Computational Biology Laboratory, Danish Cancer Society Research Center, Strandboulevarden 49, 2100, Copenhagen, Denmark

Repository associated to the publication:

Brix DM, Tvingsholm SA, Hansen MB, Clemmensen KB, Ohman T, Siino V, Lambrughi M, Hansen K, Puustinen P, Gromova I, James P, Papaleo E, Varjosalo M, Moreira J, Jäättelä M, Kallunki T. Release of transcriptional repression via ErbB2-induced, SUMO-directed phosphorylation of myeloid zinc finger-1 serine 27 activates lysosome redistribution and invasion. Oncogene. 2019 Jan 8. doi: 10.1038/s41388-018-0653-x. PubMed PMID: 30622337.

reference person for the repository: Elena Papaleo, elenap@cancer.dk

This repository contains the input data for the modelling and simulations, the outputs from analyses and the associated scripts to reproduce our data.

The three main folders in the repository contain:

-md: templates, input files, analysis files for md preparation and productive runs

-models: starting structures for the simulations

NB. .xtc trajectories file are too big to be shared in this repository but they are available upon request.