morphology_mechanisms.hoc

/*~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
	Loader for a 1-compartment Purkinje cell model
	including recombinant proteins VSFP2.3 and VSFP3.1

	Laboratory for Neuronal Circuit Dynamics
	RIKEN Brain Science Institute, Wako City, Japan
	http://www.neurodynamics.brain.riken.jp

	Date of Implementation: May 2008
	Contact: akemann@brain.riken.jp

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~*/

celsius = 37  // (degC)

create soma
access soma

soma.nseg = 1
soma.L = 20		// (um)       
soma.diam = 20	// (um)
soma.cm = 1       // (uF/cm2)
soma.Ra = 150	// (ohm cm) 

soma {
insert Nav11
insert Kv1
insert Kv3
insert Kv4
insert KCa1
insert Caint
insert Cav2
insert HCN
insert leak
insert VSFP23M3
insert VSFP31M3
}

gateCurrent_Nav11 = 0
gateCurrent_Kv1 = 0
gateCurrent_Kv3 = 0
gateCurrent_Kv4 = 0
gateCurrent_KCa1 = 0
gateCurrent_Cav2 = 0
gateCurrent_HCN = 0

baseline_VSFP23M3 = 0
baseline_VSFP31M3 = 0

soma.ena = 60	// (mV)
soma.ek = -88	// (mV)
soma.eh_HCN = -30
soma.e_leak = -61
soma.cao = 2   // (mM)
     
soma.gbar_Nav11 = 0.038
soma.gbar_Kv1 = 0.011
soma.gbar_Kv3 = 0.02
soma.gbar_Kv4 = 0.0039
soma.gbar_KCa1 = 2 * 0.007
soma.pbar_Cav2 = 2 * 0.00003
soma.gbar_HCN = 2 * 0.0001
soma.gbar_leak = 0.00012

soma.nc_VSFP23M3 = 0	 // (1/cm2)
soma.nc_VSFP31M3 = 0