess triglyceride, a neutral fat compound that consists of three molecules of fatty acids bound with one molecule of glycerol and that is the usual storage form of lipids in animals." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed]
synonym: "enzymatic triglyceride analysis" EXACT []
is_a: MMO:0000389 ! enzymatic lipid assay
created_by: JSmith
creation_date: 2013-06-10T12:14:29Z

[Term]
id: MMO:0000392
name: pipette method
def: "A procedure or technique by which the size of the three dimensional space occupied by a liquid substance is ascertained using a pipette, a glass or transparent plastic tube used in measuring or transferring relatively small quantities of liquids." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "pipet method" EXACT []
synonym: "pipetting method" EXACT []
is_a: MMO:0000212 ! ex vivo volume measurement method
created_by: JSmith
creation_date: 2013-06-10T14:34:20Z

[Term]
id: MMO:0000393
name: calibrated Mohr pipette method
def: "A procedure or technique by which the size of the three dimensional space occupied by a liquid substance is ascertained using a calibrated Mohr pipette, a glass or transparent plastic tube with a series of graduated markings on it indicating volumes which has been checked and/or adjusted by comparison with a standard to ensure the accuracy of the measurement." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Mohr_pipette "Wikipedia", ISBN:978-1416049982]
synonym: "calibrated graduated pipette method" EXACT []
synonym: "calibrated Mohr pipet method" EXACT []
is_a: MMO:0000392 ! pipette method
created_by: JSmith
creation_date: 2013-06-10T14:47:37Z

[Term]
id: MMO:0000394
name: high-performance liquid chromatography
def: "A high pressure form of liquid column chromatography in which the solvent is forced through the column under high pressures of up to 400 atmospheres rather than being allowed to drip through the column under gravity. Liquid chomatography is a method of separating and identifying the components of a complex mixture by differential movement through a two-phase system, in which the movement is effected by a flow of a liquid (mobile phase) which percolates through an adsorbent (stationary phase)." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://www.chemguide.co.uk/analysis/chromatography/hplc.html "Website", ISBN:978-1416049982]
synonym: "high-pressure liquid chromatography" EXACT []
synonym: "HPLC" EXACT []
is_a: MMO:0000404 ! liquid column chromatography
created_by: JSmith
creation_date: 2013-06-20T16:54:33Z

[Term]
id: MMO:0000395
name: Richter feeding tube
def: "A capless, hollow, graduated cylinder designed to dispense liguid nourishment." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://www.dyets.com/blender.html "Website", ISBN:978-1416049982]
is_a: MMO:0000212 ! ex vivo volume measurement method
created_by: JSmith
creation_date: 2013-06-20T17:12:17Z

[Term]
id: MMO:0000396
name: isolated bone method
def: "The manner, procedure or technique by which a morphological or physiological state or property in a bone is assessed and a quantitative or qualitative value assigned. An isolated body part is a subdivision of the material or physical structure of an organism, such as an organ, extremity or tissue, after it has been removed from the body. Bone is the hard, rigid form of connective tissue constituting most of the skeleton of vertebrates and composed chiefly of calcium salts." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:22654893]
is_a: MMO:0000004 ! isolated body part method
created_by: JSmith
creation_date: 2013-07-09T11:05:20Z

[Term]
id: MMO:0000397
name: bone three-point bending test
def: "Isolated bone method in which the bone is held in a material testing apparatus consisting of three fittings (anvils or pins)--two supporting the bone from below and one positioned equidistant between them applying a specified force from above. The force, or load, is applied at a specified rate, usually until the bone breaks, and the displacement, i.e. the bending of the bone, resulting from the applied load is recorded." [http://www.instron.us/wa/acc_catalog/prod_list.aspx?cid=833&cname=3%20and%204%20Point%20Flexure%20Fixtures "Website", PMID:8274302]
synonym: "three-point load test" EXACT []
is_a: MMO:0000396 ! isolated bone method
created_by: JSmith
creation_date: 2013-07-09T11:29:13Z

[Term]
id: MMO:0000398
name: bone four-point bending test
def: "Isolated bone method in which the bone is held in a material testing apparatus consisting of four fittings (anvils or pins)--two supporting the bone from below and two positioned at a defined distance either side of the center applying a specified force from above. The force, or load, is applied at a specified rate, usually until the bone breaks, and the displacement, i.e. the bending of the bone, resulting from the applied load is recorded." [http://www.instron.us/wa/acc_catalog/prod_list.aspx?cid=833&cname=3%20and%204%20Point%20Flexure%20Fixtures "Website", PMID:8274302]
synonym: "four-point load test" EXACT []
is_a: MMO:0000396 ! isolated bone method
created_by: JSmith
creation_date: 2013-07-09T12:01:04Z

[Term]
id: MMO:0000399
name: bone compression test
def: "Isolated bone method in which the bone is held in a material testing apparatus between two plates or platens and a force or load is applied which presses or squeezes the plates together at a specified rate, often until fracture." [http://www.instron.us/wa/applications/test_types/compression.aspx "Website", PMID:8274302]
synonym: "compressive test" EXACT []
is_a: MMO:0000396 ! isolated bone method
created_by: JSmith
creation_date: 2013-07-09T12:33:08Z

[Term]
id: MMO:0000400
name: bone torsion test
def: "Isolated bone method in which the ends of the bone are embedded in blocks of a support material or otherwise secured and  subjected to an applied torque, that is a force applied in a twisting motion such that the two blocks rotate in parallel planes in opposite directlons relative to one another." [PMID:8274302]
is_a: MMO:0000396 ! isolated bone method
created_by: JSmith
creation_date: 2013-07-09T13:09:03Z

[Term]
id: MMO:0000401
name: visual assessment of in vivo video recording
def: "A procedure or technique in which a morphological or physiological state or property of a living body or in situ body part is evaluated, appraised or perceived through the sense of sight by watching a stored image-based record of the organism, body or body part, for example a videotape or a stored video file." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed, PMID:22654893]
synonym: "video monitoring" RELATED []
synonym: "videotape analysis" RELATED []
is_a: MMO:0000163 ! in vivo visual assessment
created_by: JSmith
creation_date: 2013-07-09T13:24:27Z

[Term]
id: MMO:0000402
name: Morris water maze method
def: "A method utilizing an experimental apparatus consisting of an open pool of water with a submerged escape platform, often with a set of visual cues such as colored shapes around the perimeter. An animal is placed in the water at a start location and must swim around the pool to find the platform." [http://en.wikipedia.org/wiki/Morris_water_maze "Wikipedia", PMID:17406317]
synonym: "Morris water maze procedure" RELATED []
synonym: "Morris water maze task" RELATED []
synonym: "Morris water navigation task" RELATED []
synonym: "Morris water navigation test" RELATED []
synonym: "MWM" RELATED []
is_a: MMO:0000257 ! movement/behavior test maze method
created_by: JSmith
creation_date: 2013-07-09T15:12:05Z

[Term]
id: MMO:0000403
name: enzymatic microassay
def: "A scaled down version of an analytical method based on the reaction(s) of one or more enzymes, proteins that catalyze chemical reactions of other substances without themselves being destroyed or altered upon completion of those reactions, to assess properties, such as concentration, of a target chemical in small volume samples." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "enzyme-based microanalysis" RELATED []
synonym: "micro-enzymatic assay" RELATED []
is_a: MMO:0000713 ! enzyme immunoassay
created_by: jsmith
creation_date: 2013-08-23T16:54:38Z

[Term]
id: MMO:0000404
name: liquid column chromatography
def: "A separation method in which a liquid mixture is applied to a tube or cylinder filled with a solid adsorbent, the stationary phase. The liquid phase passes through the column by either gravity or  external pressure during which individual components adsorb to the stationary phase based on their chemicophysical properties and the properties of the liquid and stationary phases of the column." [http://orgchem.colorado.edu/Technique/Procedures/Columnchrom/Columnchrom.html "Website", http://www.onelook.com/?w=column&ls=a "WordNet_3_0"]
synonym: "liquid-solid chromatography" RELATED []
is_a: MMO:0000468 ! column chromatography
created_by: jsmith
creation_date: 2013-08-23T17:14:31Z

[Term]
id: MMO:0000405
name: implanted wire electrode recording method
def: "A procedure or technique in which a wire electrode, a thread-like filament of metal for conducting an electrical current, is inserted into a specified location within the body, such as in or on a central or peripheral nerve, in order to monitor and record electrical activity." [Mosby:Mosbys_Medical_Dictionary--8th_Ed, Webster:Random_House_Kernerman_Websters_College_Dictionary_2010]
is_a: MMO:0000001 ! electrical potential recording method
created_by: jsmith
creation_date: 2013-08-23T18:20:44Z

[Term]
id: MMO:0000406
name: urine albumin analysis
def: "Any method of assessing the amount of albumin, the major blood plasma protein which is responsible for much of the plasma colloidal osmotic pressure and serves as a transport protein for large organic anions such as fatty acids and bilirubin, in a specified sample of urine, the fluid waste product excreted by the kidneys." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000334 ! urine protein analysis
created_by: JSmith
creation_date: 2013-09-20T16:40:13Z

[Term]
id: MMO:0000407
name: ex vivo photography
def: "The process of producing images by the action of radiant energy and especially light on a sensitive surface such as film or an optical sensor, of a part of an organism, such as an organ, tissue, or cell, after removal from the body." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed]
synonym: "ex vivo photodocumentation method" RELATED []
synonym: "photography of ex vivo subject" EXACT []
is_a: MMO:0000027 ! ex vivo method
created_by: JSmith
creation_date: 2013-09-27T17:34:07Z

[Term]
id: MMO:0000408
name: in vivo photography
def: "The process of producing images of an entire living organism, or of a part of a living organism such as an organ or tissue recorded in situ, by the action of radiant energy and especially light on a sensitive surface such as film or an optical sensor." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed]
synonym: "in vivo photodocumentation method" RELATED []
synonym: "photography of in vivo subject" EXACT []
is_a: MMO:0000026 ! in vivo method
created_by: JSmith
creation_date: 2013-09-27T17:35:36Z

[Term]
id: MMO:0000409
name: in vivo photography with digital image analysis
def: "The process of producing images of an entire living organism, or of a part of a living organism such as an organ or tissue recorded in situ, by the action of radiant energy and especially light on a sensitive surface such as film or an optical sensor followed by use of computer software to analyze or assist in the analysis of the resulting images." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed]
synonym: "in vivo photodocumentation  with digital image analysis" RELATED []
synonym: "photography of in vivo subject  with digital image analysis" EXACT []
is_a: MMO:0000408 ! in vivo photography
created_by: JSmith
creation_date: 2013-09-27T17:40:46Z

[Term]
id: MMO:0000410
name: ex vivo photography with digital image analysis
def: "The process of producing images by the action of radiant energy and especially light on a sensitive surface such as film or an optical sensor, of a part of an organism, such as an organ, tissue, or cell, after removal from the body, followed by use of computer software to analyze or assist in the analysis of the resulting images." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Merriam-Webster:Merriam-Websters_Online_Dictionary--11th_Ed]
synonym: "ex vivo photodocumentation  with digital image analysis" RELATED []
synonym: "photography of ex vivo subject  with digital image analysis" EXACT []
is_a: MMO:0000407 ! ex vivo photography
created_by: JSmith
creation_date: 2013-09-27T17:43:05Z

[Term]
id: MMO:0000411
name: tilting plane test
def: "A method which utilizes a platform that can be inclined, i.e., the position of which can be made to deviate from the horizontal, at or through a series of specified angles." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed]
synonym: "inclined plane test" EXACT []
synonym: "inclined platform test" RELATED []
synonym: "tilting platform test" EXACT []
is_a: MMO:0000588 ! balance, coordination or strength assessment method
created_by: JSmith
creation_date: 2013-09-30T13:35:58Z

[Term]
id: MMO:0000412
name: moving tilting plane test
def: "A method which utilizes a platform that can be inclined, i.e., the position of which can be made to deviate from the horizontal, in which the angle of inclination is continuously either increased or decreased and measurements are made while the platform is in motion." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, PMID:7582826]
synonym: "moving inclined plane test" EXACT []
synonym: "moving inclined platform test" RELATED []
synonym: "moving tilting platform test" EXACT []
is_a: MMO:0000411 ! tilting plane test
created_by: JSmith
creation_date: 2013-09-30T13:38:00Z

[Term]
id: MMO:0000413
name: stationary tilting plane test
def: "A method which utilizes a platform that can be inclined, i.e., the position of which can be made to deviate from the horizontal, in which the angle of inclination is either increased or decreased in fixed increments and measurements are made while the platform is not moving." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, PMID:7582826]
synonym: "stationary inclined plane test" EXACT []
synonym: "stationary inclined platform test" RELATED []
synonym: "stationary tilting platform test" EXACT []
is_a: MMO:0000411 ! tilting plane test
created_by: JSmith
creation_date: 2013-09-30T13:38:03Z

[Term]
id: MMO:0000414
name: V-shaped trough test
def: "A method in which a subject is placed, for example on its back, in an apparatus with two inclined sides that come to a point at the bottom forming a narrow open container with a triangular cross-section." [Collins:Collins_Online_English_Dictionary]
is_a: MMO:0000254 ! body movement/behavior method
created_by: JSmith
creation_date: 2013-09-30T14:15:30Z

[Term]
id: MMO:0000415
name: in vivo light microscopy
def: "A method performed in or on a living body, for example, a procedure performed on an organ in situ or on the entire living organism, consisting of the examination or observation of material using a light microscope, an optical instrument that employs visible light (electromagnetic radiation with wavelengths between approximately 390 and 700 nm) processed through a lens or a combination of lenses to produce magnified images." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Visible_spectrum "Wikipedia", ISBN:978-1416049982]
is_a: MMO:0000743 ! in vivo microscopy
created_by: JSmith
creation_date: 2013-09-30T15:36:51Z

[Term]
id: MMO:0000416
name: in vivo television microscopy
synonym: "clinical television microscopy" RELATED []
is_a: MMO:0000415 ! in vivo light microscopy
created_by: JSmith
creation_date: 2013-09-30T16:35:50Z

[Term]
id: MMO:0000417
name: in vivo stereo light microscopy
def: "Examination or observation of material, performed in or on a living body, for example, a procedure performed on an organ in situ or on the entire living organism, which employs a stereo light microscope, an optical instrument that uses visible light (electromagnetic radiation with wavelengths between approximately 390 and 700 nm) processed through a dual lens system, arranged in such a way that for the observer each eye or for a recording device each optical input receives a magnified image from a separate lens, generating a three-dimensional view." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://www.dissectingmicroscope.com/what-is-a-dissecting-microscope.html "Website", ISBN:978-1416049982]
is_a: MMO:0000415 ! in vivo light microscopy
created_by: JSmith
creation_date: 2013-09-30T16:51:11Z

[Term]
id: MMO:0000418
name: ex vivo stereo light microscopy
def: "Examination or observation of material, performed outside the living body, which employs a stereo light microscope, an optical instrument that uses visible light (electromagnetic radiation with wavelengths between approximately 390 and 700 nm) processed through a dual lens system, arranged in such a way that for the observer each eye or for a recording device each optical input receives a magnified image from a separate lens, generating a three-dimensional view." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://www.dissectingmicroscope.com/what-is-a-dissecting-microscope.html "Website", ISBN:978-1416049982]
is_a: MMO:0000111 ! ex vivo light microscopy
created_by: JSmith
creation_date: 2013-09-30T16:52:36Z

[Term]
id: MMO:0000419
name: ex vivo stereo light microscopy with digital image analysis
def: "Examination or observation of material, performed outside the living body, which incorporates use of stereo light microscopy to produce picture files stored as data expressed in a discrete numerical form, followed by use of computer software to evaluate these resulting microscopic images. Stereo light microscopy is a method which employs a stereo light microscope, an optical instrument that uses visible light (electromagnetic radiation with wavelengths between approximately 390 and 700 nm) processed through a dual lens system, arranged in such a way that for the recording device each optical input receives a magnified image from a separate lens, generating a three-dimensional view." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Visible_spectrum "Wikipedia", http://www.dissectingmicroscope.com/what-is-a-dissecting-microscope.html "Website", ISBN:978-1416049982]
is_a: MMO:0000220 ! ex vivo light microscopy with digital image analysis
is_a: MMO:0000418 ! ex vivo stereo light microscopy
created_by: JSmith
creation_date: 2013-11-12T14:08:54Z

[Term]
id: MMO:0000420
name: in vivo stereo light microscopy with digital image analysis
def: "Examination or observation of material, performed in or on a living body, for example, a procedure performed on an organ in situ or on the entire living organism, which incorporates use of stereo light microscopy to produce picture files stored digitally, that is, as data expressed in a discrete numerical form, followed by use of computer software to evaluate these resulting microscopic images. Stereo light microscopy is a method which employs a stereo light microscope, an optical instrument that uses visible light (electromagnetic radiation with wavelengths between approximately 390 and 700 nm) processed through a dual lens system, arranged in such a way that for the recording device each optical input receives a magnified image from a separate lens, generating a three-dimensional view." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Visible_spectrum "Wikipedia", http://www.dissectingmicroscope.com/what-is-a-dissecting-microscope.html "Website", ISBN:978-1416049982]
is_a: MMO:0000417 ! in vivo stereo light microscopy
is_a: MMO:0000421 ! in vivo light microscopy with digital image analysis
created_by: JSmith
creation_date: 2013-11-12T14:15:46Z

[Term]
id: MMO:0000421
name: in vivo light microscopy with digital image analysis
def: "A method performed in or on a living body, for example, a procedure performed on an organ in situ or on the entire living organism, which incorporates use of light microscopy to produce picture files stored as data expressed in a discrete numerical form, followed by use of computer software to evaluate these resulting microscopic images. Light microscopy is the examination or observation of material through a light microscope, an optical instrument that uses visible light (electromagnetic radiation with wavelengths between approximately 390 and 700 nm) processed through a lens or a combination of lenses to produce magnified images." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Visible_spectrum "Wikipedia", http://www.answers.com "Website", ISBN:978-1416049982]
is_a: MMO:0000415 ! in vivo light microscopy
created_by: JSmith
creation_date: 2013-11-12T14:23:04Z

[Term]
id: MMO:0000422
name: ex vivo light microscopy with immunohistochemistry and digital image analysis
def: "A method performed outside the living body, e.g., on isolated tissue, which incorporates use of light microscopy and immunohistochemistry to produce picture files stored as data expressed in a discrete numerical form, followed by use of computer software to evaluate these resulting microscopic images. Light microscopy is the examination or observation of material through a light microscope, an optical instrument that uses visible light (electromagnetic radiation with wavelengths between approximately 390 and 700 nm) processed through a lens or a combination of lenses to produce magnified images. Immunohistochemistry is the microscopic localization of specific antigens in tissues by staining with antibodies labeled with fluorescent or pigmented material." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Visible_spectrum "Wikipedia", http://www.answers.com "Website", ISBN:978-1416049982]
is_a: MMO:0000538 ! ex vivo light microscopy with immunohistochemistry
created_by: JSmith
creation_date: 2013-11-12T14:39:39Z

[Term]
id: MMO:0000423
name: urine protein colorimetric analysis
def: "Any method of assessing the amount or composition of protein, complex organic compounds containing carbon, hydrogen, oxygen, nitrogen, and sulfur consisting of alpha-amino acids joined by peptide linkages, in a sample of urine, the fluid waste product excreted by the kidneys, through the use of colorimetry. Colorimetry is any technique by which the color of an unknown, that is, the color of a sample, is evaluated in terms of the color(s) of a standard or a series of standards. The technique may be visual, photoelectric, or indirect by means of spectrophotometry." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000334 ! urine protein analysis
created_by: JSmith
creation_date: 2013-11-12T15:56:12Z

[Term]
id: MMO:0000424
name: bicinchoninic acid protein assay
def: "The BCA protein assay combines the protein-induced biuret reaction in which peptide bonds in the protein reduce Cu2+ ions to Cu+ in a reaction proportional to the amount of protein present, followed by chelation of bicinchoninic acid molecules with Cu+ ions, forming a purple-colored product which can be quantitated by spectrophotometry, i.e., based on the ability of the solution to alter the transmission of light at specific wavelengths in the visible spectrum, that is, to alter the transmission of a specific color of light." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Bicinchoninic_acid_assay "Wikipedia", http://www.piercenet.com/browse.cfm?fldID=876562B0-5056-8A76-4E0C-B764EAB3A339 "Website", ISBN:978-1416049982, McGraw-Hill:McGraw-Hill_Dictionary_of_Scientific_and_Technical_Terms--4th_Ed]
synonym: "BCA protein assay" RELATED []
is_a: MMO:0000331 ! protein analysis by liquid phase colorimetry with spectrophotometric readout
created_by: JSmith
creation_date: 2013-11-12T17:03:03Z

[Term]
id: MMO:0000425
name: Lowry protein assay
def: "The Lowry assay is an enhanced biuret test involving copper chelation chemistry to assess the amount of protein, any of a group of complex organic compounds containing carbon, hydrogen, oxygen, nitrogen, and sulfur consisting of alpha-amino acids joined by peptide linkages, in a specified sample. Following the Folin-Ciocalteu reaction, the reduced Folin reagent is quantitated by spectrophotometry, i.e., based on the ability of the solution to alter the transmission of light at specific wavelengths in the visible spectrum, that is, to alter the transmission of a specific color of light." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Lowry_protein_assay "Wikipedia", http://www.piercenet.com/browse.cfm?fldID=876562B0-5056-8A76-4E0C-B764EAB3A339 "Website", ISBN:978-1416049982, McGraw-Hill:McGraw-Hill_Dictionary_of_Scientific_and_Technical_Terms--4th_Ed]
is_a: MMO:0000331 ! protein analysis by liquid phase colorimetry with spectrophotometric readout
created_by: JSmith
creation_date: 2013-11-12T17:06:07Z

[Term]
id: MMO:0000426
name: Bradford protein assay
def: "The Bradford assay of protein concentration is based on an absorbance shift of the dye Coomassie Brilliant Blue G-250. In the acidic environment of the assay, protein binds to the Coomassie dye, resulting in a shift from reddish/brown to blue in the color of the dye, which can be quantitated by spectrophotometry, i.e., based on the ability of the solution to alter the transmission of light at specific wavelengths in the visible spectrum, that is, to alter the transmission of a specific color of light. The binding of the dye to the protein stabilizes the blue anionic form and the increase of absorbance at 595 nm is proportional to the amount of bound dye, and thus to the amount (concentration) of protein present in the sample." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Bradford_protein_assay "Wikipedia", http://www.piercenet.com/browse.cfm?fldID=876562B0-5056-8A76-4E0C-B764EAB3A339 "Website", ISBN:978-1416049982, McGraw-Hill:McGraw-Hill_Dictionary_of_Scientific_and_Technical_Terms--4th_Ed]
synonym: "Coomassie dye protein assay" EXACT []
is_a: MMO:0000331 ! protein analysis by liquid phase colorimetry with spectrophotometric readout
created_by: JSmith
creation_date: 2013-11-12T17:06:12Z

[Term]
id: MMO:0000427
name: plasma total protein analysis
def: "A method to determine the entire amount of all proteins, any of a group of complex organic compounds containing carbon, hydrogen, oxygen, nitrogen, and sulfur consisting of alpha-amino acids joined by peptide linkages, in plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, Webster:Random_House_Kernerman_Websters_College_Dictionary_2010]
is_a: MMO:0000443 ! blood total protein analysis
created_by: JSmith
creation_date: 2013-11-12T17:27:57Z

[Term]
id: MMO:0000428
name: serum total protein analysis
def: "A method to determine the entire amount of all proteins, any of a group of complex organic compounds containing carbon, hydrogen, oxygen, nitrogen, and sulfur consisting of alpha-amino acids joined by peptide linkages, in serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Webster:Random_House_Kernerman_Websters_College_Dictionary_2010]
is_a: MMO:0000443 ! blood total protein analysis
created_by: JSmith
creation_date: 2013-11-12T17:30:05Z

[Term]
id: MMO:0000429
name: blood enzyme activity assay
def: "Any method which quantifies the catalytic effect exerted by an enzyme, a protein that acts as a catalyst, increasing the rate at which a chemical reaction occurs without itself being destroyed or altered upon completion of the reaction, in blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed]
synonym: "blood enzyme activity analysis" EXACT []
synonym: "blood enzyme activity test" EXACT []
is_a: MMO:0000166 ! blood protein analysis
is_a: MMO:0000444 ! enzyme or transport activity assay
created_by: JSmith
creation_date: 2013-11-13T10:42:42Z

[Term]
id: MMO:0000430
name: blood renin activity assay
def: "A method which quantifies the catalytic effect exerted by renin in a specified sample of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. Renin is a proteolytic enzyme synthesized, stored, and secreted by the juxtaglomerular cells of the kidney; it plays a role in regulation of blood pressure by catalyzing the conversion of angiotensinogen to angiotensin I." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed]
synonym: "blood renin activity analysis" EXACT []
synonym: "blood renin activity test" EXACT []
is_a: MMO:0000429 ! blood enzyme activity assay
created_by: JSmith
creation_date: 2013-11-13T10:44:23Z

[Term]
id: MMO:0000431
name: plasma renin activity assay
def: "A method which quantifies the catalytic effect exerted by renin in a specified sample of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. Renin is a proteolytic enzyme synthesized, stored, and secreted by the juxtaglomerular cells of the kidney; it plays a role in regulation of blood pressure by catalyzing the conversion of angiotensinogen to angiotensin I." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed]
synonym: "plasma renin activity analysis" EXACT []
synonym: "plasma renin activity test" EXACT []
is_a: MMO:0000430 ! blood renin activity assay
created_by: JSmith
creation_date: 2013-11-13T10:45:41Z

[Term]
id: MMO:0000432
name: serum renin activity assay
def: "A method which quantifies the catalytic effect exerted by renin in a specified sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. Renin is a proteolytic enzyme synthesized, stored, and secreted by the juxtaglomerular cells of the kidney; it plays a role in regulation of blood pressure by catalyzing the conversion of angiotensinogen to angiotensin I." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "serum renin activity analysis" EXACT []
synonym: "serum renin activity test" EXACT []
is_a: MMO:0000430 ! blood renin activity assay
created_by: JSmith
creation_date: 2013-11-13T10:45:43Z

[Term]
id: MMO:0000433
name: urine electrolyte analysis
def: "A method which assesses the amount, proportions or properties of one or more electrolytes, any of various ions required by cells to regulate the electric charge and flow of water molecules across the cell membrane, in urine, the fluid waste product excreted by the kidneys." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007]
is_a: MMO:0000147 ! urine analysis
created_by: JSmith
creation_date: 2013-11-13T11:01:51Z

[Term]
id: MMO:0000434
name: urine sodium analysis
def: "A method which assesses the amount, proportions or properties of sodium in urine, the fluid waste product excreted by the kidneys. Sodium, the chemical element with atomic number 11 that in its ionic form has lost one electron, forming a cation with a charge of +1, is the chief cation of extracellular body fluids." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "urine Na+ analysis" RELATED []
synonym: "urine sodium ion analysis" EXACT []
is_a: MMO:0000433 ! urine electrolyte analysis
created_by: JSmith
creation_date: 2013-11-13T11:19:45Z

[Term]
id: MMO:0000435
name: urine potassium analysis
def: "A method which assesses the amount, proportions or properties of potassium in urine, the fluid waste product excreted by the kidneys. Potassium, the chemical element with atomic number 19 that in its ionic form has lost one electron, forming a cation with a charge of +1, is the chief cation of intracellular fluid." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "urine K+ analysis" RELATED []
synonym: "urine potassium ion analysis" EXACT []
is_a: MMO:0000433 ! urine electrolyte analysis
created_by: JSmith
creation_date: 2013-11-13T11:19:49Z

[Term]
id: MMO:0000436
name: bromocresol green-based urine albumin analysis with spectrophotometric readout
def: "A method of assessing the amount of albumin, the major blood plasma protein which is responsible for much of the plasma colloidal osmotic pressure and which serves as a transport protein for large organic anions such as fatty acids and bilirubin, in a specified sample of urine, the fluid waste product excreted by the kidneys. This method uses a technique in which the dye bromocresol green is incubated with the sample and the resulting color change is evaluated based on the ability of the solution to alter the transmission of light at specific wavelengths in the visible spectrum, that is, to alter the transmission of a specific color of light. Bromocresol green is a dye of the triphenylmethane family that forms a colored complex specifically with albumin. The intensity of the color is directly proportional to the albumin concentration in the sample." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Bromocresol_green "Wikipedia", http://www.usbio.net/item/A1309-50 "Website", ISBN:978-1416049982, McGraw-Hill:McGraw-Hill_Dictionary_of_Scientific_and_Technical_Terms--4th_Ed]
synonym: "BCG-based urine albumin analysis with spectrophotometric readout" RELATED []
is_a: MMO:0000331 ! protein analysis by liquid phase colorimetry with spectrophotometric readout
is_a: MMO:0000406 ! urine albumin analysis
is_a: MMO:0000423 ! urine protein colorimetric analysis
created_by: JSmith
creation_date: 2013-11-13T11:57:18Z

[Term]
id: MMO:0000437
name: immunodiffusion assay
def: "Any technique involving diffusion of antigen and/or antibody through a semisolid medium, resulting in a precipitin reaction, i.e. in the formation of precipitation lines in the medium around or between the wells in which the sample(s) were placed. A precipitin reaction is a specific interaction between an antibody and a soluble antigen in which the antibody specifically aggregates the macromolecular antigen to give a visible precipitate." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed]
is_a: MMO:0000098 ! immunoassay
created_by: JSmith
creation_date: 2013-11-13T14:37:17Z

[Term]
id: MMO:0000438
name: Ouchterlony double immunodiffusion assay
def: "A technique for detecting antibody-antigen interactions, where antigens and antibodies are placed into separate wells cut into a gel matrix and allowed to diffuse towards each other. Where the diffusion fronts meet, if an antibody recognizes an antigen, they will bind, forming an immune complex. The immune complex precipitates in the gel to give a visible white line." [http://en.wikipedia.org/wiki/Ouchterlony_double_immunodiffusion "Wikipedia", http://www.piercenet.com/product/immunodiffusion-plates "Website"]
synonym: "agar gel double immunodiffusion" RELATED []
synonym: "passive double immunodiffusion" RELATED []
is_a: MMO:0000437 ! immunodiffusion assay
created_by: JSmith
creation_date: 2013-11-13T14:40:32Z

[Term]
id: MMO:0000439
name: radial immunodiffusion assay
def: "A technique used to determine the quantity of an antigen by measuring the diameters of circles of precipitin complexes surrounding samples of the antigen that mark the boundary between the antigen and an antibody suspended in a gel. Antigen diffuses into the gel matrix containing a specific antibody and a ring of precipitate is formed, the diameter of which is directly proportional to the concentration of the antigen. Precipitin is an antibody that has specifically aggregated a macromolecular antigen to give a visible precipitate." [http://en.wikipedia.org/wiki/Radial_immunodiffusion "Wikipedia", Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed]
synonym: "Mancini immunodiffusion" RELATED []
synonym: "Mancini method" RELATED []
synonym: "single radial immunodiffusion assay" EXACT []
is_a: MMO:0000437 ! immunodiffusion assay
created_by: JSmith
creation_date: 2013-11-13T15:01:23Z

[Term]
id: MMO:0000440
name: reverse radial immunodiffusion assay
def: "A technique used to determine the quantity of an antibody in a sample by measuring the diameters of circles of precipitin complexes surrounding a well in a gel such as agar in which the sample is placed. Antibody diffuses into a gel matrix containing a specific antigen and a ring of precipitate is formed, the diameter of which is directly proportional to the concentration of the antibody in the sample. Precipitin is an antibody that has specifically aggregated a macromolecular antigen to give a visible precipitate." [http://en.wikipedia.org/wiki/Radial_immunodiffusion "Wikipedia", PMID:6797098, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed]
synonym: "reversed single radial immunodiffusion test" EXACT []
is_a: MMO:0000437 ! immunodiffusion assay
created_by: JSmith
creation_date: 2013-11-13T15:02:47Z

[Term]
id: MMO:0000441
name: bioassay
def: "Any method of determining the concentration, relative activity, or effects of a biologically active substance in a sample by comparing its effect on an organism, on an isolated tissue or on isolated cells in culture, with that of a reference standard." [MESH:D001681, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed]
synonym: "biological assay" EXACT []
synonym: "biological standardization" RELATED []
synonym: "biologic assay" EXACT []
is_a: MMO:0000027 ! ex vivo method
created_by: JSmith
creation_date: 2013-11-13T15:35:53Z

[Term]
id: MMO:0000442
name: cell proliferation bioassay
def: "A method of determining the concentration, relative activity or effects of a biologically active substance in a sample based on the effect of the sample on the reproduction or multiplication of cells, especially of cells which depend for their viability and/or reproduction on a particular substance of interest. The amount or activity of that substance in the sample is calculated by measuring the effect of the sample on the test cell culture compared with the effect of a reference standard." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, MESH:D001681, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed]
is_a: MMO:0000502 ! cell-based bioassay
created_by: JSmith
creation_date: 2013-11-13T16:26:56Z

[Term]
id: MMO:0000443
name: blood total protein analysis
def: "A method to determine the entire amount of all proteins, any of a group of complex organic compounds containing carbon, hydrogen, oxygen, nitrogen, and sulfur consisting of alpha-amino acids joined by peptide linkages, in blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Webster:Random_House_Kernerman_Websters_College_Dictionary_2010]
is_a: MMO:0000166 ! blood protein analysis
created_by: JSmith
creation_date: 2013-11-18T12:17:57Z

[Term]
id: MMO:0000444
name: enzyme or transport activity assay
def: "A procedure or technique performed outside the living body by which the catalytic activity of an enzyme (a protein that catalyzes chemical reactions of other substances without itself being destroyed or altered upon completion of the reactions) or activity of a transport molecule or complex is assessed and a quantitative or qualitative value assigned." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, https://en.wikipedia.org/wiki/Na%2B/K%2B-ATPase, https://en.wikipedia.org/wiki/Na-K-Cl_cotransporter]
xref: PMID:12887131
xref: PMID:3611769
is_a: MMO:0000027 ! ex vivo method
created_by: JSmith
creation_date: 2013-12-20T10:39:06Z

[Term]
id: MMO:0000445
name: blood cell counting method
def: "Any method, manual or automated, by which the number of cells in a sample of blood assessed and a value assigned." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:22654893]
is_a: MMO:0000030 ! ex vivo blood analysis
created_by: JSmith
creation_date: 2013-12-20T10:47:31Z

[Term]
id: MMO:0000446
name: manual blood cell counting method
def: "A method performed by hand, i.e., by a human and not by an automated machine, by which the number of cells in a sample of blood assessed and a value assigned." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:22654893]
is_a: MMO:0000445 ! blood cell counting method
created_by: JSmith
creation_date: 2013-12-20T10:56:37Z

