GitHub - ModelDBRepository/260967: Double cable myelinated axon (Layer 5 pyramidal neuron; Cohen et al 2020)

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Name		Name	Last commit message	Last commit date
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lib		lib
outdir		outdir
ses		ses
act-SOAX-DCPARA.type		act-SOAX-DCPARA.type
compilemod.hoc		compilemod.hoc
mosinit.hoc		mosinit.hoc
openmodel.hoc		openmodel.hoc
readme.html		readme.html
resetaxon.hoc		resetaxon.hoc
resetmode.hoc		resetmode.hoc
resetses.hoc		resetses.hoc
screenshot.png		screenshot.png

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<p>This is the readme for the model associated with the paper:
</p>
<p>Cohen CCH, Popovic MA, Klooster J, Weil M, Mobius W, Nave K, Kole MHP
(2020) Saltatory Conduction along Myelinated Axons Involves a
Periaxonal Nanocircuit. <a href="https://doi.org/10.1016/j.cell.2019.11.039">Cell</a>
</p>
<p>This NEURON code was contributed by CCH Cohen.
</p>
<p>Startup options:
</p>
<p>compilemod.hoc
</p><ul>
  <li>Compile or recompile mod files.
  </li><li>Required for running any model.
  </li><li>Run once after setup or download to a new machine.
</li></ul>
<p>openmodel.hoc
</p><ul>
  <li>View and test the model.
  </li><li>Try different parameter combinations.
  </li><li>Broadest option for model interaction.
</li></ul>
A sample screenshot of the model mid simulation:<p/>
<img src="./screenshot.png" alt="screenshot" width="600">
<p>resetmode.hoc
</p><ul>
  <li>Switch mode from passive to active and vice versa.
</li></ul>
<p>resetses.hoc
</p><ul>
  <li>Reset session data to mode-appropriate default options.
</li></ul>
<p>resetaxon.hoc
</p><ul>
  <li>Switch between model axon options. 
  </li><li>Available options include no myelin, single cable and double cable.
</li></ul>
<p><em>modeltype</em>.type
</p><ul>
  <li>Describes current model setup. Composed of three parts separated by dashes.
  </li><li>First part: active ("act") or passive ("pas").
  </li><li>Second part: selected cellular location(s) of interest combination. SO = soma, AX = axon, DE = dendrite.
  </li><li>Third part: axon model type. NOMY = no myelin, SC = single cable, DC = double cable, etc.
  </li><li>Updated after opening openmodel.hoc.
</li></ul>
<p>Usage note: To restore colour mapping if reshaping the shapeplot, select "Shape Plot" by right clicking in the plot window.</p>
  
  <p> Change April 5, 2023: Changes from Charles Cohen to lines 27, 96, and 98 of resetaxon.hoc to fix a bug first identified by Tom Morse</p>

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