Error while loading shared libraries: libcrypto.so.1.0.0

[arnikz]

bcftools: error while loading shared libraries: libcrypto.so.1.0.0: cannot open shared object file: No such file or directory

samtools: error while loading shared libraries: libcrypto.so.1.0.0: cannot open shared object file: No such file or directory

bcftools (1.9, h47928c2_2, bioconda)

• curl (7.64.0, h646f8bb_2, conda-forge)
  • libcurl (7.64.0, h541490c_2, conda-forge)
    • openssl (1.1.1a, h14c3975_1000, conda-forge) -> downgrade to v1.0

samtools v1.9 (h91753b0_5, bioconda)

[praneetha92]

Hi @arnikz
I encountered this error, i thought of downgrading openssl but i found out doing so might be risky, can you please help me out. Thanks in advance.
Ubuntu :- 20.04

bcftools: error while loading shared libraries: libcrypto.so.1.0.0: cannot open shared object file: No such file or directory

conda list
Name Version Build Channel
_libgcc_mutex 0.1 conda_forge conda-forge
_openmp_mutex 4.5 1_gnu conda-forge
alsa-lib 1.2.3 h516909a_0 conda-forge
bcftools 1.9 h4da6232_0 bioconda/label/broken
bedtools 2.27.1 he941832_2 bioconda/label/cf201901
blasr 5.2p1 0 bioconda/label/cf201901
brotlipy 0.7.0 py38h8df0ef7_1001 conda-forge
bwa 0.7.17 hed695b0_7 bioconda
bzip2 1.0.8 h516909a_3 conda-forge
c-ares 1.16.1 h516909a_3 conda-forge
ca-certificates 2020.11.8 ha878542_0 conda-forge
cairo 1.16.0 h9f066cc_1006 conda-forge
certifi 2020.11.8 py38h578d9bd_0 conda-forge
cffi 1.14.3 py38h1bdcb99_1 conda-forge
chardet 3.0.4 py38h924ce5b_1008 conda-forge
conda 4.9.2 py38h578d9bd_0 conda-forge
conda-package-handling 1.7.2 py38h8df0ef7_0 conda-forge
cryptography 3.2.1 py38h7699a38_0 conda-forge
curl 7.71.1 he644dc0_8 conda-forge
cycler 0.10.0 py_2 conda-forge
decorator 4.4.2 py_0 conda-forge
falcon-kit 1.8.1 pypi_0 pypi
falcon-phase 1.2.0 pypi_0 pypi
falcon-unzip 1.3.7 pypi_0 pypi
fontconfig 2.13.1 h7e3eb15_1002 conda-forge
freetype 2.10.4 h7ca028e_0 conda-forge
future 0.18.2 py38h578d9bd_2 conda-forge
gettext 0.19.8.1 hf34092f_1004 conda-forge
giflib 5.2.1 h36c2ea0_2 conda-forge
graphite2 1.3.13 h58526e2_1001 conda-forge
harfbuzz 2.7.2 ha5b49bf_1 conda-forge
hdf5 1.12.0 nompi_h1022a3e_102 conda-forge
htslib 1.10.2 hd3b49d5_1 bioconda
icu 67.1 he1b5a44_0 conda-forge
idna 2.10 pyh9f0ad1d_0 conda-forge
jpeg 9d h36c2ea0_0 conda-forge
kiwisolver 1.3.1 py38h82cb98a_0 conda-forge
krb5 1.17.1 hfafb76e_3 conda-forge
lcms2 2.11 hcbb858e_1 conda-forge
ld_impl_linux-64 2.35.1 hed1e6ac_0 conda-forge
libblas 3.9.0 2_openblas conda-forge
libcblas 3.9.0 2_openblas conda-forge
libcurl 7.71.1 hcdd3856_8 conda-forge
libdeflate 1.6 h516909a_0 conda-forge
libedit 3.1.20191231 he28a2e2_2 conda-forge
libev 4.33 h516909a_1 conda-forge
libffi 3.2.1 he1b5a44_1007 conda-forge
libgcc 7.2.0 h69d50b8_2 conda-forge
libgcc-ng 9.3.0 h5dbcf3e_17 conda-forge
libgfortran-ng 9.3.0 he4bcb1c_17 conda-forge
libgfortran5 9.3.0 he4bcb1c_17 conda-forge
libglib 2.66.2 hbe7bbb4_0 conda-forge
libgomp 9.3.0 h5dbcf3e_17 conda-forge
libiconv 1.16 h516909a_0 conda-forge
liblapack 3.9.0 2_openblas conda-forge
libnghttp2 1.41.0 h8cfc5f6_2 conda-forge
libopenblas 0.3.12 pthreads_h4812303_1 conda-forge
libpng 1.6.37 h21135ba_2 conda-forge
libssh2 1.9.0 hab1572f_5 conda-forge
libstdcxx-ng 9.3.0 h2ae2ef3_17 conda-forge
libtiff 4.1.0 h4f3a223_6 conda-forge
libuuid 2.32.1 h14c3975_1000 conda-forge
libwebp-base 1.1.0 h36c2ea0_3 conda-forge
libxcb 1.13 h14c3975_1002 conda-forge
libxml2 2.9.10 h68273f3_2 conda-forge