[Term]
id: MMO:0000447
name: manual hemocytometer-based blood cell counting method
def: "A method performed by which a human uses a hemocytometer to assess the number of cells in a sample of blood and assign a value. A hemocytometer is an instrument used for manual, microscopic counting of cells in suspension and consisting of a glass microscope slide with a rectangular indentation that creates a chamber. The chamber is engraved with a precise laser-etched grid of perpendicular lines and the depth of the chamber is standardized so that the volume of fluid and cells contained within a grid square and between the slide and the cover glass is known, allowing a count per volume to be determined." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Hemocytometer "Wikipedia", ISBN:978-1416049982, PMID:22654893]
is_a: MMO:0000368 ! hemocytometer
is_a: MMO:0000446 ! manual blood cell counting method
created_by: JSmith
creation_date: 2013-12-20T11:01:29Z

[Term]
id: MMO:0000448
name: computer-aided tensile strength and compression test
def: "This is a test done by a machine physically interacting with isolated bone. The machine control and data readout is performed by computer connected to the machine." [RGD:SJL]
is_a: MMO:0000396 ! isolated bone method
created_by: JSmith
creation_date: 2013-12-20T12:53:06Z

[Term]
id: MMO:0000449
name: thymidine incorporation bioassay
def: "A method of determining the concentration, relative activity or effects of a biologically active substance in a sample based on the amount of radioactive thymidine, e.g., H3-thymidine, taken up by a culture of reporter cells (cells which depend for their viability and/or reproduction on the substance of interest) following application of the sample. The amount or activity of that substance in the sample is calculated by measuring the incorporation of radioactivity by the text cell culture following application of the sample compared with the incorporation of radioactivity following application of a reference standard." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, MESH:D001681, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, PMID:11817600]
synonym: "radioactive thymidine incorporation-based cell proliferation bioassay" RELATED []
is_a: MMO:0000442 ! cell proliferation bioassay
created_by: JSmith
creation_date: 2014-01-03T12:46:17Z

[Term]
id: MMO:0000450
name: ion-selective electrode method
def: "An electroanalytical technique which employs a sensor that converts the activity of a specific ion dissolved in a solution into an electrical potential and measures the resulting potential using a voltmeter or potentiometer." [http://en.wikipedia.org/wiki/Ion_selective_electrode "Wikipedia", Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "ISE method" RELATED []
synonym: "SIE method" RELATED []
synonym: "specific ion electrode method" EXACT []
is_a: MMO:0000386 ! electroanalytical method
created_by: JSmith
creation_date: 2014-01-03T17:33:50Z

[Term]
id: MMO:0000451
name: chloride ion-selective electrode method
def: "An electroanalytical technique which employs a sensor that converts the activity of a chloride ions (the chemical element with atomic number 17, that has gained one electron forming an anion with a charge of -1) in a solution into an electrical potential and measures the resulting potential using a voltmeter or potentiometer." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Ion_selective_electrode "Wikipedia", ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "chloride ISE method" RELATED []
synonym: "chloride SIE method" RELATED []
synonym: "chloride-specific ion electrode method" EXACT []
is_a: MMO:0000450 ! ion-selective electrode method
created_by: JSmith
creation_date: 2014-01-03T17:44:39Z

[Term]
id: MMO:0000452
name: sodium ion-selective electrode method
def: "An electroanalytical technique which employs a sensor that converts the activity of sodium ions (the chemical element with atomic number 11, that has lost one electron forming a cation with a charge of +1) in a solution into an electrical potential and measures the resulting potential using a voltmeter or potentiometer." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Ion_selective_electrode "Wikipedia", ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "sodium ISE method" RELATED []
synonym: "sodium SIE method" RELATED []
synonym: "sodium-specific ion electrode method" EXACT []
is_a: MMO:0000450 ! ion-selective electrode method
created_by: JSmith
creation_date: 2014-01-03T17:46:59Z

[Term]
id: MMO:0000453
name: potassium ion-selective electrode method
def: "An electroanalytical technique which employs a sensor that converts the activity of potassium ions (chemical element with atomic number 19, that has lost one electron forming a cation with a charge of +1) in a solution into an electrical potential and measures the resulting potential using a voltmeter or potentiometer." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Ion_selective_electrode "Wikipedia", ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "potassium ISE method" RELATED []
synonym: "potassium SIE method" RELATED []
synonym: "potassium-specific ion electrode method" EXACT []
is_a: MMO:0000450 ! ion-selective electrode method
created_by: JSmith
creation_date: 2014-01-03T17:47:03Z

[Term]
id: MMO:0000454
name: test apparatus method utilizing mechanical transducer
def: "A method utilizing a piece of physical instrumentation, machinery or equipment designed and used to measure the movements and/or behaviors of an organism, that makes use of a mechanical transducer to convert a physical/mechanical force or displacement signal to another, recordable, signal type." [http://en.wikipedia.org/wiki/Transducer "Wikipedia", Oxford:The_Online_Compact_Oxford_English_Dictionary]
is_a: MMO:0000255 ! movement/behavior test apparatus method
created_by: JSmith
creation_date: 2014-01-14T12:17:06Z

[Term]
id: MMO:0000455
name: test apparatus method utilizing piezoelectric accelerometer
def: "A method which utilizes a piece of physical instrumentation, machinery or equipment designed and used to measure the movements and/or behaviors of an organism in which a piezoelectric accelerometer converts mechanical force into an electrical signal that can be measured by the recording instrument. A piezoelectric accelerometer utilizes the piezoelectric effect of certain materials, that is, the accumulation of an electrical charge in a substance in response to applied mechanical stress, to measure dynamic changes in mechanical variables." [http://en.wikipedia.org/wiki/Piezoelectric_accelerometer "Wikipedia", http://www.new.mmf.de/introduction.htm "Website", Oxford:The_Online_Compact_Oxford_English_Dictionary]
is_a: MMO:0000454 ! test apparatus method utilizing mechanical transducer
created_by: JSmith
creation_date: 2014-01-14T12:18:56Z

[Term]
id: MMO:0000456
name: automated urine sodium analysis
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to assess the amount, proportions or properties of sodium in urine, the fluid waste product excreted by the kidneys. Sodium, the chemical element with atomic number 11 that in its ionic form has lost one electron, forming a cation with a charge of +1, is the chief cation of extracellular body fluids." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "automated urine Na+ analysis" RELATED []
synonym: "automated urine sodium ion analysis" EXACT []
is_a: MMO:0000177 ! automated urine analysis
is_a: MMO:0000434 ! urine sodium analysis
created_by: JSmith
creation_date: 2014-01-14T12:30:48Z

[Term]
id: MMO:0000457
name: urine pH analysis
def: "A test of the acidity or alkalinity of urine, expressed as the negative logarithm of the hydrogen ion concentration expressed in molarity." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000147 ! urine analysis
created_by: JSmith
creation_date: 2014-01-14T12:36:26Z

[Term]
id: MMO:0000458
name: enzyme-linked immunosorbent spot assay
def: "A modified version of the ELISA (enzyme-linked immunosorbent assay) protocol in which viable cells are plated onto membranes treated with antibodies against the molecule of interest. Analyte secreted from a cell is immediately adsorbed onto the membrane before dilution or difusion and membranes are processed as in the ELISA protocol, yielding spots represending individual activated or responding cells." [http://en.wikipedia.org/wiki/ELISPOT "Wikipedia"]
synonym: "ELISPOT assay" RELATED []
is_a: MMO:0000075 ! enzyme linked immunosorbent assay
created_by: JSmith
creation_date: 2014-01-14T12:55:54Z

[Term]
id: MMO:0000459
name: polymerase chain reaction assay
def: "A rapid technique for in vitro amplification of specific DNA sequences, allowing small quantities of short sequences to be analyzed without cloning. DNA sequences are amplified in vitro by separating the DNA into two strands and incubating it in a series of temperature cycles with oligonucleotide primers and heat-stable DNA polymerase." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "PCR" EXACT []
is_a: MMO:0000388 ! enzymatic method
is_a: MMO:0000641 ! transcript expression assay
created_by: JSmith
creation_date: 2014-01-14T13:21:30Z

[Term]
id: MMO:0000460
name: real-time polymerase chain reaction assay
def: "Real-time PCR is able to detect sequence-specific PCR products as they accumulate in 'real-time' during the PCR amplification process. As the PCR product of interest is produced, real-time PCR can detect their accumulation and quantify the number of substrates present in the initial PCR mixture before amplification began." [http://www.bio.davidson.edu/courses/genomics/method/realtimepcr.html]
synonym: "kinetic polymerase chain reaction" RELATED []
synonym: "qPCR" EXACT []
synonym: "quantitative real time polymerase chain reaction" EXACT []
synonym: "real-time PCR" EXACT []
is_a: MMO:0000459 ! polymerase chain reaction assay
created_by: JSmith
creation_date: 2014-01-14T13:23:47Z

[Term]
id: MMO:0000461
name: reverse transcription polymerase chain reaction
def: "A method which assesses transcript expression by conversion of an RNA template into complementary DNA (cDNA) by reverse transcription. The cDNA is used as a template for exponential amplification by the polymerase chain reaction, a technique which produces a large number of copies of one or more specific DNA sequences via multiple rounds of thermal cycling where DNA is melted, annealed to oligonucleotide primers, and extended using a thermostable DNA polymerase." [http://en.wikipedia.org/wiki/Polymerase_Chain_Reaction "Wikipedia"]
synonym: "RT-PCR" EXACT []
is_obsolete: true
created_by: JSmith
creation_date: 2014-01-14T13:23:50Z

[Term]
id: MMO:0000462
name: quantitative reverse transcription polymerase chain reaction
def: "Real-time PCR in which a sample of RNA is first reverse transcribed to convert the RNA into complementary DNA (cDNA) and then a quantitative real-time PCR reaction is carried out on the resulting sample." [http://en.wikipedia.org/wiki/Polymerase_Chain_Reaction "Wikipedia"]
synonym: "qRT-PCR" EXACT DISPLAY_SYNONYM []
synonym: "qRT-PCR" RELATED []
synonym: "quantitative RT-PCR" RELATED []
synonym: "real-time RT-PCR" RELATED []
is_obsolete: true
created_by: JSmith
creation_date: 2014-01-14T13:28:06Z

[Term]
id: MMO:0000463
name: urine potassium test strip
def: "A solid phase colorimetric assay utilizing a strip of paper, or of plastic with one or more attached pads of paper, impregnated with a reagent that specifically reacts with potassium ions. The strip is dipped into the urine sample, allowed to react for a specified period of time and the results assessed by a visual comparison with a standard chromatic/color scale or by an automated analyzer." [Collins:Collins_Online_English_Dictionary, http://en.wikipedia.org/wiki/Urine_test_strip "Wikipedia"]
synonym: "urine K+ test strip" RELATED []
is_a: MMO:0000171 ! urine test strip
is_a: MMO:0000435 ! urine potassium analysis
created_by: JSmith
creation_date: 2014-01-14T13:44:02Z

[Term]
id: MMO:0000464
name: urine sodium test strip
def: "A solid phase colorimetric assay utilizing a strip of paper, or of plastic with one or more attached pads of paper, impregnated with a reagent that specifically reacts with sodium ions. The strip is dipped into the urine sample, allowed to react for a specified period of time and the results assessed by a visual comparison with a standard chromatic/color scale or by an automated analyzer." [Collins:Collins_Online_English_Dictionary, http://en.wikipedia.org/wiki/Urine_test_strip "Wikipedia"]
synonym: "urine Na+ test strip" RELATED []
is_a: MMO:0000171 ! urine test strip
is_a: MMO:0000434 ! urine sodium analysis
created_by: JSmith
creation_date: 2014-01-14T13:51:35Z

[Term]
id: MMO:0000465
name: radiotelemetry electrocardiography
def: "A procedure for making graphic records of the variations in electrical potential caused by electrical activity of the heart muscle in which the sensor is located within the body and the measurement is based on data transmitted by radio waves from the subject to the recording apparatus." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed]
synonym: "radiotelemetry ECG" RELATED []
synonym: "radiotelemetry EKG" RELATED []
is_a: MMO:0000003 ! electrocardiography
created_by: JSmith
creation_date: 2014-01-14T14:11:50Z

[Term]
id: MMO:0000466
name: serum total phospholipid measurement test
def: "A laboratory test which measures all, i.e. the entirety, of the phospholipids, phosphorous-containing lipids composed mainly of fatty acids, a phosphate group, and a simple organic molecule, in serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Collins:Collins_Online_English_Dictionary, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "total serum phospholipid analysis" RELATED []
is_a: MMO:0000479 ! blood total phospholipid measurement test
created_by: JSmith
creation_date: 2014-01-14T16:02:57Z

[Term]
id: MMO:0000467
name: phospholipid analysis of serum lipoprotein fraction
def: "A laboratory test which measures the level of one or more phospholipids, phosphorous-containing lipids composed mainly of fatty acids, a phosphate group, and a simple organic molecule, in a lipoprotein fraction of serum. Serum lipoprotein fractions are samples resulting from the separation of the components of serum on the basis of density, such as by density gradient ultracentrifugation." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:8698878]
synonym: "serum lipoprotein fraction phospholipid analysis" RELATED []
synonym: "serum lipoprotein fraction phospholipid measurement test" RELATED []
is_obsolete: true
created_by: JSmith
creation_date: 2014-01-14T16:04:16Z

[Term]
id: MMO:0000468
name: column chromatography
def: "Any chromatographic technique, i.e. a technique for separating and/or analyzing a complex mixture based on its differential movement through a two-phase system, in which the mobile phase moves through a tube filled, lined or packed with the stationary phase." [http://chemwiki.ucdavis.edu/Analytical_Chemistry/Instrumental_Analysis/Chromatography/Chromatographic_Columns "Website"]
is_a: MMO:0000288 ! chromatography
created_by: JSmith
creation_date: 2014-01-14T17:41:52Z

[Term]
id: MMO:0000469
name: gas chromatography
def: "Any of a group of analytical separation techniques used to analyze volatile substances in the gas phase. In gas chromatography, the components of a sample are dissolved in a solvent and vaporized in order to separate the analytes by distributing the sample between two phases: a stationary phase and a mobile phase. The mobile phase is a chemically inert gas that serves to carry the molecules of the analyte through the heated column; the stationary phase can be either a solid adsorbant or a liquid on an inert support." [http://chemwiki.ucdavis.edu/Analytical_Chemistry/Instrumental_Analysis/Chromatography/Gas_Chromatography "Website"]
synonym: "gas column chromatography" EXACT []
synonym: "GC" RELATED []
synonym: "Not4Curation" RELATED []
synonym: "vapor-phase chromatography" RELATED []
synonym: "VPC" RELATED []
is_a: MMO:0000468 ! column chromatography
created_by: JSmith
creation_date: 2014-01-14T17:52:38Z

[Term]
id: MMO:0000470
name: gas-solid chromatography
def: "An analytical separation technique used to analyze volatile substances in the gas phase. The components of a sample are dissolved in a solvent and vaporized in order to separate the analytes by distributing the sample between two phases:  a mobile phase comprised of a chemically inert gas that serves to carry the molecules of the analyte through the heated column, and a stationary phase consisting of a solid adsorbant." [http://chemwiki.ucdavis.edu/Analytical_Chemistry/Instrumental_Analysis/Chromatography/Gas_Chromatography "Website"]
synonym: "gas-solid column chromatography" EXACT []
synonym: "GSC" RELATED []
is_a: MMO:0000469 ! gas chromatography
created_by: JSmith
creation_date: 2014-01-14T17:56:27Z

[Term]
id: MMO:0000471
name: gas-liquid chromatography
def: "An analytical separation technique used to analyze volatile substances in the gas phase. The components of a sample are dissolved in a solvent and vaporized in order to separate the analytes by distributing the sample between two phases:  a mobile phase comprised of a chemically inert gas that serves to carry the molecules of the analyte through the heated column, and a stationary phase consisting of a liquid on an inert support." [http://chemwiki.ucdavis.edu/Analytical_Chemistry/Instrumental_Analysis/Chromatography/Gas_Chromatography "Website"]
synonym: "gas-liquid column chromatography" EXACT []
synonym: "GLC" RELATED []
is_a: MMO:0000469 ! gas chromatography
created_by: JSmith
creation_date: 2014-01-14T17:56:30Z

[Term]
id: MMO:0000472
name: blood intermediate-density lipoprotein cholesterol measurement test
def: "A test which determines the amount of cholesterol carried in intermediate-density lipoprotein (IDL) particles in blood. IDL are relatively large lipoprotein particles (complexes that consist of a protein layer surrounding a core of lipids) formed by degredation of very low density lipoproteins (VLDL) particles and thus having a size intermediate between those of VLDL and low density lipoproteins." [http://en.wikipedia.org/wiki/Intermediate-density_lipoprotein "Wikipedia", Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed]
synonym: "blood IDL-cholesterol test" RELATED []
is_a: MMO:0000489 ! blood differential lipoprotein-cholesterol analysis
created_by: JSmith
creation_date: 2014-01-15T11:15:19Z

[Term]
id: MMO:0000473
name: serum intermediate-density lipoprotein cholesterol measurement test
def: "A test which determines the amount of cholesterol carried in intermediate-density lipoprotein (IDL) particles in a sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. IDL are relatively large lipoprotein particles (complexes that consist of a protein membrane surrounding a core of lipids) formed by degredation of very low density lipoproteins (VLDL) particles and thus having a size intermediate between those of VLDL and low density lipoproteins." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Intermediate-density_lipoprotein "Wikipedia", ISBN:978-1416049982]
synonym: "serum IDL-cholesterol test" RELATED []
is_a: MMO:0000472 ! blood intermediate-density lipoprotein cholesterol measurement test
created_by: JSmith
creation_date: 2014-01-15T11:16:42Z

[Term]
id: MMO:0000474
name: plasma intermediate-density lipoprotein cholesterol measurement test
def: "A test which determines the amount of cholesterol carried in intermediate-density lipoprotein (IDL) particles in a sample of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. IDL are relatively large lipoprotein particles (complexes that consist of a protein membrane surrounding a core of lipids) formed by degredation of very low density lipoproteins (VLDL) particles and thus having a size intermediate between those of VLDL and low density lipoproteins." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Intermediate-density_lipoprotein "Wikipedia", ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed]
synonym: "plasma IDL-cholesterol test" RELATED []
is_a: MMO:0000472 ! blood intermediate-density lipoprotein cholesterol measurement test
created_by: JSmith
creation_date: 2014-01-15T11:18:52Z

[Term]
id: MMO:0000475
name: blood high-density lipoprotein phospholipid measurement test
def: "A laboratory test which measures the amount of phospholipid (phosphorus-containing lipids composed mainly of fatty acids, a phosphate group, and a simple organic molecule) found in the high-density lipoprotein (HDL) fraction of blood. HDL is the smallest (diameter approximately 5-15 nm) of the major lipoprotein particles, complex particles that consist of a protein layer surrounding a core of lipids." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Lipoprotein "Wikipedia", ISBN:978-1416049982]
synonym: "blood HDL phospholipid test" EXACT []
is_a: MMO:0000490 ! blood differential lipoprotein-phospholipid analysis
created_by: JSmith
creation_date: 2014-01-15T11:29:50Z

[Term]
id: MMO:0000476
name: blood intermediate-density lipoprotein phospholipid measurement test
def: "A laboratory test which measures the amount of phospholipid (phosphorus-containing lipids composed mainly of fatty acids, a phosphate group, and a simple organic molecule) found in the intermediate-density lipoprotein (IDL) fraction of blood. IDL are relatively large lipoprotein particles (complexes that consist of a protein layer surrounding a core of lipids) formed by degredation of very low density lipoproteins (VLDL) particles and thus having a size intermediate between those of VLDL and low density lipoproteins (diameter approximately 25-50 nm)." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, http://en.wikipedia.org/wiki/Intermediate-density_lipoprotein "Wikipedia"]
synonym: "blood IDL phospholipid test" EXACT []
is_a: MMO:0000490 ! blood differential lipoprotein-phospholipid analysis
created_by: JSmith
creation_date: 2014-01-15T11:31:37Z

[Term]
id: MMO:0000477
name: blood low-density lipoprotein phospholipid measurement test
def: "A laboratory test which measures the amount of phospholipid (phosphorus-containing lipids composed mainly of fatty acids, a phosphate group, and a simple organic molecule) found in the low-density lipoprotein (LDL) fraction of blood. LDL consitute a class of relatively large (diameter approximately 18-28 nm), heterogeneous lipoprotein particles, complexes that consist of a protein layer surrounding a core of lipids." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Lipoprotein "Wikipedia", ISBN:978-1416049982]
synonym: "blood LDL phospholipid test" EXACT []
is_a: MMO:0000490 ! blood differential lipoprotein-phospholipid analysis
created_by: JSmith
creation_date: 2014-01-15T11:34:17Z

[Term]
id: MMO:0000478
name: blood very low-density lipoprotein phospholipid measurement test
def: "A laboratory test which measures the amount of phospholipid (phosphorus-containing lipids composed mainly of fatty acids, a phosphate group, and a simple organic molecule) found in the very-low-density lipoprotein (VLDL) fraction of blood. VLDL consitute a class of large (diameter approximately 30-80 nm) lipoprotein particles, complexes that consist of a protein layer surrounding a core of lipids." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Lipoprotein "Wikipedia", ISBN:978-1416049982]
synonym: "blood VLDL phospholipid test" EXACT []
is_a: MMO:0000490 ! blood differential lipoprotein-phospholipid analysis
created_by: JSmith
creation_date: 2014-01-15T11:50:05Z

[Term]
id: MMO:0000479
name: blood total phospholipid measurement test
def: "A laboratory test which measures all, i.e. the entirety, of the phospholipids, phosphorous-containing lipids composed mainly of fatty acids, a phosphate group, and a simple organic molecule, in blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them." [Collins:Collins_Online_English_Dictionary, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed]
is_a: MMO:0000323 ! blood phospholipid analysis
created_by: JSmith
creation_date: 2014-01-15T11:52:41Z

[Term]
id: MMO:0000480
name: plasma total phospholipid measurement test
def: "A laboratory test which measures all, i.e. the entirety, of the phospholipids, phosphorous-containing lipids composed mainly of fatty acids, a phosphate group, and a simple organic molecule, in plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Collins:Collins_Online_English_Dictionary, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed]
synonym: "plasma total phospholipid analysis" RELATED []
is_a: MMO:0000479 ! blood total phospholipid measurement test
created_by: JSmith
creation_date: 2014-01-15T12:02:51Z

[Term]
id: MMO:0000481
name: serum high-density lipoprotein phospholipid measurement test
def: "A laboratory test which measures the amount of phospholipid (phosphorus-containing lipids composed mainly of fatty acids, a phosphate group, and a simple organic molecule) found in the high-density lipoprotein (HDL) fraction of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. HDL is the smallest (diameter approximately 5-15 nm) of the major lipoprotein particles, complexes that consist of a protein layer surrounding a core of lipids." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Lipoprotein "Wikipedia", ISBN:978-1416049982]
synonym: "serum HDL phospholipid test" EXACT []
is_a: MMO:0000475 ! blood high-density lipoprotein phospholipid measurement test
created_by: JSmith
creation_date: 2014-01-15T13:05:30Z

[Term]
id: MMO:0000482
name: plasma high-density lipoprotein phospholipid measurement test
def: "A laboratory test which measures the amount of phospholipid (phosphorus-containing lipids composed mainly of fatty acids, a phosphate group, and a simple organic molecule) found in the high-density lipoprotein (HDL) fraction of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. HDL is the smallest (diameter approximately 5-15 nm) of the major lipoprotein particles, complexes that consist of a protein layer surrounding a core of lipids." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Lipoprotein "Wikipedia", ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed]
synonym: "plasma HDL phospholipid test" EXACT []
is_a: MMO:0000475 ! blood high-density lipoprotein phospholipid measurement test
created_by: JSmith
creation_date: 2014-01-15T13:06:45Z

[Term]
id: MMO:0000483
name: serum intermediate-density lipoprotein phospholipid measurement test
def: "A laboratory test which measures the amount of phospholipid (phosphorus-containing lipids composed mainly of fatty acids, a phosphate group, and a simple organic molecule) found in the intermediate-density lipoprotein (IDL) fraction of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. IDL are relatively large lipoprotein particles (complexes that consist of a protein layer surrounding a core of lipids) formed by degredation of very low density lipoproteins (VLDL) particles and thus having a size intermediate between those of VLDL and low density lipoproteins (diameter approximately 25-50 nm)." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Intermediate-density_lipoprotein "Wikipedia", ISBN:978-1416049982]
synonym: "serum IDL phospholipid test" EXACT []
is_a: MMO:0000476 ! blood intermediate-density lipoprotein phospholipid measurement test
created_by: JSmith
creation_date: 2014-01-15T13:07:54Z

[Term]
id: MMO:0000484
name: plasma intermediate-density lipoprotein phospholipid measurement test
def: "A laboratory test which measures the amount of phospholipid (phosphorus-containing lipids composed mainly of fatty acids, a phosphate group, and a simple organic molecule) found in the intermediate-density lipoprotein (IDL) fraction of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. IDL are relatively large lipoprotein particles (complexes that consist of a protein layer surrounding a core of lipids) formed by degredation of very low density lipoproteins (VLDL) particles and thus having a size intermediate between those of VLDL and low density lipoproteins (diameter approximately 25-50 nm)." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Intermediate-density_lipoprotein "Wikipedia", ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed]
synonym: "plasma IDL phospholipid test" EXACT []
is_a: MMO:0000476 ! blood intermediate-density lipoprotein phospholipid measurement test
created_by: JSmith
creation_date: 2014-01-15T13:08:58Z

[Term]
id: MMO:0000485
name: serum low-density lipoprotein phospholipid measurement test
def: "A laboratory test which measures the amount of phospholipid (phosphorus-containing lipids composed mainly of fatty acids, a phosphate group, and a simple organic molecule) found in the low-density lipoprotein (LDL) fraction of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. LDL consitute a class of relatively large (diameter approximately 18-28 nm), heterogeneous lipoprotein particles, complexes that consist of a protein layer surrounding a core of lipids." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Lipoprotein "Wikipedia", ISBN:978-1416049982]
synonym: "serum LDL phospholipid test" EXACT []
is_a: MMO:0000477 ! blood low-density lipoprotein phospholipid measurement test
created_by: JSmith
creation_date: 2014-01-15T13:11:34Z

[Term]
id: MMO:0000486
name: plasma low-density lipoprotein phospholipid measurement test
def: "A laboratory test which measures the amount of phospholipid (phosphorus-containing lipids composed mainly of fatty acids, a phosphate group, and a simple organic molecule) found in the low-density lipoprotein (LDL) fraction of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. LDL consitute a class of relatively large (diameter approximately 18-28 nm), heterogeneous lipoprotein particles, complexes that consist of a protein layer surrounding a core of lipids." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Lipoprotein "Wikipedia", ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed]
synonym: "plasma LDL phospholipid test" EXACT []
is_a: MMO:0000477 ! blood low-density lipoprotein phospholipid measurement test
created_by: JSmith
creation_date: 2014-01-15T13:12:30Z

[Term]
id: MMO:0000487
name: serum very low-density lipoprotein phospholipid measurement test
def: "A laboratory test which measures the amount of phospholipid (phosphorus-containing lipids composed mainly of fatty acids, a phosphate group, and a simple organic molecule) found in the very-low-density lipoprotein (VLDL) fraction of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. VLDL consitute a class of large (diameter approximately 30-80 nm) lipoprotein particles, complexes that consist of a protein layer surrounding a core of lipids." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Lipoprotein "Wikipedia", ISBN:978-1416049982]
synonym: "serum VLDL phospholipid test" EXACT []
is_a: MMO:0000478 ! blood very low-density lipoprotein phospholipid measurement test
created_by: JSmith
creation_date: 2014-01-15T13:13:55Z

[Term]
id: MMO:0000488
name: plasma very low-density lipoprotein phospholipid measurement test
def: "A laboratory test which measures the amount of phospholipid (phosphorus-containing lipids composed mainly of fatty acids, a phosphate group, and a simple organic molecule) found in the very-low-density lipoprotein (VLDL) fraction of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. VLDL consitute a class of large (diameter approximately 30-80 nm) lipoprotein particles, complexes that consist of a protein layer surrounding a core of lipids." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Lipoprotein "Wikipedia", ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed]
synonym: "plasma VLDL phospholipid test" EXACT []
is_a: MMO:0000478 ! blood very low-density lipoprotein phospholipid measurement test
created_by: JSmith
creation_date: 2014-01-15T13:14:46Z

[Term]
id: MMO:0000489
name: blood differential lipoprotein-cholesterol analysis
def: "Any laboratory test which measures the amount of cholesterol carried by or specifically associated with a particular type of  lipoprotein (a complex particle that consists of a protein layer surrounding a core of lipids) in blood. Cholesterol is a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000167 ! blood lipoprotein analysis
is_a: MMO:0000491 ! blood cholesterol analysis
created_by: JSmith
creation_date: 2014-01-16T12:40:18Z

[Term]
id: MMO:0000490
name: blood differential lipoprotein-phospholipid analysis
def: "Any laboratory test which measures the amount of phospholipid (phosphorus-containing lipids composed mainly of fatty acids, a phosphate group, and a simple organic molecule) specifically associated with a particular type of lipoprotein, a complex that consists of a protein layer surrounding a core of lipids, in blood." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Lipoprotein "Wikipedia", ISBN:978-1416049982]
is_a: MMO:0000167 ! blood lipoprotein analysis
is_a: MMO:0000323 ! blood phospholipid analysis
created_by: JSmith
creation_date: 2014-01-16T12:51:29Z

[Term]
id: MMO:0000491
name: blood cholesterol analysis
def: "Any laboratory test which measures one or more properties such as the amount, composition, etc of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, in blood." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000518 ! blood sterol analysis
created_by: JSmith
creation_date: 2014-01-16T12:59:46Z

[Term]
id: MMO:0000492
name: in vivo linear measurement method
def: "Any procedure or technique performed in or on a living body, for example, a procedure performed on an organ in situ or on the entire living organism, by which a measurement is made in a straight line that connects two points directly." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, Farlex:Farlex_Partner_Medical_Dictionary_2012, ISBN:978-1416049982]
is_a: MMO:0000026 ! in vivo method
created_by: JSmith
creation_date: 2014-01-23T13:56:01Z

[Term]
id: MMO:0000493
name: measuring stick-based body length measuring method
def: "A procedure to measure the full length of the intact body of an organism, that is, the extent of the body along its greatest dimension, which employs a measuring stick, a measuring instrument having a sequence of marks at regular intervals; used as a reference in making measurements of length." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, http://www.vocabulary.com/dictionary/measuring_stick#word=measuring%20stick "Website"]
is_a: MMO:0000209 ! body length measuring method
is_a: MMO:0000210 ! in vivo measuring stick method
created_by: JSmith
creation_date: 2014-01-23T14:10:07Z

[Term]
id: MMO:0000494
name: ruler-based body length measuring method
def: "A procedure to measure the full length of the intact body of an organism, that is, the extent of the body along its greatest dimension, which employs a ruler, a strip of wood, metal, or other material, having straight edges and graduated, for example in millimetres or inches, used for measuring lengths." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, Collins:Collins_Online_English_Dictionary]
is_a: MMO:0000209 ! body length measuring method
is_a: MMO:0000211 ! in vivo ruler method
created_by: JSmith
creation_date: 2014-01-23T14:17:45Z

[Term]
id: MMO:0000495
name: ex vivo linear measurement method
def: "A procedure or technique performed outside (i.e., distinct from or removed from) the living body by which a measurement is made in a straight line that connects two points directly." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, Farlex:Farlex_Partner_Medical_Dictionary_2012, ISBN:978-1416049982]
is_a: MMO:0000027 ! ex vivo method
created_by: JSmith
creation_date: 2014-01-23T14:27:27Z

[Term]
id: MMO:0000496
name: histology
def: "The anatomical study of the microscopic structure of animal and plant tissues." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed]
is_a: MMO:0000109 ! ex vivo microscopy
created_by: JSmith
creation_date: 2014-01-23T14:37:26Z

[Term]
id: MMO:0000497
name: histochemistry
def: "The branch of histology dealing with the identification of chemical components in cells and tissues, especially the microscopic analysis of chemical components and/or structures in cells and tissues by staining, directly or indirectly, with fluorescent or pigmented materials." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, RGD:GTH]
is_a: MMO:0000496 ! histology
created_by: JSmith
creation_date: 2014-01-23T14:38:04Z

[Term]
id: MMO:0000498
name: immunohistochemistry
def: "Microscopic analysis of structure and/or localization of specific antigens in cells and tissues by staining with antibodies labeled with fluorescent or pigmented material." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007]
synonym: "IHC" RELATED []
synonym: "immunohistochemistry" EXACT DISPLAY_SYNONYM []
xref: ECO:0001055
xref: OBI:0001986
is_a: MMO:0000497 ! histochemistry
is_a: MMO:0000642 ! protein expression assay
is_a: MMO:0000643 ! in situ expression assay
created_by: JSmith
creation_date: 2014-01-23T14:40:13Z

[Term]
id: MMO:0000499
name: ex vivo microscopic linear measurement method
def: "A procedure or technique performed outside (i.e., distinct from or removed from) the living body by which a measurement is made in a straight line that connects two points directly on a microscopic scale, that is, using an instrument to obtain an enlarged image of small objects and reveal details of structure not otherwise distinguishable." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, Farlex:Farlex_Partner_Medical_Dictionary_2012, ISBN:978-1416049982]
is_a: MMO:0000109 ! ex vivo microscopy
is_a: MMO:0000495 ! ex vivo linear measurement method
created_by: JSmith
creation_date: 2014-01-23T14:54:05Z

[Term]
id: MMO:0000500
name: ex vivo linear measurement method using electron microscopy
def: "A procedure or technique performed outside (i.e., distinct from or removed from) the living body by which a measurement is made in a straight line that directly connects two points using an electron microscopea microscope using beams of electrons, negatively charged elementary particles, to produce highly magnified images." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, Farlex:Farlex_Partner_Medical_Dictionary_2012, ISBN:978-1416049982]
is_a: MMO:0000110 ! ex vivo electron microscopy
is_a: MMO:0000499 ! ex vivo microscopic linear measurement method
created_by: JSmith
creation_date: 2014-01-23T15:07:12Z

[Term]
id: MMO:0000501
name: ex vivo linear measurement method using light microscopy
def: "A procedure or technique performed outside (i.e., distinct from or removed from) the living body by which a measurement is made in a straight line that directly connects two points using a light microscope, an optical instrument that uses visible light processed through a lens or a combination of lenses to produce magnified images." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, Farlex:Farlex_Partner_Medical_Dictionary_2012, ISBN:978-1416049982]
is_a: MMO:0000111 ! ex vivo light microscopy
is_a: MMO:0000499 ! ex vivo microscopic linear measurement method
created_by: JSmith
creation_date: 2014-01-23T14:59:59Z

[Term]
id: MMO:0000502
name: cell-based bioassay
def: "Any method to determine the strength or biological activity of a drug, hormone or other substance by comparing its effects on isolated cells with those of a reference standard, or to experimentally investigate the properties or functions of isolated cells." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, RGD:JRS]
is_a: MMO:0000441 ! bioassay
created_by: JSmith
creation_date: 2014-01-23T15:31:33Z

