Missing brand name in name resolution service

[micheldumontier]

Hi, querying the API, i don't get a suggestion for the label "Ongentys" , which is a brand/synonym for OPICAPONE https://pubchem.ncbi.nlm.nih.gov/compound/135565903

[vemonet]

Same for "Sertraline Tablets"

But "Sertraline" map to PUBCHEM.COMPOUND:68617

[cbizon]

Thanks for the report. Spot checking, I'd say we're currently pretty weak on brand names for drugs overall. The only one I found was lipitor. It doesn't seem that the sapbert that we're playing with does very well either (though it does handle the "sertraline tablets" query fine).

[gaurav]

RxNorm has a lot of brand names, so once we've added that to Babel (TranslatorSRI/Babel#150) that will hopefully mostly solve this problem.

[gaurav]

@Genomewide I remember you mentioning that you had a list of the top-selling drugs in the US for use in autocomplete checking -- I'd love to use that list to test this issue. Could you please send me that list or add it to this issue?

[gaurav]

The list of top-selling drugs @Genomewide mentioned is https://www.drugdiscoverytrends.com/50-of-2022s-best-selling-pharmaceuticals/. I'll add these to the Babel validator and report back on where we currently are with this.

[gaurav]

We support most of the top 50 best selling US drugs now. The missing ones:

• Paxlovid (CHEBI:192712)
• Spikevax (RXCUI:2601552)
• Biktarvy (RXCUI:1999667)
• Trikafta (Kaftrio, PUBCHEM.COMPOUND:165363555)
• Gardasil (RXCUI:659877)
• Prevnar (MESH:D022242)
• Botox (MESH:C542869)
• Entresto (CHEBI:9927)
• Januvia (CHEBI:40237)
• Xeplion (PUBCHEM.COMPOUND:115237)
• Symbicort (PUBCHEM.COMPOUND:5281004)

Some of that might be because we're filtering for SmallMolecule, but it's most likely either because we don't have the correct synonyms.