This folder contains ipython notebook files FVLmod_VariantsFiltration.ipynb and FVLmod_Simulation.ipynb that give an overview of the whole exome sequencing analysis and permutations for variant distribution done for the following manuscript:

"Whole exome sequencing of ENU-induced thrombosis modifier mutations in the mouse"

Kärt Tomberg, Randal J. Westrick,Emilee N. Kotnik, David Siemieniak, Guojing Zhu, Thomas Saunders, Audrey C. Cleuren, and David Ginsburg

It contains:

• Information about raw fastq file location
• Overview of the alignment, variant calling and annotation
• All in-house developed scripts for variant filtering
• Scripts used for permutations of variant distribution