The buttoncombos do not work with master system games.

[Yago2016-dog]

Hello.
Seen in the wiki:

"Does this work with an adapter for Master System games?
No idea. Please report back if you have any information."

With master system games from a flashcart neither the iGR nor the region change from the pad works. But it does work to change the region using the reset button.

Cheers.

[SukkoPera]

Updated, thanks.