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Documentation Status

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VarFish

Comprehensive DNA variant analysis for diagnostics and research.

This is the repository for the web server component.

Holtgrewe, M.; Stolpe, O.; Nieminen, M.; Mundlos, S.; Knaus, A.; Kornak, U.; Seelow, D.; Segebrecht, L.; Spielmann, M.; Fischer-Zirnsak, B.; Boschann, F.; Scholl, U.; Ehmke, N.; Beule, D. VarFish: Comprehensive DNA Variant Analysis for Diagnostics and Research. Nucleic Acids Research 2020, gkaa241. https://doi.org/10.1093/nar/gkaa241.

Getting Started

VarFish Repositories

varfish-server

The VarFish Server is the web frontend used by the end users / data analysts.

varfish-annotator

The VarFish Annotator is a command line utility used for annotating VCF files and converting them to files that can be imported into VarFish Server.

varfish-cli

The VarFish Command Line Interface allows to import data through the VarFish REST API.

varfish-db-downloader

The VarFish DB Downloader is a command line tool for downloading the background database.

varfish-docker-compose

Quickly get started running a VarFish server by using Docker Compose. We provide a prebuilt data set with some already imported data.

At a Glance

  • License: MIT
  • Dependencies / Tech Stack
    • Python >=3.6
    • Django 1.11
    • PostgreSQL >=9.6

GitHub is used for public issue tracking. Currently, development happens on internal infrastructure.

VarFish Data Release Compatibility Table

VarFish DB Downloader Data Release VarFish Server
v0.2 20201006 <= v0.23