Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Release/11.0.0 #1967

Merged
merged 157 commits into from May 12, 2022
Merged

Release/11.0.0 #1967

merged 157 commits into from May 12, 2022

Conversation

jemten
Copy link
Collaborator

@jemten jemten commented Oct 13, 2021

This PR adds | fixes:

  • Updates MIP to version 11.0.0

Changelog

  • HmtNote: annotate mitochondrial variants in VCF file
  • Updating to latest and greatest versions
  • Mitochondrial deletion analysis
  • GATK Haplotypecaller has been turned off in favour of Deepvariant
  • Introduces possibility to store singularity images locally as a .sif file
  • Increased allele frequency cut off for when a variant is filtered out to 0.7

Tools

  • cyrius v1.1 -> v1.1.1
  • deepvariant 1.1.0-gpu -> 1.1.0
  • deeptrio 1.1.0-gpu -> 1.1.0
  • gatk 4.2.0.0 -> 4.2.2.0
  • glnexus v1.3.1 -> v1.4.1
  • HmtNote: 0.7.2
  • htslib: 1.10.2 -> 1.13
  • multiqc 1.10.1 -> v1.11
  • star-fusion 1.10.0 -> 1.10.1
  • vep release_103.1 -> release_104.3

References

  • gnomad: r3.0 -> r3.1.1
  • [NEW] gnomad mt: r3.1
  • clinvar: 20210415 -> 20210919

How to test:

  • Automatic and continuous test suite
  • Install and run NIST samples with RTG recipe activated

Expected outcome:

  • Installation, unit and integration test suite pass
  • Run of NIST samples completes without errors (attach screenshot)
  • No drop in sensitivity and specificity (attach screenshot)

Review:

  • Code review
  • Tests pass

This version is a:

  • MAJOR - when you make incompatible API changes. If applicable record manual test results in PR header
  • MINOR - when you add functionality in a backwards compatible manner. If applicable record manual test results in PR header
  • PATCH - when you make backwards compatible bug fixes or documentation/instructions

@jemten
Copy link
Collaborator Author

jemten commented May 12, 2022

@ramprasadn and @henrikstranneheim could you please OK the PR :)

Copy link
Collaborator

@ramprasadn ramprasadn left a comment

Choose a reason for hiding this comment

The reason will be displayed to describe this comment to others. Learn more.

LGTM 👍🏻

@jemten jemten merged commit 9758991 into master May 12, 2022
@jemten jemten deleted the release/11.0.0 branch May 12, 2022 08:04
@jemten jemten restored the release/11.0.0 branch May 12, 2022 08:55
Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

Successfully merging this pull request may close these issues.

None yet

3 participants