My name is Diana Lin, and I’m a research programmer and data scientist at the Genome Sciences Centre at BC Cancer in the Dr. Aly Karsan Lab. Currently, I am developing bioinformatics pipelines for next-generation sequencing data.
I recently graduateed from the Bioinformatics Graduate program at the University of British Columbia (UBC) in Vancouver, BC. In October 2021, I finished my Master of Science in Bioinformatics. In 2018, I completed my Bachelor of Science in Physiology at McGill University. In between, I held an 8-month internship at the Bioinformatics Technology Lab.
Learn more about me here.
Lin, D. (2021). High throughput in silico discovery of antimicrobial peptides in amphibian and insect transcriptomes. University of British Columbia. https://dx.doi.org/10.14288/1.0402476
Lin, D., Sutherland, D., Aninta, S.I., Louie, N., Nip, K.M., Li, C., Yanai, A., Coombe, L., Warren, R.L., Helbing, C.C., Hoang, L.M.N., Birol, I. (2022). rAMPage: Rapid Antimicrobial Peptide Annotation and Gene Estimation. Canada’s Michael Smith Genome Sciences Centre at BC Cancer. https://github.com/bcgsc/rAMPage
Richter, A., Sutherland, D., Ebrahimikondori, H., Babock, A., Louie, N., Li, C., Coombe, L., Lin, D., Warren, R.L., Yanai, A., Kotkoff, M., Helbing, C.C., Hof, F., Hoang, L.M.N., Birol, I. (2022). Associating Biological Activity and Predicted Structure of Antimicrobial Peptides from Amphibians and Insects. Antibiotics 11(12). https://doi.org/10.3390/antibiotics11121710
Lin, D., Sutherland, D., Aninta, S.I., Louie, N., Nip, K.M., Li, C., Yanai, A., Coombe, L., Warren, R.L., Helbing, C.C., Hoang, L.M.N., Birol, I. (2022). Mining Amphibian and Insect Transcriptomes for Antimicrobial Peptide Sequences with rAMPage. Antibiotics 11(7). doi: https://doi.org/10.3390/antibiotics11070952
Gagalova, K. K., Whitehill, J. G. A., Culibrk, L., Lin, D., Levesque-Tremblay, V., Keeling, C. I., Coombe, L., Birol, I., Bohlmann, J., Jones, S. J. M. (2022). The genome of the forest insect pest Pissodes strobi reveals genome expansion and evidence of a Wolbachia endosymbiont. G3 Genes|Genomes|Genetics, jkac038. doi: https://doi.org/10.1093/g3journal/jkac038
Lo T, Coombe L, Lin D, Warren RL, Kirk H, Pandoh P, Zhao Y, Moore RA, Mungall AJ, Ritland C, Bousquet J, Jones SJM, Bohlmann J, Thomson A, Birol I. 2020. Complete Chloroplast Genome Sequence of a Black Spruce (Picea mariana) from Eastern Canada. Microbiol Resour Announc 9:e00877-20. doi: 10.1128/MRA.00877-20.
Lin D, Coombe L, Jackman SD, Gagalova KK, Warren RL, Hammond SA, Kirk H, Pandoh P, Zhao Y, Moore RA, Mungall AJ, Ritland C, Jaquish B, Isabel N, Bousquet J, Jones SJM, Bohlmann J, Birol I. 2019. Complete chloroplast genome sequence of a white spruce (Picea glauca, genotype WS77111) from eastern Canada. Microbiol Resour Announc 8:e00381-19. doi: 10.1128/MRA.00381-19.
Lin D, Coombe L, Jackman SD, Gagalova KK, Warren RL, Hammond SA, McDonald H, Kirk H, Pandoh P, Zhao Y, Moore RA, Mungall AJ, Ritland C, Doerksen T, Jaquish B, Bousquet J, Jones SJM, Bohlmann J, Birol I. 2019. Complete chloroplast genome sequence of an Engelmann spruce (Picea engelmannii, genotype Se404-851) from western Canada. Microbiol Resour Announc 8:e00382-19. doi: 10.1128/MRA.00382-19.