lz4-c 1.9.2 he1b5a44_3 conda-forge
matplotlib-base 3.3.3 py38h5c7f4ab_0 conda-forge
minimap2 2.15 ha92aebf_0 bioconda/label/cf201901
mummer4 4.0.0beta2 pl526hfc679d8_3 bioconda/label/cf201901
mutmap 2.2.0 py_0 bioconda
ncurses 6.2 h58526e2_4 conda-forge
networkx 2.5 py_0 conda-forge
nim-falcon 0.0.0 0 bioconda/label/cf201901
numpy 1.19.4 py38hf0fd68c_1 conda-forge
olefile 0.46 pyh9f0ad1d_1 conda-forge
openjdk 11.0.8 hacce0ff_0 conda-forge
openssl 1.1.1h h516909a_0 conda-forge
pandas 1.1.4 py38h0ef3d22_0 conda-forge
patsy 0.5.1 py_0 conda-forge
pb-assembly 0.0.8 0 bioconda
pb-dazzler 0.0.0 h470a237_0 bioconda/label/cf201901
pb-falcon 2.2.4 py38h1bd3507_1 bioconda
pb-falcon-phase 0.1.0 h8e334b0_1 bioconda
pbgcpp 2.0.0 0 bioconda
pbmm2 1.4.0 h56fc30b_0 bioconda
pcre 8.44 he1b5a44_0 conda-forge
perl 5.26.2 h36c2ea0_1008 conda-forge
pillow 8.0.1 py38h70fbd49_0 conda-forge
pip 20.2.4 py_0 conda-forge
pixman 0.40.0 h36c2ea0_0 conda-forge
pthread-stubs 0.4 h14c3975_1001 conda-forge
pycosat 0.6.3 py38h8df0ef7_1005 conda-forge
pycparser 2.20 pyh9f0ad1d_2 conda-forge
pyopenssl 19.1.0 py_1 conda-forge
pyparsing 2.4.7 pyh9f0ad1d_0 conda-forge
pysam 0.16.0.1 py38hbdc2ae9_1 bioconda
pysocks 1.7.1 py38h924ce5b_2 conda-forge
python 3.8.6 h852b56e_0_cpython conda-forge
python-dateutil 2.8.1 py_0 conda-forge
python-edlib 1.3.8.post2 py38hed8969a_0 bioconda
python-intervaltree 3.0.2 py_0 bioconda/label/cf201901
python-msgpack 0.6.1 py38hed8969a_3 bioconda
python-sortedcontainers 2.1.0 py_0 bioconda/label/cf201901
python_abi 3.8 1_cp38 conda-forge
pytz 2020.4 pyhd8ed1ab_0 conda-forge
qtlseq 2.1.2 py_0 bioconda
racon 1.3.1 he941832_5 bioconda/label/cf201901
readline 8.0 he28a2e2_2 conda-forge
requests 2.25.0 pyhd3deb0d_0 conda-forge
ruamel_yaml 0.15.80 py38h8df0ef7_1003 conda-forge
samtools 1.10 h2e538c0_3 bioconda
scipy 1.5.3 py38hb2138dd_0 conda-forge
seaborn 0.11.0 ha770c72_1 conda-forge
seaborn-base 0.11.0 pyhd8ed1ab_1 conda-forge
setuptools 49.6.0 py38h924ce5b_2 conda-forge
six 1.15.0 pyh9f0ad1d_0 conda-forge
snpeff 5.0 0 bioconda
sqlite 3.33.0 h4cf870e_1 conda-forge
statsmodels 0.12.1 py38h0b5ebd8_1 conda-forge
tabix 0.2.6 ha92aebf_0 bioconda
tk 8.6.10 hed695b0_1 conda-forge
tornado 6.1 py38h25fe258_0 conda-forge
tqdm 4.52.0 pyhd3deb0d_0 conda-forge
trimmomatic 0.39 1 bioconda
urllib3 1.25.11 py_0 conda-forge
wheel 0.35.1 pyh9f0ad1d_0 conda-forge
xorg-fixesproto 5.0 h14c3975_1002 conda-forge
xorg-inputproto 2.3.2 h14c3975_1002 conda-forge
xorg-kbproto 1.0.7 h14c3975_1002 conda-forge
xorg-libice 1.0.10 h516909a_0 conda-forge
xorg-libsm 1.2.3 h84519dc_1000 conda-forge
xorg-libx11 1.6.12 h516909a_0 conda-forge
xorg-libxau 1.0.9 h14c3975_0 conda-forge
xorg-libxdmcp 1.1.3 h516909a_0 conda-forge
xorg-libxext 1.3.4 h516909a_0 conda-forge
xorg-libxfixes 5.0.3 h516909a_1004 conda-forge
xorg-libxi 1.7.10 h516909a_0 conda-forge
xorg-libxrender 0.9.10 h516909a_1002 conda-forge
xorg-libxtst 1.2.3 h516909a_1002 conda-forge
xorg-recordproto 1.14.2 h516909a_1002 conda-forge
xorg-renderproto 0.11.1 h14c3975_1002 conda-forge
xorg-xextproto 7.3.0 h14c3975_1002 conda-forge
xorg-xproto 7.0.31 h14c3975_1007 conda-forge
xz 5.2.5 h516909a_1 conda-forge
yaml 0.2.5 h516909a_0 conda-forge
zlib 1.2.11 h516909a_1010 conda-forge
zstd 1.4.5 h6597ccf_2 conda-forge

[arnikz]

Hi @praneetha92,

I think, you've tested an older version of sv-callers (with pinned openssl), please use the latest 1.1.2. Also, you might need to install bc on your machine (see #44).