[Term]
id: MMO:0000503
name: cell proliferation assay
def: "An experimental procedure to measure the rate, level or amount of growth and reproduction of isolated cells." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007]
comment: Scope note:  this term is intended for use in cases where the resulting measurement is of the growth of the cells, not when cell growth is used as a readout to determine the amount or activity of an applied substance. For that application, use "cell proliferation bioassay" (MMO:0000442).
is_a: MMO:0000222 ! isolated cell method
created_by: JSmith
creation_date: 2014-01-23T15:34:08Z

[Term]
id: MMO:0000504
name: urine protein sulfosalicylic acid precipitation test
def: "A method in which sulfosalicylic acid (that is, the SSA reagent) is added to a small and equal volume of clear urine. The acidification causes precipitation of protein in the sample (seen as increasing turbidity), which can be subjectively quantitated visually or more precisely quantitated using photometry." [http://www.austincc.edu/mlt/ua/UrineProteinSulfosalicylicAcidPrecipitationTest.pdf "Website", http://www.fpnotebook.com/Urology/Lab/SlfslcylcAcd.htm "Website"]
synonym: "SSA protein precipitation test" RELATED []
synonym: "urine SSA turbidimetry" RELATED []
synonym: "urine sulfosalicylic acid turbidimetry" RELATED []
synonym: "urine turbidimetry with sulfosalicylic acid" RELATED []
is_a: MMO:0000335 ! urine total protein analysis
created_by: JSmith
creation_date: 2014-02-07T11:53:04Z

[Term]
id: MMO:0000505
name: glove test
def: "An experimental method in which an animal (for example, a rat) is placed in an experimental apparatus or test cage and subsequently presented with a gloved human hand, passively and/or with attempts to handle the animal, and reactions are assessed." [PMID:18177873]
is_a: MMO:0000586 ! wildness/tameness assessment method
created_by: JSmith
creation_date: 2014-02-07T12:50:09Z

[Term]
id: MMO:0000506
name: glove test with visual analysis of video recording
def: "An experimental method in which an animal (for example, a rat) is placed in an experimental apparatus or test cage and subsequently presented with a gloved human hand, passively and/or with attempts to handle the animal and the animal's reactions are recorded. These reactions are then evaluated, appraised or perceived through the sense of sight by watching the stored sound- and image-based record of the organism." [PMID:18177873]
is_a: MMO:0000401 ! visual assessment of in vivo video recording
is_a: MMO:0000505 ! glove test
created_by: JSmith
creation_date: 2014-02-07T12:50:52Z

[Term]
id: MMO:0000507
name: wire electrode telemetric electrocardiography with power spectral analysis
def: "A procedure in which graphic records of the variations in electrical potential caused by electrical activity of the heart muscle are made utilizing a sensor located within the body with the measurement based on data transmitted by radio waves from the subject to the recording apparatus. Subsequently, these measurements are subjected to a computer analysis of variances in heart function." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:2874900, Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed]
synonym: "radiotelemetry ECG" RELATED []
synonym: "radiotelemetry EKG" RELATED []
is_a: MMO:0000465 ! radiotelemetry electrocardiography
created_by: JSmith
creation_date: 2014-02-07T13:02:23Z

[Term]
id: MMO:0000508
name: in vivo whole body quantitative computed tomography
def: "A computed tomography (CT) technique that uses a low radiation dose to analyze (for example to determine size or composition) and/or visualize the internal organs and tissues across the entire body of a living organism." [http://en.wikipedia.org/wiki/Quantitative_computed_tomography "Wikipedia", http://www.hitachi-aloka.co.jp/english/products/animal/lct200/index.html "Website", http://www.thefreedictionary.com/ "Multiple_Dictionaries"]
comment: Peripheral quantitative computed tomography can be performed on excised bones as well as bones in vivo. This term, being in the "in vivo method" branch of the MMO, does not cover ex vivo usage of the technique. For that application please use the term "ex vivo peripheral quantitative computed tomography", MMO:0000367.
synonym: "in vivo whole body quantitative CT" RELATED []
is_a: MMO:0000364 ! quantitative computed tomography
created_by: JSmith
creation_date: 2014-03-05T14:55:33Z

[Term]
id: MMO:0000509
name: audiometry
def: "Any method by which the acuity of hearing for the various frequencies of sound waves is measured." [Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed]
is_a: MMO:0000026 ! in vivo method
created_by: JSmith
creation_date: 2014-03-07T14:35:53Z

[Term]
id: MMO:0000510
name: evoked response audiometry
def: "A method of testing hearing ability at the level of the brainstem and/or auditory cortex." [Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "ABR audiometry" RELATED []
synonym: "auditory brainstem response audiometry" RELATED []
is_a: MMO:0000509 ! audiometry
created_by: JSmith
creation_date: 2014-03-07T14:44:33Z

[Term]
id: MMO:0000511
name: metabolic cage urine volume measurement method
def: "A method which utilizes a metabolic cage, a housing unit constructed for the separate collection of liquid and solid wastes and in some cases for measurement of liquid waste, to determine the size of the three dimensional space occupied by a sample of urine, the fluid waste product excreted by the kidneys." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, American_Heritage:The_American_Heritage_Science_Dictionary_2005, http://www.pharmacelsus.de/metabolic_cage/ "Website"]
is_a: MMO:0000357 ! urine volume measurement method
created_by: JSmith
creation_date: 2014-03-10T11:20:37Z

[Term]
id: MMO:0000512
name: lipid peroxide analysis by liquid phase colorimetry
def: "Method of assessing the amount one or more end products of lipid peroxidation, the oxidative degradation of lipids, in a solution using a technique in which the color of that solution, usually after a chemical or enzymatic reaction, is compared to a color standard." [PMID:36810]
is_a: MMO:0000329 ! liquid phase colorimetry
created_by: JSmith
creation_date: 2014-03-11T17:13:57Z

[Term]
id: MMO:0000513
name: thiobarbituric acid assay
def: "Method of assessing the amount one or more end products of lipid peroxidation, the oxidative degradation of lipids, in a solution using an assay in which thiobarbituric acid is heated with a tissue or biological fluid sample at an acidic pH to produce a red chromogen. The level of TBA-reactive substances in the sample is determined by spectrophotometric analysis of absorbtion at ~532 nm or fluorescence at 553 nm." [PMID:36810]
synonym: "lipid peroxide analysis using the thiobarbituric acid assay with spectrophotometric readout" RELATED []
synonym: "TBA assay" RELATED []
synonym: "TBARS assay" RELATED []
synonym: "TBA test" RELATED []
is_a: MMO:0000512 ! lipid peroxide analysis by liquid phase colorimetry
created_by: JSmith
creation_date: 2014-03-11T17:18:02Z

[Term]
id: MMO:0000514
name: ex vivo caliper method
def: "A procedure or technique performed outside the living body, for example, a procedure performed on an organ or tissue after removal from the body, to measure the thickness or diameter of a solid using a compass with bent or curved legs or a device comprised of a calibrated scale with a fixed jaw, and another jaw, with a pointer, that slides along the scale from which the distance between the two pieces can be read." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Calipers "Wikipedia", ISBN:978-1416049982]
is_a: MMO:0000495 ! ex vivo linear measurement method
created_by: JSmith
creation_date: 2014-04-24T15:51:24Z

[Term]
id: MMO:0000515
name: ex vivo slide caliper method
def: "A method which makes use of a slide caliper, an instrument consisting of a calibrated scale with a fixed jaw, and a second (movable) jaw, with a pointer, that slides along the scale from which the distance between the two pieces can be read. The readout of a slide caliper can be a simple scale, a vernier scale, a dial or a digital display." [http://en.wikipedia.org/wiki/Calipers "Wikipedia"]
is_a: MMO:0000514 ! ex vivo caliper method
created_by: JSmith
creation_date: 2014-04-24T16:17:36Z

[Term]
id: MMO:0000516
name: ex vivo digital caliper method
def: "A method which uses a slide caliper with an electronic digital display on which the measurement is displayed as a single value with a set accuracy and resolution." [http://en.wikipedia.org/wiki/Calipers "Wikipedia"]
is_a: MMO:0000515 ! ex vivo slide caliper method
created_by: JSmith
creation_date: 2014-04-24T16:18:29Z

[Term]
id: MMO:0000517
name: ex vivo dial caliper method
def: "A method which uses a slide caliper with dial and arrow that points to the reading to display the finer, more precise portion of the measurement." [http://en.wikipedia.org/wiki/Calipers "Wikipedia"]
is_a: MMO:0000515 ! ex vivo slide caliper method
created_by: JSmith
creation_date: 2014-04-24T16:18:32Z

[Term]
id: MMO:0000518
name: blood sterol analysis
def: "Any method to determine the nature, properties, or composition of sterols in extracted blood. Sterols are any of a group of steroids with a long (8 to 10 carbons) aliphatic side-chain at position 17 and at least one alcoholic group." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "blood sterol measurement test" RELATED []
xref: CHEBI:15889
is_a: MMO:0000038 ! blood lipid analysis
created_by: JSmith
creation_date: 2014-04-29T14:44:51Z

[Term]
id: MMO:0000519
name: blood phytosterol analysis
def: "Any method to determine the nature, properties, or composition of phytosterol(s) in extracted blood. Phytosterols, which encompass both plant sterols and stanols, comprise a large group of steroid compounds similar to cholesterol that occur in plants and vary only in carbon side chains and/or presence or absence of a double bond." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "blood phytosterol measurement test" RELATED []
xref: CHEBI:26125
is_a: MMO:0000518 ! blood sterol analysis
created_by: JSmith
creation_date: 2014-04-29T14:46:20Z

[Term]
id: MMO:0000520
name: blood campesterol measurement test
def: "A method to determine the nature, properties, or composition of campesterol in extracted blood. Campesterol is a phytosterol (molecular formula C28H48O) whose chemical structure is similar to that of cholesterol." [http://en.wikipedia.org/wiki/Campesterol "Wikipedia", Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "blood campesterol analysis" RELATED []
xref: CHEBI:28623
is_a: MMO:0000519 ! blood phytosterol analysis
created_by: JSmith
creation_date: 2014-04-29T14:47:56Z

[Term]
id: MMO:0000521
name: blood sitosterol measurement test
def: "A method to determine the nature, properties, or composition of sitosterol in extracted blood. Sitosterol is a phytosterol (molecular formula C29H50O) with chemical structures similar to that of cholesterol." [http://en.wikipedia.org/wiki/Sitosterol "Wikipedia", Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "blood sitosterol analysis" RELATED []
xref: CHEBI:27693
is_a: MMO:0000519 ! blood phytosterol analysis
created_by: JSmith
creation_date: 2014-04-29T14:48:03Z

[Term]
id: MMO:0000522
name: serum sitosterol measurement test
def: "A method to determine the nature, properties, or composition of sitosterol in serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. Sitosterol is a phytosterol (molecular formula C29H50O) with chemical structures similar to that of cholesterol." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Sitosterol "Wikipedia", ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "serum sitosterol analysis" RELATED []
xref: CHEBI:27693
is_a: MMO:0000521 ! blood sitosterol measurement test
created_by: JSmith
creation_date: 2014-04-29T14:51:28Z

[Term]
id: MMO:0000523
name: plasma sitosterol measurement test
def: "A method to determine the nature, properties, or composition of sitosterol in plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. Sitosterol is a phytosterol (molecular formula C29H50O) with chemical structures similar to that of cholesterol." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Sitosterol "Wikipedia", ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "plasma sitosterol analysis" RELATED []
xref: CHEBI:27693
is_a: MMO:0000521 ! blood sitosterol measurement test
created_by: JSmith
creation_date: 2014-04-29T14:51:32Z

[Term]
id: MMO:0000524
name: plasma campesterol measurement test
def: "A method to determine the nature, properties, or composition of campesterol in plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. Campesterol is a phytosterol (molecular formula C28H48O) whose chemical structure is similar to that of cholesterol." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Campesterol "Wikipedia", ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "plasma campesterol analysis" RELATED []
xref: CHEBI:28623
is_a: MMO:0000520 ! blood campesterol measurement test
created_by: JSmith
creation_date: 2014-04-29T14:55:44Z

[Term]
id: MMO:0000525
name: serum campesterol measurement test
def: "A method to determine the nature, properties, or composition of campesterol in serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. Campesterol is a phytosterol (molecular formula C28H48O) whose chemical structure is similar to that of cholesterol." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Campesterol "Wikipedia", ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "serum campesterol analysis" RELATED []
xref: CHEBI:28623
is_a: MMO:0000520 ! blood campesterol measurement test
created_by: JSmith
creation_date: 2014-04-29T14:55:47Z

[Term]
id: MMO:0000526
name: isolated tissue lipid analysis
def: "Any method to determine the nature, properties, or composition of lipids in a specified sample of tissue after removal of that tissue from the body. Lipids are a heterogeneous group of fats and fatlike substances, including fatty acids, neutral fats, waxes, and steroids, which are insoluble in water but soluble in nonpolar solvents. Among other biological functions, lipids serve as a source of fuel and are an important constituent of cell structure." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "isolated tissue lipid measurement method" RELATED []
xref: CHEBI:18059
is_a: MMO:0000161 ! isolated tissue method
created_by: JSmith
creation_date: 2014-04-29T15:57:24Z

[Term]
id: MMO:0000527
name: isolated tissue triglyceride measurement test
def: "A method to determine the nature, properties, or composition of triglyceride in a specified sample of tissue after removal of that tissue from the body. Triglyceride is a compound consisting of three molecules of fatty acid esterified to glycerol. Triglyceride is a neutral fat that constitutes the usual storage form of lipids in animals." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "isolated tissue triglyceride analysis" RELATED []
xref: CHEBI:17855
is_a: MMO:0000526 ! isolated tissue lipid analysis
created_by: JSmith
creation_date: 2014-04-29T15:59:49Z

[Term]
id: MMO:0000528
name: isolated tissue sterol analysis
def: "Any method to determine the nature, properties, or composition of sterols in a specified sample of tissue after removal of that tissue from the body. Sterols are any of a group of steroids with a long (8 to 10 carbons) aliphatic side-chain at position 17 and at least one alcoholic group." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "isolated tissue sterol measurement method" RELATED []
xref: CHEBI:15889
is_a: MMO:0000526 ! isolated tissue lipid analysis
created_by: JSmith
creation_date: 2014-04-29T16:01:30Z

[Term]
id: MMO:0000529
name: isolated tissue cholesterol measurement test
def: "A method to determine the nature, properties, or composition of cholesterol in a specified sample of tissue after removal of that tissue from the body. Cholesterol is a eukaryotic sterol that, in higher animals, is the precursor of bile acids and steroid hormones and a key constituent of cell membranes." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "isolated tissue cholesterol analysis" RELATED []
synonym: "isolated tissue cholesterol measurement method" RELATED []
xref: CHEBI:16113
is_a: MMO:0000528 ! isolated tissue sterol analysis
created_by: JSmith
creation_date: 2014-04-29T16:04:31Z

[Term]
id: MMO:0000530
name: isolated tissue phytosterol analysis
def: "Any method to determine the nature, properties, or composition of phytosterol(s) in a specified sample of tissue after removal of that tissue from the body. Phytosterols, which encompass both plant sterols and stanols, comprise a large group of steroid compounds similar to cholesterol that occur in plants and vary only in carbon side chains and/or presence or absence of a double bond." [http://en.wikipedia.org/wiki/Phytosterol "Wikipedia", Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "isolated tissue phytosterol measurement method" RELATED []
xref: CHEBI:26125
is_a: MMO:0000528 ! isolated tissue sterol analysis
created_by: JSmith
creation_date: 2014-04-29T16:06:04Z

[Term]
id: MMO:0000531
name: isolated tissue campesterol measurement test
def: "A method to determine the nature, properties, or composition of campesterol in a specified sample of tissue after removal of that tissue from the body. Campesterol is a phytosterol (molecular formula C28H48O) whose chemical structure is similar to that of cholesterol." [http://en.wikipedia.org/wiki/Campesterol "Wikipedia", Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "isolated tissue campesterol analysis" RELATED []
synonym: "isolated tissue campesterol measurement method" RELATED []
xref: CHEBI:28623
is_a: MMO:0000530 ! isolated tissue phytosterol analysis
created_by: JSmith
creation_date: 2014-04-29T16:07:43Z

[Term]
id: MMO:0000532
name: isolated tissue sitosterol measurement test
def: "A method to determine the nature, properties, or composition of sitosterol in a specified sample of tissue after removal of that tissue from the body. Sitosterol is a phytosterol (molecular formula C29H50O) with chemical structures similar to that of cholesterol." [http://en.wikipedia.org/wiki/Sitosterol "Wikipedia", Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "isolated tissue sitosterol analysis" RELATED []
synonym: "isolated tissue sitosterol measurement method" RELATED []
xref: CHEBI:27693
is_a: MMO:0000530 ! isolated tissue phytosterol analysis
created_by: JSmith
creation_date: 2014-04-29T16:07:47Z

[Term]
id: MMO:0000533
name: white blood cell counting method
def: "Any method, manual or automated, by which the number, specifically of white blood cells (leukocytes), in a sample of blood is assessed and a value assigned. Leukocytes are largely colorless blood corpuscles capable of ameboid movement, whose chief function is to protect the body against microorganisms and other disease-causing entities." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "blood leukocyte counting method" EXACT []
is_a: MMO:0000445 ! blood cell counting method
created_by: JSmith
creation_date: 2014-04-29T16:49:07Z

[Term]
id: MMO:0000534
name: mass spectrometry
def: "A method for identifying molecules based on the detection of the mass-to-charge ratio of ions generated from the molecule by vaporisation and electron bombardment. Deflection of the ions through a magnetic field results in a characteristic pattern which is used to define the molecule of interest." [Segen:Segens_Medical_Dictionary_2012]
synonym: "mass spec" EXACT DISPLAY_SYNONYM []
xref: OBI:0000470
is_a: MMO:0000172 ! spectrometry
is_a: MMO:0000642 ! protein expression assay
created_by: JSmith
creation_date: 2014-06-05T14:49:06Z

[Term]
id: MMO:0000535
name: liquid chromatography-mass spectrometry
def: "An analytical technique in that combines the physical separation capabilities of liquid chromatography (LC) with the mass analysis capabilities of mass spectrometry (MS). Molecular mixtures are initially separated into components based on their chemicophysical properties and the properties of the liquid and stationary phases of the column. As these components exit the column, they are subjected to mass spectrometry for identification based on their mass-to-charge ratio and behavior in a magnetic field." [http://orgchem.colorado.edu/Technique/Procedures/Columnchrom/Columnchrom.html "Website", Segen:Segens_Medical_Dictionary_2012]
synonym: "LC-MS" RELATED []
is_a: MMO:0000404 ! liquid column chromatography
is_a: MMO:0000534 ! mass spectrometry
created_by: JSmith
creation_date: 2014-06-05T14:59:03Z

[Term]
id: MMO:0000536
name: gas chromatography-mass spectrometry
def: "An analytical technique in that combines the physical separation capabilities of gas chromatography (GC) with the mass analysis capabilities of mass spectrometry (MS). Molecular mixtures are initially vaporized and separated into components by GC. As these components exit the column, they are subjected to mass spectrometry for identification based on their mass-to-charge ratio and behavior in a magnetic field." [http://chemwiki.ucdavis.edu/Analytical_Chemistry/Instrumental_Analysis/Chromatography/Gas_Chromatography "Website", Segen:Segens_Medical_Dictionary_2012]
synonym: "GC-MS" RELATED []
is_a: MMO:0000469 ! gas chromatography
is_a: MMO:0000534 ! mass spectrometry
created_by: JSmith
creation_date: 2014-06-05T15:09:23Z

[Term]
id: MMO:0000537
name: high-performance liquid chromatography-mass spectrometry
def: "An analytical technique in that combines the physical separation capabilities of high pressure liquid chromatography (HPLC) with the mass analysis capabilities of mass spectrometry (MS). Molecular mixtures are initially separated into components by HPLC. As these components exit the column, they are subjected to mass spectrometry for identification based on their mass-to-charge ratio and behavior in a magnetic field." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Segen:Segens_Medical_Dictionary_2012]
synonym: "high pressure liquid chromatography-mass spectrometry" RELATED []
synonym: "HPLC-MS" RELATED []
is_a: MMO:0000394 ! high-performance liquid chromatography
is_a: MMO:0000534 ! mass spectrometry
created_by: JSmith
creation_date: 2014-06-05T15:09:27Z

[Term]
id: MMO:0000538
name: ex vivo light microscopy with immunohistochemistry
def: "A method performed outside the living body, for instance, on isolated tissue, which incorporates use of light microscopy and immunohistochemistry to produce magnified images. Immunohistochemistry is the microscopic localization of specific antigens in tissues by staining with antibodies labeled with fluorescent or pigmented material." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed, American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
is_a: MMO:0000111 ! ex vivo light microscopy
is_a: MMO:0000498 ! immunohistochemistry
created_by: JSmith
creation_date: 2014-06-05T16:28:40Z

[Term]
id: MMO:0000539
name: automated bromocresol green-based plasma albumin analysis with spectrophotometric readout
def: "An automated method in which bromocresol green and plasma proteins, especially albumin, are bound at acidic pH (approximately pH 4.1 - 4.3) to produce a blue to blue-green albumin-BCG complex. The intensity of the blue color of the resulting solution, measured as part of the automated process by a spectrophotometer at 620 - 630 nm, is directly proportional to the amount of albumin in the sample." [http://webmedia.unmc.edu/alliedhealth/CLS/CLS414%2009/Albumin%2009.pdf "Website"]
is_a: MMO:0000331 ! protein analysis by liquid phase colorimetry with spectrophotometric readout
is_a: MMO:0000351 ! automated plasma albumin analysis
created_by: JSmith
creation_date: 2014-06-10T11:59:38Z

[Term]
id: MMO:0000540
name: creatinine analysis by liquid phase colorimetry
def: "Method of assessing the amount of creatinine, the metabolized by-product of creatine, in a solution using a technique in which the color of that solution, usually after a chemical or enzymatic reaction, is compared to the color(s) of one or more standard solutions of creatinine." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Gale:Gale_Encyclopedia_of_Medicine_2008]
synonym: "liquid phase colorimetric creatinine analysis" EXACT []
is_a: MMO:0000329 ! liquid phase colorimetry
created_by: JSmith
creation_date: 2014-06-10T13:35:30Z

[Term]
id: MMO:0000541
name: creatinine analysis by liquid phase colorimetry with spectrophotometric readout
def: "Method of assessing the amount of creatinine, the metabolized by-product of creatine, in a solution using a technique in which the color of that solution, usually after a chemical or enzymatic reaction, is compared to the one or more standard solutions of creatinine using a spectrophotometer to assess the color and/or level of transmitted light for each solution." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Gale:Gale_Encyclopedia_of_Medicine_2008, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "liquid phase colorimetric creatinine analysis with spectrophotometric readout" EXACT []
is_a: MMO:0000173 ! spectrophotometry
is_a: MMO:0000540 ! creatinine analysis by liquid phase colorimetry
created_by: JSmith
creation_date: 2014-06-10T13:38:03Z

[Term]
id: MMO:0000542
name: creatinine analysis by Jaffe reaction with spectrophotometric readout
def: "A method for assaying creatinine in a sample using the Jaffe reaction, the reaction of creatinine and picric acid in an alkaline solution, followed by quantitation of the colorimetric readout using a spectrophotometer at 520 nm." [http://en.wikipedia.org/wiki/Jaffe_reaction "Wikipedia"]
synonym: "alkaline picrate creatinine assay with spectrophotometric readout" EXACT []
synonym: "Jaffe reaction creatinine assay with spectrophotometric readout" EXACT []
xref: PMID:13072520
is_a: MMO:0000270 ! blood creatinine analysis
is_a: MMO:0000541 ! creatinine analysis by liquid phase colorimetry with spectrophotometric readout
created_by: JSmith
creation_date: 2014-06-10T13:41:17Z

[Term]
id: MMO:0000543
name: urine creatinine analysis by Jaffe reaction with spectrophotometric readout
def: "A method for assaying creatinine in urine using the Jaffe reaction, the reaction of creatinine and picric acid in an alkaline solution, followed by quantitation of the colorimetric readout using a spectrophotometer at 520 nm." [http://en.wikipedia.org/wiki/Jaffe_reaction "Wikipedia"]
synonym: "alkaline picrate urine creatinine assay with spectrophotometric readout" EXACT []
synonym: "Jaffe reaction urine creatinine assay with spectrophotometric readout" EXACT []
is_a: MMO:0000275 ! urine creatinine analysis
is_a: MMO:0000542 ! creatinine analysis by Jaffe reaction with spectrophotometric readout
created_by: JSmith
creation_date: 2014-06-10T13:43:17Z

[Term]
id: MMO:0000544
name: plasma creatinine analysis by Jaffe reaction with spectrophotometric readout
def: "A method for assaying the creatinine in plasma (the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended) using the Jaffe reaction, the reaction of creatinine and picric acid in an alkaline solution, followed by quantitation of the colorimetric readout using a spectrophotometer at 520 nm. The assay can be performed without the removal of proteins from the sample, or in combination with such removal which reduces the possibility of interference from proteinaceous chromogens." [http://en.wikipedia.org/wiki/Jaffe_reaction "Wikipedia"]
synonym: "alkaline picrate plasma creatinine assay with spectrophotometric readout" EXACT []
synonym: "Jaffe reaction plasma creatinine assay with spectrophotometric readout" EXACT []
xref: PMID:13072520
is_a: MMO:0000306 ! plasma creatinine analysis
is_a: MMO:0000542 ! creatinine analysis by Jaffe reaction with spectrophotometric readout
created_by: JSmith
creation_date: 2014-06-10T13:46:18Z

[Term]
id: MMO:0000545
name: plasma creatinine analysis by Jaffe reaction without deproteinization with spectrophotometric readout
def: "A method for assaying the creatinine in blood plasma from which excess proteins have not been removed, using the Jaffe reaction, the reaction of creatinine and picric acid in an alkaline solution, followed by quantitation of the colorimetric readout using a spectrophotometer at 520 nm." [http://en.wikipedia.org/wiki/Jaffe_reaction "Wikipedia"]
synonym: "Jaffe reaction plasma creatinine assay with spectrophotometric readout, without deproteinization" EXACT []
is_a: MMO:0000544 ! plasma creatinine analysis by Jaffe reaction with spectrophotometric readout
created_by: JSmith
creation_date: 2014-06-10T13:49:29Z

[Term]
id: MMO:0000546
name: plasma creatinine analysis by Jaffe reaction with deproteinization and spectrophotometric readout
def: "A method for assaying the creatinine in deproteinized plasma (that is, blood plasma from which excess proteins have been removed) using the Jaffe reaction, the reaction of creatinine and picric acid in an alkaline solution, followed by quantitation of the colorimetric readout using a spectrophotometer at 520 nm." [http://en.wikipedia.org/wiki/Jaffe_reaction "Wikipedia"]
synonym: "Jaffe reaction plasma creatinine assay with spectrophotometric readout, with deproteinization" EXACT []
is_a: MMO:0000544 ! plasma creatinine analysis by Jaffe reaction with spectrophotometric readout
created_by: JSmith
creation_date: 2014-06-10T13:53:28Z

[Term]
id: MMO:0000547
name: ophthalmoscopy
def: "Any examination of one or both eyes using an ophthalmoscope, an instrument containing a perforated mirror and lenses used to examine the interior of the eye, for instance, the retina." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "visual assessment with an ophthalmoscope" NARROW []
is_a: MMO:0000026 ! in vivo method
created_by: JSmith
creation_date: 2014-06-11T15:16:01Z

[Term]
id: MMO:0000548
name: indirect ophthalmoscopy
def: "Ophthalmoscopy using an ophthalmoscope with a hand-held lens positioned close to the subject's eye that produces an inverted, or reversed, image of two to five times magnification." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "visual assessment with an indirect ophthalmoscope" NARROW []
is_a: MMO:0000547 ! ophthalmoscopy
created_by: JSmith
creation_date: 2014-06-11T15:17:47Z

[Term]
id: MMO:0000549
name: direct ophthalmoscopy
def: "Ophthalmoscopy using an ophthalmoscope that produces an upright, or unreversed, image of the interior of the eye at approximately 15 times magnification." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "visual assessment with a direct ophthalmoscope" NARROW []
is_a: MMO:0000547 ! ophthalmoscopy
created_by: JSmith
creation_date: 2014-06-11T15:17:52Z

[Term]
id: MMO:0000550
name: slit-lamp ophthalmoscopy
def: "Examination of the eyes using a slit-lamp, an instrument in which a high-intensity beam of light is projected through a narrow slit, and a cross section of the illuminated part of the eye is examined through a magnifying lens, allowing visualization of the external, surface, and internal segments of the eye, including the eyelid(s), lashes, conjunctiva, cornea, anterior chamber, pupil, iris, vitreous and, when a secondary lens is used, the retina." [Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000547 ! ophthalmoscopy
created_by: JSmith
creation_date: 2014-06-11T15:21:18Z

[Term]
id: MMO:0000551
name: slit-lamp direct ophthalmoscopy
def: "Direct ophthalmoscopy utilizing a slit lamp or slit-lamp apparatus, an instrument in which a high-intensity beam of light is projected through a narrow slit for observation of the external, surface, and internal segments of the eye viewed as an upright, or unreversed, image." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "visual assessment with a direct slit-lamp ophthalmoscope" NARROW []
is_a: MMO:0000549 ! direct ophthalmoscopy
is_a: MMO:0000550 ! slit-lamp ophthalmoscopy
created_by: JSmith
creation_date: 2014-06-11T15:41:28Z

[Term]
id: MMO:0000552
name: slit-lamp indirect ophthalmoscopy
def: "Indirect ophthalmoscopy utilizing a slit lamp or slit-lamp apparatus, an instrument in which a high-intensity beam of light is projected through a narrow slit for observation of the interior, particularly the retina, of the eye. In indirect ophthalmoscopy the observer uses a hand-held lens, positioned close to the subject's eye, that produces an inverted or reversed image." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "visual assessment with an indirect slit-lamp ophthalmoscope" NARROW []
is_a: MMO:0000548 ! indirect ophthalmoscopy
is_a: MMO:0000550 ! slit-lamp ophthalmoscopy
created_by: JSmith
creation_date: 2014-06-11T15:43:40Z

[Term]
id: MMO:0000553
name: automated plasma analysis
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the physical or chemical characteristics of plasma, the fluid portion of the blood remaining after cells and platelets are removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000179 ! automated blood analysis
created_by: JSmith
creation_date: 2014-06-11T16:18:19Z

[Term]
id: MMO:0000554
name: automated serum analysis
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the physical or chemical characteristics of  serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000179 ! automated blood analysis
created_by: JSmith
creation_date: 2014-06-11T16:19:30Z

[Term]
id: MMO:0000555
name: automated plasma analysis using Beckman analyzer
def: "Method using a device manufactured by the Beckman or Beckman Coulter company and designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the physical or chemical characteristics of plasma." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
synonym: "plasma analysis by Beckman autoanalyzer method" RELATED []
is_a: MMO:0000553 ! automated plasma analysis
created_by: JSmith
creation_date: 2014-06-11T16:20:42Z

[Term]
id: MMO:0000556
name: automated serum electrolyte analysis
def: "Automated analysis of one or more electrolytes, substances which dissociate into ions, in blood serum." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000037 ! automated blood electrolyte analysis
is_a: MMO:0000554 ! automated serum analysis
created_by: JSmith
creation_date: 2014-06-11T16:22:26Z

[Term]
id: MMO:0000557
name: peptide analysis by liquid phase colorimetry with spectrophotometric readout
def: "Method of assessing the amount of one or more peptides, low molecular weight compounds composed of at least two amino acids joined by peptide linkages, in a solution using a technique in which the color of that solution, usually after a chemical or enzymatic reaction, is evaluated based on its ability to alter the transmission of light at specific wavelengths in the visible spectrum, that is, to alter the transmission of a specific color of light, using a spectrophotometer." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, McGraw-Hill:McGraw-Hill_Dictionary_of_Scientific_and_Technical_Terms--4th_Ed, Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000173 ! spectrophotometry
is_a: MMO:0000330 ! peptide/protein analysis by liquid phase colorimetry
created_by: JSmith
creation_date: 2014-06-12T11:57:37Z

[Term]
id: MMO:0000558
name: reduced glutathione/oxidized glutathione enzyme recycling assay
def: "A method which uses the sequential reduction of glutathione using the enzyme glutathione reductase, and oxidation using DTNB (5,5'-dithiobis(2-nitrobenzoic acid)) to produce the yellow product TNB (5-mercapto-2-nitrobenzoic acid) that can be quantitated using a spectrophotometer. The process of recycling the glutathione through multiple rounds of reduction and oxidation increases the sensitivity of the assay. The assay can be used to measure total reduced and oxidized glutathione (GSH + GSSG) or, by initially masking the endogenous GSH, the differential levels of the two components." [http://www.dojindo.com/store/p/205-Total-Glutathione-Quantification-Kit.html "Website"]
synonym: "GSH/GSSG enzyme recycling assay" RELATED []
is_a: MMO:0000557 ! peptide analysis by liquid phase colorimetry with spectrophotometric readout
created_by: JSmith
creation_date: 2014-06-12T12:11:19Z

[Term]
id: MMO:0000559
name: defensive burying test
def: "A method which utilizes a chamber in which one or more noxious substances or aversive stimulus-inducing devices, such as an electrified shock probe are located, and in which a movable material such as wood bedding or sand is available. Test subjects are observed burying the adverse stimulus under the movable material, presumably as a defensive or protective response." [PMID:572863, PMID:6117086]
synonym: "defensive burying apparatus method" RELATED []
synonym: "defensive burying chamber method" RELATED []
is_a: MMO:0000256 ! movement/behavior test enclosure method
created_by: JSmith
creation_date: 2014-11-05T13:50:46Z

[Term]
id: MMO:0000560
name: ex vivo light microscopy with histochemistry and digital image analysis
def: "A method performed outside the living body, for instance, on isolated cells or tissues, which incorporates the use of light microscopy and histochemistry to produce picture files stored as data expressed in a discrete numerical form, followed by use of computer software to evaluate these resulting microscopic images." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed]
is_a: MMO:0000220 ! ex vivo light microscopy with digital image analysis
is_a: MMO:0000561 ! ex vivo light microscopy with histochemistry
created_by: JSmith
creation_date: 2015-05-01T11:34:14Z

[Term]
id: MMO:0000561
name: ex vivo light microscopy with histochemistry
def: "A method performed outside the living body, for instance, on isolated cells or tissues, which incorporates the use of light microscopy and histochemistry to produce magnified images. Histochemistry is the microscopic analysis of tissues stained with chemical agents to increase the contrast and aid visualization or to highlight specific substances within the specimen." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, http://en.wikipedia.org/wiki/Histology#Staining "Wikipedia", ISBN:978-1416049982]
is_a: MMO:0000111 ! ex vivo light microscopy
is_a: MMO:0000497 ! histochemistry
created_by: JSmith
creation_date: 2015-05-01T11:34:14Z

[Term]
id: MMO:0000562
name: ex vivo microbiological method
def: "A procedure or technique performed outside the living body of a higher organism by which properties of microorganisms, e.g. infectious agents such as bacteria, fungi or parasites, and their effects on other living organisms is assessed and a quantitative or qualitative value assigned." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:22654893]
synonym: "ex vivo bacteriology method" NARROW []
synonym: "ex vivo microbiology method" EXACT []
is_a: MMO:0000027 ! ex vivo method
created_by: JSmith
creation_date: 2015-05-01T11:52:41Z

