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MSC_paper

This repository contains raw data and analysis R codes for manuscript (in progress):

Multi-omics analysis of human mesenchymal stem cell reveals cell aging determining their immunomodulatory activity through the downregulation of PD-L1

"10X_MSC" folder contains following:

-Cellranger output files of 10X single cell MSC data
-Meta data of 12 integrated MSC samples generated by Seurat analysis 

"Raw_data_proteome_MSC" folder contains:

-Raw counts of MSC proteome data

"Perseus_analysis" folder contains following:

-Data used for integrative analysis of BM and UC MSC on tanscriptome and proteome level
-Result of 2D Perseus analysis

"code" folder contains R and python codes showing major data preprocessing and filtering steps