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Integration of pharmacological and drop-out CRISPR-Cas9 screens

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Integration of drug sensitivity and gene essentiality screens inform on drug mode-of-action

Description

This module contains all the Python scripts and results of the analysis. ipython notebooks are provided in the notebooks directory along with all the generated plots from the analysis.

Install dependencies and clone code repository

pip install cy

pip install xlrd

pip install jupyter

git clone https://github.com/EmanuelGoncalves/dtrace.git

Get data from figshare and unzip into dtrace/dtrace/data/ folder.

Install module and initiate jupyter notebooks

python3 setup.py sdist bdist_wheel

pip install -U dist/dtrace-0.5.0-py3-none-any.whl

jupyter notebook

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Integration of pharmacological and drop-out CRISPR-Cas9 screens

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