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AvP detect

Georgios Koutsovoulos edited this page Sep 29, 2022 · 8 revisions

Run AvP detect

if fastml was set to false then substitute fasttree for iqtree

avp detect -i [output_dir]/mafftgroups/ -o [output_dir] -g [output_dir]/groups.tsv -t [output_dir]/tmp/taxonomy_nexus.txt -c config.yaml
  • The following folders will be created inside output dir
    • fasttree phylogenetic results in newick format for each group
    • fasttree_nexus phylogenetic results in nexus format for each group. These are best for visualisation with the a tree viewer program like FigTree
  • The following files will be created inside output dir
    • fasttree_general_results.txt shows general results for the analyses
    • fasttree_tree_results.txt shows the result for each protein

Output files

  • fasttree_tree_results.txt is a tsv file with no header with the following format

    result alignment_file tree_file protein_name
  • The result can be one of the following

    Result Description
    HGT-NT There weren't any Ingroup proteins and thus the protein is a de facto HGT
    HGT The phylogenetic tree supports the HGT hypothesis
    NO-OT Only Ingroup proteins were present
    NO The phylogenetic tree doesn't support the HGT hypothesis
    COMPLEX The topology of the phylogenetic tree couldn't give definitive results
    UNKNOWN The proteins in the tree are of unknown origin