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Gene count normalization in imaging-based spatially resolved transcriptomics

This repository contains the code used to analyze the impact of gene panel design and choice of gene count normalization approach on downstream analysis and biological interpretation of imaging-based spatially resolved transcriptomics data.

More details can be found in the bioRxiv preprint.

Summary of data sets and analyses performed:

Study Design

Graphical representation of conclusions:

Conclusion skewed \

Conclusion nonskewed

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