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ENH/Example: GLM-QMLE parameterized link and variance functions and margins #4276

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josef-pkt opened this issue Feb 26, 2018 · 0 comments

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josef-pkt commented Feb 26, 2018

mainly adding a reference to an application that brings several parts together

also related in motivation and discussion:

bonus: They describe how to compute start_params

Basu, Anirban, and Paul J. Rathouz. 2005. “Estimating Marginal and Incremental Effects on Health Outcomes Using Flexible Link and Variance Function Models.” Biostatistics 6 (1): 93–109. https://doi.org/10.1093/biostatistics/kxh020.

two comment on their methods:

  • computational: They use Box-Cox link directly which does not enforce the domain constraints. They need additional constraints on the estimation, linpred, params, to get a non-negative or numerically valid mean response prediction. (exception in box-cox with negative linpred ?)
  • theoretical: Their standard errors for margins have an extra term for sampling variance (going from sample to population effect). AFAIK we and Stata don't use this, AFAIU, and it might be related to survey sampling inference. Our margins evaluate at sample/empirical distribution of exog and only take parameter uncertainty into account.

aside:
Manning, Basu, and Mullahy. 2005 have an article on using Generalized Gamma in GLM style analysis, I haven't looked at it, but this could be another target when implementing Generalized Gamma (with log-link) for accelerated failure time AFT model.
i.e. more (general) models for continuous, positive or non-negative response variables with or without censoring. This might be a bit like a parametric analogue of the above QMLE.

Manning, Willard G., Anirban Basu, and John Mullahy. 2005. “Generalized Modeling Approaches to Risk Adjustment of Skewed Outcomes Data.” Journal of Health Economics 24 (3): 465–88. https://doi.org/10.1016/j.jhealeco.2004.09.011.

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