Up-to-date and curated list with information related to health-span extension.
As we do not have unlimited time on this planet yet, only information transmitted in an optimal form should become part of this list.
We should avoid overlapping content unless it comes in a different format (audio-only, video, writing). For example, both this article and the original research that it draws upon are helpful to understand Metformin's mechanism of action, but in this case, I would make a subjective call and only add the article to this list.
Removing/replacing items that are outdated or not optiomal anymore is as valuable as adding new ones.
Short-term objective: someone going through the information from this list should improve his understanding of aging and become able to devise an actual program to increase his health-span.
Long-term objective: As Richard Feynman would have put it, we're trying to understand aging and how to solve it "in terms of the smallest set of principles."
Articles that summarize the current state of understanding on a topic.
- The Hallmarks of Aging
- The Quest to Slow Ageing Through Drug Discovery - Some of the most promising interventions to slow ageing based on the robustness of pre/clinical trials.
- Revisiting the Hallmarks of Aging to Identify Markers of Biological Age - Putative biomarkers of aging for each of the nine hallmarks.
- DNA Methylation Clocks and Their Predictive Capacity for Aging Phenotypes and Healthspan - Comparison between DNA methylation clocks.
If a book is available in both audio and written form, add only the audiobook to this list unless it is too technical and, therefore, hard to follow. If we’re doing this right, books should be of last resort because summarized content is preferred. Many of us already have enough university textbooks to read.
If a book is available in both audio and written form, add only the audiobook to this list unless it is too technical and, therefore, hard to follow. If we’re doing this right, books should be of last resort because summarized content is preferred. Many of us already have enough university textbooks to read.
Be open-minded in this category. Example: maybe, in the future, a VR game could teach us how to act in life threatening situations.
Contributions welcome! Read the contribution guidelines first.