JPSiegMetaboMetaloRNA

Raw data and Rscripts for:

"The Metabolome Weakens RNA Helix Stability and Increases RNA Chemical Stability"

Jacob P. Sieg1,2, Lauren McKinley1,2, Melanie Huot3,4, Neela H. Yennawar5, and Philip C. Bevilacqua*1,2,3

1 Department of Chemistry, Pennsylvania State University, University Park, PA 16802. 2 Center for RNA Molecular Biology, Pennsylvania State University, University Park, PA 16802. 3 Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA 16802. 4 The Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA 16802.

*Corresponding author

Cite

(1) Sieg, J. P.; McKinley, L. N.; Huot, M. J.; Yennawar, N. H.; Bevilacqua, P. C. The Metabolome Weakens RNA Thermodynamic Stability and Strengthens RNA Chemical Stability. Biochemistry 2022. https://doi.org/10.1021/acs.biochem.2c00488.

Contents

1. Drafts: Directory containing relevant versions of the manuscript
2. Figures: Directory containing raw data and final versions of each figure
3. JPSiegMetaboMetaloRNA: Rproject that can be opened in Rstudio
4. LICENSE: Terms of use for data and code
5. R: Directory containing raw scripts for making each figure
6. README.md: This document, describing what is availible here
7. Reviewer_response_figure: Figures for the response to reviewers