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Squid axon (Hodgkin, Huxley 1952) (NEURON)
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The classic HH squid axon membrane model based on: Hodgkin, A.L., Huxley, A.F. (1952) A quantitative description of membrane current and its application to conduction and excitation in nerve. J. Physiol. 117: 500-544. Notes: The gif files are copies of original fig3 and fig6. Red lines are polylines drawn using idraw. The polylines have control points as near as I can place them on the circles of the data. This idraw file is then read into neuron using idraw.hoc for translating, scaling and copying into a Vector display tool. The raw data in the Vector display tools, fig3k.ses and fig6na.ses are in units of mS/cm2. These curves were rescaled to S/cm2 in the MultipleRunFitter's. The computations in the fitters differ from the original model curves of figure 3 and 6 because the original model curves are fits to the data for the specific axon 17 whereas the curves shown in these simulations are for the standard hh model. To see the simulated curves and data from a MultipleRunFitter, click on any item in the "Generators" list of the main MulRunFitter panel to pop up a generator viewer (It will be called MulRunFitter[0] Generators). Then in the main MulRunFitter panel select "Generators/Run all". Questions about the representation of this model in NEURON should be directed to Michael.Hines@yale.edu.
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Squid axon (Hodgkin, Huxley 1952) (NEURON)
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