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index.Rmd
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index.Rmd
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---
title: "Home"
site: workflowr::wflow_site
output:
workflowr::wflow_html:
toc: true
---
## Overview
This is my online notebook to document and share the full results
of genome-wide enrichment analyses described in the manuscript:
> Xiang Zhu and Matthew Stephens (2017). A large-scale genome-wide enrichment analysis identifies new trait-associated genes, pathways and tissues across 31 human phenotypes. *bioRxiv.* [https://doi.org/10.1101/160770](https://doi.org/10.1101/160770).
The software that was used to generate these results is available at
https://github.com/stephenslab/rss/tree/master/src_vb.
Here is an [example](http://stephenslab.github.io/rss/Example-5)
illustrating how to use this software in enrichment analyses of GWAS summary statistics.
If you find results shown in this notebook and/or
methods implemented in the software useful for your work,
please cite the manuscript listed above,
[Zhu and Stephens (2017)](https://doi.org/10.1101/160770).
If you have any question about this notebook or the software, please feel free to contact me:
[Xiang Zhu](https://github.com/xiangzhu), `xiangzhu@uchicago.edu` or `xiangzhu@stanford.edu`.
## Results
#### Anthropometric phenotypes
- [Adult human height (Wood et al. 2014)](height_2014.html)
- [Body mass index (Locke et al. 2015)](bmi_2015.html)
- [Waist-to-hip ratio (Shungin et al. 2015)](waist_2015.html)
#### Immune-related phenotypes
- [Rheumatoid arthritis (Okada et al. 2014)][ra_2014.html]
- [Inflammatory bowel disease (Liu et al. 2015)](ibd_2015.html)
#### Metabolic phenotypes
- [Type 2 diabetes (Morris et al. 2012)](t2d_2012.html)
- [Coronary artery disease (Nikpay et al. 2015)](cad_2015.html)
#### Neurological phenotypes
- [Alzheimer's disease (Lambert et al. 2013)](load_2013.html)
- [Schizophrenia (Ripke et al. 2014)](scz_2014.html)
- [Neuroticism (Okbay et al. 2016)](neu_2016.html)
## Resources
#### dd
#### dd