[Term]
id: MMO:0000563
name: plate count
def: "The enumeration of individual colonies in a microbial/bacterial culture by distributing a solution containing the microorganisms, either straight or (more commonly) as a set of serial dilutions, onto a dish containing a base layer of growth medium plus a gelling agent such as agar. At an appropriate dilution, each viable microorganism will divide to form an individual, clonal colony. The number of colonies on each plate is counted and, using the volume and dilution of the plated sample, the absolute number or the concentration of microbes in the original sample is calculated." [Farlex:Medical_Dictionary_for_the_Health_Professions_and_Nursing_2012, http://en.wikipedia.org/wiki/Colony-forming_unit#Tools_for_counting_colonies "Wikipedia"]
synonym: "colony count" RELATED []
synonym: "colony counting method" RELATED []
synonym: "plate counting method" EXACT []
is_a: MMO:0000562 ! ex vivo microbiological method
created_by: JSmith
creation_date: 2015-05-01T11:55:30Z

[Term]
id: MMO:0000564
name: plate count using selective/restrictive growth conditions
def: "A plate colony counting method that uses conditions which differentially effect the ability of different types of microorganisms to grow. Examples would include addition of antibiotics to or removal of essential chemical components such as amino acids from the growth medium, and incubating the plates at a temperature which is restrictive for certain organisms and/or particularly advantageous for others." [http://en.wikipedia.org/wiki/Colony-forming_unit#Tools_for_counting_colonies "Wikipedia", http://en.wikipedia.org/wiki/Growth_medium#Selective_media "Wikipedia"]
synonym: "colony counting method using selective/restrictive growth conditions" RELATED []
synonym: "differential colony count" RELATED []
synonym: "plate counting method using selective/restrictive growth conditions" EXACT []
synonym: "selective colony count" RELATED []
is_a: MMO:0000563 ! plate count
created_by: JSmith
creation_date: 2015-05-01T16:13:36Z

[Term]
id: MMO:0000565
name: plate count using Todd-Hewitt yeast extract agar plates
def: "A plate colony counting method that uses Todd-Hewitt yeast extract (THY) agar which are selective for certain bacterial species/strains such as Streptococcus pneumoniae." [PMID:20715928]
synonym: "colony count using THY agar plates" RELATED []
synonym: "plate count using THY agar plates" RELATED []
is_a: MMO:0000564 ! plate count using selective/restrictive growth conditions
created_by: JSmith
creation_date: 2015-05-04T12:43:13Z

[Term]
id: MMO:0000566
name: plate count using supplemented brain-heart infusion/vancomycin plates
def: "A plate colony counting method that uses supplemented brain-heart infusion (sBHI) agar plates to which hemin/heme, nicotinamide adenine dinucleotide (NAD) and the antibiotic vancomycin have been added. SBHI/vancomycin plates support the growth of fastidious bacteria with an obligate requirement for heme and beta-NAD such as various strains of Haemophilus influenzae, and prevent the growth of vancomycin-sensitive bacteria such as Streptococcus pneumoniae." [PMID:20715928]
synonym: "colony count using sBHI/vancomycin plates" RELATED []
synonym: "plate count using SBHI/vancomycin plates" RELATED []
is_a: MMO:0000564 ! plate count using selective/restrictive growth conditions
created_by: JSmith
creation_date: 2015-05-04T12:44:02Z

[Term]
id: MMO:0000567
name: rotarod performance test
def: "A method that utilizes a device consisting of a rotating rod the speed of which is mechanically driven and precisely controlled, for instance held constant or accelerated. The rotarod test is often used to measure riding time or endurance in order to evaluate balance, motor coordination or grip strength." [https://en.wikipedia.org/wiki/Rotarod_performance_test "Wikipedia"]
is_a: MMO:0000588 ! balance, coordination or strength assessment method
created_by: jesmith
creation_date: 2016-04-25T16:12:34Z

[Term]
id: MMO:0000568
name: ex vivo volume measurement calculated from measurement of weight
def: "Method whereby an object or substance is weighed and the volume of (that is, the size of the three dimensional space occupied by) that object or substance is derived based on the measured weight and the density of the substance." [American_Heritage:The_American_Heritage_Science_Dictionary_2005]
is_a: MMO:0000212 ! ex vivo volume measurement method
created_by: jesmith
creation_date: 2016-05-02T13:20:45Z

[Term]
id: MMO:0000569
name: ex vivo volume measurement calculated from change in weight
def: "Method whereby an object or substance is weighed more than once, for example at different times or on different days, and the volume or a change in the volume of (that is, the size of the three dimensional space occupied by) that object or substance is derived based on the measured weights and the density of the substance." [American_Heritage:The_American_Heritage_Science_Dictionary_2005]
is_a: MMO:0000568 ! ex vivo volume measurement calculated from measurement of weight
created_by: jesmith
creation_date: 2016-05-02T13:30:32Z

[Term]
id: MMO:0000570
name: micro-computed tomography
def: "High-resolution computed tomography in which the pixel sizes of the cross-sections are in the micrometer range." [PMID:25292366]
synonym: "high-resolution computed tomography" RELATED []
synonym: "high-resolution x-ray tomography" RELATED []
synonym: "microcomputed tomography" EXACT []
synonym: "micro-CT" RELATED []
synonym: "X-ray microtomography" RELATED []
is_a: MMO:0000128 ! computed tomography
created_by: jesmith
creation_date: 2016-08-01T12:23:34Z

[Term]
id: MMO:0000571
name: fear conditioning test
def: "A test in which an aversive stimulus is administered, either paired one or more times with a neutral stimulus followed by assessment of subsequent fear/emotion-based reactions in response to the neutral stimulus alone (cued) or within a certain environment or context followed by assessment of subsequent fear/emotion-based reactions in that environment without the aversive stimulus (contextual)." [https://www.ncbi.nlm.nih.gov/books/NBK5223/ "Website"]
is_a: MMO:0000256 ! movement/behavior test enclosure method
created_by: jesmith
creation_date: 2017-02-22T17:51:58Z

[Term]
id: MMO:0000572
name: contextual fear conditioning test
def: "A test in which an aversive stimulus is administered within a certain environment or context followed by assessment of subsequent fear/emotion-based reactions in that environment without the aversive stimulus." [https://www.ncbi.nlm.nih.gov/books/NBK5223/ "Website"]
is_a: MMO:0000571 ! fear conditioning test
created_by: jesmith
creation_date: 2017-02-22T18:00:32Z

[Term]
id: MMO:0000573
name: cued fear conditioning test
def: "A test in which an aversive stimulus is administered paired one or more times with a neutral stimulus followed by assessment of subsequent fear/emotion-based reactions in response to the neutral stimulus alone." [https://www.ncbi.nlm.nih.gov/books/NBK5223/ "Website"]
is_a: MMO:0000571 ! fear conditioning test
created_by: jesmith
creation_date: 2017-02-22T18:00:35Z

[Term]
id: MMO:0000574
name: forced swim test
def: "Test in which an animal is placed in a tank of water without platforms and behaviors (such as swimming, climbing and floating) are assessed for a set period of time." [PMID:22555240]
synonym: "forced swimming test" EXACT []
synonym: "Porsolt forced swim test" RELATED []
is_a: MMO:0000256 ! movement/behavior test enclosure method
created_by: jesmith
creation_date: 2017-02-22T18:08:22Z

[Term]
id: MMO:0000575
name: computational method
def: "A method whereby a value or values are achieved largely or completely via calculations, such as statistical calculations or application of simple or complex algorithms for analysis." [http://mathworld.wolfram.com/Computation.html "Website"]
is_a: MMO:0000000 ! measurement method
created_by: jesmith
creation_date: 2017-02-23T18:08:28Z

[Term]
id: MMO:0000576
name: Kaplan-Meier estimate
def: "A statistical method for determining the probability of surviving for a given length of time while considering time in many small intervals." [PMID:21455458]
synonym: "Kaplan-Meier inference" RELATED []
synonym: "Kaplan-Meier survival analysis" RELATED []
synonym: "Kaplan-Meier survival curve" RELATED []
is_a: MMO:0000575 ! computational method
created_by: jesmith
creation_date: 2017-02-23T18:09:24Z

[Term]
id: MMO:0000577
name: intra-aortic radiotelemetry
def: "A method which utilizes a  measurement device implanted in any part of the aorta which transmits radio signals to a recording device." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "intra-aortic radiotelemetric implant" RELATED []
is_a: MMO:0000015 ! radiotelemetry
created_by: jesmith
creation_date: 2017-03-16T11:20:22Z

[Term]
id: MMO:0000578
name: intra-aortic thoracic radiotelemetry
def: "A method which utilizes a  measurement device implanted in the thoracic aorta which transmits radio signals to a recording device." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "intra-aortic thoracic radiotelemetric implant" RELATED []
is_a: MMO:0000577 ! intra-aortic radiotelemetry
created_by: jesmith
creation_date: 2017-03-16T11:22:17Z

[Term]
id: MMO:0000579
name: intra-aortic thoracic radiotelemetry via carotid cannulation
def: "A method which utilizes an implanted measurement device to transmit radio signals to a recording device, where the device is implanted in the thoracic aorta using a cannula inserted through the carotid artery." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "intra-aortic thoracic radiotelemetric implant inserted by carotid cannulation" RELATED []
is_a: MMO:0000578 ! intra-aortic thoracic radiotelemetry
created_by: jesmith
creation_date: 2017-03-16T11:37:59Z

[Term]
id: MMO:0000580
name: intra-aortic abdominal radiotelemetry via femoral cannulation
def: "A method which utilizes an implanted measurement device to transmit radio signals to a recording device, where the device is implanted in the abdominal aorta using a cannula inserted through the femoral artery." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "intra-aortic abdominal radiotelemetric implant inserted by femoral cannulation" RELATED []
is_a: MMO:0000070 ! intra-aortic abdominal radiotelemetry
created_by: jesmith
creation_date: 2017-03-16T11:42:30Z

[Term]
id: MMO:0000581
name: intra-aortic abdominal radiotelemetry via abdominal aorta cannulation
def: "A method which utilizes an implanted measurement device to transmit radio signals to a recording device, where the device is implanted directly in the abdominal aorta using a cannula inserted through the abdominal aorta." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "intra-aortic abdominal radiotelemetric implant with direct aorta cannulation" RELATED []
is_a: MMO:0000070 ! intra-aortic abdominal radiotelemetry
created_by: jesmith
creation_date: 2017-03-16T13:33:21Z

[Term]
id: MMO:0000582
name: intra-carotid radiotelemetry
def: "A method which utilizes a  measurement device implanted in one of the common carotid arteries (that is, the two main arteries which supply oxygenated blood to the head before each bifurcates into an internal and an external carotid artery)  which transmits radio signals to a recording device." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, https://en.wikipedia.org/wiki/Common_carotid_artery "Wikipedia", ISBN:978-1416049982]
synonym: "intracarotid radiotelemetry" EXACT []
is_a: MMO:0000015 ! radiotelemetry
created_by: jesmith
creation_date: 2017-05-16T14:41:16Z

[Term]
id: MMO:0000583
name: ex vivo analysis of atomic composition
def: "A procedure or technique performed outside the living body by which the atomic composition, that is, the relative or absolute amounts of one or more specific elements in a sample are measured." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--5th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982]
synonym: "ex vivo chemical analysis" BROAD []
is_a: MMO:0000027 ! ex vivo method
created_by: jesmith
creation_date: 2017-08-10T16:55:16Z

[Term]
id: MMO:0000584
name: ex vivo analysis of atomic composition following dry ashing
def: "A procedure or technique performed outside the living body by which the atomic composition, that is, the relative or absolute amounts of one or more specific elements in a sample that has been subjected to dry ashing. Dry ashing is defined as the heating of a substance to leave only noncombustible ash, usually performed by placing the sample in an open inert vessel and destroying the combustible (organic) portion of the sample by thermal decomposition." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--5th_Ed, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, https://www.inorganicventures.com/ashing-sample-preparation-procedures "Website", ISBN:978-1416049982]
synonym: "dry ashing with analysis of atomic composition" EXACT []
is_a: MMO:0000583 ! ex vivo analysis of atomic composition
created_by: jesmith
creation_date: 2017-08-10T17:05:01Z

[Term]
id: MMO:0000585
name: flame atomic emission spectrometry following dry ashing
def: "A method in which a sample is reduced to noncombustible ash followed by the measurement of its atomic composition by atomic emission spectrometry." [https://www.inorganicventures.com/ashing-sample-preparation-procedures "Website", McGraw-Hill:McGraw-Hill_Dictionary_of_Scientific_and_Technical_Terms--4th_Ed]
synonym: "dry ashing followed by flame photometry" RELATED []
synonym: "flame photometry following dry ashing" RELATED []
is_a: MMO:0000039 ! flame atomic emission spectrometry
is_a: MMO:0000584 ! ex vivo analysis of atomic composition following dry ashing
created_by: jesmith
creation_date: 2017-08-10T17:12:23Z

[Term]
id: MMO:0000586
name: wildness/tameness assessment method
def: "Any method to assess wildness, tameness, placidity and/or ease of handling of animals, for example, laboratory animals." [RGD:JRS]
synonym: "wildness test" RELATED []
is_a: MMO:0000254 ! body movement/behavior method
created_by: jesmith
creation_date: 2017-12-08T16:04:09Z

[Term]
id: MMO:0000587
name: wildness assessment scale method
def: "A method by which wildness and ease of handling of animals, for example, laboratory animals, is assessed and a score or grade on a specified scale is assigned." [PMID:12884964]
synonym: "wildness/placidity rating scale method" RELATED []
is_a: MMO:0000586 ! wildness/tameness assessment method
created_by: jesmith
creation_date: 2017-12-08T16:06:45Z

[Term]
id: MMO:0000588
name: balance, coordination or strength assessment method
def: "Any method to assess the ability to maintain bodily equilibrium, the ability to control the movements of the parts of the body so they function harmoniously, and/or the ability to produce or resist a physical force." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--5th_Ed, Macmillan:The_Macmillan_Online_Dictionary_of_American_English, Mosby:Mosbys_Medical_Dictionary--9th_Ed]
is_a: MMO:0000254 ! body movement/behavior method
created_by: jesmith
creation_date: 2017-12-08T16:09:41Z

[Term]
id: MMO:0000589
name: grid test
def: "A method used to measure motor coordination and limb movement at different angles depending on the  configuration of the grid." [MPD:MB]
is_a: MMO:0000588 ! balance, coordination or strength assessment method
created_by: jesmith
creation_date: 2017-12-14T10:44:17Z

[Term]
id: MMO:0000590
name: parallel rod floor apparatus method
def: "A method used to assess motor coordination and balance whereby a clear acrylic box sits on top of a parallel rod floor made of conductive metal which is slightly above a base metal plate.  Foot slips (errors) are recorded when an electrical circuit is completed; used to assess effects of alcohol or other substances; a built-in activity monitor may record distance traveled." [https://www.stoeltingco.com/parallel-rod-floor-apparatus.html "Website", MPD:MB]
is_a: MMO:0000256 ! movement/behavior test enclosure method
is_a: MMO:0000588 ! balance, coordination or strength assessment method
created_by: jesmith
creation_date: 2017-12-14T10:47:49Z

[Term]
id: MMO:0000591
name: activity monitoring apparatus method
def: "A method using an enclosure equipped with infrared beams to monitor and measure movement; the apparatus may contain monitors for oxygen consumption and carbon dioxide production as well." [MPD:MB]
is_a: MMO:0000256 ! movement/behavior test enclosure method
created_by: jesmith
creation_date: 2017-12-14T10:50:14Z

[Term]
id: MMO:0000592
name: conditioned placed preference test
def: "A method that is a form of Pavlovian conditioning used to measure the motivational effects of objects or experiences on a test subject." [MPD:MB]
is_a: MMO:0000256 ! movement/behavior test enclosure method
created_by: jesmith
creation_date: 2017-12-14T10:51:39Z

[Term]
id: MMO:0000593
name: endurance swim test
def: "A test in which an animal is placed in a tank of water without platforms; swimming endurance is measured for a set period of time." [MPD:MB]
is_a: MMO:0000574 ! forced swim test
created_by: jesmith
creation_date: 2017-12-14T12:00:26Z

[Term]
id: MMO:0000594
name: go/no-go task
def: "A pass/fail test used to measure a subject's capacity for sustained attention and response control; a test is passed when the go condition is met and also the no-go condition fails." [MPD:MB]
is_a: MMO:0000256 ! movement/behavior test enclosure method
created_by: jesmith
creation_date: 2017-12-14T12:01:55Z

[Term]
id: MMO:0000595
name: hole-board test
def: "A test utilizing an enclosure consisting of a single area bordered by clear or opaque walls with the floor of the apparatus containing holes that the test subject can explore; interpreted as measuring exploratory and/or anxiety-related behaviors." [MPD:MB, RGD:JRS]
is_a: MMO:0000256 ! movement/behavior test enclosure method
created_by: jesmith
creation_date: 2017-12-14T12:02:59Z

[Term]
id: MMO:0000596
name: home cage monitoring method
def: "A test used to measure and/or record movement or behavior of a test subject in its home cage." [MPD:MB]
is_a: MMO:0000256 ! movement/behavior test enclosure method
created_by: jesmith
creation_date: 2017-12-14T12:05:35Z

[Term]
id: MMO:0000597
name: light-dark box test
def: "A test utilizing an enclosure where typically 2/3 of the apparatus is brightly lit and in the open, and 1/3 is covered and in the dark; used to measure exploratory and anxiety-related behaviors of a test subject." [MPD:MB]
is_a: MMO:0000256 ! movement/behavior test enclosure method
created_by: jesmith
creation_date: 2017-12-14T12:07:13Z

[Term]
id: MMO:0000598
name: SHIRPA test
def: "The SmithKline Beecham, Harwell, Imperial College, Royal London Hospital, Phenotype Assessment method; a standardized battery of tests to assess muscle, cerebellar, sensory and neuropsychiatric functions in laboratory animals." [https://en.wikipedia.org/wiki/SHIRPA "Wikipedia"]
is_a: MMO:0000256 ! movement/behavior test enclosure method
created_by: jesmith
creation_date: 2017-12-14T12:10:39Z

[Term]
id: MMO:0000599
name: modified SHIRPA test
def: "A variation of the standardized SHIRPA test utilizing a viewing jar and/or an arena to assess muscle function, cerebellar function, sensory function, neuropsychiatric function, and dysmorphology by experimenter observation." [https://en.wikipedia.org/wiki/SHIRPA "Wikipedia", MPD:MB]
is_a: MMO:0000598 ! SHIRPA test
created_by: jesmith
creation_date: 2017-12-14T12:14:53Z

[Term]
id: MMO:0000600
name: observational fear learning apparatus method
def: "A method using an enclosure with two chambers separated by a transparent partition whereby one of the chambers is equipped with foot shock capability; the test subject is able to observe the reaction of another subject receiving a shock." [MPD:MB]
is_a: MMO:0000256 ! movement/behavior test enclosure method
created_by: jesmith
creation_date: 2017-12-14T12:18:08Z

[Term]
id: MMO:0000601
name: operant conditioning chamber method
def: "A method to study behavior conditioning by teaching a subject to perform certain tasks (like pressing a lever) in response to certain stimuli (like light or sound); the chamber mechanism delivers a reward in response to a correct response and/or a punishment in response to an incorrect response." [MPD:MB]
is_a: MMO:0000256 ! movement/behavior test enclosure method
created_by: jesmith
creation_date: 2017-12-14T12:20:22Z

[Term]
id: MMO:0000602
name: five-choice serial-reaction time task
def: "A method using an operant chamber equipped with five holes, which can illuminate, and a food tray to deliver a reward; used to assess visuospatial attention and impulsivity." [MPD:MB]
is_a: MMO:0000601 ! operant conditioning chamber method
created_by: jesmith
creation_date: 2017-12-14T12:22:33Z

[Term]
id: MMO:0000603
name: puzzle box apparatus method
def: "A method used to assess the motivation of a subject to solve problems when exposed to an arena unequally partitioned into two compartments, a larger, brightly-lit compartment which is usually the start box and a smaller, dark compartment which is the goal box. The entrance to the smaller compartment can be blocked with a number of 'obstacles' which the animal must navigate or remove to reach the goal box." [https://mazeengineers.com/portfolio/puzzle-box/ "Website"]
synonym: "puzzle box test" EXACT []
is_a: MMO:0000256 ! movement/behavior test enclosure method
created_by: jesmith
creation_date: 2017-12-14T12:28:40Z

[Term]
id: MMO:0000604
name: three-chamber assay
def: "A test utilizing an enclosure divided into three parts, used to assess a subject's reactivity to novel or familiar objects;  in this context 'objects'may be inanimate or another organism, typically of the same species." [MPD:MB]
is_a: MMO:0000256 ! movement/behavior test enclosure method
created_by: jesmith
creation_date: 2017-12-14T12:42:22Z

[Term]
id: MMO:0000605
name: three-chamber sociability and social novelty test
def: "A three-chamber assay in which the test subject is first acclimated to the apparatus then subjected to two test scenarios, the first in which one of the three chambers contains a novel animal of the same species which the third chamber is empty, followed by a second in which that same previously-novel animal is again presented in chamber two and another 'never-before-met intruder' is presented in chamber three." [http://med.stanford.edu/sbfnl/services/bm/si/three-chamber.html "Website"]
is_a: MMO:0000604 ! three-chamber assay
created_by: jesmith
creation_date: 2017-12-14T12:45:25Z

[Term]
id: MMO:0000606
name: visual cliff apparatus method
def: "A method used to test depth perception and assess anxiety-related behaviors; the apparatus consists a a sheet of clear acrylic that covers a cloth with a high-contrast checkerboard pattern; one end of the cloth is placed immediately beneath the acrylic sheet while the other end is placed below the acrylic sheet, giving the appearance of depth while protecting the subject from actually falling." [MPD:MB]
is_a: MMO:0000256 ! movement/behavior test enclosure method
created_by: jesmith
creation_date: 2017-12-14T12:50:46Z

[Term]
id: MMO:0000607
name: visual water box method
def: "A method used to test visual discrimination, pattern discrimination, and visual acuity in rodents; this test combines the basic principles of a discrimination box and the Morris water maze." [MPD:MB]
is_a: MMO:0000256 ! movement/behavior test enclosure method
created_by: jesmith
creation_date: 2017-12-14T12:52:38Z

[Term]
id: MMO:0000608
name: Barnes circular maze test
def: "A method that utilizes an enclosure made up of a circular surface with up to 20 holes (one is an escape hole); visual cues are placed outside the enclosure but in full view of the test subject.  The test requires that an test subject makes a choice or a series of choices and/or learn a specific solution to the problem of escaping; used to test spatial learning and memory." [MPD:MB]
is_a: MMO:0000257 ! movement/behavior test maze method
created_by: jesmith
creation_date: 2017-12-14T12:53:47Z

[Term]
id: MMO:0000609
name: elevated Y-maze apparatus method
def: "A method utilizing an experimental apparatus consisting of three arms of equal length in the shape of a Y elevated a set distance above the floor or above the platform on which the apparatus sits, and upon which the test subject can walk; used to study how rodents function with memory and spatial learning; it is also used as a spontaneous alternation task to assess novelty seeking." [MPD:MB]
synonym: "elevated Y-maze apparatus test" RELATED []
is_a: MMO:0000257 ! movement/behavior test maze method
created_by: jesmith
creation_date: 2017-12-14T12:59:13Z

[Term]
id: MMO:0000610
name: isolated body part material fatigue test
def: "A technique performed on an isolated body part consisting of a solid material, for instance a bone, to assign a quantitative or qualitative value for fatigue limit. An isolated body part is a subdivision of the material or physical structure of an organism, such as an organ, extremity or tissue, after it has been removed from the body." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, MPD:MB]
synonym: "ex vivo material fatigue test" RELATED []
is_a: MMO:0000004 ! isolated body part method
created_by: jesmith
creation_date: 2018-01-16T16:17:29Z

[Term]
id: MMO:0000611
name: bone material fatigue test
def: "A method performed on bone to assign a quantitative or qualitative value for fatigue limit." [MPD:MB, RGD:JRS]
is_a: MMO:0000396 ! isolated bone method
is_a: MMO:0000610 ! isolated body part material fatigue test
created_by: jesmith
creation_date: 2018-01-16T16:25:52Z

[Term]
id: MMO:0000612
name: in vivo body part measuring method
def: "A procedure or technique performed in or on an intact body, especially a living body, by which a morphological parameter of some part or subdivision of that body is assessed and a quantitative or qualitative value assigned." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, ISBN:978-1416049982, PMID:22654893]
is_a: MMO:0000119 ! body measuring method
created_by: jesmith
creation_date: 2018-01-16T16:36:19Z

[Term]
id: MMO:0000613
name: tail length measuring method
def: "A method by which the length of the tail, that is, the extent of the tail along its greatest dimension, is measured. The tail is an external caudal extension of the body." [American_Heritage:The_American_Heritage_Dictionary_of_the_English_Language--4th_Ed]
xref: UBERON:0002415
is_a: MMO:0000612 ! in vivo body part measuring method
created_by: jesmith
creation_date: 2018-01-16T16:40:33Z

[Term]
id: MMO:0000614
name: taste threshold test
def: "A method to determine the threshold at which a test subject can detect sweetness, sourness, saltiness or other tastes." [MPD:MB]
is_a: MMO:0000026 ! in vivo method
created_by: jesmith
creation_date: 2018-01-16T16:59:46Z

[Term]
id: MMO:0000615
name: electroconvulsive threshold test
def: "A method used to measure thresholds for minimal clonic, maximal clonic, or psychomotor seizures; commonly used in the screening of anti-epileptic drugs in rodent models." [MPD:MB]
synonym: "ECT" RELATED []
is_a: MMO:0000026 ! in vivo method
created_by: jesmith
creation_date: 2018-01-16T17:17:22Z

[Term]
id: MMO:0000616
name: electroretinography
def: "A method in which electrodes are placed on and/or near the eye, a stimulus is applied and the time course of the response is recorded. This test detects function of the retina (the light-detecting portion of the eye). The retina is comprised of layers of specialized cells, including photoreceptors (rods and cones), that detect light and ganglion cells that transmit images to the brain." [https://en.wikipedia.org/wiki/Electroretinography "Wikipedia", https://www.medicinenet.com/electroretinography/article.htm]
synonym: "ERG" RELATED []
xref: https://eyewiki.aao.org/Electroretinogram
xref: PMID:27384999
is_a: MMO:0000026 ! in vivo method
created_by: jesmith
creation_date: 2018-01-16T17:31:11Z

[Term]
id: MMO:0000617
name: flow cytometry method
def: "A method employed in cell counting, cell sorting, and biomarker detection by suspending cells in a stream of fluid and passing them through an electronic detection apparatus." [https://en.wikipedia.org/wiki/Flow_cytometry "Wikipedia", MPD:MB]
is_a: MMO:0000225 ! automated cell/particle size/count analysis method
created_by: jesmith
creation_date: 2018-01-16T17:37:59Z

[Term]
id: MMO:0000618
name: consumption measuring method
def: "Any method used to quantify intake or ingestion, especially of food or drink." [MPD:MB]
is_a: MMO:0000026 ! in vivo method
created_by: jesmith
creation_date: 2018-01-16T17:42:07Z

[Term]
id: MMO:0000619
name: drink intake measuring method
def: "A method used to quantify the consumption or ingestion of drink, any liquid that is brought into the mouth and swallowed." [MPD:MB]
is_a: MMO:0000618 ! consumption measuring method
created_by: jesmith
creation_date: 2018-01-16T17:47:06Z

[Term]
id: MMO:0000620
name: food intake measuring method
def: "A method used to quantify the consumption or ingestion of food, any solid or semi-solid with nutritional value that is brought into the mouth and swallowed." [https://phenome.jax.org/, https://www.merriam-webster.com/]
is_a: MMO:0000618 ! consumption measuring method
created_by: jesmith
creation_date: 2018-01-16T17:52:03Z

[Term]
id: MMO:0000621
name: laser interference biometry
def: "A method used to measure the anatomical aspects of the eye, including axial length and anterior chamber depth; the device operates as an interferometer and uses infrared laser light to provide repeatable and precise measurements." [MPD:MB]
is_a: MMO:0000026 ! in vivo method
created_by: jesmith
creation_date: 2018-01-16T17:54:35Z

[Term]
id: MMO:0000622
name: ex vivo manometry
def: "A procedure or technique performed outside the living body by which pressure is assessed via the use of a manometer, a gauge consisting of a U-shaped tube which measures and displays the pressure differential between the two ends of the tube." [https://en.wikipedia.org/wiki/Pressure_measurement#Liquid_column_(manometer) "Wikipedia"]
synonym: "manometer method" RELATED []
is_a: MMO:0000027 ! ex vivo method
created_by: jesmith
creation_date: 2018-01-17T13:13:20Z

[Term]
id: MMO:0000623
name: transepidermal water loss test
def: "A method used to measure water loss through the skin using an instrument which consists of two pairs of sensors to measure humidity and temperature gradients just above the skin's surface." [http://www.courage-khazaka.de/index.php/en/products/scientific/139-tewameter "Website", MPD:MB]
synonym: "TEWL test" RELATED []
is_a: MMO:0000026 ! in vivo method
created_by: jesmith
creation_date: 2018-01-17T13:26:05Z

[Term]
id: MMO:0000624
name: tympanometry
def: "A method used to test the condition of the middle ear, including mobility of the tympanic membrane (eardrum) and condition of conduction bones. During the test, a tympanometer is inserted into the ear canal and the instrument causes a series of changes in the pressure in the ear, generates a tone and measures the response of the eardrum at the different pressures." [https://en.wikipedia.org/wiki/Tympanometry "Wikipedia", MPD:MB]
is_a: MMO:0000026 ! in vivo method
created_by: jesmith
creation_date: 2018-01-17T13:35:32Z

[Term]
id: MMO:0000625
name: respiratory mechanics assessment method
def: "A method used to measure in vivo lung function including traditional resistance and compliance measurements; may also include mechanical properties of conducting airways, terminal airways, and parenchyma." [MPD:MB]
is_a: MMO:0000026 ! in vivo method
created_by: jesmith
creation_date: 2018-01-17T14:33:18Z

[Term]
id: MMO:0000626
name: vestibular system assessment method
def: "A method used to measure function of the sensory system that is imperative to the sense of balance and spatial orientation for the purpose of coordinating movement with balance." [MPD:MB]
is_a: MMO:0000588 ! balance, coordination or strength assessment method
created_by: jesmith
creation_date: 2018-01-17T14:38:18Z

[Term]
id: MMO:0000627
name: virtual optometry
def: "A method which employs a virtual reality system to quantify visuomotor behavior, that is, motor activity which is dependent on or involving sight." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, http://www.cerebralmechanics.com/products.html "Website", MPD:MB]
synonym: "OptoMotry method" NARROW []
is_a: MMO:0000254 ! body movement/behavior method
created_by: jesmith
creation_date: 2018-01-17T14:46:36Z

[Term]
id: MMO:0000628
name: in vivo X-ray radiography
def: "An imaging technique using X-rays to view internal structures of a living subject." [MPD:MB]
is_a: MMO:0000124 ! in vivo radiography
created_by: jesmith
creation_date: 2018-01-17T15:27:17Z

[Term]
id: MMO:0000629
name: blood cytokine analysis
def: "Any method which measures one or more cytokines, any of a large group of low-molecular-weight proteins (~5-20 kDa in size) secreted by various cell types. Cytokines are involved in cell-to-cell communication, in coordinating antibody and T cell immune interactions, and in regulating immune reactivity. Cytokines include colony-stimulating factors, interferons, interleukins, lymphokines, and members of the TNF and TGF-beta superfamilies." [https://www.sinobiological.com/Cytokines-information-cytokine.html "Website", Mosby:Mosbys_Medical_Dictionary--9th_Ed, MPD:MB]
comment: Only for use when the specific method of measuring the cytokine such as ELISA, EIA or RIA, is not given.
is_a: MMO:0000166 ! blood protein analysis
created_by: jesmith
creation_date: 2018-01-17T15:35:54Z

[Term]
id: MMO:0000630
name: blood parathyroid hormone analysis
def: "Any method by which the level, concentration or activity in a sample of blood of parathyroid hormone is measured." [MPD:MB]
comment: Only for use when the specific method of measuring the hormone, such as ELISA, EIA or RIA, is not given.
synonym: "blood PTH analysis" RELATED []
is_a: MMO:0000311 ! blood hormone analysis
created_by: jesmith
creation_date: 2018-01-17T15:52:50Z

[Term]
id: MMO:0000631
name: standard blood plasma chemistry panel
def: "A standardized group of  tests which are routinely performed to determine the general health of a patient or test subject, specifically using blood plasma as the input. Plasma is the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, https://labtestsonline.org/tests/chemistry-panels "Website", ISBN:978-1416049982, Miller-Keane:Miller-Keane_Encyclopedia_and_Dictionary_of_Medicine_Nursing_and_Allied_Health--7th_Ed]
is_a: MMO:0000169 ! standard blood chemistry panel
created_by: jesmith
creation_date: 2018-01-17T16:01:36Z

[Term]
id: MMO:0000632
name: standard blood serum chemistry panel
def: "A standardized group of  tests which are routinely performed to determine the general health of a patient or test subject, specifically using blood serum as the input. Serum is the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, https://labtestsonline.org/tests/chemistry-panels "Website", ISBN:978-1416049982]
is_a: MMO:0000169 ! standard blood chemistry panel
created_by: jesmith
creation_date: 2018-01-17T16:06:11Z

[Term]
id: MMO:0000633
name: bronchoalveolar lavage
def: "A technique in which fluid is introduced into the lung(s) then collected for analysis, for example assessment of cells, proteins or pathogens in the lungs." [https://en.wikipedia.org/wiki/Bronchoalveolar_lavage "Wikipedia", https://www.thoracic.org/professionals/clinical-resources/critical-care/clinical-education/critical-care-procedures/bronchoalveolar-lavage.php "Website"]
synonym: "BAL" RELATED []
is_a: MMO:0000235 ! body fluid collection method
created_by: jesmith
creation_date: 2018-01-17T16:09:51Z

[Term]
id: MMO:0000634
name: inulin analysis by liquid phase colorimetry
def: "An assay of inulin content in a liquid sample by colorimetry. Inulin clearance can be used to assess glomerular filtration rate." [PMID:17023465]
is_a: MMO:0000329 ! liquid phase colorimetry
created_by: jesmith
creation_date: 2018-01-18T17:17:32Z

[Term]
id: MMO:0000635
name: inulin analysis by thiourea-resorcinol assay
def: "An assay of inulin content in a liquid sample by the thiourea-resorcinol method, where an orange-red color is formed by the reaction of hydrolyzed inulin with resorinol in strong hydrochloric acid. Inulin clearance can be used to assess glomerular filtration rate." [http://www.jbc.org/content/178/2/839.citation "Journal_Article", PMID:17023465]
synonym: "inulin analysis by resorcinolthiourea assay" RELATED []
is_a: MMO:0000634 ! inulin analysis by liquid phase colorimetry
created_by: jesmith
creation_date: 2018-01-18T17:18:49Z

