Srapamycinicus_metabolic_network_analysis

This work has been published

Comparative genomic analysis of Streptomyces rapamycinicus NRRL 5491 and its mutant overproducing rapamycin DOI https://doi.org/10.1038/s41598-022-14199-6

These codes are for:

Analyzing the impact of the large deletion on the metabolic level by using genome-scale metabolic network (GEM)
Comparative flux analysis to find rational explaination as to why the mutant strain can produce 4 times more rapamycin

Name		Name	Last commit message	Last commit date
Latest commit History 3 Commits
draft_model		draft_model
final_model		final_model
inputs		inputs
outputs		outputs
template_model		template_model
HP_gem_refinement.ipynb		HP_gem_refinement.ipynb
README.md		README.md
WT_gem_refinement.ipynb		WT_gem_refinement.ipynb
essential_gene_analysis.ipynb		essential_gene_analysis.ipynb
metabolic_flux_comparison.ipynb		metabolic_flux_comparison.ipynb

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