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Force germline on low DOC #234

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douweschulte opened this issue Jul 3, 2023 · 0 comments
Open

Force germline on low DOC #234

douweschulte opened this issue Jul 3, 2023 · 0 comments
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A-alignment Area: Related to alignments C-enhancement Category: New feature or request M-possible-scoring-change Misc: Something that can affect the scoring M-unrefined-idea Things that are up in the air on the need of being implemented, as well as the exact implementation.

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@douweschulte
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Allow the user to specify that on low DOC positions the germline should be taken instead of the consensus sequence. This could also be a more gray definition where the germline has a specific weight attached to it and a sufficiently high scoring option still has preference, but that is left for implementation time.
@douweschulte douweschulte added C-enhancement Category: New feature or request M-possible-scoring-change Misc: Something that can affect the scoring M-unrefined-idea Things that are up in the air on the need of being implemented, as well as the exact implementation. A-alignment Area: Related to alignments labels Jul 3, 2023
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A-alignment Area: Related to alignments C-enhancement Category: New feature or request M-possible-scoring-change Misc: Something that can affect the scoring M-unrefined-idea Things that are up in the air on the need of being implemented, as well as the exact implementation.
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