Scripts and output from "A mutational atlas for Parkin proteostasis" by Lene Clausen, Vasileios Voutsinos, Matteo Cagiada, Kristoffer E. Johansson, Martin Grønbæk-Thygesen, Snehal Nariya, Rachel L. Powell, Magnus K. N. Have, Vibe H. Østergaard, Amelie Stein, Douglas M. Fowler, Kresten Lindorff-Larsen and Rasmus Hartmann-Petersen.
Files and Directories
- abundance.csv: Abundance scores
- tile_stability.csv: Degron TSI scores for PRKN tiles
- PARKIN_SI.ipynb: Jupyter notebook with plots based on the article supplementary CSV file
- pacbio: Scropts for processing long CCS reads into a barcode map
- illumina: Scripts for calculating the abundance scores
- illumina_degron: Scripts for calculating the degron TSI scores
Pacbio and illumina sequencing reads for abundance scores are available at https://doi.org/10.17894/ucph.ef2e30c5-d262-4713-86e8-a3964b5dd6c7
Sequencing reads for degron TSI scores are available at https://doi.org/10.17894/ucph.d879cfce-efb3-4eaa-928f-87a94d9560ef
