Load in other format instead of matrix (i.e. Seurat objects)

[nicodemus88]

Hi developers,

I stumbled upon your paper and am very interested in using it. I am currently performing scRNA-seq on PBMCs and am very aware of the problems you described in your pre-print on annotating fine subtypes of immune cells. I find your program very interesting and would like to explore it on my dataset.

Is there any way we can input different file formats instead of standard dense matrix files? I have more than 50k cells in my dataset and we processed it with Seurat. Converting it to a matrix will result it in a very huge matrix file. Is there any way we can overcome this issue?

Thank you. Hoping to hear back soon...

[xliu-uth]

Hi nicodemus88,

Thank you for letting us know the issue! I am looking into this to see whether Seurat or data.table could be used. Will come back to you soon.

Best,
Xuan

[nicodemus88]

Hi Xuan,

Thank you for your feedback. I'll look forward to your update!