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Introduction:

This document describes the TCGA-GBM data analysis performed for the manuscript titled "synNotch-programmed iPSC-derived NK cells usurp TIGIT and CD73 activities to mediate potent targeting of glioblastoma", published in journal "Nature Communications" in 2024.

Operating System:

R version 3.5.1 (2018-07-02) on Microsoft Windows 10 Education Version 10.0.19045 Build 19045

Installation

Install R through CRAN and then install packages listed above through CRAN or Bioconductor. Typical install time is ~20 minutes.

To install Bioconductor packages, do:

install.packages("BiocManager")
BiocManager::install("packageName")

To install R packages through CRAN:

install.packages("packageName")

Code availability:

Please follow this link to view the document describing the R-code to download and analyze TCG-GBM data and generate figure 1G and 1H in the manuscript.

Complete code as R Markdown file (index.Rmd) is available via this GitHub Repository.

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