Stochastic model of the olfactory cilium transduction and adaptation (Antunes et al 2014)
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<html><p/> This is the readme for the model associated with the paper: <p/> Antunes G, Sebastiao AM, Simoes de Souza FM (2014) Mechanisms of regulation of olfactory transduction and adaptation in the olfactory cilium. PLoS One 9:e105531 <p/> This model was contributed by Fabio Marques Simoes de Souza. <p/> COPASI, free software, is required for this model and is available, along with documentation, from <a href="http://www.copasi.org/">http://www.copasi.org/</a> <p/> Example Usage:<br/> --------------<br/> Start COPASIUI and open model_treatment.cps. Select Time Course and click on Run. You should see a graph of Ca2+ generated:<p/> <img src="./screenshot1.png" alt="screenshot"> <p/> The figures in the paper are the mean results from hundreds of single runs. The screen shot reproduces a single run of the model. Supplementary figure S3, first column (A to E) shows the example of 5 single runs. The first column of Fig. S3 panel F shows the mean result of hundred simulations. We used the Condor Copasi platform to do it automatically: <a href="https://www.nimml.org/tools/copasi-suite/condor-copasi">https://www.nimml.org/tools/copasi-suite/condor-copasi</a> (There is a similar relationship between model_control.cps and supplementary figure 2). </html>
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