IMPORTANT: This software is now hosted in the ConesaLab github: https://github.com/ConesaLab/MOSim
For the latest version of the software as well as issues and questions, please head to the new site.
MOSim is an R package for the simulation of multi-omic experiments that mimic regulatory mechanisms within the cell. Gene expression (RNA-seq count data) is the central data type simulated by MOSim, while the rest of available omic data types provide gene regulation information and include ATAC-seq (DNase-seq), ChIP-seq, small RNA-seq and Methyl-seq. In addition to these omics, regulation by transcription factors (TFs) can also be modeled.
MOSim is a Bioconductor R package, and we strongly recommend that it is installed from the Bioconductor repository. To install MOSim, open the R console and run:
if (!requireNamespace("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("MOSim")
The developer version can be installed from GitHub using the devtools R package:
install.packages("devtools")
devtools::install_github("ConesaLab/MOSim")
Vignettes and documentation can be accessed from MOSim's Bioconductor site, or by running the following line in the R console:
browseVignettes("MOSim")
If you used MOSim for your research, please cite:
- Martínez C, Monzó C, Conesa A, Tarazona S (2022). MOSim: Multi-Omics Simulation (MOSim). R package version 1.2.0, https://github.com/ConesaLab/MOSim.