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"A unifying framework for flexible excess hazard modelling with applications in cancer epidemiology"

Alessia Eletti, Giampiero Marra, Manuela Quaresma, Rosalba Radice, and F. Javier Rubio

This repository contains two data examples of link-based additive net survival models based on the paper

Eletti, A., Marra, G., Quaresma, M., Radice, R., and Rubio, F.J. (2022). A unifying framework for flexible excess hazard modelling with applications in cancer epidemiology, Journal of the Royal Statistical Society: Series C, 71: 1044-1062. https://doi.org/10.1111/rssc.12566

[Preprint] [Supplementary Material] [Journal]

The models are fitted using the R package GJRM.

  1. The first example analyses the Simulacrum dataset (https://simulacrum.healthdatainsight.org.uk/) and focuses on differences in lung cancer survival according to different deprivation categories.

The R code and outputs for this example are also available in RPubs at:

A unifying framework for flexible excess hazard modelling with applications in cancer epidemiology: The Simulacrum

"Data for this study/project/report used artificial data from the Simulacrum, a synthetic dataset developed by Health Data Insight CiC derived from anonymous cancer data provided by the National Cancer Registration and Analysis Service, which is part of Public Health England."

  1. The second example analyses the LeukSurv dataset from the R package spBayesSurv and provides additional insight on how to model spatial components. Note, however, that we do not have access to life tables from those times based on the Townsend score so for the purpose of the example we used generic values of the population hazards based on more recent life tables.

The R code and outputs for this example are also available in RPubs at:

A unifying framework for flexible excess hazard modelling with applications in cancer epidemiology: Leukemia data

Disclaimer

The data provided here and the numerical results represent numerical illustrations of the methods proposed in "A unifying framework for flexible excess hazard modelling with applications in cancer epidemiology". These data and results should not be used to make epidemiological claims.

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Data examples of link-based additive net survival models

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