Datasets associated with our study of m6A modified adenoviral mRNAs
Description of files
- The .zip files each contain three text files containing output from the m6A analysis of dRNA-Seq datasets.
M3P1-M3KO1.m6A.botstrand.complete.txt -- output file from analysis of dRNA-Seq reads that align against the bottom strand of the Ad5 genome
M3P1-M3KO1.m6A.topstrand.complete.txt -- output file from analysis of dRNA-Seq reads that align against the top strand of the Ad5 genome
M3P1-M3KO1.m6A.transcripts.complete.txt -- output file from analysis of dRNA-Seq reads that align against Ad5 encoded polyadenylated RNAs
Note that the context of the comparison is described in the filename. e.g. the comparison between Ad5-infected A549 cells (parent) biorep #1 and Ad5-infected A549 cells (METTL3 k.o.) biorep #1 is described as M3P1-M3KO1
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The .bedgraph files are generated in a stranded manner from dRNA-Seq datasets aligned against the Ad5 genome (i.e. one file per strand) with 'forward' denoting the top strand and 'reverse' denoting the bottom strand
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The meRIP_adenovirus_bedgraphs.zip file contains bedgraph files generated from aligning (Illumina short-read) meRIP-Seq data against the Ad5 adenovirus genome. Three biological replicates for each condition (input / meRIP) are included for virus-infected and mock-infected samples.