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CoRegFlux aims is to provides tools to integrate reverse engineered GRN and gene-expression into metabolic models to improve prediction of phenotypes, both for metabolic engineering, through transcription factor or gene (TF) knock-out or overexpression in various conditions, and to improve our understanding of the cells inner-working.

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CoRegFlux requires the installation of glpkAPI, a CRAN package (R Interface to C API of GLPK), which needs GLPK Version >= 4.42. 
In case GLPK is not already install on the computer, the user will need to download it from https://www.gnu.org/software/glpk/#downloading before proceeding to CoRegFlux installation.

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CoRegFlux aims is to provides tools to integrate reverse engineered GRN and gene-expression into metabolic models to improve prediction of phenotypes, both for metabolic engineering, through transcription factor or gene (TF) knock-out or overexpression in various conditions, and to improve our understanding of the cells inner-working.

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