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Check results of Q2Solution.py #10

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dkoslicki opened this issue Mar 6, 2018 · 2 comments
Closed

Check results of Q2Solution.py #10

dkoslicki opened this issue Mar 6, 2018 · 2 comments
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@dkoslicki
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From @dkoslicki on November 26, 2017 23:9

Since I don't have any "ground truth" for these, those with more bio knowledge, please make sure they look plausible/are correct.

You can run it yourself on all Q2 drugs/diseases via:

git pull
python3 Q2Solution.py -a

Copied from original issue: dkoslicki/NCATS#107

@dkoslicki
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Example of dubious results:

python3 Q2Solution.py -r acamprosate -d Alcoholism
The possible clinical outcome pathways include: 
1. 
The drug acamprosate targets the protein P14416 which is involved with (among others) the Myogenesis pathway and associated protein P01303 which is relevant to the female gonad and alleviates symptoms of Alcoholism. (Confidence 0.421015).
<snip>

but possibly not as seen in some, research, articles?

@dkoslicki
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Closing due to it no longer being relevant.

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