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Langevin equations for landmark image registration with uncertainty

This Python code accompanies the paper Langevin equations for landmark image registration with uncertainty, S. Marsland and T. Shardlow (2016).

Registration of images parameterised by landmarks provides a useful method of 
describing shape variations by computing the minimum-energy time-dependent deformation
field that flows one landmark set to the other. This is sometimes known as the geodesic
interpolating spline and can be solved via a Hamiltonian boundary-value problem to give
a diffeomorphic registration between images. However, small changes in the positions of
the landmarks can produce large changes in the resulting diffeomorphism. We formulate
a Langevin equation for looking at small random perturbations of this registration. The
Langevin equation and three computationally convenient approximations are introduced
and used as prior distributions. A Bayesian framework is then used to compute a posterior
distribution for the registration, and also to formulate an average of multiple sets of
landmarks.

Example sets and further explanation about the code are found in the supplement.

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