[Term]
id: MMO:0000636
name: p-aminohippurate analysis by liquid phase colorimetry
def: "An assay to determine p-aminohippurate (PAH) content in a liquid sample by colorimetry. PAH clearance can be used to assess the effective renal plasma flow." [PMID:7849255]
synonym: "PAH analysis by liquid phase colorimetry" RELATED []
is_a: MMO:0000329 ! liquid phase colorimetry
created_by: jesmith
creation_date: 2018-01-18T17:21:40Z

[Term]
id: MMO:0000637
name: micropuncture fluid collection
def: "An in vivo microsurgical preparation that involves the quantitative collection of tubular fluid from a proximal or distal tubule using a micropipette to accurately puncture the specified structure. Used to study single nephron function." [PMCID:PMC2954491]
is_a: MMO:0000235 ! body fluid collection method
created_by: jesmith
creation_date: 2018-01-18T17:25:29Z

[Term]
id: MMO:0000638
name: servo-null micropipette transducer method
def: "A method which utilizes an in vivo microsurgical preparation designed to measure fluid pressures in microscopic structures which can be penetrated by a micropipette. Used to measure hydraulic pressures in glomerular capillaries, kidney tubules, and arterioles." [https://people.rit.edu/lffeee/pressure_flow.pdf "Web_Document"]
synonym: "servo-nulling pressure system method" RELATED []
is_a: MMO:0000026 ! in vivo method
created_by: jesmith
creation_date: 2018-01-18T17:27:39Z

[Term]
id: MMO:0000639
name: molecular method
def: "Any method to determine the nature, properties, or composition of a sample at a subcellular, molecular, atomic or subatomic level." [Mosby:Mosbys_Medical_Dictionary--8th_Ed]
is_a: MMO:0000000 ! measurement method
created_by: jrsmith
creation_date: 2018-05-24T12:16:33Z

[Term]
id: MMO:0000640
name: expression assay
def: "Any method which assesses the process by which products are produced from genes, gene fragments, genetic or genomic loci, etc., including measurement of levels, timing, and/or location, or differential quantification of specific products." [Collins:Collins_Dictionary_of_Biology--3rd_Ed, https://en.wikipedia.org/wiki/Gene_expression "Wikipedia"]
synonym: "expression assay" EXACT DISPLAY_SYNONYM []
synonym: "expression assessment method" RELATED []
synonym: "expression method" RELATED []
is_a: MMO:0000639 ! molecular method
created_by: jrsmith
creation_date: 2018-05-24T12:40:34Z

[Term]
id: MMO:0000641
name: transcript expression assay
def: "Any method which measures the levels, timing, and/or location, or differential quantification of specific gene transcripts, that is, RNA molecules formed from DNA templates during transcription." [https://en.wikipedia.org/wiki/Primary_transcript "Wikipedia", Saunders:Saunders_Comprehensive_Veterinary_Dictionary--3rd_Ed, Segen:Segens_Medical_Dictionary_2012]
synonym: "RNA expression assay" RELATED []
synonym: "transcript expression" EXACT DISPLAY_SYNONYM []
synonym: "transcription profiling assay" RELATED []
xref: OBI:0000424
is_a: MMO:0000640 ! expression assay
created_by: jrsmith
creation_date: 2018-05-24T13:39:43Z

[Term]
id: MMO:0000642
name: protein expression assay
def: "Any method which measures the levels, timing, and/or location of, or differentially quantifies, proteins formed from the translation of gene transcripts." [https://www.nature.com/scitable/topicpage/translation-dna-to-mrna-to-protein-393 "Scitable", PMID:19381602]
synonym: "protein expression" EXACT DISPLAY_SYNONYM []
xref: ECO:0000010
xref: efo:EFO_0001458
xref: OBI:0000615
is_a: MMO:0000640 ! expression assay
created_by: jrsmith
creation_date: 2018-05-28T17:53:57Z

[Term]
id: MMO:0000643
name: in situ expression assay
def: "Any method which assesses an outcome of the process by which products are produced from genes, gene fragments, genetic or genomic loci, etc., including measurement of levels, timing, and/or location, or differential quantification of specific products, when such products are examined in the location (e.g. in a specific tissue, cell or subcellular localization) where the expression occurs." [Collins:Collins_Dictionary_of_Biology--3rd_Ed, https://en.wikipedia.org/wiki/Gene_expression "Wikipedia", https://en.wikipedia.org/wiki/In_situ#Biology_and_biomedical_engineering "Wikipedia"]
synonym: "in situ expression" EXACT DISPLAY_SYNONYM []
is_a: MMO:0000640 ! expression assay
created_by: jrsmith
creation_date: 2018-05-28T17:59:54Z

[Term]
id: MMO:0000644
name: high throughput expression assay
def: "Any method which uses rapid, highly parallel techniques to identify and characterize, for example determine the levels of, a large number of biomolecules (e.g. proteins or RNAs) in a limited number of samples, a limited number of biomolecules in a large number of samples, or a large number of biomolecules in a large number of samples." [https://en.wikipedia.org/wiki/High_throughput_biology "Wikipedia"]
synonym: "high throughput" EXACT DISPLAY_SYNONYM []
is_a: MMO:0000640 ! expression assay
created_by: jrsmith
creation_date: 2018-05-28T18:02:15Z

[Term]
id: MMO:0000645
name: cDNA clone-based transcript expression assay
def: "A method which assesses transcript expression by reverse transcription of purified mRNA into the corresponding complementary DNA (cDNA) before insertion into a vector, allowing synthesis of a large number of copies of the sequence for analysis." [Mosby:Mosbys_Medical_Dictionary--8th_Ed, Segen:Segens_Medical_Dictionary_2012]
synonym: "cDNA" EXACT DISPLAY_SYNONYM []
xref: OBI:0600064
is_a: MMO:0000641 ! transcript expression assay
created_by: jrsmith
creation_date: 2018-05-28T18:07:22Z

[Term]
id: MMO:0000646
name: nucleic acid dot/slot blot assay
def: "A method that assesses transcript expression in which unfracionated RNA is covalently bound to a membrane and subsequently analysed by hybridization to one or more specific probes that have been labelled to allow detection, or DNA sequences of interest are bound to a membrane and hybridized to a labelled RNA/cDNA sample. Visualization of the sequence-specific binding of labelled molecules to target(s) gives an indication of the amount of the sequence of interest in the original sample." [https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/dot-blot "Website"]
synonym: "dot blot" EXACT DISPLAY_SYNONYM []
synonym: "RNA dot/slot blot assay" RELATED []
xref: ECO:0001040
xref: OBI:0002171
is_a: MMO:0000641 ! transcript expression assay
created_by: jrsmith
creation_date: 2018-05-28T18:08:59Z

[Term]
id: MMO:0000647
name: Northern blot assay
alt_id: MMO:0000339
def: "A method which assesses transcript expression in which RNA is size-fractionated by gel electrophoresis and transferred and covalently bound to a membrane. The RNA on the membrane is subsequently analysed by hybridization to one or more specific probes that have been labelled to allow detection. Visualization of the sequence-specific binding of labelled probe(s) to target RNAs gives an indication of the level and size of the target in the original sample." [PMID:21125485]
synonym: "northern" EXACT DISPLAY_SYNONYM []
synonym: "RNA blot" RELATED []
xref: OBI:0000860
is_a: MMO:0000100 ! gel electrophoresis
is_a: MMO:0000641 ! transcript expression assay
created_by: jrsmith
creation_date: 2018-05-28T18:11:40Z

[Term]
id: MMO:0000648
name: high throughput transcription profiling by array
def: "A method which assesses transcript expression by the use of an array, an ordered two dimensional collection of specific single-stranded DNA probes (either short oligonucleotides or longer DNA strands) which is hybridized to a labelled cDNA or RNA sample under high-stringency conditions. Detection of the labelled targets gives an indication of the presence and/or amount of that target in the original sample." [https://en.wikipedia.org/wiki/Microarray "Wikipedia"]
synonym: "transcript array" EXACT DISPLAY_SYNONYM []
xref: efo:EFO_0002768
xref: OBI:0001463
is_a: MMO:0000641 ! transcript expression assay
is_a: MMO:0000644 ! high throughput expression assay
created_by: jrsmith
creation_date: 2018-05-28T18:13:28Z

[Term]
id: MMO:0000649
name: high throughput transcription profiling by microarray
def: "A method which assesses transcript expression by the use of a microarray, an ordered two dimensional collection of specific single-stranded DNA probes (either short oligonucleotides or longer DNA strands) densely packed into a small area. The array is hybridized to a labelled cDNA or RNA sample under high-stringency conditions. Detection of the labelled targets gives an indication of the presence and/or amount of that target in the original sample." [https://en.wikipedia.org/wiki/Microarray "Wikipedia"]
synonym: "microarray" EXACT DISPLAY_SYNONYM []
synonym: "microarray assay" BROAD []
xref: ECO:0000058
is_a: MMO:0000648 ! high throughput transcription profiling by array
created_by: jrsmith
creation_date: 2018-05-28T18:18:07Z

[Term]
id: MMO:0000650
name: high throughput transcription profiling by tiling array
def: "A method which assesses expression transcripts from a specific, contiguous region of the genome by the use of a tiling microarray." [https://en.wikipedia.org/wiki/Tiling_array "Wikipedia"]
synonym: "tiling array" EXACT DISPLAY_SYNONYM []
synonym: "tiling array assay" EXACT []
xref: OBI:0001235
is_a: MMO:0000648 ! high throughput transcription profiling by array
created_by: jrsmith
creation_date: 2018-05-28T18:23:06Z

[Term]
id: MMO:0000651
name: nuclease protection assay
def: "A method in which single-stranded, discretely-sized antisense DNA or RNA probe(s) are hybridized in solution to a sample of RNA. Unhybridized probe and sample nucleotides are removed by digestion with one or more nucleases, enzymes which specifically cleave RNA, DNA or both. The remaining probe-target hybrids are analyzed, e.g. by electrophoresis and/or other detection methods." [https://en.wikipedia.org/wiki/Nuclease_protection_assay "Wikipedia", https://www.thermofisher.com/us/en/home/references/ambion-tech-support/ribonuclease-protection-assays/general-articles/the-basics-what-is-a-nuclease-protection-assay.html "Website"]
xref: ECO:0001106
is_a: MMO:0000641 ! transcript expression assay
created_by: jrsmith
creation_date: 2018-05-28T18:24:50Z

[Term]
id: MMO:0000652
name: ribonuclease protection assay
def: "A nuclease protection assay in which the probe is RNA and the nuclease is one or more ribonucleases which preferentially cleave single-stranded RNA." [https://en.wikipedia.org/wiki/Nuclease_protection_assay "Wikipedia", https://www.thermofisher.com/us/en/home/references/ambion-tech-support/ribonuclease-protection-assays/general-articles/the-basics-what-is-a-nuclease-protection-assay.html "Website"]
synonym: "RNA protection assay" RELATED []
synonym: "RNase protection" EXACT DISPLAY_SYNONYM []
synonym: "RNase protection" RELATED []
synonym: "RPA" RELATED []
xref: ECO:0000110
xref: OBI:0001670
is_a: MMO:0000651 ! nuclease protection assay
created_by: jrsmith
creation_date: 2018-05-28T18:26:55Z

[Term]
id: MMO:0000653
name: nuclease S1 protection assay
def: "A nuclease protection assay in which the probe is DNA and the nuclease is S1 nuclease, an endonuclease which preferentially cleaves single-stranded polynucleotides, including both ssDNA and ssRNA." []
synonym: "nuclease S1" EXACT DISPLAY_SYNONYM []
synonym: "S1 nuclease protection assay" EXACT []
xref: ECO:0005521
is_a: MMO:0000651 ! nuclease protection assay
created_by: jrsmith
creation_date: 2018-05-28T18:29:15Z

[Term]
id: MMO:0000654
name: primer extension assay
def: "A method which assesses transcript expression and structure by primer extension, that is, an assay in which an oligonucleotide primer is annealed to RNA and extended to a cDNA copy by reverse transcription. When the RNA of interest is present in the sample, the size of the product indicates the position of the 5' end of the RNA. In the presence of an excess of primer, the amount of the product is an indication of the level of target RNA in the sample." [https://www.nationaldiagnostics.com/electrophoresis/article/primer-extension "Website"]
synonym: "primer extension" EXACT DISPLAY_SYNONYM []
xref: ECO:0001819
xref: OBI:0002445
is_a: MMO:0000641 ! transcript expression assay
created_by: jrsmith
creation_date: 2018-05-28T18:31:00Z

[Term]
id: MMO:0000655
name: reverse transcription polymerase chain reaction assay
alt_id: MMO:0000461
def: "A method which assesses transcript expression by conversion of an RNA template into complementary DNA (cDNA) by reverse transcription. The cDNA is used as a template for exponential amplification by the polymerase chain reaction, a technique which produces a large number of copies of one or more specific DNA sequences via multiple rounds of thermal cycling where DNA is melted, annealed to oligonucleotide primers, and extended using a thermostable DNA polymerase." [https://en.wikipedia.org/wiki/Polymerase_chain_reaction "Wikipedia", https://en.wikipedia.org/wiki/Reverse_transcription_polymerase_chain_reaction "Wikipedia"]
synonym: "reverse transcription polymerase chain reaction" EXACT []
synonym: "RT-PCR" RELATED []
synonym: "RT-PCR" EXACT DISPLAY_SYNONYM []
xref: ECO:0000109
xref: efo:EFO_0002943
xref: OBI:0001170
xref: OBI:0001361
is_a: MMO:0000459 ! polymerase chain reaction assay
created_by: jrsmith
creation_date: 2018-05-28T18:32:25Z

[Term]
id: MMO:0000656
name: quantitative reverse transcription polymerase chain reaction assay
alt_id: MMO:0000462
def: "A method in which amplification of a specific RNA/cDNA sequence by a reverse transcription polymerase chain reaction is monitored by detection of fluorescent probes or intercalating dyes that indicate the (absolute or relative) amount of product being produced in real time." [https://en.wikipedia.org/wiki/Real-time_polymerase_chain_reaction "Wikipedia"]
synonym: "qRT-PCR" RELATED []
synonym: "quantitative reverse transcription polymerase chain reaction" EXACT []
synonym: "quantitative RT-PCR" RELATED []
synonym: "real-time RT-PCR" RELATED []
synonym: "RT-qPCR" RELATED []
xref: ECO:0000231
xref: OBI:0000911
is_a: MMO:0000460 ! real-time polymerase chain reaction assay
is_a: MMO:0000655 ! reverse transcription polymerase chain reaction assay
created_by: jrsmith
creation_date: 2018-05-28T18:35:12Z

[Term]
id: MMO:0000657
name: in situ reverse transcription polymerase chain reaction assay
def: "A method in which reverse transcription polymerase chain reaction is performed directly on tissue sections to assess transcript expression." [PMID:21922403]
synonym: "in situ RT-PCR" EXACT DISPLAY_SYNONYM []
synonym: "in situ RT-PCR" RELATED []
is_a: MMO:0000643 ! in situ expression assay
is_a: MMO:0000655 ! reverse transcription polymerase chain reaction assay
created_by: jrsmith
creation_date: 2018-05-28T18:37:46Z

[Term]
id: MMO:0000658
name: ribonucleic acid in situ hybridization assay
def: "A method in which RNA or oligonucleotide probes are hybridized to tissue sections, cells, whole mounts, or circulating tumor cells to assess the levels and/or localization of specific RNAs." [https://en.wikipedia.org/wiki/In_situ_hybridization "Wikipedia"]
synonym: "RNA in situ" EXACT DISPLAY_SYNONYM []
synonym: "RNA in situ hybridization assay" RELATED []
synonym: "RNA-ISH" RELATED []
xref: OBI:0001686
is_a: MMO:0000641 ! transcript expression assay
is_a: MMO:0000643 ! in situ expression assay
created_by: jrsmith
creation_date: 2018-05-28T18:39:22Z

[Term]
id: MMO:0000659
name: RNA-seq assay
def: "A method which assesses transcript expression and structure via high-throughput sequencing. Sample RNA is purified, fragmented, reverse transcribed to cDNA with the addition of sequencing primers, sequenced and analyzed." [https://rnaseq.uoregon.edu/ "RNA-seqlopedia"]
synonym: "ribonucleic acid sequencing assay" EXACT []
synonym: "RNA-seq" EXACT []
synonym: "transcription profiling by high throughput sequencing" RELATED []
synonym: "whole transcriptome sequencing" RELATED []
xref: ECO:0000295
xref: efo:EFO_0002770
xref: efo:EFO_0008896
xref: OBI:0001271
is_a: MMO:0000641 ! transcript expression assay
is_a: MMO:0000644 ! high throughput expression assay
created_by: jrsmith
creation_date: 2018-05-28T18:42:29Z

[Term]
id: MMO:0000660
name: serial analysis of gene expression assay
def: "A method which assesses transcript expression by producing short (~11 nt) sequence tags from an RNA sample, binding them into ditags for PCR amplification, splitting the PCR products into singlets, and concatenating these together, followed by cloning and sequencing the concatemers to quantify the recurrence of individual tags.  The tag counts give an indication of the relative expression of the corresponding genes/RNAs." [https://en.wikipedia.org/wiki/Serial_analysis_of_gene_expression "Wikipedia"]
synonym: "SAGE" EXACT DISPLAY_SYNONYM []
synonym: "SAGE" RELATED []
xref: efo:EFO_0002941
xref: OBI:0002029
is_a: MMO:0000641 ! transcript expression assay
is_a: MMO:0000644 ! high throughput expression assay
created_by: jrsmith
creation_date: 2018-05-28T18:45:18Z

[Term]
id: MMO:0000661
name: protein function-based expression assay
def: "Any method which measures the levels, timing, and/or location of, or differentially quantifies, proteins through the use of assays to measure specific protein function." []
synonym: "gene product function" RELATED []
synonym: "protein function" EXACT DISPLAY_SYNONYM []
is_a: MMO:0000642 ! protein expression assay
created_by: jrsmith
creation_date: 2018-05-28T18:46:49Z

[Term]
id: MMO:0000662
name: immunofluorescence
def: "The labeling of antibodies or antigens with fluorescent dyes especially for the purpose of demonstrating the presence of a particular antigen or antibody in a tissue preparation, smear, or other biological sample." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, https://www.sinobiological.com/category/principle-of-if "Wikipedia"]
synonym: "immunofluorescence" EXACT DISPLAY_SYNONYM []
synonym: "immunofluorescence assay" EXACT []
xref: ECO:0000007
is_a: MMO:0000498 ! immunohistochemistry
created_by: jrsmith
creation_date: 2018-05-28T18:51:30Z

[Term]
id: MMO:0000663
name: immunoelectron microscopy
def: "An assay using electron microscopy to determine the amount, structure and/or localization of specific proteins in cells or tissues by staining with antibodies that have been conjugated with an electron-dense label such as gold." [https://www.proteinatlas.org/learn/method/immunoelectron+microscopy "Website"]
synonym: "immuno EM" EXACT DISPLAY_SYNONYM []
xref: ECO:0006070
is_a: MMO:0000110 ! ex vivo electron microscopy
is_a: MMO:0000498 ! immunohistochemistry
created_by: jrsmith
creation_date: 2018-05-28T18:53:10Z

[Term]
id: MMO:0000664
name: high throughput proteomic profiling
def: "Any method which uses rapid, highly parallel techniques to identify and characterize, for example determine the levels of, a large number of proteins in a limited number of samples, a limited number of proteins in a large number of samples, or a large number of proteins in a large number of samples." [https://en.wikipedia.org/wiki/High_throughput_biology "Wikipedia", https://en.wikipedia.org/wiki/Proteomics#High-throughput_proteomic_technologies "Wikipedia"]
synonym: "proteomic profiling" EXACT DISPLAY_SYNONYM []
is_a: MMO:0000642 ! protein expression assay
is_a: MMO:0000644 ! high throughput expression assay
created_by: jrsmith
creation_date: 2018-05-28T18:57:02Z

[Term]
id: MMO:0000665
name: high throughput proteomic profiling by mass spectrometry
def: "The use of mass spectrometry as a rapid, highly parallel techniques to identify and characterize, for example determine the levels of, a large number of proteins in a limited number of samples, a limited number of proteins in a large number of samples, or a large number of proteins in a large number of samples." [https://en.wikipedia.org/wiki/High_throughput_biology "Wikipedia", https://en.wikipedia.org/wiki/Proteomics "Wikipedia"]
xref: ECO:0001119
xref: ECO:0005585
xref: ECO:0005603
is_a: MMO:0000534 ! mass spectrometry
is_a: MMO:0000664 ! high throughput proteomic profiling
created_by: jrsmith
creation_date: 2018-05-28T19:00:36Z

[Term]
id: MMO:0000666
name: high throughput proteomic profiling by array
def: "Any method which employs an array (a two-dimensionally ordered arrangement of tissues, antibodies or other biomolecular interactors on a solid substrate) to identify and characterize, for example determine the levels of, a large number of proteins in a limited number of samples, a limited number of proteins in a large number of samples, or a large number of proteins in a large number of samples." [https://en.wikipedia.org/wiki/Protein_microarray "Wikipedia"]
xref: OBI:0001318
is_a: MMO:0000664 ! high throughput proteomic profiling
created_by: jrsmith
creation_date: 2018-05-28T19:02:46Z

[Term]
id: MMO:0000667
name: high throughput proteomic profiling by tissue array
def: "A method which employs a two-dimensionally ordered arrangement of tissues in paraffin blocks to histologically characterize protein expression in those tissues." [https://en.wikipedia.org/wiki/Tissue_microarray "Wikipedia", https://medicine.yale.edu/pathology/ypts/tissuemicroarrayfacility/index.aspx "Website"]
is_a: MMO:0000666 ! high throughput proteomic profiling by array
created_by: jrsmith
creation_date: 2018-05-28T19:04:55Z

[Term]
id: MMO:0000668
name: high throughput proteomic profiling by antibody array
def: "A method which employs a two-dimensionally ordered arrangement of antibodies spotted on a solid substrate for the detection and quantification of their target antigens in one or more samples." [https://en.wikipedia.org/wiki/Antibody_microarray "Wikipedia"]
is_a: MMO:0000666 ! high throughput proteomic profiling by array
created_by: jrsmith
creation_date: 2018-05-28T19:06:24Z

[Term]
id: MMO:0000669
name: western blot assay
alt_id: MMO:0000338
def: "An assay in which one or more protein samples are size-, structure-, and/or charge-separated by one- or two-dimensional gel electrophoresis, transferred to a membrane and an immunostaining procedure is used to detect and quantify one or more specific proteins in the sample(s)." [Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed, https://en.wikipedia.org/wiki/Western_blot "Wikipedia", ISBN:978-1416049982]
synonym: "protein immunoblot assay" RELATED []
synonym: "western" EXACT DISPLAY_SYNONYM []
xref: ECO:0000112
xref: OBI:0000854
is_a: MMO:0000100 ! gel electrophoresis
is_a: MMO:0000642 ! protein expression assay
created_by: jrsmith
creation_date: 2018-05-28T19:07:56Z

[Term]
id: MMO:0000670
name: in situ reporter assay
def: "An assay designed to detect expression of a reporter gene in intact tissues or cells. A reporter gene is a gene whose product is not ordinarily present in the assayed organism or cell type, such as beta-galactosidase (beta-gal) or green fluorescent protein (GFP)." [Alliance:Alliance_Expression_Working_Group]
synonym: "in situ reporter" EXACT DISPLAY_SYNONYM []
xref: ECO:0000049
is_a: MMO:0000643 ! in situ expression assay
created_by: jrsmith
creation_date: 2018-05-28T19:11:19Z

[Term]
id: MMO:0000671
name: transgenic in situ reporter assay
def: "An in situ reporter assay designed to detect, in intact cells or tissues, expression of a reporter gene that has been randomly integrated into the genome.  A reporter gene is a gene whose product is not ordinarily present in the assayed organism or cell type, such as beta-galactosidase (beta-gal) or green fluorescent protein (GFP)." [Alliance:Alliance_Expression_Working_Group]
synonym: "transgenic reporter" EXACT DISPLAY_SYNONYM []
is_a: MMO:0000670 ! in situ reporter assay
created_by: jrsmith
creation_date: 2018-05-28T19:12:52Z

[Term]
id: MMO:0000672
name: knock-in in situ reporter assay
def: "An in situ reporter assay designed to detect, in intact cells or tissues, expression of a reporter gene that has been inserted into the genome by the process of homologous recombination with the goal of recapitulating the expression pattern of the endogenous gene. A reporter gene is a gene whose product is not ordinarily present in the assayed organism or cell type, such as beta-galactosidase (beta-gal) or green fluorescent protein (GFP)." [Alliance:Alliance_Expression_Working_Group]
synonym: "knock-in reporter" EXACT DISPLAY_SYNONYM []
xref: efo:EFO_0000561
is_a: MMO:0000670 ! in situ reporter assay
created_by: jrsmith
creation_date: 2018-05-28T19:18:01Z

[Term]
id: MMO:0000673
name: in situ recombinase reporter assay
def: "An in situ reporter assay that uses intact cells or tissues from an organism with a recombinase-carrying allele and a reporter gene-carrying allele to detect the cells and/or tissues where the recombinase has been active. The reporter gene will only be expressed when the recombinase has removed/rearranged part of its sequence.  Cre is an example of a commonly used recombinase." [Alliance:Alliance_Expression_Working_Group]
synonym: "recombinase reporter" EXACT DISPLAY_SYNONYM []
is_a: MMO:0000670 ! in situ reporter assay
created_by: jrsmith
creation_date: 2018-05-28T19:19:25Z

[Term]
id: MMO:0000674
name: isolated tissue free fatty acid measurement test
synonym: "isolated tissue NEFA measurement test" EXACT []
synonym: "isolated tissue non-esterified fatty acid measurement test" EXACT []
is_a: MMO:0000526 ! isolated tissue lipid analysis
created_by: sjwang
creation_date: 2018-11-26T14:39:50Z

[Term]
id: MMO:0000675
name: vapor pressure osmometry
def: "Technique for the determination of a polymer's number average molecular weight. It works by taking advantage of the decrease in vapor pressure that occurs when solutes are added to pure solvent." [https://en.wikipedia.org/wiki/Vapor_pressure_osmometry "Wikipedia"]
is_a: MMO:0000170 ! osmometry
created_by: sjwang
creation_date: 2018-12-06T16:09:18Z

[Term]
id: MMO:0000676
name: urine urea analysis
def: "Any assay which measures the amount, level or concentration of urea in urine." []
is_a: MMO:0000147 ! urine analysis
created_by: sjwang
creation_date: 2018-12-07T15:26:55Z

[Term]
id: MMO:0000677
name: blood NAGA activity assay
def: "A method which quantifies the catalytic effect exerted by α-N-acetylgalactosaminidase in a specified sample of blood." []
synonym: "blood α-N-acetylgalactosaminidase activity assay" EXACT []
is_a: MMO:0000429 ! blood enzyme activity assay
created_by: sjwang
creation_date: 2018-12-07T15:31:16Z

[Term]
id: MMO:0000678
name: anion-exchange chromatography
def: "A type of chromatography where a positively charged ion exchange resin with an affinity for molecules having net negative surface charges is used to separate the molecules." [ECO:0001010]
is_a: MMO:0000404 ! liquid column chromatography
created_by: sjwang
creation_date: 2018-12-20T10:12:36Z

[Term]
id: MMO:0000679
name: cell fractionation
def: "A type of fractionation where sub-cellular components are separated based on their physical properties such as density in a sucrose density gradient." [ECO:0000004]
is_a: MMO:0000222 ! isolated cell method
created_by: sjwang
creation_date: 2018-12-20T10:15:21Z

[Term]
id: MMO:0000680
name: chromatin immunoprecipitation
def: "A type of chromatin immunoprecipitation that uses a tiling microarray for the detection of protein-bound DNA regions where chromatin is immunoprecipitated for protein tagging and DNA is sheared from the cross-linked protein-DNA complex to be arrayed revealing the protein-bound genomic regions." [ECO:0000230]
synonym: "ChIP-chip" RELATED []
synonym: "ChIP-on-chip" RELATED []
is_a: MMO:0000682 ! immunoprecipitation
created_by: sjwang
creation_date: 2018-12-20T10:18:35Z

[Term]
id: MMO:0000681
name: co-fractionation
def: "A type of fractionation evidence resulting from a protein fractionated with other compounds, factors, or macromolecules." [ECO:0000102]
is_obsolete: true
created_by: sjwang
creation_date: 2018-12-20T10:33:46Z

[Term]
id: MMO:0000682
name: immunoprecipitation
def: "A type of protein assay that involves precipitation of a multivalent antigen by a bivalent antibody for protein isolation." [ECO:0000085]
is_a: MMO:0000286 ! molecular separation method
created_by: sjwang
creation_date: 2018-12-20T10:38:08Z

[Term]
id: MMO:0000683
name: co-immunoprecipitation
def: "A type of immunoprecipitation that involves precipitating two or more proteins via binding to an antibody specific to a single protein, followed by protein identification." [ECO:0000070]
is_a: MMO:0000682 ! immunoprecipitation
created_by: sjwang
creation_date: 2018-12-20T10:44:57Z

[Term]
id: MMO:0000684
name: gel filtration chromatography
def: "A type of chromatography resulting from the exclusion of proteins based on molecular size by filtration through a porous matrix (swollen gel), from which larger molecules are excluded." [ECO:0001049]
is_a: MMO:0000404 ! liquid column chromatography
created_by: sjwang
creation_date: 2018-12-20T10:47:33Z

[Term]
id: MMO:0000685
name: confocal microscopy
def: "A type of fluorescence microscopy where sharp images are taken by excluding most of the light from the specimen that is not from the microscope's focal plane, thus allowing better contrast and less haze, which makes it possible to build three-dimensional reconstructions of a volume of the specimen by assembling a series of thin slices taken along the vertical axis." [ECO:0005587, https://ibidi.com/content/216-confocal-microscopy]
synonym: "CLSM" NARROW []
synonym: "confocal laser scanning microscopy" NARROW []
synonym: "laser confocal scanning microscopy" NARROW []
synonym: "LCSM" NARROW []
is_a: MMO:0000111 ! ex vivo light microscopy
is_a: MMO:0000415 ! in vivo light microscopy
created_by: sjwang
creation_date: 2018-12-20T10:50:58Z

[Term]
id: MMO:0000686
name: immunofluorescence confocal microscopy
def: "This technique incorporates use of confocal microscopy and immunohistochemistry to produce magnified images. Immunohistochemistry is the microscopic localization of specific antigens in tissues by staining with antibodies labeled with fluorescent or pigmented material." [ECO:0005600, https://ibidi.com/content/216-confocal-microscopy, PMID:1447959]
xref: PMID:1447959
is_a: MMO:0000662 ! immunofluorescence
is_a: MMO:0000685 ! confocal microscopy
created_by: sjwang
creation_date: 2018-12-20T10:54:33Z

[Term]
id: MMO:0000687
name: urine aldosterone analysis
def: "Any test which measures the amount of aldosterone, a mineralocorticoid hormone produced by the adrenal cortex, in urine." []
is_a: MMO:0000147 ! urine analysis
created_by: sjwang
creation_date: 2018-12-20T15:19:50Z

[Term]
id: MMO:0000688
name: blood parathyroid hormone analysis
def: "Any method by which the level or concentration in a sample of blood of parathyroid hormone is measured." []
is_a: MMO:0000311 ! blood hormone analysis
created_by: sjwang
creation_date: 2018-12-27T10:08:44Z

[Term]
id: MMO:0000689
name: plasma parathyroid hormone analysis
def: "Any method by which the level or concentration in a sample of plasma of parathyroid hormone is measured." []
is_a: MMO:0000688 ! blood parathyroid hormone analysis
created_by: sjwang
creation_date: 2018-12-27T10:11:49Z

[Term]
id: MMO:0000690
name: serum parathyroid hormone analysis
def: "Any method by which the level or concentration in a sample of serum of parathyroid hormone is measured." []
is_a: MMO:0000688 ! blood parathyroid hormone analysis
created_by: sjwang
creation_date: 2018-12-27T10:13:01Z

[Term]
id: MMO:0000691
name: automated plasma total cholesterol analysis
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure total cholesterol in plasma." []
is_a: MMO:0000284 ! plasma total cholesterol measurement test
is_a: MMO:0000553 ! automated plasma analysis
created_by: sjwang
creation_date: 2019-01-02T14:23:40Z

[Term]
id: MMO:0000692
name: automated chemiluminescent-based plasma total cholesterol analysis
is_a: MMO:0000691 ! automated plasma total cholesterol analysis
created_by: sjwang
creation_date: 2019-01-02T14:26:58Z

[Term]
id: MMO:0000693
name: automated plasma low-density lipoprotein-cholesterol analysis
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure low-density lipoprotein-cholesterol in plasma." []
is_a: MMO:0000283 ! plasma low-density lipoprotein-cholesterol measurement test
is_a: MMO:0000553 ! automated plasma analysis
created_by: sjwang
creation_date: 2019-01-02T14:30:00Z

[Term]
id: MMO:0000694
name: automated chemiluminescent-based plasma low-density lipoprotein-cholesterol analysis
is_a: MMO:0000693 ! automated plasma low-density lipoprotein-cholesterol analysis
created_by: sjwang
creation_date: 2019-01-02T14:33:45Z

[Term]
id: MMO:0000695
name: optical coherence tomography
def: "Optical coherence tomography (OCT) is an imaging technique that uses low-coherence light to capture micrometer-resolution, two- and three-dimensional images from within optical scattering media (e.g., biological tissue)." [PMID:3411196]
is_obsolete: true
created_by: sjwang
creation_date: 2019-03-19T16:51:24Z

[Term]
id: MMO:0000696
name: optical coherence tomography
def: "Optical coherence tomography (OCT) is an imaging technique that uses low-coherence light to capture micrometer-resolution, two- and three-dimensional images from within optical scattering media (e.g., biological tissue)." [https://en.wikipedia.org/wiki/Optical_coherence_tomography "Wikipedia"]
is_a: MMO:0000026 ! in vivo method
created_by: sjwang
creation_date: 2019-03-19T16:52:11Z

[Term]
id: MMO:0000697
name: metabolic cage water drinking measurement method
def: "This is a method which utilizes a metabolic cage, a housing unit constructed for the separate collection of liquid and solid waste, to determine the amount of water consumed during a fixed time period." [https://meshb.nlm.nih.gov/record/ui?ui=D009543 "MESH"]
is_a: MMO:0000860 ! metabolic cage drink measurement method (MMO:0000697)
created_by: slaulede
creation_date: 2019-12-16T17:19:17Z

[Term]
id: MMO:0000698
name: comprehensive metabolic panel
def: "The comprehensive metabolic panel (CMP) is a panel of 14 blood tests which serves as an initial broad medical screening tool. The CMP provides a rough check of kidney function, liver function, diabetic and parathyroid status, and electrolyte and fluid balance." [https://en.wikipedia.org/wiki/Comprehensive_metabolic_panel "Wikipedia"]
synonym: "basic metabolic panel" RELATED []
synonym: "BMP" RELATED []
synonym: "chemical screen" EXACT []
is_a: MMO:0000030 ! ex vivo blood analysis
created_by: slaulede
creation_date: 2019-12-19T16:55:08Z

