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Scribing Preparations

Lecture 18: Phylogenomics: Gene/species trees, reconciliation, recombination graphs

Ethan Sherbondy & Orit Giguzinsky

6.047 Fall 2012

This material corresponds to Lecture 16 in the notes posted here: CompBio Teaching

This is Chapter 22 in the latest textbook draft.

Scoring Matrix

<tr>
  <td>Clarity</td>
  <td>4</td>
  <td>
    The chapter is poorly written. It's riddled with grammatical errors,
    and run-on sentences. Algorithm explanations in particular could do 
    with substantial reshaping to increase clarity. Often phrases are introduced,
    e.g. gene tree, and remain unexplained until much later in the chapter.
  </td>
</tr>

<tr>
  <td>Completeness</td>
  <td>4</td>
  <td>
    This chapter is currently very short. It's a little unclear why 
    this material isn't just part of Chapter 21, since it ends up 
    revisiting a lot of the same ideas (eg: paralogs v. orthologs)
    without much added depth. Sections 22.8-22.11 have yet to be 
    written.
  </td>
</tr>

<tr>
  <td>Figures</td>
  <td>5</td>
  <td>
    Figures seem to be scattered somewhat
    randomly throughout the chapter. Many of them are left unexplained,
    and others aren't explained until 2+ pages after they're displayed.
  </td>
</tr>

<tr>
  <td>Overall Quality</td>
  <td>4</td>
  <td>This chapter needs a ton of work to thoroughly and clearly
      cover the material presented. I'd like to substantially rewrite 
      and expand on the notes. The figures themselves are great, but
      most are left unexplained.
  </td>
</tr>


I plan to write the initial draft of the missing sections at the end of the chapter.
I'll also be sweeping through the existing notes to amend typos, poor wording, and run-ons.
The diagrams on page 268 need to be broken up and placed in appropriate locations throughout the
chapter. Most diagrams also demand further explanation. After correcting the existing content, I'll
probably do another sweep through to reconsider how the notes should be organized.
Category Rating Justification
Structure 6 The notes generally follow the progression of Matt's guest lecture. Coverage of the coalescent model is poor. It is currently explained in isolation as the legend for Figure 22.17. The topic deserves its own proper subsection.