Master of Science, Bioinformatics, University of British Columbia, 2021
Bachelor of Science, Physiology, McGill University, 2018
| Presentation | Date |
|---|---|
| Karsan Lab Interview | Feb 10, 2022 |
| MSc Thesis: Defence | Sep 29, 2021 |
| Poster: ISMB | Jul 25, 2021 |
| GSC Bioinformatics Weekly Seminar - Exit Seminar: Discovering antimicrobial peptides in amphibian and insect transcriptomes | Jul 16, 2021 |
| MSc Thesis: Committee Meeting #2 | May 20, 2021 |
| Poster: BIGX | Mar 30, 2021 |
| Poster: BC Cancer Research Day | Sep 21, 2020 |
| GSC Bioinformatics Weekly Seminar: Mining Amphibian and Insect Transcriptomes for Antimicrobial Peptides | Jul 03, 2020 |
| MSc Thesis: Committee Meeting #1 | Jun 15, 2020 |
| STAT 540: Differential Methylation in Primary vs Metastatic Cancer | Apr 26, 2020 |
| MEDG 505: Genome Skimming | Mar 13, 2020 |
| Genome BC Geneskool Workshop: Alien Babies | Feb 18, 2020 |
| MEDG 505: Is junk DNA bunk? A critique of ENCODE | Jan 24, 2020 |
| Genome BC Geneskool Workshop: Who Killed Kyle? | Dec 02, 2019 |
| RLadies Vancouver Workshop: Data Visualization Lessons from Hackseq | Nov 18, 2019 |
| BIOF 501: PastML: A Fast Likelihood Method to Reconstruct and Visualize Ancestral Scenarios | Oct 31, 2019 |
| BIOF 501: Single cell technologies in sequence assembly and genome construction | Oct 03, 2019 |
| BIOF 501: Unicycler: Resolving bacterial genome assemblies from short and long sequencing reads | Sep 12, 2019 |
| PHGY 516: Genetic and Functional Drivers of Diffuse Large B Cell Lymphoma | Mar 19, 2018 |
| PHGY 550: MC4R-dependent suppression of appetite by bone-derived lipocalin 2 | Nov 20, 2017 |
| PHGY 488: Differentiation of pluripotent stem cells to muscle fiber to model Duchenne muscular dystrophy | Nov 01, 2017 |
| PHGY 550: Acquired hypocalciuric hypercalcemia due to autoantibodies against the calcium-sensing receptor | Oct 23, 2017 |
| PHGY 312: The Cardiac Na Channel | Mar 10, 2017 |
| Paper | Date |
|---|---|
| MEDG 505: Wikipedia Article: Genome skimming | Mar 13, 2020 |
| Microbiology Resource Announcements: Complete chloroplast genome sequence of an Engelmann spruce (Picea engelmannii, genotype Se404-851) from western Canada | Jun 13, 2019 |
| Microbiology Resource Announcements: Complete chloroplast genome sequence of a white spruce (Picea glauca, genotype WS77111) from eastern Canada | Jun 06, 2019 |
| PHGY 488: The physiological role of deubiquitinase A20 in inflammation and related diseases | Apr 05, 2018 |
| PHGY 550: In vivo deactivation of the Wnt signalling pathway in Hyp mice, a mouse model for X-linked hypophosphatemia | Dec 07, 2017 |
| PHGY 488: Differentiation of pluripotent stem cells to muscle fiber to model Duchenne muscular dystrophy | Nov 01, 2017 |
| PHGY 550: In vivo effects of the knocknout of Lyz2 on the process of osteoclast differentiation in mice | Oct 03, 2017 |
| PHGY 313: Case Study #6: X-linked Sideroblastic Anemia | Apr 03, 2017 |
| PHGY 314: The Inferotemporal Cortex | Nov 24, 2016 |
| PHGY 311: A Critique of "A Gain-of-Function Mutation in Nav1.6 in a Case of Trigeminal Neuralgia" | Nov 13, 2016 |
- Picea glauca (genotype WS77111) chloroplast genome
- Repository
- Genbank sequence MK174379
- Publication
- Picea engelmannii (genotype Se404-851) chloroplast genome
- Repository
- Genbank sequence MK241981
- Publication
- BIOF501: Special Topics in Bioinformatics
- BIOF520: Problem-Based Learning in Bioinformatics
- MEDG505: Genome Analysis
- MICB405: Bioinformatics
- STAT540: Statistical Methods for High Dimensional Biology
- STAT545: Exploratory Data Analysis
- STAT547: Topics in Statistics
- COMP 202: Introduction to Programming
- COMP 206: Introduction to Software Systems
- COMP 250: Introduction to Computer Science
- COMP 322: Introduction to C++
- COMP 364: Computer Tools for Life Sciences
- PHGY 311: Channels, Synapses & Hormones
- PHGY 312: Respiratory, Renal, & Cardiovascular
- PHGY 313: Blood, Gastrointestinal, & Immune Systems Physiology
- PHGY 314: Integrative Neuroscience
- PHGY 488: Stem Cell Biology
- PHGY 516: Physiology of Blood 2
- PHGY 550: Molecular Physiology of Bone