GitHub - ModelDBRepository/267309: A modified Morris-Lecar model with gM and gAHP (Yang et al., 2022)

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Name		Name	Last commit message	Last commit date
Latest commit History 2 Commits
GD_gsubNa=3p3_gL=fitted_fig3-pre.mat		GD_gsubNa=3p3_gL=fitted_fig3-pre.mat
GD_gsubNa=3p5_gsubK=p7_gM=1p75_gAHP=p5_gL=2_stdev=0.1_300mdls.mat		GD_gsubNa=3p5_gsubK=p7_gM=1p75_gAHP=p5_gL=2_stdev=0.1_300mdls.mat
ML_HH_adapt.m		ML_HH_adapt.m
ML_HH_adapt_ver2.m		ML_HH_adapt_ver2.m
P_control.m		P_control.m
P_control_dg.m		P_control_dg.m
Rheo_ML_HH_JY.m		Rheo_ML_HH_JY.m
Vrest_Rinput_ML_HH.m		Vrest_Rinput_ML_HH.m
calc_EE.m		calc_EE.m
calc_fmin.m		calc_fmin.m
fast_signal_mu_40_std=10p5_length=1p5sec.mat		fast_signal_mu_40_std=10p5_length=1p5sec.mat
feedback_control.m		feedback_control.m
feedback_control_dg.m		feedback_control_dg.m
figure3E_H.m		figure3E_H.m
figure4.m		figure4.m
figure5.m		figure5.m
figure6_10.m		figure6_10.m
find_inter.m		find_inter.m
gridsearch.m		gridsearch.m
output_target_values.mat		output_target_values.mat
readme.html		readme.html
round_JY.m		round_JY.m

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<h2>Initial conductance density values:</h2>
GD_gsubNa=3p3_gL=fitted.mat - initial conductance values for Figure 4<br>
GD_gsubNa=3p5_gsubK=p7_gM=1p75_gAHP=p5_gL=2_stdev=0.1_300mdls.mat - initial conductance values for Figure 5-10<br>
 
<h2>Istim (fast fluctuating signal):</h2>
fast_signal_mu_40_std=10p5_length=1p5sec.mat - the Istim (fast fluctuating signal) used for measuring firing rate
 
<h2>Target ranges:</h2>
output_target_values.mat - target ranges for outputs— firing rate, energy efficiency, input resistance, etc.
 
<h2>Simulations:</h2>
gridsearch.m<br>
feedback_control.m   <br>
feedback_control_dg.m   <br>
P_control.m - Runs proportional feedback control without noise<br>
P_control_dg.m - Modified from P_control.m to add noise (dg)      <br>                                                                                        
ML_HH_adapt.m - Calculates V based on the input (gi’s) and returns spike timing<br>
ML_HH_adapt_ver2.m - Modified from ML_HH_adapt.m to calculate FR and energy consumption rate<br>
Rheo_ML_HH_JY.m - Modified from ML_HH_adapt.m to calculate rheobase<br>
Vrest_Rinput_ML_HH.m - Modified from ML_HH_adapt.m to calculate Vrest and input resistance<br>
calc_EE.m - Modified from ML_HH_adapt.m to calculate energy efficiency<br>
calc_fmin.m - Modified from ML_HH_adapt.m to calculate minimum frequency<br>
find_inter.m - Returns the intersection of two surfaces<br>
round_JY.m - Round to two decimal places<br>
 
<h2>Figures:</h2>
figure3E_H.m - Reproduces Figure3E-H, but can be modified to reproduce contour plots and iso-output1 contour vs. output2 plots in Figure 3A-D<br>
figure4.m - Reproduces Figure 4<br>
figure5.m - Reproduces Figure 5D, which is essentially equal to a combination of Figure 5A-C<br>
figure6-10.m - Reproduces Figure 6, but can be modified to reproduce 3D plots of iso-output surfaces, conductance trajectories and correlation matrices in Figures 7-10
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