v2.1
This release adds functionality for optionally identifying variable-width "peaks" within hotspots, the latter of which may occasionally be statistically significant across a somewhat wide stretch of contiguous bp (e.g. ~2kb). These variable-width peaks can be supplied as input to our software for building an "index" or "master list" of DHSs from a collection of samples (github Altius/Index). This release also contains a fix for an "underflow" issue in FDR reporting, as well as other minor improvements.
Please be sure to build all hotspot2 binaries from this release before running hotspot2. Note that two new programs have been added to report variable-width peaks: findVarWidthPeaks
and resolveOverlapsInSummit-CenteredPeaks
.