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RiboCode nf-core module #58

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JackCurragh opened this issue Oct 20, 2023 · 0 comments
Open

RiboCode nf-core module #58

JackCurragh opened this issue Oct 20, 2023 · 0 comments

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@JackCurragh
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Hi Developers!

I am one of the developers of the nf-core/riboseq pipeline that we have started work on recently. It is now recognised as 'in-development" by the nf-core community but we still have a lot of work to do. I am trying to develop a RiboCode module so that the pipeline can support ORF calling as an option.

Firstly, I wanted to let you know about this effort and secondly, I have a few suggestions regarding the usability of the tool.

  1. GTF parsing - this could be made to work on a wider range of GTF variants. Much of this can be handled by the GTFupdate subtool. eg GTFupdate should sort the gtf file
  2. Switch to pyfaidx - Brent Pedersen the developer of pyfasta archived it back in 2018. This should not be too arduous but unfortunately it is not a straight swap.

I am happy to help with these and will likely make PRs here for them as I need them

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