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NTRs for DO dependencies #182

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laurenechan opened this issue May 5, 2021 · 3 comments
Open

NTRs for DO dependencies #182

laurenechan opened this issue May 5, 2021 · 3 comments

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@laurenechan
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laurenechan commented May 5, 2021

Per requests from DO, some new disease related exposures are required across multiple patterns:

<style> </style>
Exposure Stressor Recommended xref term Full URI Other xref options
cat dander [Felis catus Dander] NCIT:C84494 http://purl.obolibrary.org/obo/NCIT_C84494 DRON:00019407
cockroaches OMIT:0004368 http://purl.obolibrary.org/obo/OMIT_0004368 NCBITaxon:85823
dog dander OMIT:0028282 http://purl.obolibrary.org/obo/OMIT_0028282  
dust mite DRON:00020118 http://purl.obolibrary.org/obo/DRON_00020118  
mold NCIT:C28266 http://purl.obolibrary.org/obo/NCIT_C28266  
mouse feces NCIT:C26415 http://purl.obolibrary.org/obo/NCIT_C26415  
pollen FOODON:03420279 http://purl.obolibrary.org/obo/FOODON_03420279 OMIT:0012028, NCIT:C79660, BTO:0001097, PO:0025281
microorganism NCIT:C14329 http://purl.obolibrary.org/obo/NCIT_C14329  
plasma product NCIT:C133266 http://purl.obolibrary.org/obo/NCIT_C133266  
platelets product NCIT:C133278 http://purl.obolibrary.org/obo/NCIT_C133278  
red blood cells product NCIT:C133280 http://purl.obolibrary.org/obo/NCIT_C133280  
foods FOBI:0001 http://purl.obolibrary.org/obo/FOBI_0001  
botulinum toxin NCIT:C163032 http://purl.obolibrary.org/obo/NCIT_C163032 FBbi:00000465
polyfluoroalkyl substance Requested at ChEBI    
perfluoroalkyl substance Requested at ChEBI    
ether glycol Requested at ChEBI    
brominated flame retardant Requested at ChEBI    
organophosphate flame retardant CHEBI:25708 http://purl.obolibrary.org/obo/CHEBI_25708  
irritant OMIT:0008624 http://purl.obolibrary.org/obo/OMIT_0008624  
secondhand smoke Requested at ENVO https://github.com/EnvironmentOntology/envo/issues/1110   
accutane NCIT:C603 http://purl.obolibrary.org/obo/NCIT_C603  
choline deficiency OMIT:0004116 http://purl.obolibrary.org/obo/OMIT_0004116  
vitamin B3 deficiency HP:0100497 http://purl.obolibrary.org/obo/HP_0100497  
poison CHEBI:64909 http://purl.obolibrary.org/obo/CHEBI_64909  
heavy metal Requested at ChEBI    
plasticizer NCIT:C55826 http://purl.obolibrary.org/obo/NCIT_C55826  
thalidomide NCIT:C870 http://purl.obolibrary.org/obo/NCIT_C870  
vitamin E acetate NCIT:C2834 http://purl.obolibrary.org/obo/NCIT_C2834  
acid rain ExO_0000013    
hurricane Requested at ENVO    
noise NCIT:C45783 http://purl.obolibrary.org/obo/NCIT_C45783  
p32 NCIT:C1698 http://purl.obolibrary.org/obo/NCIT_C1698  
strobing light Requested at ENVO    
healthcare disparity GSSO:001616 http://purl.obolibrary.org/obo/GSSO_001616  
food deprevation OMIT:0006714 http://purl.obolibrary.org/obo/OMIT_0006714  
emotional anxiety NCIT:C26696 http://purl.obolibrary.org/obo/NCIT_C26696  
peer pressure NCIT:C38452 http://purl.obolibrary.org/obo/NCIT_C38452  
stress NCIT:C35041 http://purl.obolibrary.org/obo/NCIT_C35041  
@laurenechan
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laurenechan commented May 5, 2021

  • cat dander [Felis catus Dander]
  • cockroaches
  • dog dander
  • dust mite
  • mold
  • mouse feces
  • pollen
  • microorganism
  • plasma product
  • platelets product
  • red blood cells product
  • foods
  • botulinum toxin
  • polyfluoroalkyl substance
  • perfluoroalkyl substance
  • ether glycol
  • brominated flame retardant
  • organophosphate flame retardant
  • irritant
  • secondhand smoke
  • accutane
  • choline deficiency
  • vitamin B3 deficiency
  • poison
  • heavy metal
  • plasticizer
  • thalidomide
  • vitamin E acetate
  • acid rain
  • hurricane
  • noise
  • p32
  • strobing light
  • healthcare disparity
  • food deprivation
  • emotional anxiety
  • peer pressure
  • stress

@wdduncan
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wdduncan commented Jun 3, 2021

Looking at the above list, it seems there might be some high level groupings that are worth adding. E.g.:

  • exposure to animal dander
  • exposure to extreme weather event

Adding the higher level classes would allow others add terms under them using PRs.

@laurenechan
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Deficiency pattern: exposure to a deficiency of niacin. Do not use equivalency classes, only use subclasses here. Will get incorrect inferences otherwise. You cannot use the reasoner to classify them automatically. Can only create them and then make a subclass of relation, just do NOT use the reasoner.
We will make a branch of deficiency
Deficiency of niacin, iron etc. NO logical axioms. there is a lack set of relations that could be used? The reasoner will not do logical negation with those, just will allow you to talk about a Lack without talking about negation @wdduncan ?
Maybe don't start here, but it may become useful later. It is in PATO, https://www.ontobee.org/ontology/TO?iri=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FPATO_0002000

Just need to keep separate the deficiency of the nutrient or whatever which should be likely an HPO term, only representing the lack of exposure to the nutrient in our terms, NOT the deficiency in the human.

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