[Term]
id: MMO:0000699
name: serum hormone analysis
def: "A method to measure one or more hormones in serum. A hormone is a chemical substance which is produced in one part or organ of the body and initiates or regulates the activity of an organ or a group of cells in another part of the body." []
is_a: MMO:0000311 ! blood hormone analysis
created_by: sjwang
creation_date: 2020-01-28T10:29:43Z

[Term]
id: MMO:0000700
name: plasma hormone analysis
def: "A method to measure one or more hormones in plasma. A hormone is a chemical substance which is produced in one part or organ of the body and initiates or regulates the activity of an organ or a group of cells in another part of the body." []
is_a: MMO:0000311 ! blood hormone analysis
created_by: sjwang
creation_date: 2020-01-28T10:32:46Z

[Term]
id: MMO:0000701
name: blood eicosanoid analysis
def: "A method to determine the level of one or more eicosanoids, physiologically active molecules derived by oxidation of twenty-carbon essential fatty acids such as arachidonic acid, in whole blood." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed]
synonym: "blood icosanoid analysis" EXACT []
is_a: MMO:0000038 ! blood lipid analysis
created_by: slaulede
creation_date: 2020-05-05T08:58:08Z

[Term]
id: MMO:0000702
name: plasma eicosanoid analysis
def: "A method to determine the level of one or more eicosanoids, physiologically active molecules derived by oxidation of twenty-carbon essential fatty acids such as arachidonic acid, in plasma. Plasma is the fluid portion of the blood in which the particulate components are suspended, or from which the particulate components have been removed by centrifugation or settling without clotting." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed]
synonym: "plasma icosanoid analysis" EXACT []
is_a: MMO:0000701 ! blood eicosanoid analysis
created_by: slaulede
creation_date: 2020-05-05T10:52:21Z

[Term]
id: MMO:0000703
name: serum eicosanoid analysis
def: "A method to determine the level of one or more eicosanoids, physiologically active molecules derived by oxidation of twenty-carbon essential fatty acids such as arachidonic acid, inserum. Serum is the clear liquid that separates from blood when it is allowed to clot completely, and is therefore blood plasma from which protein factors have been removed during clotting." [American_Heritage:The_American_Heritage_Medical_Dictionary_2007, Dorland:Dorlands_Illustrated_Medical_Dictionary--31st_Ed]
synonym: "serum icosanoid analysis" EXACT []
is_a: MMO:0000701 ! blood eicosanoid analysis
created_by: slaulede
creation_date: 2020-05-05T11:54:27Z

[Term]
id: MMO:0000704
name: photometry
def: "The measurement of transmittance (a linear scale from 0-100%) or absorbance (a logarithmic scale from zero to infinity) of particular wavelengths of light by the use of filters. Concentration values of solutes are calculated from measured values." [https://support.hach.com/app/answers/answer_view/a_id/1000891/~/what-is-the-difference-between-a-colorimeter-and-a-spectrophotometer%3F- "Hach", https://www.instrumart.com/MoreAboutCategory?CategoryID=6140 "Instrumart"]
synonym: "filter colorimetry" EXACT []
is_a: MMO:0000172 ! spectrometry
created_by: slaulede
creation_date: 2020-05-05T16:32:46Z

[Term]
id: MMO:0000705
name: blood carbohydrates and carbohydrate derivative analysis
def: "A method to determine the level of one or more carbohydrates or carbohydrate derivatives, any of a large group of organic compounds occurring in foods and living tissues and including sugars, starch, and cellulose, in blood." [https://www.lexico.com/en/definition/carbohydrate "Lexico"]
xref: CHEBI:78616
is_a: MMO:0000030 ! ex vivo blood analysis
created_by: slaulede
creation_date: 2020-05-07T12:34:45Z

[Term]
id: MMO:0000706
name: blood fructosamine analysis
def: "A method to determine the level of fructosamine, the compound that results from glycation reactions between a sugar and a primary amine, or isoglucosamine, found in a specific volume of blood." [CMO:0002855]
synonym: "blood D-Isoglucosamine analysis" EXACT []
xref: CMO:0002855
is_a: MMO:0000705 ! blood carbohydrates and carbohydrate derivative analysis
created_by: slaulede
creation_date: 2020-05-07T12:58:54Z

[Term]
id: MMO:0000707
name: plasma fructosamine analysis
def: "A method to determine the level of fructosamine, the compound that results from glycation reactions between a sugar and a primary amine, or isoglucosamine, found in a specific volume of plasma." [CMO:0002855]
synonym: "plasma D-Isoglucosamine analysis" EXACT []
xref: CMO:0002855
is_a: MMO:0000706 ! blood fructosamine analysis
created_by: slaulede
creation_date: 2020-05-07T13:04:08Z

[Term]
id: MMO:0000708
name: serum fructosamine analysis
def: "A method to determine the level of fructosamine, the compound that results from glycation reactions between a sugar and a primary amine, or isoglucosamine, found in a specific volume of plasma." [CMO:0002855]
synonym: "serum D-Isoglucosamine analysis" EXACT []
xref: CMO:0002855
is_a: MMO:0000706 ! blood fructosamine analysis
created_by: slaulede
creation_date: 2020-05-07T13:07:02Z

[Term]
id: MMO:0000709
name: nuclear magnetic resonance spectroscopy
def: "Nuclear Magnetic Resonance (NMR) spectroscopy is a technique to observe local magnetic fields around atomic nuclei. The sample is placed in a magnetic field and the NMR signal is produced by excitation of the nuclei sample with radio waves into nuclear magnetic resonance, which is detected with sensitive radio receivers." [https://en.wikipedia.org/wiki/Nuclear_magnetic_resonance_spectroscopy "Wikipedia"]
synonym: "magnetic resonance spectroscopy" EXACT []
synonym: "MRS" EXACT []
synonym: "NMR spectroscopy" EXACT []
is_a: MMO:0000026 ! in vivo method
is_a: MMO:0000027 ! ex vivo method
created_by: slaulede
creation_date: 2020-05-22T10:48:21Z

[Term]
id: MMO:0000710
name: electron paramagnetic resonance spectroscopy
def: "A method for studying materials with unpaired electrons. The basic concepts of EPR are analogous to those of nuclear magnetic resonance (NMR), but it is electron spins that are excited instead of the spins of atomic nuclei." [https://en.wikipedia.org/wiki/Electron_paramagnetic_resonance "Wikipedia"]
synonym: "electron spin resonance spectroscopy" EXACT []
synonym: "EPR spectroscopy" EXACT []
synonym: "ESR spectroscopy" EXACT []
is_a: MMO:0000026 ! in vivo method
is_a: MMO:0000027 ! ex vivo method
created_by: slaulede
creation_date: 2020-05-22T11:14:53Z

[Term]
id: MMO:0000711
name: electron paramagnetic resonance oximetry
def: "A minimally invasive magnetic resonance method capable of measuring direct and absolute values of pO2 or O2 concentration." [PMID:20218670]
synonym: "EPR oximetry" EXACT []
is_a: MMO:0000710 ! electron paramagnetic resonance spectroscopy
created_by: slaulede
creation_date: 2020-05-22T11:34:01Z

[Term]
id: MMO:0000712
name: centrifugation
def: "A technique that involves the application of centrifugal force to separate particles from a solution, biological molecules, cells, or organelles according to their size, shape, density, viscosity of the medium and rotor speed." [https://en.wikipedia.org/wiki/Centrifugation "Wikipedia"]
is_a: MMO:0000161 ! isolated tissue method
is_a: MMO:0000286 ! molecular separation method
is_a: MMO:0000679 ! cell fractionation
created_by: slaulede
creation_date: 2020-05-22T15:44:33Z

[Term]
id: MMO:0000713
name: enzyme immunoassay
def: "Enzyme immunoassays (EIAs) use antibodies to detect the presence of antigens in solution in microtiter plates or in vivo. There are many different types of EIAs, but they all involve an antibody molecule whose constant region binds an enzyme, leaving the variable region free to bind its specific antigen." [https://bio.libretexts.org/Bookshelves/Microbiology/Book%3A_Microbiology_(OpenStax)/20%3A_Laboratory_Analysis_of_the_Immune_Response/20.4%3A_Enzyme_Immunoassays_(EIA)_and_Enzyme-Linked_Immunosorbent_Assays_(ELISA) "Biology_LibreTexts"]
synonym: "EIA" EXACT []
is_a: MMO:0000098 ! immunoassay
is_a: MMO:0000388 ! enzymatic method
created_by: slaulede
creation_date: 2020-05-26T17:34:31Z

[Term]
id: MMO:0000714
name: microplate reader
def: "Instruments which are used to detect biological, chemical or physical events of samples in microtiter plates. Common detection modes for microplate assays are absorbance, fluorescence intensity, luminescence, time-resolved fluorescence, and fluorescence polarization." [https://en.wikipedia.org/wiki/Plate_reader "Wikipedia"]
synonym: "microplate photometer" EXACT []
synonym: "plate reader" EXACT []
is_a: MMO:0000329 ! liquid phase colorimetry
is_a: MMO:0000704 ! photometry
created_by: slaulede
creation_date: 2020-06-05T13:10:50Z

[Term]
id: MMO:0000715
name: Morgan-Elson assay
def: "The Morgan-Elson assay is a colorimetric method for the determination of glucosamine and chondrosamine and may be used for determination of hyaluronidase activity." [PMID:14596836, PMID:16745305]
is_a: MMO:0000444 ! enzyme or transport activity assay
created_by: slaulede
creation_date: 2020-06-05T17:43:17Z

[Term]
id: MMO:0000716
name: fluorimetric Morgan-Elson assay for hyaluronidase activity
def: "A fluorimetric version of the Morgan-Elson assay for determination of hyaluronidase activity in biological samples. The readout involves a fluorescence spectrophotometer with excitation at 545 nm and emission at 604 nm." [PMID:14596836]
is_a: MMO:0000247 ! fluorometry
is_a: MMO:0000715 ! Morgan-Elson assay
created_by: slaulede
creation_date: 2020-06-05T18:00:42Z

[Term]
id: MMO:0000717
name: colorimetric Morgan-Elson assay for hyaluronidase activity
def: "A colorimetric version of the Morgan-Elson assay for determination of hyaluronidase activity in biological samples. The readout involves a spectrophotometer reading absorbance at 585 nm." [PMID:14596836]
is_a: MMO:0000327 ! colorimetry
is_a: MMO:0000715 ! Morgan-Elson assay
created_by: slaulede
creation_date: 2020-06-05T18:04:27Z

[Term]
id: MMO:0000718
name: Dynamic Contrast-Enhanced Magnetic Resonance Imaging
def: "Magnetic resonance imaging (MRI) contrast agents increase the contrast difference between normal and abnormal tissues. MRI with contrast can be used to follow the progress and/or treatment of diseases such as cancer, atherosclerosis, and renal disease." [https://www.sciencedirect.com/topics/medicine-and-dentistry/dynamic-contrast-enhanced-mri "ScienceDirect", PMID:27666161]
synonym: "DCE-MRI" EXACT []
is_a: MMO:0000019 ! magnetic resonance imaging
created_by: slaulede
creation_date: 2020-06-08T13:58:17Z

[Term]
id: MMO:0000719
name: freezing point osmometry
def: "An osmometer can determine the concentration of solutes in a solvent, based on the lowering of a solution's freezing point by increasing solute concentrations. The freezing point depression method of osmometry is the most commonly used method to measure the osmolality of aqueous samples." [https://www.aicompanies.com/osmometers/?utm_medium=adwords]
is_a: MMO:0000170 ! osmometry
created_by: slaulede
creation_date: 2020-06-12T16:09:10Z

[Term]
id: MMO:0000720
name: ultra-performance liquid chromatography
def: "An ultra-high pressure form of liquid column chromatography in which the solvent is forced through the column under high pressures of up to 1000 atmospheres (15,000 psi). Higher pressure and smaller column particle sizes of less than 2 um helps UPLC outperform HPLC." [https://www.pharmaguideline.com/2018/04/differences-between-hplc-and-uplc.html#gsc.tab=0]
synonym: "UHPLC" NARROW []
synonym: "ultra high performance liquid chromatography" NARROW []
synonym: "UPLC" NARROW []
is_a: MMO:0000404 ! liquid column chromatography
created_by: slaulede
creation_date: 2020-06-16T17:08:57Z

[Term]
id: MMO:0000721
name: ultra-performance liquid chromatography-mass spectrometry
def: "An analytical technique that combines the physical separation capabilities of ultra-pressure liquid chromatography (UPLC) with the mass analysis capabilities of mass spectrometry (MS). Molecular mixtures are initially separated into components by UPLC. As these components exit the column, they are subjected to mass spectrometry for identification based on their mass-to-charge ratio and behavior in a magnetic field." [https://www.waters.com/waters/en_US/Mass-Spec-Users-Prefer-UPLC/nav.htm?cid=10007802&locale=en_US]
synonym: "Ultra Performance Liquid Chromatography/Mass Spectrometry" EXACT []
synonym: "UPLC/MS" EXACT []
synonym: "uplc-mass spec" EXACT []
synonym: "uplc-ms" EXACT []
is_a: MMO:0000534 ! mass spectrometry
is_a: MMO:0000720 ! ultra-performance liquid chromatography
created_by: slaulede
creation_date: 2020-06-16T17:39:24Z

[Term]
id: MMO:0000722
name: ex vivo light microscopy with inverted microscope
def: "Microscopy with its light source from above pointing down, while the objectives and turret are below the stage pointing up - uses include micromanipulation applications where space above the specimen is required for manipulator mechanisms and the microtools they hold." [https://en.wikipedia.org/wiki/Inverted_microscope "Wikipedia"]
is_a: MMO:0000111 ! ex vivo light microscopy
created_by: slaulede
creation_date: 2020-06-25T13:41:29Z

[Term]
id: MMO:0000723
name: blood NAG activity assay
def: "A method which quantifies the catalytic effect exerted by N-acetyl-β-d-glucosaminidase in a specified sample of blood." []
synonym: "blood N-acetyl-β-d-glucosaminidase activity assay" EXACT []
is_a: MMO:0000429 ! blood enzyme activity assay
created_by: slaulede
creation_date: 2020-06-30T13:44:52Z

[Term]
id: MMO:0000725
name: passive avoidance test using a two-way shuttle box apparatus
def: "Passive avoidance describes experiments in which the animal learns to avoid an aversive event by suppressing a particular behavior. To learn to do so, the aversive stimulus must be clearly associated with the active behavioral component. The passive avoidance task is be carried out in a shuttle box with a light chamber and a dark chamber separated by a doorway (the step-through version of the task). Given that illuminated environments are unpleasant to rodents, when placed in the light chamber, they are led into the preferred dark compartment by its innate photophobia. During habituation, they’re allowed to do so, but in the conditioning phase of the passive avoidance test, the animal will receive a foot shock when he crosses to the dark chamber. His innate behavior of seeking a darker environment will thereby become associated with an aversive stimulus. When placed again in the light chamber, the animal will avoid entering the dark, shock-associated chamber." [https://conductscience.com/maze/portfolio/active-passive-avoidance-shuttle-box/ "Website"]
is_a: MMO:0000301 ! two way shuttlebox apparatus method
created_by: slaulede
creation_date: 2020-07-07T15:36:49Z

[Term]
id: MMO:0000726
name: blood p-phenylenediamine oxidase activity assay
def: "A method which quantifies the catalytic effect exerted by ceruloplasmin in a specified sample of blood. The rate of formation of the colored oxidation product is proportional to the concentration of serum ceruloplasmin when a correction is made for nonenzymatic oxidation of p-phenylenediamine (PPD)." [PMID:5473551]
synonym: "blood PPD oxidase activity assay" EXACT []
is_a: MMO:0000429 ! blood enzyme activity assay
created_by: slaulede
creation_date: 2020-07-14T13:28:09Z

[Term]
id: MMO:0000727
name: plasma p-phenylenediamine oxidase activity assay
def: "A method which quantifies the catalytic effect exerted by ceruloplasmin in a specified sample of plasma. The rate of formation of the colored oxidation product is proportional to the concentration of ceruloplasmin when a correction is made for nonenzymatic oxidation of p-phenylenediamine (PPD)." [PMID:5473551]
synonym: "plasma PPD oxidase activity assay" EXACT []
is_a: MMO:0000726 ! blood p-phenylenediamine oxidase activity assay
created_by: slaulede
creation_date: 2020-07-14T13:33:41Z

[Term]
id: MMO:0000728
name: serum p-phenylenediamine oxidase activity assay
def: "A method which quantifies the catalytic effect exerted by ceruloplasmin in a specified sample of serum. The rate of formation of the colored oxidation product is proportional to the concentration of ceruloplasmin when a correction is made for nonenzymatic oxidation of p-phenylenediamine (PPD)." [PMID:5473551]
synonym: "serum PPD oxidase activity assay" EXACT []
is_a: MMO:0000726 ! blood p-phenylenediamine oxidase activity assay
created_by: slaulede
creation_date: 2020-07-14T13:35:48Z

[Term]
id: MMO:0000729
name: flame photometry
def: "This is a controlled flame test with the intensity of the flame color quantified by photoelectric circuitry. The intensity of the color will depend on the energy that had been absorbed by the atoms that was sufficient to vaporize them. Filters select which colors the photometer detects and exclude the influence of other ions." [https://en.wikipedia.org/wiki/Photoelectric_flame_photometer "Wikipedia"]
is_a: MMO:0000704 ! photometry
created_by: slaulede
creation_date: 2020-07-16T10:29:04Z

[Term]
id: MMO:0000730
name: o-Phthalaldehyde fluorescent protein assay
def: "When reacted with primary amines in the presence of mercaptoethanol, OPA (o-Phthalaldehyde) yields an intense blue-colored fluorescent product that has a maximum wavelength of excitation of 340 nm and emission at 455 nm. Wavelengths from 330-375 nm have been used for excitation and 436-490 nm for measuring emission. Protein concentrations as low as 50 ng/ml can be measured with an OPA assay. The inherent sensitivity and speed of OPA, along with its broad linear range, makes it a useful protein and peptide assay reagent." [http://www.piercenet.com, PMID:5576608]
synonym: "OPA fluorescent protein assay" EXACT []
is_a: MMO:0000247 ! fluorometry
created_by: slaulede
creation_date: 2020-08-04T17:55:00Z

[Term]
id: MMO:0000731
name: nociception measurement method
def: "A nociception assay that evaluates the ability of an animal, usually a rodent, to detect a noxious stimulus such as the feeling of pain, caused by stimulation of nociceptors. These assays measure the existence of pain through behaviors such as withdrawal, licking, immobility, and vocalization." []
is_obsolete: true
created_by: slaulede
creation_date: 2020-09-25T12:22:24Z

[Term]
id: MMO:0000732
name: nociception measurement method
alt_id: MMO:0000731
def: "A method to measure nociception, the sensory nervous system's process of encoding noxious stimuli. In nociception, intense chemical, mechanical, or thermal stimulation of sensory nerve cells called nociceptors produces a signal that travels along a chain of nerve fibers via the spinal cord to the brain." [https://en.wikipedia.org/wiki/Nociception, https://www.physio-pedia.com/Nociception]
synonym: "nociception assay" EXACT []
synonym: "pain measurement method" RELATED []
is_a: MMO:0000737 ! sensation test
created_by: slaulede
creation_date: 2020-09-25T12:36:27Z

[Term]
id: MMO:0000733
name: Randall-Selitto test
def: "The Randall-Selitto test consists of an application of a uniformly increasing pressure on the paw to assess the threshold response to pain." [https://en.wikipedia.org/wiki/Nociception, https://www.panlab.com/en/tests-solutions/randall-selitto-test, PMID:13471093]
synonym: "paw pressure test" EXACT []
xref: PMID:13471093
xref: PMID:21682605
is_a: MMO:0000732 ! nociception measurement method
created_by: slaulede
creation_date: 2020-09-25T13:11:24Z

[Term]
id: MMO:0000734
name: automated plasma triglyceride analysis
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure triglyceride in plasma." [https://www.merriam-webster.com/, ISBN-13:978-0781733908]
is_a: MMO:0000038 ! blood lipid analysis
is_a: MMO:0000234 ! plasma triglyceride analysis
created_by: slaulede
creation_date: 2020-09-29T17:25:28Z

[Term]
id: MMO:0000735
name: automated plasma glucose analysis
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure glucose in plasma." [https://www.merriam-webster.com/]
is_obsolete: true
created_by: slaulede
creation_date: 2020-09-29T17:34:41Z

[Term]
id: MMO:0000736
name: inductively coupled plasma mass spectrometry
def: "Inductively coupled plasma mass spectrometry is an elemental analysis technology capable of detecting most of the periodic table of elements at milligram to nanogram levels per liter. The Inductively coupled plasma is an ionization source that fully decomposes a sample into its constituent elements and transforms those elements into ions." [https://www.sciencedirect.com/topics/neuroscience/inductively-coupled-plasma-mass-spectrometry, https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/spectroscopy-elemental-isotope-analysis-learning-center/trace-elemental-analysis-tea-information/inductively-coupled-plasma-mass-spectrometry-icp-ms-information.html]
synonym: "ICP-MS" EXACT []
xref: PMID:22661893
is_a: MMO:0000534 ! mass spectrometry
created_by: slaulede
creation_date: 2020-10-08T17:05:28Z

[Term]
id: MMO:0000737
name: sensation test
def: "A determination of exteroceptive sensation (touch, temperature, pain), proprioceptive sensation (joint position, vibration) , or cortical sensory functions." [https://www.ncbi.nlm.nih.gov/books/NBK390/]
is_a: MMO:0000026 ! in vivo method
created_by: slaulede
creation_date: 2020-10-13T12:26:21Z

[Term]
id: MMO:0000738
name: esthesiometry
def: "The measurement of sensory, usually tactile, discrimination." [https://eyewiki.aao.org/Corneal_Esthesiometry#cite_note-Webster-1, https://www.merriam-webster.com/]
is_a: MMO:0000737 ! sensation test
created_by: slaulede
creation_date: 2020-10-13T12:34:10Z

[Term]
id: MMO:0000739
name: corneal sensitivity test  using a Cochet-Bonnet esthesiometer
def: "A rapid corneal sensitivity examination based upon the principle of pressure transmitted axially by a nylon monofilament, of known diameter but of variable length, for a given bending stress. The handheld device used to measure the sensation is called a Cochet-Bonnet or Luneau Cochet-Bonnet esthesiometer." [https://eyewiki.aao.org/Corneal_Esthesiometry, https://www.west-op.com/aesthesiometer.html]
synonym: "CB test" EXACT []
is_a: MMO:0000740 ! corneal esthesiometry
created_by: slaulede
creation_date: 2020-10-13T12:43:46Z

[Term]
id: MMO:0000740
name: corneal esthesiometry
def: "This qualitative or quantitative measurement of tactile sensation by the cornea may involve contact or non-contact procedures." [https://eyewiki.aao.org/Corneal_Esthesiometry]
synonym: "corneal aesthesiometry" EXACT []
is_a: MMO:0000738 ! esthesiometry
created_by: slaulede
creation_date: 2020-10-13T13:06:07Z

[Term]
id: MMO:0000741
name: Schirmer test
def: "This test is used to determine if the subject's tear glands produce enough tears to keep the eyes moist. It involves the placement of one end of a calibrated filter strip inside the lower eyelid to collect and measure tear production." [https://www.healthline.com/health/schirmers-test, https://www.hopkinssjogrens.org/disease-information/diagnosis-sjogrens-syndrome/schirmers-test/]
synonym: "basal secretion test" EXACT []
synonym: "dry eye test" EXACT []
synonym: "Schirmer's test" EXACT []
synonym: "tearing test" EXACT []
synonym: "tear test" EXACT []
is_a: MMO:0000235 ! body fluid collection method
created_by: slaulede
creation_date: 2020-10-13T13:17:04Z

[Term]
id: MMO:0000742
name: multiphoton microscopy
def: "Multiphoton microscopy (MPM) is an imaging technique that allows intact biological samples to be visualized at high resolution. MPM is based on nonlinear optical processes such as two-photon and three-photon excited fluorescence (2PEF, 3PEF) and second and third harmonic generation (SHG, THG). Most commonly, 2PEF and 3PEF are used to image fluorescent dyes or endogenous molecules." [http://www.biophotonics.illinois.edu]
synonym: "MPM" EXACT []
xref: PMID:25680709
is_a: MMO:0000743 ! in vivo microscopy
created_by: slaulede
creation_date: 2021-01-15T13:32:33Z

[Term]
id: MMO:0000743
name: in vivo microscopy
def: "In vivo microscopy (IVM) encompassess a variety of techniques which capture microscopic images in living subjects. IVM imaging technologies can produce 2D or 3D (tomographic) images." [https://www.cap.org, PMID:30525931]
synonym: "IVM" EXACT []
xref: PMID:30525931
is_a: MMO:0000026 ! in vivo method
created_by: slaulede
creation_date: 2021-01-15T14:29:02Z

[Term]
id: MMO:0000744
name: blood corticosterone analysis
def: "A method which measures corticosterone in the blood. Corticosterone is a corticosteroid produced in the adrenal cortex that acts in the metabolism of carbohydrates and proteins, functioning as both a mineralocorticoid and a glucocorticoid." [https://www.merriam-webster.com/, MESH:D003345]
xref: CHEBI:16827
xref: MESH:D003345
xref: PMID:16929957
is_a: MMO:0000311 ! blood hormone analysis
created_by: slaulede
creation_date: 2021-02-22T14:52:28Z

[Term]
id: MMO:0000745
name: plasma corticosterone analysis
def: "A method which measures corticosterone in the plasma. Corticosterone is a corticosteroid produced in the adrenal cortex that acts in the metabolism of carbohydrates and proteins, functioning as both a mineralocorticoid and a glucocorticoid." [ISBN:978-1416049982, MESH:D003345]
xref: CHEBI:16827
xref: MESH:D003345
xref: PMID:16929957
is_a: MMO:0000744 ! blood corticosterone analysis
created_by: slaulede
creation_date: 2021-02-22T14:58:20Z

[Term]
id: MMO:0000746
name: serum corticosterone analysis
def: "A method which measures corticosterone in the serum. Corticosterone is a corticosteroid produced in the adrenal cortex that acts in the metabolism of carbohydrates and proteins, functioning as both a mineralocorticoid and a glucocorticoid." [BN:978-1416049982, MESH:D003345]
synonym: "CHEBI:16827" EXACT []
synonym: "MESH:D003345" EXACT []
synonym: "PMID:16929957" EXACT []
is_a: MMO:0000744 ! blood corticosterone analysis
created_by: slaulede
creation_date: 2021-02-22T15:06:56Z

[Term]
id: MMO:0000747
name: blood 11-dehydrocorticosterone analysis
def: "A method which measures 11-dehydrocorticosterone in the blood. 11-dehydrocorticosterone is an 11-oxo steroid that is corticosterone in which the hydroxy substituent at the 11beta position has been oxidized to give the corresponding ketone." [CHEBI:78600]
xref: CHEBI:78600
xref: MESH:C003552
xref: PMID:16929957
is_a: MMO:0000744 ! blood corticosterone analysis
created_by: slaulede
creation_date: 2021-02-22T15:11:13Z

[Term]
id: MMO:0000748
name: plasma 11-dehydrocorticosterone analysis
def: "A method which measures 11-dehydrocorticosterone in the plasma. 11-dehydrocorticosterone is an 11-oxo steroid that is corticosterone in which the hydroxy substituent at the 11beta position has been oxidized to give the corresponding ketone." [CHEBI:78600]
xref: CHEBI:78600
xref: MESH:C003552
xref: PMID:16929957
is_a: MMO:0000745 ! plasma corticosterone analysis
is_a: MMO:0000747 ! blood 11-dehydrocorticosterone analysis
created_by: slaulede
creation_date: 2021-02-22T15:15:28Z

[Term]
id: MMO:0000749
name: serum 11-dehydrocorticosterone analysis
def: "A method which measures 11-dehydrocorticosterone in the serum. 11-dehydrocorticosterone is an 11-oxo steroid that is corticosterone in which the hydroxy substituent at the 11beta position has been oxidized to give the corresponding ketone." [CHEBI:78600]
xref: CHEBI:78600
xref: MESH:C003552
xref: PMID:16929957
is_a: MMO:0000746 ! serum corticosterone analysis
is_a: MMO:0000747 ! blood 11-dehydrocorticosterone analysis
created_by: slaulede
creation_date: 2021-02-22T15:18:32Z

[Term]
id: MMO:0000750
name: total organ perfusion and parasite count
def: "A procedure or technique performed outside the living body of a higher organism by which parasites are removed from an organ and enumerated." [https://www.merriam-webster.com/]
xref: PMID:1719096
is_a: MMO:0000562 ! ex vivo microbiological method
created_by: slaulede
creation_date: 2021-03-19T09:19:22Z

[Term]
id: MMO:0000751
name: immunofluorescence confocal microscopy with digital image analysis
def: "A method which incorporates use of immunofluorescence confocal microscopy to produce picture files stored as data expressed in a discrete numerical form, followed by use of computer software to evaluate these resulting microscopic images." [https://ibidi.com/content/216-confocal-microscopy, https://www.merriam-webster.com/]
xref: PMID:22871889
is_a: MMO:0000686 ! immunofluorescence confocal microscopy
created_by: slaulede
creation_date: 2021-03-19T12:03:14Z

[Term]
id: MMO:0000752
name: von Frey assay
def: "This is a test introduced by physiologist Maximilian von Frey and modified by Weinstein, to evaluate mechanical allodynia in mice and rats. The test, which may be manual or electronic, uses von Frey hair or fibers, which are small pieces of nylon rod, approximately 50 mm in length, and of varying diameters, to test a rodent's sensitivity to a mechanical stimulus." [https://en.wikipedia.org/wiki/Nociception_assay, PMID:28932184]
synonym: "von Frey test" EXACT []
xref: PMID:24388923
is_a: MMO:0000732 ! nociception measurement method
created_by: slaulede
creation_date: 2021-03-25T17:10:33Z

[Term]
id: MMO:0000753
name: probit analysis estimate
def: "In statistics, a probit model is a type of regression where the dependent variable can take only two values, for example married or not married. The word is a portmanteau, coming from probability + unit. The purpose of the model is to estimate the probability that an observation with particular characteristics will fall into a specific one of the categories. This procedure will allow you to estimate the strength of a stimulus required to induce a certain proportion of responses, such as the median effective dose." [https://en.wikipedia.org/wiki/Probit_model, https://www.ibm.com/docs/en/spss-statistics/24.0.0?topic=option-probit-analysis#\:~\:text=The%20probit%20analysis%20procedure%20reports%20estimates%20of%20effective\,reports%20estimates%20of%20odds%20ratios%20for%20independent%20variables.]
xref: PMID:30575429
is_a: MMO:0000575 ! computational method
created_by: slaulede
creation_date: 2021-05-04T17:45:28Z

[Term]
id: MMO:0000754
name: optokinetic reflex test method
def: "This testing method may involve an optokinetic drum, a strip of paper with alternating 2-inch black/colored and white strips, or a mirror used to rotate across the subject's visual field. Any of the options may be passed in front of the subject's eye(s). The subject looks at the object as it rapidly moves by. The time between cycles of the eye(s) repositioning to the original position is recorded." [https://eyewiki.org/Reflexes_and_the_Eye#Optokinetic_reflex, https://psychology.wikia.org/wiki/Optokinetic_reflex#\:~\:text=The%20optokinetic%20reflex%20is%20a%20combination%20of%20a\,was%20in%20when%20it%20first%20saw%20the%20object., https://www.sciencedirect.com/topics/neuroscience/optokinetic-reflex]
synonym: "alternating stripe method" NARROW []
synonym: "OKR test method" EXACT []
synonym: "optokinetic drum method" NARROW []
xref: PMID:28441076
is_a: MMO:0000026 ! in vivo method
created_by: slaulede
creation_date: 2021-06-18T18:31:15Z

[Term]
id: MMO:0000755
name: anorectal manometry
def: "This is a technique used to measure contractility in the anus and rectum. This technique uses a balloon in the rectum to distend the rectum, a pressure sensor at the internal anal sphincter, and a pressure transducer connected to a recording device." [https://en.wikipedia.org/wiki/Anorectal_manometry, PMID:29391927]
synonym: "anal manometry" EXACT []
xref: PMID:29391927
is_a: MMO:0000040 ! dynamometry
created_by: slaulede
creation_date: 2021-07-13T10:50:58Z

[Term]
id: MMO:0000756
name: albumin blue 580-based urine albumin analysis with spectrophotometric readout
def: "The dye albumin blue 580 specifically binds to albumin with exhibition of strong red fluorescence. The albumin concentration is calculated from emission intensity at 616 nm (excitation at 590 nm) and a calibration curve." [PMID:9177738, PMID:9191552]
synonym: "albumin blue 580-based urine albumin analysis" EXACT []
xref: PMID:9191552
is_a: MMO:0000406 ! urine albumin analysis
is_a: MMO:0000423 ! urine protein colorimetric analysis
created_by: slaulede
creation_date: 2021-07-15T18:10:43Z

[Term]
id: MMO:0000757
name: in vivo videography with digital image analysis
def: "The process of producing moving images of an entire living organism, or of a part of a living organism such as an organ or tissue recorded in situ, by the action of radiant energy and especially light on a sensitive surface such as film or an optical sensor followed by use of computer software to analyze or assist in the analysis of the resulting images." [https://www.merriam-webster.com/, PMID:28341233]
synonym: "in vivo videodocumentation with digital image analysis" EXACT []
synonym: "videography of in vivo subject with digital image analysis" EXACT []
xref: PMID:28341233
is_a: MMO:0000409 ! in vivo photography with digital image analysis
created_by: slaulede
creation_date: 2021-07-26T14:42:12Z

[Term]
id: MMO:0000758
name: multiphase pCASL MRI
def: "Multiphase pCASL is a variant of ASL where instead of acquiring the traditional label and control images, images are acquired following labeling with radio-frequency (RF) pulses at multiple phase increments. Arterial spin labeling (ASL) perfusion is a MRI technique to quantify tissue blood flow. ASL is a non-invasive technique that labels the protons in the arterial blood by radiofrequency pulses, without the exogenous injection of contrast media." [https://doi.org/10.1016/j.diii.2013.06.010, PMID:29498562]
synonym: "arterial spin labelling (ASL) MRI" EXACT []
synonym: "arterial spin labelling magnetic resonance imaging" EXACT []
synonym: "MP pCASL" EXACT []
synonym: "multiphase pseudo-continuous arterial spin labelling magnetic resonance imaging" EXACT []
xref: PMID:29498562
is_a: MMO:0000019 ! magnetic resonance imaging
created_by: slaulede
creation_date: 2021-07-29T16:51:13Z

[Term]
id: MMO:0000759
name: autoradiography
def: "This is an imaging technique which records on a photographic plate the radiation emitted by radioactive material within an object or tissue, which is in close contact with the photographic emulsion." [https://www.merriam-webster.com/, https://www.sciencedirect.com/topics/chemistry/autoradiography, MESH:D001345]
xref: PMID:29498562
is_a: MMO:0000124 ! in vivo radiography
is_a: MMO:0000366 ! ex vivo radiography
created_by: slaulede
creation_date: 2021-07-29T18:16:26Z

