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Applications and validation analyses shown in the manuscript

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Results

Applications and validation analyses shown in the manuscript

Networks

The two network files used in the case scenario.

Validation

To validate the disease-drug pairs prioritized by Drug2ways, we used clinical trial information (i.e., drugs that have been tested on a given indication) from ClinicalTrials.gov mapped to each of the networks.

Citation

If you use drug2ways for your research please cite our paper:

Daniel Rivas-Barragan, Sarah Mubeen, Francesc Guim-Bernat,Martin Hofmann-Apitius, and Daniel Domingo-Fernández (2020). Drug2ways: Reasoning over causal paths in biological networks for drug discovery. PLOS Computational Biology 16(12): e1008464; https://doi.org/10.1371/journal.pcbi.1008464

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