Benchmark

GRAY

precision	channels	AviSynth	VapourSynth
int8	Y	25 fps	24 fps
int16	Y	22 fps	21 fps
half	Y		21 fps
float	Y		18 fps

YUV 4:2:0

precision	channels	AviSynth	VapourSynth
int8	Y	25 fps	23 fps
int8	UV	67 fps	58 fps
int16	Y	22 fps	20 fps
int16	UV	52 fps	52 fps

YUV 4:2:2

precision	channels	AviSynth	VapourSynth
int8	Y	25 fps	23 fps
int8	UV	33 fps	32 fps
int16	Y	22 fps	20 fps
int16	UV	29 fps	29 fps

YUV 4:4:4

precision	channels	AviSynth	VapourSynth
int8	YUV	17 fps	16 fps
int10	YUV		15 fps
int16	YUV	13 fps	12 fps
half	YUV		12 fps
single	YUV		9 fps

RGB

precision	channels	AviSynth	VapourSynth
int8	RGB	19 fps	16 fps
int10	RGB		15 fps
int16	RGB		12 fps
half	RGB		12 fps
single	RGB		9 fps

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1920x1080, KNLMeansCL(d=1, a=2, s=4, device_type="GPU"), version 1.0.2.

Tested with the following configuration: Intel Core i5 4690 (3.9GHz), 8GB DDR3-1600 MHz, AMD Radeon RX 480, Windows 10 64bit.