[Term]
id: MMO:0000760
name: computerized assessment of in vivo video recording
def: "A procedure or technique in which a morphological or physiological state or property of a living body or in situ body part is evaluated, appraised or perceived through an algorithmic analysis of a stored image-based record of the organism, body or body part, for example a videotape or a stored video file." [https://www.merriam-webster.com/, ISBN-13:9780781733908]
synonym: "computer tracking system" EXACT []
xref: PMID:16837653
is_a: MMO:0000163 ! in vivo visual assessment
created_by: slaulede
creation_date: 2021-09-09T14:54:52Z

[Term]
id: MMO:0000761
name: Morris water maze with computer analysis of video recording
def: "This is an experimental method in which a subject is placed in an open pool of water with a submerged escape platform and the subject's movements are video recorded. These movements are then evaluated, appraised or perceived through computerized analysis." [https://www.merriam-webster.com/, ISBN-13:9780781733908]
synonym: "Morris water maze with computer tracking system" EXACT []
xref: PMID:16837653
is_a: MMO:0000760 ! computerized assessment of in vivo video recording
created_by: slaulede
creation_date: 2021-09-09T15:14:23Z

[Term]
id: MMO:0000762
name: serum creatinine analysis by Jaffe reaction with spectrophotometric readout
def: "A method for assaying the creatinine in serum (blood plasma from which fibrinogen has been removed.) using the Jaffe reaction, the reaction of creatinine and picric acid in an alkaline solution, followed by quantitation of the colorimetric readout using a spectrophotometer at 520 nm." [https://med.libretexts.org/Bookshelves/Allied_Health/Book%3A_Clinical_Chemistry_-_Theory_Analysis_Correlation_(Kaplan_and_Pesce)/02%3A_Laboratory_Exercises/2.14%3A_Serum_Creatinine_(Jaffe_Method)]
synonym: "alkaline picrate serum creatinine assay with spectrophotometric readout" EXACT []
xref: PMID:13072520
is_a: MMO:0000271 ! serum creatinine analysis
is_a: MMO:0000542 ! creatinine analysis by Jaffe reaction with spectrophotometric readout
created_by: slaulede
creation_date: 2021-09-14T15:36:57Z

[Term]
id: MMO:0000763
name: urine creatinine analysis by Jaffe reaction with deproteinization and spectrophotometric readout
def: "A method for assaying creatinine in deproteinized urine (urine from which excess proteins have been removed) using the Jaffe reaction, the reaction of creatinine and picric acid in an alkaline solution, followed by quantitation of the colorimetric readout using a spectrophotometer at 520 nm." [https://med.libretexts.org/Bookshelves/Allied_Health/Book%3A_Clinical_Chemistry_-_Theory_Analysis_Correlation_(Kaplan_and_Pesce)/02%3A_Laboratory_Exercises/2.14%3A_Serum_Creatinine_(Jaffe_Method)]
synonym: "alkaline picrate urine creatinine assay with deproteinization and spectrophotometric readout" EXACT []
xref: PMID:7411020
is_a: MMO:0000543 ! urine creatinine analysis by Jaffe reaction with spectrophotometric readout
created_by: slaulede
creation_date: 2021-09-14T16:38:27Z

[Term]
id: MMO:0000764
name: urine creatinine analysis by Jaffe reaction without deproteinization and spectrophotometric readout
def: "A method for assaying the creatinine in urine from which excess proteins have not been removed, using the Jaffe reaction, the reaction of creatinine and picric acid in an alkaline solution, followed by quantitation of the colorimetric readout using a spectrophotometer at 520 nm." [https://med.libretexts.org/Bookshelves/Allied_Health/Book%3A_Clinical_Chemistry_-_Theory_Analysis_Correlation_(Kaplan_and_Pesce)/02%3A_Laboratory_Exercises/2.14%3A_Serum_Creatinine_(Jaffe_Method)]
synonym: "alkaline picrate urine creatinine assay without deproteinization and spectrophotometric readout" EXACT []
xref: PMID:19420905
is_a: MMO:0000543 ! urine creatinine analysis by Jaffe reaction with spectrophotometric readout
created_by: slaulede
creation_date: 2021-09-14T16:47:26Z

[Term]
id: MMO:0000765
name: scintigraphy
def: "This is a diagnostic technique in which a two-dimensional picture of internal body tissue is produced through the detection of radiation emitted by a radioactive tracer introduced into the body of the subject." [https://www.merriam-webster.com/, ISBN-13:9780781733908]
synonym: "gamma scan" EXACT []
xref: PMID:30208622
is_a: MMO:0000124 ! in vivo radiography
created_by: slaulede
creation_date: 2021-10-04T17:00:16Z

[Term]
id: MMO:0000766
name: Na+/K+ ATPase activity assay
def: "A method which quantifies the catalytic effect exerted by Na+/K+ ATPase, an enzyme found in all animal cells which helps maintain resting potential, affects transport, and regulates cellular volume." [https://en.wikipedia.org/wiki/Na%2B/K%2B-ATPase]
synonym: "Na⁺/K⁺ pump assay" EXACT []
synonym: "ouabain-sensitive Na⁺/K⁺ pump assay" EXACT []
synonym: "sodium-potassium adenosine triphosphatase assay" EXACT []
synonym: "sodium-potassium pump assay" EXACT []
xref: PMID:12887131
xref: PMID:3611769
is_a: MMO:0000444 ! enzyme or transport activity assay
created_by: slaulede
creation_date: 2021-11-01T17:04:07Z

[Term]
id: MMO:0000767
name: Na+/K+ ATPase activity assay in Mg++ medium
def: "A method which quantifies the catalytic effect exerted by Na+/K+ ATPase in a medium supplemented with magnesium ions. Na+/K+ ATPase is an enzyme found in all animal cells which helps maintain resting potential, affects transport, and regulates cellular volume." [https://en.wikipedia.org/wiki/Na%2B/K%2B-ATPase]
synonym: "Na⁺/K⁺ pump assay in Mg++ medium" EXACT []
synonym: "sodium-potassium adenosine triphosphatase assay in Mg++ medium" EXACT []
synonym: "sodium-potassium pump assay in Mg++ medium" EXACT []
xref: PMID:12887131
xref: PMID:3611769
is_a: MMO:0000766 ! Na+/K+ ATPase activity assay
created_by: slaulede
creation_date: 2021-11-01T17:15:00Z

[Term]
id: MMO:0000768
name: Na+/K+ ATPase activity assay in choline medium
def: "A method which quantifies the catalytic effect exerted by Na+/K+ ATPase in a medium supplemented with choline. Na+/K+ ATPase is an enzyme found in all animal cells which helps maintain resting potential, affects transport, and regulates cellular volume." [https://en.wikipedia.org/wiki/Na%2B/K%2B-ATPase]
synonym: "Na⁺/K⁺ pump assay in choline medium" EXACT []
synonym: "sodium-potassium adenosine triphosphatase assay in choline medium" EXACT []
synonym: "sodium-potassium pump assay in choline medium" EXACT []
xref: PMID:12887131
xref: PMID:3611769
is_a: MMO:0000766 ! Na+/K+ ATPase activity assay
created_by: slaulede
creation_date: 2021-11-01T17:22:46Z

[Term]
id: MMO:0000769
name: Na-K-Cl cotransport activity assay
def: "A method which quantifies the ion transporting effect exerted by Na-K-Cl cotransporters, membrane transport proteins which transport sodium (Na), potassium (K), and chloride (Cl) ions across cell membranes." [https://en.wikipedia.org/wiki/Na-K-Cl_cotransporter]
synonym: "bumetanide-sensitive sodium flux assay" EXACT []
synonym: "Na-K-Cl symporter activity assay" EXACT []
synonym: "sodium-potassium-chloride symporter activity assay" EXACT []
xref: PMID:12887131
xref: PMID:3611769
is_a: MMO:0000444 ! enzyme or transport activity assay
created_by: slaulede
creation_date: 2021-11-01T17:48:59Z

[Term]
id: MMO:0000770
name: Na-K-Cl cotransport activity assay in choline medium
def: "A method which quantifies the ion transporting effect exerted by Na-K-Cl cotransporters in a medium supplemented with choline. Na-K-Cl symporters transport sodium (Na), potassium (K), and chloride (Cl) ions across cell membranes. This assay substitutes choline for potassium." [https://en.wikipedia.org/wiki/Na-K-Cl_cotransporter, PMID:3611769]
synonym: "bumetanide-sensitive sodium flux assay in choline medium" EXACT []
synonym: "Na-K-Cl symporter activity assay in choline medium" EXACT []
synonym: "sodium-potassium-chloride symporter activity assay in choline medium" EXACT []
xref: PMID:3611769
is_a: MMO:0000769 ! Na-K-Cl cotransport activity assay
created_by: slaulede
creation_date: 2021-11-01T18:09:38Z

[Term]
id: MMO:0000771
name: Na-K-Cl cotransport activity assay in Mg++ medium
def: "A method which quantifies the ion transporting effect exerted by Na-K-Cl cotransporters in a medium supplemented with magnesium ions. Na-K-Cl symporters transport sodium (Na), potassium (K), and chloride (Cl) ions across cell membranes." [https://en.wikipedia.org/wiki/Na-K-Cl_cotransporter, PMID:3611769]
synonym: "bumetanide-sensitive sodium flux assay in Mg++ medium" EXACT []
synonym: "Na-K-Cl symporter activity assay in Mg++ medium" EXACT []
synonym: "sodium-potassium-chloride symporter activity assay in Mg++ medium" EXACT []
xref: PMID:3611769
is_a: MMO:0000769 ! Na-K-Cl cotransport activity assay
created_by: slaulede
creation_date: 2021-11-01T18:16:31Z

[Term]
id: MMO:0000772
name: Na+ passive permeability assay
def: "A method which quantifies the net effect of blocking both Na-K-Cl cotransporters and the Na/K pump, membrane transport proteins/enzymes which transport sodium (Na), potassium (K), and chloride (Cl) ions across cell membranes. The Na+ passive permeability assay essentially measures Na+ and/or K+ leak into cells." [https://en.wikipedia.org/wiki/Na%2B/K%2B-ATPase, https://en.wikipedia.org/wiki/Na-K-Cl_cotransporter, PMID:3611769]
synonym: "bumetanide-ouabain resistant cation leak assay" EXACT []
synonym: "bumetanide-ouabain resistant pathway assay" EXACT []
synonym: "passive membrane permeability assay" EXACT []
xref: PMID:12887131
xref: PMID:3611769
is_a: MMO:0000444 ! enzyme or transport activity assay
created_by: slaulede
creation_date: 2021-11-01T18:41:22Z

[Term]
id: MMO:0000773
name: Na+/K+ ATPase activity assay in isotonic choline medium
def: "A method which quantifies the catalytic effect exerted by Na+/K+ ATPase in an isotonic choline medium (295 mOsm). Na+/K+ ATPase is an enzyme found in all animal cells which helps maintain resting potential, affects transport, and regulates cellular volume." [https://en.wikipedia.org/wiki/Na%2B/K%2B-ATPase]
synonym: "Na⁺/K⁺ pump assay in isotonic choline medium" EXACT []
synonym: "sodium-potassium adenosine triphosphatase assay in isotonic choline medium" EXACT []
synonym: "sodium-potassium pump assay in isotonic choline medium" EXACT []
xref: PMID:12887131
xref: PMID:3611769
is_a: MMO:0000768 ! Na+/K+ ATPase activity assay in choline medium
created_by: slaulede
creation_date: 2021-11-02T13:51:50Z

[Term]
id: MMO:0000774
name: Na+/K+ ATPase activity assay in hypotonic choline medium
def: "A method which quantifies the catalytic effect exerted by Na+/K+ ATPase in a hypotonic choline medium (170 mOsm). Na+/K+ ATPase is an enzyme found in all animal cells which helps maintain resting potential, affects transport, and regulates cellular volume" [https://en.wikipedia.org/wiki/Na%2B/K%2B-ATPase]
synonym: "Na⁺/K⁺ pump assay in hypotonic choline medium" EXACT []
synonym: "sodium-potassium adenosine triphosphatase assay in hypotonic" EXACT []
synonym: "sodium-potassium pump assay in isotonic hypotonic medium" EXACT []
xref: PMID:12887131
xref: PMID:3611769
is_a: MMO:0000768 ! Na+/K+ ATPase activity assay in choline medium
created_by: slaulede
creation_date: 2021-11-02T14:16:38Z

[Term]
id: MMO:0000775
name: Na-K-Cl cotransport activity assay in isotonic choline medium
def: "A method which quantifies the ion transporting effect exerted by Na-K-Cl cotransporters in an isotonic choline medium (295 mOsm). Na-K-Cl symporters transport sodium (Na), potassium (K), and chloride (Cl) ions across cell membranes." [https://en.wikipedia.org/wiki/Na-K-Cl_cotransporter, PMID:3611769]
synonym: "bumetanide-sensitive sodium flux assay in isotonic choline medium" EXACT []
synonym: "Na-K-Cl symporter activity assay in isotonic choline medium" EXACT []
synonym: "sodium-potassium-chloride symporter activity assay in isotonic choline medium" EXACT []
xref: PMID:3611769
is_a: MMO:0000770 ! Na-K-Cl cotransport activity assay in choline medium
created_by: slaulede
creation_date: 2021-11-02T14:21:59Z

[Term]
id: MMO:0000776
name: Na-K-Cl cotransport activity assay in hypotonic choline medium
def: "A method which quantifies the ion transporting effect exerted by Na-K-Cl cotransporters in a hypotonic choline medium (170 mOsm). Na-K-Cl symporters transport sodium (Na), potassium (K), and chloride (Cl) ions across cell membranes." [https://en.wikipedia.org/wiki/Na-K-Cl_cotransporter, PMID:3611769]
synonym: "bumetanide-sensitive sodium flux assay in hypotonic choline medium" EXACT []
synonym: "Na-K-Cl symporter activity assay in hypotonic choline medium" EXACT []
synonym: "sodium-potassium-chloride symporter activity assay in hypotonic choline medium" EXACT []
xref: PMID:3611769
is_a: MMO:0000770 ! Na-K-Cl cotransport activity assay in choline medium
created_by: slaulede
creation_date: 2021-11-02T14:27:45Z

[Term]
id: MMO:0000777
name: Na+ passive permeability assay in Mg++ medium
def: "A method which quantifies, in a medium supplemented with magnesium ions, the net effect of blocking both Na-K-Cl cotransporters and the Na/K pump, membrane transport proteins/enzymes which transport sodium (Na), potassium (K), and chloride (Cl) ions across cell membranes. The Na+ passive permeability assay essentially measures Na+ and/or K+ leak into cells." [https://en.wikipedia.org/wiki/Na%2B/K%2B-ATPase, https://en.wikipedia.org/wiki/Na-K-Cl_cotransporter, PMID:3611769]
synonym: "bumetanide-ouabain resistant cation leak assay in Mg++ medium" EXACT []
synonym: "bumetanide-ouabain resistant pathway assay in Mg++ medium" EXACT []
xref: PMID:12887131
xref: PMID:3611769
is_a: MMO:0000772 ! Na+ passive permeability assay
created_by: slaulede
creation_date: 2021-11-02T14:44:11Z

[Term]
id: MMO:0000778
name: Na+ passive permeability assay in choline medium
def: "A method which quantifies, in a medium supplemented with choline, the net effect of blocking both Na-K-Cl cotransporters and the Na/K pump, membrane transport proteins/enzymes which transport sodium (Na), potassium (K), and chloride (Cl) ions across cell membranes. The Na+ passive permeability assay essentially measures Na+ and/or K+ leak into cells." [https://en.wikipedia.org/wiki/Na%2B/K%2B-ATPase, https://en.wikipedia.org/wiki/Na-K-Cl_cotransporter, PMID:3611769]
synonym: "bumetanide-ouabain resistant cation leak assay in choline medium" EXACT []
synonym: "bumetanide-ouabain resistant pathway assay in choline medium" EXACT []
xref: PMID:12887131
xref: PMID:3611769
is_a: MMO:0000772 ! Na+ passive permeability assay
created_by: slaulede
creation_date: 2021-11-02T14:59:00Z

[Term]
id: MMO:0000779
name: Na+ passive permeability assay in isotonic choline medium
def: "A method which quantifies, in an isotonic choline medium (295 mOsm), the net effect of blocking both Na-K-Cl cotransporters and the Na/K pump, membrane transport proteins/enzymes which transport sodium (Na), potassium (K), and chloride (Cl) ions across cell membranes. The Na+ passive permeability assay essentially measures Na+ and/or K+ leak into cells." [https://en.wikipedia.org/wiki/Na%2B/K%2B-ATPase, https://en.wikipedia.org/wiki/Na-K-Cl_cotransporter, PMID:3611769]
synonym: "bumetanide-ouabain resistant cation leak assay in isotonic choline medium" EXACT []
synonym: "bumetanide-ouabain resistant pathway assay in isotonic choline medium" EXACT []
xref: PMID:12887131
xref: PMID:3611769
is_a: MMO:0000778 ! Na+ passive permeability assay in choline medium
created_by: slaulede
creation_date: 2021-11-02T15:16:43Z

[Term]
id: MMO:0000780
name: Na+ passive permeability assay in hypotonic choline medium
def: "A method which quantifies, in a hypotonic choline medium (170 mOsm), the net effect of blocking both Na-K-Cl cotransporters and the Na/K pump, membrane transport proteins/enzymes which transport sodium (Na), potassium (K), and chloride (Cl) ions across cell membranes. The Na+ passive permeability assay essentially measures Na+ and/or K+ leak into cells." [https://en.wikipedia.org/wiki/Na%2B/K%2B-ATPase, https://en.wikipedia.org/wiki/Na-K-Cl_cotransporter, PMID:3611769]
synonym: "bumetanide-ouabain resistant cation leak assay in hypotonic choline medium" EXACT []
synonym: "bumetanide-ouabain resistant pathway assay in hypotonic choline medium" EXACT []
xref: PMID:12887131
xref: PMID:3611769
is_a: MMO:0000778 ! Na+ passive permeability assay in choline medium
created_by: slaulede
creation_date: 2021-11-02T15:20:19Z

[Term]
id: MMO:0000781
name: Na-K-Cl cotransport activity assay in nitrate medium
def: "A method which quantifies the ion transporting effect exerted by Na-K-Cl cotransporters in a medium supplemented with nitrate. Na-K-Cl symporters transport sodium (Na), potassium (K), and chloride (Cl) ions across cell membranes. This assay substitutes nitrate for chloride." [https://en.wikipedia.org/wiki/Na-K-Cl_cotransporter, PMID:1390856]
synonym: "bumetanide-sensitive sodium flux assay in nitrate medium" EXACT []
synonym: "Na-K-Cl symporter activity assay in nitrate medium" EXACT []
synonym: "sodium-potassium-chloride symporter activity assay in nitrate medium" EXACT []
xref: PMID:1390856
is_a: MMO:0000769 ! Na-K-Cl cotransport activity assay
created_by: slaulede
creation_date: 2021-11-04T13:45:37Z

[Term]
id: MMO:0000782
name: Na-K-Cl cotransport activity assay in sulfate medium
def: "A method which quantifies the ion transporting effect exerted by Na-K-Cl cotransporters in a medium supplemented with sulfate. Na-K-Cl symporters transport sodium (Na), potassium (K), and chloride (Cl) ions across cell membranes. This assay substitutes sulfate for chloride." [https://en.wikipedia.org/wiki/Na-K-Cl_cotransporter, PMID:1390856]
synonym: "bumetanide-sensitive sodium flux assay in sulfate medium" EXACT []
synonym: "Na-K-Cl symporter activity assay in sulfate medium" EXACT []
synonym: "sodium-potassium-chloride symporter activity assay in sulfate medium" EXACT []
xref: PMID:1390856
is_a: MMO:0000769 ! Na-K-Cl cotransport activity assay
created_by: slaulede
creation_date: 2021-11-04T14:00:28Z

[Term]
id: MMO:0000783
name: laparotomy
def: "A laparotomy is a surgical procedure involving a surgical incision through the abdominal wall to gain access into the abdominal cavity." [https://en.wikipedia.org/wiki/Laparotomy, https://www.merriam-webster.com]
synonym: "celiotomy" EXACT []
is_a: MMO:0000026 ! in vivo method
created_by: slaulede
creation_date: 2022-02-07T16:11:37Z

[Term]
id: MMO:0000784
name: automated serum calcium test
def: "This is the automated analysis of total calcium in blood serum, which includes free, ionized calcium and calcium bound to anions and proteins." [https://pediaa.com/what-is-the-difference-between-ionized-calcium-and-serum-calcium/]
synonym: "automated test of total calcium in serum" EXACT []
is_a: MMO:0000556 ! automated serum electrolyte analysis
created_by: slaulede
creation_date: 2022-02-22T17:39:57Z

[Term]
id: MMO:0000785
name: automated serum lipid analysis
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the physical or chemical characteristics of serum lipids, water insoluble fats and fat-like substances in the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [https://www.merriam-webster.com/, ISBN-13:978-0781733908]
is_a: MMO:0000038 ! blood lipid analysis
is_a: MMO:0000554 ! automated serum analysis
created_by: slaulede
creation_date: 2022-02-22T18:06:14Z

[Term]
id: MMO:0000786
name: automated serum total cholesterol analysis
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the total amount of cholesterol in serum, including cholesterol carried in any and all types of lipoprotein molecules." [https://www.merriam-webster.com/, ISBN-13:978-0781733908]
synonym: "automated analysis of total cholesterol in serum" EXACT []
is_a: MMO:0000785 ! automated serum lipid analysis
created_by: slaulede
creation_date: 2022-02-22T18:16:53Z

[Term]
id: MMO:0000787
name: blood aspartate aminotransferase activity assay
def: "This is a method which quantifies the enzymatic activity of glutamic-oxaloacetic transaminase enzyme, commonly known as aspartate transaminase or aspartate aminotransferase (AST), in a specified sample of blood. AST catalyzes the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid. Blood AST level is used as an enzymatic marker for liver disease or damage." [http://en.wikipedia.org/wiki/Aspartate_transaminase, VT:0000203]
synonym: "blood aspartate transaminase activity assay" EXACT []
synonym: "blood AST activity assay" EXACT []
synonym: "blood glutamic-oxaloacetic transaminase activity assay" EXACT []
synonym: "blood GOT activity assay" EXACT []
is_a: MMO:0000429 ! blood enzyme activity assay
created_by: slaulede
creation_date: 2022-02-24T08:59:26Z

[Term]
id: MMO:0000788
name: serum aspartate aminotransferase activity assay
def: "This is a method which quantifies the enzymatic activity of glutamic-oxaloacetic transaminase enzyme, commonly known as aspartate transaminase or aspartate aminotransferase (AST), in a specified sample of serum, i.e. blood plasma from which clotting factors have been removed. AST catalyzes the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid. Blood AST level is used as an enzymatic marker for liver disease or damage." [http://en.wikipedia.org/wiki/Aspartate_transaminase, ISBN-13:978-0781733908]
synonym: "serum aspartate transaminase activity assay" EXACT []
synonym: "serum AST activity assay" EXACT []
synonym: "serum glutamic-oxaloacetic transaminase activity assay" EXACT []
synonym: "serum GOT activity assay" EXACT []
is_a: MMO:0000787 ! blood aspartate aminotransferase activity assay
created_by: slaulede
creation_date: 2022-02-24T09:06:19Z

[Term]
id: MMO:0000789
name: automated serum aspartate aminotransferase activity assay
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the enzymatic activity of glutamic-oxaloacetic transaminase enzyme, commonly known as aspartate transaminase or aspartate aminotransferase (AST), in a specified sample of serum, i.e. blood plasma from which clotting factors have been removed. AST catalyzes the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid. Blood AST level is used as an enzymatic marker for liver disease or damage." [https://www.merriam-webster.com/, ISBN-13:978-0781733908]
synonym: "automated serum aspartate transaminase activity assay" EXACT []
synonym: "automated serum AST activity assay" EXACT []
synonym: "automated serum glutamic-oxaloacetic transaminase activity assay" EXACT []
synonym: "automated serum GOT activity assay" EXACT []
is_a: MMO:0000788 ! serum aspartate aminotransferase activity assay
created_by: slaulede
creation_date: 2022-02-24T09:26:32Z

[Term]
id: MMO:0000790
name: blood alanine aminotransferase activity assay
def: "This is a method which quantifies the enzymatic activity of glutamic-pyruvate transaminase enzyme, commonly known as alanine transaminase or alanine aminotransferase (ALT), enzyme in a specified sample of blood. ALT catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Serum ALT level is used as an enzymatic marker for liver disease or damage." [https://en.wikipedia.org/wiki/Alanine_transaminase, https://www.merriam-webster.com/]
synonym: "blood alanine transaminase activity assay" EXACT []
synonym: "blood ALT activity assay" EXACT []
synonym: "blood glutamic-pyruvate transaminase activity assay" EXACT []
synonym: "blood GPT activity assay" EXACT []
is_a: MMO:0000429 ! blood enzyme activity assay
created_by: slaulede
creation_date: 2022-02-24T09:44:34Z

[Term]
id: MMO:0000791
name: serum alanine aminotransferase activity assay
def: "This is a method which quantifies the enzymatic activity of glutamic-pyruvate transaminase enzyme, commonly known as alanine transaminase or alanine aminotransferase (ALT), enzyme in a specified sample of serum, i.e. blood plasma from which fibrinogen has been removed. ALT catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Serum ALT level is used as an enzymatic marker for liver disease or damage." [https://en.wikipedia.org/wiki/Alanine_transaminase, ISBN-13:978-0781733908]
synonym: "serum alanine transaminase activity assay" EXACT []
synonym: "serum ALT activity assay" EXACT []
synonym: "serum glutamic-pyruvate transaminase activity assay" EXACT []
synonym: "serum GPT activity assay" EXACT []
is_a: MMO:0000790 ! blood alanine aminotransferase activity assay
created_by: slaulede
creation_date: 2022-02-24T09:57:16Z

[Term]
id: MMO:0000792
name: automated serum alanine aminotransferase activity assay
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the enzymatic activity of glutamic-pyruvate transaminase enzyme, commonly known as alanine transaminase or alanine aminotransferase (ALT), enzyme in a specified sample of serum, i.e. blood plasma from which clotting factors have been removed. ALT catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Serum ALT level is used as an enzymatic marker for liver disease or damage." [https://en.wikipedia.org/wiki/Alanine_transaminase, https://www.merriam-webster.com/]
synonym: "automated serum alanine transaminase activity assay" EXACT []
synonym: "automated serum ALT activity assay" EXACT []
synonym: "automated serum glutamic-pyruvate transaminase activity assay" EXACT []
synonym: "automated serum GPT activity assay" EXACT []
is_a: MMO:0000791 ! serum alanine aminotransferase activity assay
created_by: slaulede
creation_date: 2022-02-24T10:05:22Z

[Term]
id: MMO:0000793
name: blood alkaline phosphatase activity assay
def: "This is a method which quantifies the enzymatic activity of alkaline phosphatase (AP) in a specified sample of blood. AP is an enzyme that catalyzes the cleavage of orthophosphate from orthophosphoric monoesters under alkaline conditions." [https://en.wikipedia.org/wiki/Alkaline_phosphatase, ISBN-13:978-0781733908]
synonym: "blood ALKP activity assay" EXACT []
synonym: "blood alk phos activity assay" EXACT []
synonym: "blood ALP activity assay" EXACT []
synonym: "blood ALPase activity assay" EXACT []
synonym: "blood basic phosphatase activity assay" EXACT []
is_a: MMO:0000429 ! blood enzyme activity assay
created_by: slaulede
creation_date: 2022-02-24T10:24:06Z

[Term]
id: MMO:0000794
name: serum alkaline phosphatase activity assay
def: "This is a method which quantifies the enzymatic activity of alkaline phosphatase (AP) in a specified sample of serum, i.e. blood plasma from which clotting factors have been removed. AP is an enzyme that catalyzes the cleavage of orthophosphate from orthophosphoric monoesters under alkaline conditions." [https://en.wikipedia.org/wiki/Alkaline_phosphatase, ISBN-13:978-0781733908]
synonym: "serum ALKP activity assay" EXACT []
synonym: "serum alk phos activity assay" EXACT []
synonym: "serum ALP activity assay" EXACT []
synonym: "serum ALPase activity assay" EXACT []
synonym: "serum basic phosphatase activity assay" EXACT []
is_a: MMO:0000793 ! blood alkaline phosphatase activity assay
created_by: slaulede
creation_date: 2022-02-24T10:45:56Z

[Term]
id: MMO:0000795
name: automated plasma phosphate test
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the amount of phosphate in blood plasma, the fluid portion of the blood remaining after cells and platelets are removed. Phosphate is an electrically charged particle that contains the mineral phosphorus. Phosphorus works together with the mineral calcium to build strong bones and teeth. Normally, the kidneys filter and remove excess phosphate from the blood." [https://medlineplus.gov/lab-tests/phosphate-in-blood/, ISBN-13:9780781733908]
synonym: "automated plasma phosphate analysis" EXACT []
xref: PMID:31125290
is_a: MMO:0000805 ! automated plasma electrolyte analysis
created_by: slaulede
creation_date: 2022-02-24T10:53:35Z

[Term]
id: MMO:0000796
name: automated serum globulin analysis
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the amount of globulins, a broad category of plasma proteins, in a specified sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [https://www.merriam-webster.com/, ISBN-13:978-0781733908]
is_a: MMO:0000346 ! automated serum protein analysis
is_a: MMO:0000798 ! serum globulin analysis
created_by: slaulede
creation_date: 2022-02-24T15:21:37Z

[Term]
id: MMO:0000797
name: blood globulin analysis
def: "This is a method to determine the amount of globulins, a broad category of plasma proteins, in a specified sample of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them." [https://www.merriam-webster.com/, ISBN-13:978-0781733908]
is_a: MMO:0000166 ! blood protein analysis
created_by: slaulede
creation_date: 2022-02-24T15:38:48Z

[Term]
id: MMO:0000798
name: serum globulin analysis
def: "This is a method to determine the amount of globulins, a broad category of plasma proteins, in a specified sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed." [https://www.merriam-webster.com/, ISBN-13:978-0781733908]
is_a: MMO:0000797 ! blood globulin analysis
created_by: slaulede
creation_date: 2022-02-24T15:43:16Z

[Term]
id: MMO:0000799
name: blood creatine kinase activity assay
def: "This is a method which quantifies the enzymatic activity of creatine kinase (CK) in a specified sample of blood. CK catalyses the reversible transfer of phosphate between ATP and various phosphogens such as creatine phosphate. Blood CK level is used as an enzymatic marker for myocardial infarction, rhabdomyolysis and acute renal failure." [http://en.wikipedia.org/wiki/Creatine_kinase, ISBN-13:978-0781733908]
synonym: "blood CK activity assay" EXACT []
synonym: "blood CPK activity assay" EXACT []
synonym: "blood creatine phosphokinase activity assay" EXACT []
synonym: "blood phosphocreatine kinase activity assay" EXACT []
is_a: MMO:0000429 ! blood enzyme activity assay
created_by: slaulede
creation_date: 2022-02-24T16:36:18Z

[Term]
id: MMO:0000800
name: serum creatine kinase activity assay
def: "This is a method which quantifies the enzymatic activity of creatine kinase (CK) in a specified sample of serum, i.e. blood plasma from which clotting factors have been removed. CK catalyses the reversible transfer of phosphate between ATP and various phosphogens such as creatine phosphate. Serum CK level is used as an enzymatic marker for myocardial infarction, rhabdomyolysis and acute renal failure." [http://en.wikipedia.org/wiki/Creatine_kinase, ISBN-13:978-0781733908]
synonym: "serum CK activity assay" EXACT []
synonym: "serum CPK activity assay" EXACT []
synonym: "serum creatine phosphokinase activity assay" EXACT []
synonym: "serum phosphocreatine kinase activity assay" EXACT []
is_a: MMO:0000799 ! blood creatine kinase activity assay
created_by: slaulede
creation_date: 2022-02-24T16:48:26Z

[Term]
id: MMO:0000801
name: automated serum creatine kinase activity assay
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the enzymatic activity of creatine kinase (CK) in a specified sample of serum, i.e. blood plasma from which clotting factors have been removed. CK catalyses the reversible transfer of phosphate between ATP and various phosphogens such as creatine phosphate. Serum CK level is used as an enzymatic marker for myocardial infarction, rhabdomyolysis and acute renal failure." [http://en.wikipedia.org/wiki/Creatine_kinase, ISBN-13:978-0781733908]
synonym: "automated serum CK activity assay" EXACT []
synonym: "automated serum CPK activity assay" EXACT []
synonym: "automated serum creatine phosphokinase activity assay" EXACT []
synonym: "automated serum phosphocreatine kinase activity assay" EXACT []
is_a: MMO:0000800 ! serum creatine kinase activity assay
created_by: slaulede
creation_date: 2022-02-24T16:54:40Z

[Term]
id: MMO:0000802
name: automated serum alkaline phosphatase activity assay
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the enzymatic activity of alkaline phosphatase (AP) in a specified sample of serum, i.e. blood plasma from which clotting factors have been removed. AP is an enzyme that catalyzes the cleavage of orthophosphate from orthophosphoric monoesters under alkaline conditions." [https://en.wikipedia.org/wiki/Alkaline_phosphatase, ISBN-13:978-0781733908]
synonym: "automated serum ALKP activity assay" EXACT []
synonym: "automated serum alk phos activity assay" EXACT []
synonym: "automated serum ALP activity assay" EXACT []
synonym: "automated serum ALPase activity assay" EXACT []
synonym: "automated serum basic phosphatase activity assay" EXACT []
is_a: MMO:0000794 ! serum alkaline phosphatase activity assay
created_by: slaulede
creation_date: 2022-02-24T17:09:24Z

[Term]
id: MMO:0000803
name: automated serum urea analysis
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the amount, level or concentration of urea, the chief nitrogenous end product of protein metabolism, in serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which clotting factors have been removed." [https://en.wikipedia.org/wiki/Blood_urea_nitrogen, ISBN-13:978-0781733908]
is_a: MMO:0000273 ! serum urea analysis
is_a: MMO:0000554 ! automated serum analysis
created_by: slaulede
creation_date: 2022-02-24T17:43:28Z

[Term]
id: MMO:0000804
name: automated plasma calcium test
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the total calcium in blood plasma, which includes free, ionized calcium and calcium bound to anions and proteins." [https://www.donatingplasma.org/donation/what-is-plasma, ISBN-13:9780781733908]
synonym: "automated plasma calcium analysis" EXACT []
xref: PMID:32084371
is_a: MMO:0000805 ! automated plasma electrolyte analysis
created_by: slaulede
creation_date: 2022-03-04T18:01:22Z

[Term]
id: MMO:0000805
name: automated plasma electrolyte analysis
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure one or more electrolytes, substances which dissociate into ions, in blood plasma, the fluid portion of the blood remaining after cells and platelets are removed." [https://www.donatingplasma.org/donation/what-is-plasma, ISBN-13:9780781733908]
is_a: MMO:0000037 ! automated blood electrolyte analysis
created_by: slaulede
creation_date: 2022-03-04T18:04:17Z

