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Basic working version
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swaroopgj committed Aug 2, 2016
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115 changes: 115 additions & 0 deletions run.py
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#!/usr/bin/env python
import argparse
import os
import subprocess
import nibabel
import numpy
from glob import glob
from mvpa2.suite import *

parser = argparse.ArgumentParser(description='Example BIDS App entrypoint script.')
parser.add_argument('bids_dir', help='The directory with the input dataset '
'formatted according to the BIDS standard.')
parser.add_argument('output_dir', help='The directory where the output files '
'should be stored. If you are running group level analysis '
'this folder should be prepopulated with the results of the'
'participant level analysis.')
parser.add_argument('analysis_level',
help='Level of the analysis that will be performed. '
'Multiple participant level analyses can be run independently '
'(in parallel) using the same output_dir.',
choices=['participant', 'group'])
parser.add_argument('--participant_label',
help='The label(s) of the participant(s) that should be analyzed. The label '
'corresponds to sub-<participant_label> from the BIDS spec '
'(so it does not include "sub-"). If this parameter is not '
'provided all subjects should be analyzed. Multiple '
'participants can be specified with a space separated list.',
nargs="+")
parser.add_argument('--task',
help='Task from which the data is used for deriving hyperalignment '
'parameters')
parser.add_argument('--run',
help='Run or runs to be used for deriving hyperalignment parameters')

args = parser.parse_args()

subjects_to_analyze = []
# only for a subset of subjects
if args.participant_label:
subjects_to_analyze = args.participant_label
# for all subjects
else:
subject_dirs = glob(os.path.join(args.bids_dir, "sub-*"))
subjects_to_analyze = [subject_dir.split("-")[-1] for subject_dir in subject_dirs]

# running participant level
"""
At the participant level, load nifti data using mask and store it as hdf5 file.
This can be adapted to compute connectomes later.
"""


def prepare_subject_for_hyperalignment(subject_label, bold_fname, mask_fname, out_dir):
print('Loading data %s with mask %s' % (bold_fname, mask_fname))
ds = fmri_dataset(samples=bold_fname, mask=mask_fname)
zscore(ds, chunks_attr=None)
out_fname = os.path.join(out_dir, 'sub-%s_data.hdf5' % subject_label)
print('Saving to %s' % out_fname)
h5save(out_fname, ds)


def run_hyperalignment(subjects_to_analyze, out_dir):
# Load subject data
ds_all = []
for subject_label in subjects_to_analyze:
ds_all.append(h5load('%s/sub-%s_data.hdf5' % (out_dir, subject_label)))
# Initialize searchlight hyperalignment
slhyper = SearchlightHyperalignment(radius=2, nblocks=10, sparse_radius=5,
dtype='float16')
hmappers = slhyper(ds_all)
return hmappers


"""
Helper functions to save and load mappers
"""


def save_mappers(hmappers, fname):
h5save(fname, hmappers)


def load_mappers(fname):
return h5load(fname)

if args.analysis_level == "participant":
# sub-01_task-mixedgamblestask_run-02_bold_hmc_mni.nii.gz
prefixes = []
task_prefix = 'task-%s' % args.task
prefixes.append(task_prefix)
run_prefix = 'run-%s' % args.run
prefixes.append(run_prefix)
# XXX TODO Expose this option outside?
preproc_prefix = 'bold_hmc_mni'
prefixes.append(preproc_prefix)
# find all T1s and skullstrip them
prefix = '_'.join(prefixes)
for subject_label in subjects_to_analyze:
bold_fname = 'sub-%s_%s'%(subject_label, prefix)
bold_fname = os.path.join(args.bids_dir, "sub-%s" % subject_label,
"func", bold_fname)
mask_fname = '%s_bmask.nii.gz' % bold_fname
bold_fname = '%s.nii.gz' % bold_fname
prepare_subject_for_hyperalignment(subject_label, bold_fname, mask_fname,
args.output_dir)

# running group level
elif args.analysis_level == "group":
"""
Load data (timeseries or connectomes) stored in first-level
and run hyperalignment. Spit out mappers.
"""
hmappers = run_hyperalignment(subjects_to_analyze, out_dir=args.output_dir)
hmappers_fname = os.path.join(args.output_dir, 'hmappers.hdf5')
save_mappers(hmappers=hmappers, fname=hmappers_fname)

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