CLoSES-RT

Closed-Loop system for Electrical Stimulation in humans in Real Time

This project implements a real time closed-loop stimulation platform and GUI It is based on Simulink Real Time

Step by Step to RUN and Compile CLoSES-RT

************ To RUN using GUI ************

1. Start MATLAB2016b Make sure to have all required toolboxes (e.g.: Simulink real-Time)

2. To RUN GUI: GUIClosedLoopConsole('PatientName','patientTEST')

Step by Step to RUN and Compile Decider Models

************ To RUN using GUI ************

1. Start MATLAB (tested version is MATLAB2016b) Make sure to have all required toolboxes (Simulink real-Time, optimization toolbox)

2. Edit patient name and run script: runClosedLoopPhysiology.m

or 2. add ClosedLoopStimulation to path and To RUN GUI: GUIClosedLoopConsole('PatientName','patientTEST')

************ To COMPILE ( Simulink Real-Time Compiler ) ************

1. Run initializationScript Example to Compile: initializationScript('SIMULATION', [], 'THETA','SMOOTHBANDPOWER','REALTIME','CONTINUOUS','REFERENTIAL')

2. Open Simulink Model

3. Press BUILD button

NOTE: if building ClosedLoopStimXpcTarget on your computer you would get an error of "could not find target" - that is the expected behavior

************ Models ************ Important Models:

For simulation: ClosedLoopStim_SimulatedInput.slx
For BlackRock NSPs: ClosedLoopStimXpcTarget.slx

Main block for computation: Simulink/ClosedLoopControl.slx

****** Additional important Functions ******

1. Functions to create simulated data from your own EEG: script_createSimDataFromNEVfile.m from NS3 data script_createSimDataFromRealData.m from .mat MATLAB data

2. Look at: initializationScript.m to see the structure of sInputData

******* Configuration Files ******** Default Configuration files are located on folder: Configuration/Physiology

******* Test Data ******** Testing Data to play with the Simulink model located on folder: ExampleData

Have fun! Rina Zelmann