[Term]
id: MMO:0000806
name: automated plasma globulin analysis
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the amount of globulins, a broad category of plasma proteins, in a specified sample of plasma, the fluid portion of the blood remaining after cells and platelets are removed." [https://www.merriam-webster.com, ISBN-13:9780781733908]
synonym: "automated plasma globulin test" EXACT []
xref: PMID:32084371
is_a: MMO:0000352 ! automated plasma protein analysis
created_by: slaulede
creation_date: 2022-03-04T18:21:48Z

[Term]
id: MMO:0000807
name: plasma alanine aminotransferase activity assay
def: "This is a method which quantifies the enzymatic activity of glutamic-pyruvate transaminase enzyme, commonly known as alanine transaminase or alanine aminotransferase (ALT), enzyme in a specified sample of blood plasma. ALT catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Serum ALT level is used as an enzymatic marker for liver disease or damage." [https://www.merriam-webster.com, ISBN-13:9780781733908]
synonym: "plasma alanine aminotransferase activity test" EXACT []
synonym: "plasma alanine transaminase activity assay" EXACT []
synonym: "plasma ALT activity assay" EXACT []
synonym: "plasma glutamic-pyruvate transaminase activity assay" EXACT []
synonym: "plasma GPT activity assay" EXACT []
is_a: MMO:0000790 ! blood alanine aminotransferase activity assay
created_by: slaulede
creation_date: 2022-03-04T18:28:28Z

[Term]
id: MMO:0000808
name: automated plasma alanine aminotransferase activity assay
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the enzymatic activity of glutamic-pyruvate transaminase enzyme, commonly known as alanine transaminase or alanine aminotransferase (ALT), enzyme in a specified sample of plasma, the fluid portion of the blood remaining after cells and platelets are removed. ALT catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Serum ALT level is used as an enzymatic marker for liver disease or damage." [https://www.merriam-webster.com, ISBN-13:9780781733908]
synonym: "automated plasma alanine aminotransferase activity test" EXACT []
synonym: "automated plasma alanine transaminase activity assay" EXACT []
synonym: "automated plasma ALT activity assay" EXACT []
synonym: "automated plasma glutamic-pyruvate transaminase activity assay" EXACT []
synonym: "automated plasma GPT activity assay" EXACT []
is_a: MMO:0000807 ! plasma alanine aminotransferase activity assay
created_by: slaulede
creation_date: 2022-03-04T18:32:46Z

[Term]
id: MMO:0000809
name: blood leptin analysis
def: "Any method by which the level or concentration in a sample of blood of leptin is measured. Leptin is secreted by white adipocytes and enterocytes. It plays a major role in the regulation of energy homeostasis" [https://en.wikipedia.org/wiki/Leptin, RGD:69123]
synonym: "blood LEP analysis" EXACT []
is_a: MMO:0000311 ! blood hormone analysis
created_by: slaulede
creation_date: 2022-03-07T17:49:06Z

[Term]
id: MMO:0000810
name: automated plasma magnesium test
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the amount of magnesium in blood plasma, the fluid portion of the blood remaining after cells and platelets are removed. Magnesium is a cofactor in more than 300 enzyme systems that regulate diverse biochemical reactions in the body." [https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/, https://www.merriam-webster.com]
xref: PMID:32084371
is_a: MMO:0000805 ! automated plasma electrolyte analysis
created_by: slaulede
creation_date: 2022-03-08T11:19:58Z

[Term]
id: MMO:0000811
name: plasma aspartate aminotransferase activity assay
def: "This is a method which quantifies the enzymatic activity of glutamic-oxaloacetic transaminase enzyme, commonly known as aspartate transaminase or aspartate aminotransferase (AST), in a specified sample of plasma, i.e. blood from which cells and platelets have been removed. AST catalyzes the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid. Blood AST level is used as an enzymatic marker for liver disease or damage." [http://en.wikipedia.org/wiki/Aspartate_transaminase, ISBN-13:978-0781733908]
synonym: "plasma aspartate transaminase activity assay" EXACT []
synonym: "plasma AST activity assay" EXACT []
synonym: "plasma glutamic-oxaloacetic transaminase activity assay" EXACT []
synonym: "plasma GOT activity assay" EXACT []
is_a: MMO:0000787 ! blood aspartate aminotransferase activity assay
created_by: slaulede
creation_date: 2022-03-08T15:53:57Z

[Term]
id: MMO:0000812
name: automated plasma aspartate aminotransferase activity assay
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the enzymatic activity of glutamic-oxaloacetic transaminase enzyme, commonly known as aspartate transaminase or aspartate aminotransferase (AST), in a specified sample of plasma, i.e. blood from which cells and platelets have been removed. AST catalyzes the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid. Blood AST level is used as an enzymatic marker for liver disease or damage." [http://en.wikipedia.org/wiki/Aspartate_transaminase, ISBN-13:978-0781733908]
synonym: "automated plasma aspartate transaminase activity assay" EXACT []
synonym: "automated plasma AST activity assay" EXACT []
synonym: "automated plasma glutamic-oxaloacetic transaminase activity assay" EXACT []
synonym: "automated plasma GOT activity assay" EXACT []
is_a: MMO:0000811 ! plasma aspartate aminotransferase activity assay
created_by: slaulede
creation_date: 2022-03-08T15:58:07Z

[Term]
id: MMO:0000813
name: plasma alkaline phosphatase activity assay
def: "This is a method which quantifies the enzymatic activity of alkaline phosphatase (AP) in a specified sample of plasma, i.e. blood from which cells and platelets have been removed. AP is an enzyme that catalyzes the cleavage of orthophosphate from orthophosphoric monoesters under alkaline conditions." [https://en.wikipedia.org/wiki/Alkaline_phosphatase, ISBN-13:978-0781733908]
synonym: "plasma ALKP activity assay" EXACT []
synonym: "plasma alk phos activity assay" EXACT []
synonym: "plasma ALP activity assay" EXACT []
synonym: "plasma ALPase activity assay" EXACT []
synonym: "plasma basic phosphatase activity assay" EXACT []
is_a: MMO:0000793 ! blood alkaline phosphatase activity assay
created_by: slaulede
creation_date: 2022-03-08T16:40:57Z

[Term]
id: MMO:0000814
name: plasma urea analysis
def: "An assay which measures the amount, level or concentration of urea, the chief nitrogenous endproduct of protein metabolism, in plasma, i.e. blood from which cells and platelets have been removed." [https://www.merriam-webster.com, ISBN-13:978-0781733908]
xref: PMID:32084371
is_a: MMO:0000272 ! blood urea analysis
created_by: slaulede
creation_date: 2022-03-08T16:48:55Z

[Term]
id: MMO:0000815
name: automated plasma alkaline phosphatase activity assay
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the enzymatic activity of alkaline phosphatase (AP) in a specified sample of plasma, i.e. blood from which cells and platelets have been removed. AP is an enzyme that catalyzes the cleavage of orthophosphate from orthophosphoric monoesters under alkaline conditions." [https://en.wikipedia.org/wiki/Alkaline_phosphatase, ISBN-13:978-0781733908]
synonym: "automated plasma ALKP activity assay" EXACT []
synonym: "automated plasma alk phos activity assay" EXACT []
synonym: "automated plasma ALP activity assay" EXACT []
synonym: "automated plasma ALPase activity assay" EXACT []
synonym: "automated plasma basic phosphatase activity assay" EXACT []
is_a: MMO:0000813 ! plasma alkaline phosphatase activity assay
created_by: slaulede
creation_date: 2022-03-08T16:52:09Z

[Term]
id: MMO:0000816
name: plasma creatine kinase activity assay
def: "This is a method which quantifies the enzymatic activity of creatine kinase (CK) in a specified sample of plasma, i.e. blood from which cells and platelets have been removed. CK catalyses the reversible transfer of phosphate between ATP and various phosphogens such as creatine phosphate." [http://en.wikipedia.org/wiki/Creatine_kinase, ISBN-13:978-0781733908]
synonym: "plasma CK activity assay" EXACT []
synonym: "plasma CPK activity assay" EXACT []
synonym: "plasma creatine phosphokinase activity assay" EXACT []
synonym: "plasma phosphocreatine kinase activity assay" EXACT []
is_a: MMO:0000799 ! blood creatine kinase activity assay
created_by: slaulede
creation_date: 2022-03-11T14:13:07Z

[Term]
id: MMO:0000817
name: automated plasma creatine kinase activity assay
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the enzymatic activity of creatine kinase (CK) in a specified sample of plasma, i.e. blood from which cells and platelets have been removed. CK catalyses the reversible transfer of phosphate between ATP and various phosphogens such as creatine phosphate." [http://en.wikipedia.org/wiki/Creatine_kinase, ISBN-13:978-0781733908]
synonym: "automated plasma CK activity assay" EXACT []
synonym: "automated plasma CPK activity assay" EXACT []
synonym: "automated plasma creatine phosphokinase activity assay" EXACT []
synonym: "automated plasma phosphocreatine kinase activity assay" EXACT []
is_a: MMO:0000816 ! plasma creatine kinase activity assay
created_by: slaulede
creation_date: 2022-03-11T14:26:45Z

[Term]
id: MMO:0000818
name: automated plasma urea analysis
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the amount, level or concentration of urea, the chief nitrogenous end product of protein metabolism, in plasma, the clear liquid that separates from blood after it has clotted completely, i.e. blood from which cells and platelets have been removed." [https://www.merriam-webster.com, ISBN-13:978-0781733908]
xref: PMID:32084371
is_a: MMO:0000553 ! automated plasma analysis
is_a: MMO:0000814 ! plasma urea analysis
created_by: slaulede
creation_date: 2022-03-11T14:54:57Z

[Term]
id: MMO:0000819
name: automated plasma bicarbonate test
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the amount of bicarbonate, an anion of carbonic acid in which only one of the hydrogen atoms has been removed, in plasma, i.e. blood from which cells and platelets have been removed." [https://www.merriam-webster.com, ISBN-13:978-0781733908]
xref: PMID:32084371
is_a: MMO:0000805 ! automated plasma electrolyte analysis
created_by: slaulede
creation_date: 2022-03-11T15:33:57Z

[Term]
id: MMO:0000820
name: plasma leptin analysis
def: "Any method by which the level or concentration of leptin in a sample of plasma is measured. Leptin is secreted by white adipocytes and enterocytes. It plays a major role in the regulation of energy homeostasis" [https://en.wikipedia.org/wiki/Leptin, RGD:69123]
synonym: "plasma LEP analysis" EXACT []
is_a: MMO:0000809 ! blood leptin analysis
created_by: slaulede
creation_date: 2022-03-11T15:46:22Z

[Term]
id: MMO:0000821
name: automated plasma chloride test
def: "This is an automated analysis to determine the level of chloride ions in plasma, the fluid portion of the blood remaining after cells and platelets are removed." [https://www.donatingplasma.org/donation/what-is-plasma, ISBN-13:978-0781733908]
is_a: MMO:0000805 ! automated plasma electrolyte analysis
created_by: slaulede
creation_date: 2022-03-17T16:28:53Z

[Term]
id: MMO:0000822
name: automated plasma potassium test
def: "This is an automated analysis to determine the level of potassium ions in plasma, the fluid portion of the blood remaining after cells and platelets are removed." [https://www.donatingplasma.org/donation/what-is-plasma, ISBN-13:978-0781733908]
is_a: MMO:0000805 ! automated plasma electrolyte analysis
created_by: slaulede
creation_date: 2022-03-17T16:35:05Z

[Term]
id: MMO:0000823
name: automated plasma sodium test
def: "This is an automated analysis to determine the level of sodium ions in plasma, the fluid portion of the blood remaining after cells and platelets are removed." [https://www.donatingplasma.org/donation/what-is-plasma, ISBN-13:978-0781733908]
is_a: MMO:0000805 ! automated plasma electrolyte analysis
created_by: slaulede
creation_date: 2022-03-17T16:39:55Z

[Term]
id: MMO:0000824
name: automated plasma total bilirubin analysis
def: "This a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the entire amount of total (direct and indirect) bilirubin in a specified volume of plasma, the fluid portion of the blood remaining after cells and platelets are removed." [https://en.wikipedia.org/wiki/Bilirubin, ISBN-13:978-0781733908]
xref: PMID:31125290
is_a: MMO:0000553 ! automated plasma analysis
is_a: MMO:0000826 ! plasma total bilirubin analysis
created_by: slaulede
creation_date: 2022-03-24T12:18:16Z

[Term]
id: MMO:0000825
name: blood total bilirubin analysis
def: "This is any assay which measures the amount, level or concentration of total (direct and indirect) bilirubin in whole blood." [https://en.wikipedia.org/wiki/Bilirubin, ISBN-13:978-0781733908]
xref: PMID:31125290
is_a: MMO:0000030 ! ex vivo blood analysis
created_by: slaulede
creation_date: 2022-03-24T12:37:02Z

[Term]
id: MMO:0000826
name: plasma total bilirubin analysis
def: "This is an assay which measures the amount, level or concentration of total (direct and indirect) bilirubin in a specified volume of plasma, the fluid portion of the blood remaining after cells and platelets are removed." [https://en.wikipedia.org/wiki/Bilirubin, ISBN-13:978-0781733908]
xref: PMID:31125290
is_a: MMO:0000825 ! blood total bilirubin analysis
created_by: slaulede
creation_date: 2022-03-24T12:55:25Z

[Term]
id: MMO:0000827
name: serum total bilirubin analysis
def: "This is an assay which measures the amount, level or concentration of total (direct and indirect) bilirubin in a specified volume of serum, i.e. blood from which cells, platelets and clotting factors have been removed have been removed by clot formation." [https://en.wikipedia.org/wiki/Bilirubin, ISBN-13:978-0781733908]
xref: PMID:31125290
is_a: MMO:0000825 ! blood total bilirubin analysis
created_by: slaulede
creation_date: 2022-03-24T13:05:23Z

[Term]
id: MMO:0000828
name: blood gamma-glutamyltransferase activity assay
def: "This is a method which quantifies the enzymatic activity of gamma-glutamyltransferase (GGT) in a specified sample of blood. GGT catalyzes the transfer of the gamma-glutamyl moiety of glutathione to an acceptor such as amino acid, a peptide or water. Blood GGT level is used as an enzymatic marker for liver disease or damage." [http://en.wikipedia.org/wiki/Gamma-glutamyl_transpeptidase, ISBN-13:978-0781733908]
synonym: "blood gamma-glutamyl transpeptidase activity assay" EXACT []
synonym: "blood GGT activity assay" EXACT []
synonym: "blood GGTP activity assay" EXACT []
xref: PMID:31125290
is_a: MMO:0000429 ! blood enzyme activity assay
created_by: slaulede
creation_date: 2022-03-24T16:35:53Z

[Term]
id: MMO:0000829
name: plasma gamma-glutamyltransferase activity assay
def: "This is a method which quantifies the enzymatic activity of gamma-glutamyltransferase (GGT) in a specified sample of plasma, the fluid portion of the blood remaining after cells and platelets are removed. GGT catalyzes the transfer of the gamma-glutamyl moiety of glutathione to an acceptor such as amino acid, a peptide or water. Blood GGT level is used as an enzymatic marker for liver disease or damage." [http://en.wikipedia.org/wiki/Gamma-glutamyl_transpeptidase, ISBN-13:978-0781733908]
synonym: "plasma gamma-glutamyl transpeptidase activity assay" EXACT []
synonym: "plasma GGT activity assay" EXACT []
synonym: "plasma GGTP activity assay" EXACT []
xref: PMID:31125290
is_a: MMO:0000828 ! blood gamma-glutamyltransferase activity assay
created_by: slaulede
creation_date: 2022-03-24T16:42:35Z

[Term]
id: MMO:0000830
name: serum gamma-glutamyltransferase activity assay
def: "This is a method which quantifies the enzymatic activity of gamma-glutamyltransferase (GGT) in a specified sample of serum, i.e. blood plasma from which cells, platelets, and clotting factors have been removed. GGT catalyzes the transfer of the gamma-glutamyl moiety of glutathione to an acceptor such as amino acid, a peptide or water. Blood GGT level is used as an enzymatic marker for liver disease or damage." [http://en.wikipedia.org/wiki/Gamma-glutamyl_transpeptidase, ISBN-13:978-0781733908]
synonym: "serum gamma-glutamyl transpeptidase activity assay" EXACT []
synonym: "serum GGT activity assay" EXACT []
synonym: "serum GGTP activity assay" EXACT []
xref: PMID:31125290
is_a: MMO:0000828 ! blood gamma-glutamyltransferase activity assay
created_by: slaulede
creation_date: 2022-03-24T16:46:53Z

[Term]
id: MMO:0000831
name: automated plasma gamma-glutamyltransferase activity assay
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the enzymatic activity of gamma-glutamyltransferase (GGT) in a specified sample of plasma, the fluid portion of the blood remaining after cells and platelets are removed. GGT catalyzes the transfer of the gamma-glutamyl moiety of glutathione to an acceptor such as amino acid, a peptide or water. Blood GGT level is used as an enzymatic marker for liver disease or damage." [http://en.wikipedia.org/wiki/Gamma-glutamyl_transpeptidase, ISBN-13:978-0781733908]
synonym: "plasma gamma-glutamyl transpeptidase activity assay" EXACT []
synonym: "plasma GGT activity assay" EXACT []
synonym: "plasma GGTP activity assay" EXACT []
xref: PMID:31125290
is_a: MMO:0000829 ! plasma gamma-glutamyltransferase activity assay
created_by: slaulede
creation_date: 2022-03-24T16:57:41Z

[Term]
id: MMO:0000832
name: automated serum low-density lipoprotein-cholesterol analysis
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure cholesterol carried in low-density lipoprotein (LDL) particles in serum, the clear liquid that separates from blood after it has clotted completely." [https://www.merriam-webster.com/, ISBN-13:978-0781733908]
synonym: "automated serum LDL-cholesterol test" EXACT []
is_a: MMO:0000134 ! serum low-density lipoprotein-cholesterol measurement test
is_a: MMO:0000346 ! automated serum protein analysis
created_by: slaulede
creation_date: 2022-04-04T12:24:02Z

[Term]
id: MMO:0000833
name: automated serum high-density lipoprotein-cholesterol measurement test
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure cholesterol carried in high-density lipoprotein (LDL) particles in serum, the clear liquid that separates from blood after it has clotted completely," [https://www.merriam-webster.com/, ISBN-13:978-0781733908]
synonym: "automated serum HDL-cholesterol test" EXACT []
is_a: MMO:0000133 ! serum high-density lipoprotein-cholesterol measurement test
is_a: MMO:0000346 ! automated serum protein analysis
created_by: slaulede
creation_date: 2022-04-04T13:46:04Z

[Term]
id: MMO:0000834
name: automated plasma high-density lipoprotein-cholesterol measurement test
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure cholesterol carried in high-density lipoprotein (LDL) particles in plasma, the fluid portion of the blood in which the particulate components are suspended." [https://www.merriam-webster.com/, ISBN-13:978-0781733908]
synonym: "automated plasma HDL-cholesterol test" EXACT []
is_a: MMO:0000282 ! plasma high-density lipoprotein-cholesterol measurement test
is_a: MMO:0000553 ! automated plasma analysis
created_by: slaulede
creation_date: 2022-04-04T13:52:27Z

[Term]
id: MMO:0000835
name: automated blood glucose analysis
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the entire amount of glucose, the end product of carbohydrate metabolism, in the blood." [https://www.merriam-webster.com/, ISBN-13:978-0781733908]
is_a: MMO:0000112 ! blood glucose analysis
created_by: slaulede
creation_date: 2022-04-07T14:51:17Z

[Term]
id: MMO:0000836
name: automated serum glucose analysis
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the entire amount of glucose in serum, the clear liquid that separates from blood after cells, platelets, and clotting factors have been removed." [https://www.merriam-webster.com/, ISBN-13:978-0781733908]
is_a: MMO:0000316 ! serum glucose analysis
is_a: MMO:0000835 ! automated blood glucose analysis
created_by: slaulede
creation_date: 2022-04-07T14:55:44Z

[Term]
id: MMO:0000837
name: automated plasma glucose analysis
alt_id: MMO:0000735
def: "Method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the entire amount of glucose in plasma, the clear liquid that separates from blood after cells and platelets have been removed." [https://www.merriam-webster.com/, ISBN-13:978-0781733908]
is_a: MMO:0000315 ! plasma glucose analysis
is_a: MMO:0000553 ! automated plasma analysis
is_a: MMO:0000835 ! automated blood glucose analysis
created_by: slaulede
creation_date: 2022-04-07T15:00:29Z

[Term]
id: MMO:0000838
name: automated blood urea nitrogen analysis
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the amount of nitrogen present in the blood in the form of urea, the chief nitrogenous end product of protein metabolism. Urea is formed in the liver from amino acids and from ammonia compounds and is found in urine, blood, and lymph." [https://www.merriam-webster.com/, ISBN-13:978-0781733908]
synonym: "automated BUN test" EXACT []
is_a: MMO:0000179 ! automated blood analysis
is_a: MMO:0000253 ! blood urea nitrogen analysis
created_by: slaulede
creation_date: 2022-04-07T15:05:45Z

[Term]
id: MMO:0000839
name: automated serum urea nitrogen analysis
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the amount of nitrogen present in serum, the clear liquid that separates from blood after it has clotted completely. Urea is the chief nitrogenous end product of protein metabolism and is formed in the liver from amino acids and from ammonia compounds and is found in urine, blood, and lymph." [https://www.merriam-webster.com/, ISBN-13:978-0781733908]
is_a: MMO:0000803 ! automated serum urea analysis
is_a: MMO:0000838 ! automated blood urea nitrogen analysis
created_by: slaulede
creation_date: 2022-04-07T15:08:36Z

[Term]
id: MMO:0000840
name: automated plasma urea nitrogen analysis
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the amount of nitrogen present in plasma, the clear liquid that separates from blood after cells and platelets have been removed. Urea is the chief nitrogenous end product of protein metabolism and is formed in the liver from amino acids and from ammonia compounds and is found in urine, blood, and lymph." [https://www.merriam-webster.com/, ISBN-13:978-0781733908]
is_a: MMO:0000818 ! automated plasma urea analysis
created_by: slaulede
creation_date: 2022-04-07T15:11:21Z

[Term]
id: MMO:0000841
name: automated serum triglyceride analysis
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure triglyceride, the naturally occurring ester of three fatty acids and glycerol that is the chief constituent of fat, in serum. Serum is the clear liquid that separates from blood when cells, platelets, and clotting factors have been removed." [https://www.merriam-webster.com/, ISBN-13:978-0781733908]
is_a: MMO:0000136 ! serum triglyceride analysis
is_a: MMO:0000785 ! automated serum lipid analysis
created_by: slaulede
creation_date: 2022-04-07T15:23:18Z

[Term]
id: MMO:0000842
name: automated plasma lipid analysis
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure plasma lipids, water insoluble fats and fat-like substances in the clear liquid that remains after cells and platelets have been removed from blood." [https://www.merriam-webster.com/, ISBN-13:978-0781733908]
is_a: MMO:0000038 ! blood lipid analysis
is_a: MMO:0000553 ! automated plasma analysis
created_by: slaulede
creation_date: 2022-04-07T15:30:11Z

[Term]
id: MMO:0000843
name: automated serum total bilirubin analysis
def: "This a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the entire amount of total (direct and indirect) bilirubin in a specified volume of serum, the fluid portion of the blood remaining after cells,platelets, and clotting factors are removed." [https://en.wikipedia.org/wiki/Bilirubin, ISBN-13:978-0781733908]
xref: PMID:33483609
is_a: MMO:0000554 ! automated serum analysis
is_a: MMO:0000827 ! serum total bilirubin analysis
created_by: slaulede
creation_date: 2022-04-08T13:20:31Z

[Term]
id: MMO:0000844
name: free radical elective evaluator photometry
def: "This is the application of photometry (measurement of transmittance (a linear scale from 0-100%) or absorbance (a logarithmic scale from zero to infinity) of particular wavelengths of light by the use of filters) to the assessment of oxidative stress by measuring the level of free radicals (unstable atoms that can damage cells)." [http://www.diacron.com/en/content/strumentazione-free, https://www.medicalnewstoday.com/articles/318652]
synonym: "FREE photometry" EXACT []
xref: PMID:25189624
is_a: MMO:0000704 ! photometry
created_by: slaulede
creation_date: 2022-05-06T18:43:52Z

[Term]
id: MMO:0000845
name: affinity chromatography
def: "Affinity chromatography is a type of gel filtration chromatography which separates proteins on the basis of a reversible interaction between a protein (or group of proteins) and a specific ligand coupled to a chromatography matrix. With such high selectivity and hence high resolution for the protein(s) of interest, purification levels in the order of several thousand-fold with high recovery of active material are achievable. Samples are concentrated during binding and the target protein(s) is collected in a purified, concentrated form. Examples include antibody/antigen, enzyme/substrate, and enzyme/inhibitor interactions." [https://www.bio-rad.com/en-us/applications-technologies/introduction-affinity-chromatography?ID=MWHAVG4VY, https://www.merriam-webster.com/, https://www.sigmaaldrich.com/US/en/technical-documents/protocol/protein-biology/protein-purification/affinity-chromatography-in-a-purification-strategy?gclid=CjwKCAjwyryUBhBSEiwAGN5OCDg0lfZARkdeWumvPKwkZLgKZSXVEVXjjZYu-CRDA3UgireEjA9BrBoCmygQAvD_BwE]
synonym: "AC" EXACT []
xref: PMID:15780096
is_a: MMO:0000404 ! liquid column chromatography
created_by: slaulede
creation_date: 2022-05-26T15:41:19Z

[Term]
id: MMO:0000846
name: blood glucose test strip read by optical glucometer
def: "This is an automated device that calculates glucose levels in blood from a small sample (~5 ul) on an optical test strip. The glucose-derived electrons from the sample effect a change in the color of an indicating dye so a glucose level may be automatically calculated." [https://knowledge.electrochem.org/encycl/art-g01-glucose.htm]
xref: https://knowledge.electrochem.org/encycl/art-g01-glucose.htm
is_a: MMO:0000190 ! machine read blood glucose test strip
created_by: slaulede
creation_date: 2022-05-31T16:24:49Z

[Term]
id: MMO:0000847
name: electrochemiluminescence immunoassay
def: "This assay is a quantitative method for measurement of antigen or antibody based on the change in electrochemiluminescence (ECL) signal before and after immunoreaction." [https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/electrochemiluminescence]
synonym: "ECLIA" EXACT []
is_a: MMO:0000098 ! immunoassay
created_by: slaulede
creation_date: 2022-07-21T16:17:37Z

[Term]
id: MMO:0000848
name: automated urine creatinine analysis
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the level of creatinine, the catabolic product of creatine, an organic acid that assists the body in producing muscle contractions, in urine." [https://www.merriam-webster.com/, ISBN-13:978-0781733908]
is_a: MMO:0000177 ! automated urine analysis
is_a: MMO:0000275 ! urine creatinine analysis
created_by: slaulede
creation_date: 2022-07-29T12:55:53Z

[Term]
id: MMO:0000849
name: automated urine potassium analysis
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to assess the amount, proportions or properties of potassium in urine, the fluid waste product excreted by the kidneys." [https://www.merriam-webster.com/, ISBN-13:978-0781733908]
is_a: MMO:0000177 ! automated urine analysis
is_a: MMO:0000435 ! urine potassium analysis
created_by: slaulede
creation_date: 2022-07-29T13:26:10Z

[Term]
id: MMO:0000850
name: automated urine urea analysis
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to assess the amount, proportions or properties of urea in urine, the fluid waste product excreted by the kidneys." [https://www.merriam-webster.com/, ISBN-13:978-0781733908]
is_a: MMO:0000177 ! automated urine analysis
is_a: MMO:0000676 ! urine urea analysis
created_by: slaulede
creation_date: 2022-07-29T13:34:12Z

[Term]
id: MMO:0000851
name: automated urine phosphate analysis
def: "This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to assess the amount, proportions or properties of phosphate in urine, the fluid waste product excreted by the kidneys." [https://www.merriam-webster.com/, ISBN-13:978-0781733908]
is_a: MMO:0000177 ! automated urine analysis
created_by: slaulede
creation_date: 2022-07-29T14:46:52Z

[Term]
id: MMO:0000852
name: calorimetry
def: "This method is the process of measuring the amount of heat released or absorbed during a chemical reaction. By knowing the change in heat, it can be determined whether or not a reaction is exothermic (releases heat) or endothermic (absorbs heat)." [https://chem.libretexts.org/Bookshelves/Physical_and_Theoretical_Chemistry_Textbook_Maps/Supplemental_Modules_(Physical_and_Theoretical_Chemistry)/Thermodynamics/Calorimetry, https://en.wikipedia.org/wiki/Calorimetry]
is_a: MMO:0000027 ! ex vivo method
created_by: slaulede
creation_date: 2023-08-10T14:06:29Z

[Term]
id: MMO:0000853
name: constant volume calorimetry
def: "This method is used to measure the amount of heat released or absorbed during a chemical reaction while holding volume constant and resisting large amounts of pressure. A specialized instrument called a bomb calorimeter is necessary to perform this method." [https://chem.libretexts.org/Bookshelves/Physical_and_Theoretical_Chemistry_Textbook_Maps/Supplemental_Modules_(Physical_and_Theoretical_Chemistry)/Thermodynamics/Calorimetry/Constant_Volume_Calorimetry, PMID:28500600]
synonym: "bomb calorimetry" EXACT []
is_a: MMO:0000852 ! calorimetry
created_by: slaulede
creation_date: 2023-08-10T14:24:02Z

[Term]
id: MMO:0000854
name: time-domain nuclear magnetic resonance
def: "This method is a non-invasive examination of the body by means of nuclear magnetic resonance (NMR) spectroscopy. TD-NMR provides analysis of fat tissue, lean tissue and free fluid by the same physical selection rules that give rise to contrast in magnetic resonance imaging (MRI)." [https://www.bruker.com/ru/products-and-solutions/mr/nmr-epr-td-nmr-industrial-solutions/minispec-lf-series.html]
synonym: "TD-NMR" EXACT []
xref: PMID:37191987
is_a: MMO:0000709 ! nuclear magnetic resonance spectroscopy
created_by: slaulede
creation_date: 2023-08-11T16:50:57Z

[Term]
id: MMO:0000855
name: metabolic cage urine mass measurement method
def: "This is a method which utilizes a metabolic cage, a housing unit constructed for the separate collection of liquid and solid waste, to determine the mass of a sample of urine, the fluid waste product excreted by the kidneys." [http://www.pharmacelsus.de/metabolic_cage/]
synonym: "metabolic cage urine weight measurement method" RELATED []
xref: PMID:37191987
is_a: MMO:0000856 ! urine mass measurement method
created_by: slaulede
creation_date: 2023-08-21T13:57:07Z

[Term]
id: MMO:0000856
name: urine mass measurement method
def: "This is any method by which the mass of a sample of urine, the fluid waste product excreted by the kidneys, is determined." [ISBN:978-1455756438]
synonym: "urine mass measurement method" RELATED []
xref: PMID:37191987
is_a: MMO:0000147 ! urine analysis
created_by: slaulede
creation_date: 2023-08-21T14:02:11Z

[Term]
id: MMO:0000857
name: ex vivo solid waste analysis
def: "This is any method to determine the nature, properties, or composition of solid biological waste, that is a solid waste produced by a living organism, after that waste has been removed or defecated from the body." [https://www.merriam-webster.com/, ISBN:978-1455756438]
synonym: "ex vivo excrement analysis" EXACT []
synonym: "ex vivo fecal analysis" EXACT []
xref: PMID:37191987
is_a: MMO:0000027 ! ex vivo method
created_by: slaulede
creation_date: 2023-08-21T14:21:48Z

[Term]
id: MMO:0000858
name: metabolic cage feces mass measurement method
def: "This is a method which utilizes a metabolic cage, a housing unit constructed for the separate collection and measurement of liquid and solid waste, to determine the mass of a sample of feces, the bodily waste discharged through the anus." [https://www.merriam-webster.com/]
synonym: "metabolic cage feces weight measurement method" RELATED []
synonym: "metabolic cage solid waste mass measurement method" EXACT []
xref: PMID:37191987
is_a: MMO:0000857 ! ex vivo solid waste analysis
created_by: slaulede
creation_date: 2023-08-21T16:27:19Z

[Term]
id: MMO:0000859
name: metabolic cage food consumption measurement method
def: "This is a method which utilizes a metabolic cage, a housing unit constructed for the separate collection of liquid and solid waste, to determine the amount of solid or semi-solid food consumed during a fixed period of time." [https://phenome.jax.org/, https://www.merriam-webster.com/]
synonym: "metabolic cage food intake measurement method" EXACT []
synonym: "PMID:37191987" EXACT []
is_a: MMO:0000620 ! food intake measuring method
created_by: slaulede
creation_date: 2023-08-21T16:46:18Z

[Term]
id: MMO:0000860
name: metabolic cage drink measurement method (MMO:0000697)
def: "This is a method which utilizes a metabolic cage, a housing unit constructed for the separate collection of liquid and solid waste, to determine the amount of liquid consumed during a fixed time period." [https://www.merriam-webster.com/, ISBN:978-1455756438]
xref: PMID:37191987
is_a: MMO:0000619 ! drink intake measuring method
created_by: slaulede
creation_date: 2023-08-21T16:56:45Z

[Term]
id: MMO:0000861
name: Promethion multiplexed metabolic phenotyping analysis
def: "The Promethion Metabolic /Behavioral Phenotyping System analyzes rat behaviors in real time with second-by-second data acquisition from all sensors. The system is configurable with devices for ingestive behavior studies and activity including cage movement and wheel running. The analysis is driven with SableHD™ (Sable Systems Int.) high-definition digital technology." [https://www.sablesys.com/products/promethion-core-line/]
synonym: "Promethion Core" EXACT []
is_a: MMO:0000254 ! body movement/behavior method
is_a: MMO:0000618 ! consumption measuring method
created_by: slaulede
creation_date: 2023-10-02T12:57:10Z

[Term]
id: MMO:0000862
name: single cell RNA-seq assay
def: "This is a method which combines single cell isolation and RNA-seq, which assesses transcript expression and structure via high-throughput sequencing. Sample RNA is purified, fragmented, reverse transcribed to cDNA with the addition of sequencing primers, sequenced and analyzed." [https://en.wikipedia.org/wiki/Single-cell_transcriptomics, https://rnaseq.uoregon.edu]
synonym: "scRNA-seq assay" EXACT []
synonym: "single cell ribonucleic acid sequencing assay" EXACT []
synonym: "single-cell RNA-seq" EXACT []
synonym: "single-cell RNA-seq assay" EXACT []
is_a: MMO:0000222 ! isolated cell method
is_a: MMO:0000659 ! RNA-seq assay
created_by: slaulede
creation_date: 2023-10-02T15:31:20Z

[Typedef]
id: OBO_REL:part_of
name: part_of
created_by: mshimoyama
creation_date: 2010-08-05T01:45:43Z