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Covid-19 Local Information Comparison web application (CLIC Brazil)

This repository contains the the source code for the batch processes run on a daily basis to update the data in the CLIC Brazil app (https://cmmid.github.io/visualisations/lacpt) and to carry out analyses to identify factors associated with the time to arrival and initial intensity of the COVID-19 epidemic in different municipalities

There are two sets of scripts included in the repository .

Set 1) Are the scripts required for downloading the source COVID-19 case and deaths data and processing it to produce the outputs presented in the app

CLIC_Brazil_Script_directories.R - This is used to hardcode the directory paths and will need to be edited to reflect your local environment, You will need to edit the reference to this which is the header for each R script

CLIC_Brazil_Data_update_batch.R - This calls the 6 scripts used in the data processing and analysis pipeline. It can be run interactively or via a bash script or similar

CLIC_Brazil_Dataload.R - Used to download the data from the brazil.IO repository and format it for later steps in the pipeline

CLIC_Brazil_Data_cleaning.R - Used for data cleaning to ensure consistency of place names etc. from the various data sources

CLIC_Brazil_standardisation_implementation.R - Carries out the 3rd administrative level (municipality) age/population standardisation to allow meaningful comparisons to be made between places

CLIC_Brazil_standardisation_functions.R - Functions called by the standardisation script and other scripts

CLIC_Brazil_calculate_Rt_Estimates.R - Script which uses the Epifilter package to calculate Rt estimates for each municipality

CLIC_Brazil_peak_prediction.R - Analytical routine which predicts for each municipality the probability that a new peak incidence will be reached in the next 30 days based on preceding incidence data

Set 2) Are analytical scripts which use the data derived in the daily batch process

CLIC_Brazil_multivar_functions.R - Functions written to automate some steps in the development of tabular outputs from univariable and multivariable linear regression analyses

CLIC_Brazil_regression_data_prep.R - Script to prepare data required in the Tobit regression and Rt regression analyses - this must be run prior to these scripts

CLIC_Brazil_threshold_Tobit_analysis.R - Script to carry out Tobit regression analyses to identify factors associated with the time taken for the COVID-19 epidemic to become established in a particular municipality from the date it was first identified in Brazil

CLIC_Brazil_Rt_regression_analysis.R - Script to carry out linear regression analyses to identify factors associated with intensity of the initial epidemic - assesses as the Mean Rt over a fixed time window

**The following directories contain source data required by the scripts **

case_age_dist - age/case distribution data for COVID 19 from the ealry stages of the epidemic

pop_age_dist - distributions of age/population for each municipality

epifilter - sub-directory of scripts for the epifilter package

ibge - data on the socio-demogrpahic characteristics of municipalities across Brazil drawn from the 2010 census

interventions - data on interventions collate by the CEPALobservatory and edited by Andreza de Souza Santos ( (http://www.nature.com/articles/s41597-021-00859-1 https://www.cnm.org.br/biblioteca/exibe/14729 )

municipalities - reference data on municipalities and micro regions within Brazil

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repository of files and data for the CLIC brazil app and analyses

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