AGECalibrator

This is the source code for the AGECalibrator app

The files:

• functions.R contains the necessary functions.
• main.R runs the Shiny app
• ui.R and server.R contain the code for the user interface and server, respectively.

The data folder contains test data, which you can use to test your installation. The docs folder contains the manual.

Local installation

Dependencies

• R => 3.6.0
• shiny
• sninydashboard
• DT
• ggplot2
• dplyr
• tidyr
• remotes
• rPeaks
• Rcpp
• coin
• multcomp

Installation

The following installation instructions are provided for the case if you (for any reason) prefer to run the app locally.

Open the main.R file in RStudio and run it to install the necessary packages. Then press the Run button to run the app.

The installation was tested in Linux-based systems only but should be platform independent (provided that you know how to install all necessary packages).

Citation

If you find AGECalibrator useful, please consider citing the manuscript describing it:

Drozdova PB, Barbitoff YA, Belousov MV, Skitchenko RK, Rogoza TM, Leclercq JY, Kajava AV, Matveenko AG, Zhouravleva GA, Bondarev SA. Estimation of amyloid aggregate sizes with semi-denaturing detergent agarose gel electrophoresis and its limitations. Prion. 2020;14(1):118-28. https://dx.doi.org/10.1080/19336896.2020.1751574