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RGT HINT differential --output-profiles #177

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EHowell1200 opened this issue Feb 23, 2021 · 1 comment
Open

RGT HINT differential --output-profiles #177

EHowell1200 opened this issue Feb 23, 2021 · 1 comment
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@EHowell1200
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Hey,

I noticed the --output-profiles option on HINT differential and it seemed perfect for what I was looking for. Well I ran it and the txt files produced for each motif only contain 1 row with the same data in the Lineplots folder txt files for each motif, seeming that it is just giving me the averaged score for all footprints, not for each instance as described. All 400+ motifs I have data for only contain a single row in the txt files and there is clearly more than 1 footprint instance for all these motifs. I included the command I ran below in case I am missing something. It would be nice to have the read scores for each footprint instance and the genomic coordinates so that I could specifically plot certain footprints (i.e. newly gained footprints/footprints only present in one condition for both samples)

Command:
rgt-hint differential --organism=mm10 --bc --nc 6 --mpbs-files=E9_1Runx1_fp_motif.bed,E9_Ctrl_fp_motif.bed --reads-files=E9_1Runx1.bam,E9_Ctrl.bam --conditions=E9_1Runx1,E9_Ctrl --output-location=E9_1Runx1_Ctrl_diff --output-profiles

@lzj1769
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lzj1769 commented Feb 25, 2021

Hi,

Thanks for reporting this issue.
I will try to fix it.

best,
Li

@lzj1769 lzj1769 self-assigned this Feb 25, 2021
@lzj1769 lzj1769 added the bug label Feb 25, 2021
@fabio-t fabio-t added this to TODO in HINT via automation Mar 1, 2021
@fabio-t fabio-t added this to the 0.13.1 milestone Mar 1, 2021
@fabio-t fabio-t modified the milestones: 0.13.1, 0.14.0 May 9, 2021
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