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Impute drug_exposure_end_date using ATC Defined Daily Dose (DDD) #171

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crabcakeworld opened this issue Apr 26, 2024 · 0 comments
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@crabcakeworld
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CDM or THEMIS convention?

THEMIS

Table or Field level?

Field

Is this a general convention?

Not sure

Summary of issues

Under following situation:
1). Source data does not provide drug_exposure_end_date or any information to impute drug_exposure_end_date, e.g., days_supply etc.
2). Quantity is provided in source data.
3). Daily dose is not provided in source data

If above criteria are all satisfied, then ATC Defined Daily Dose (DDD) can be used to calculated days_supply to impute drug_exposure_end_date

Summary of answer

This has not been rectified.

days_supply = (Quantity/ATC DDD)

drug_exposure_end_date = drug_exposure_start_date + (Quantity/ATC DDD) - 1

Related links

https://forums.ohdsi.org/t/atc-ddd-to-impute-drug-exposure-end-date/12233
https://www.ohdsi.org/wp-content/uploads/2021/08/2-abstract-Medication-dosage-and-exposure-duration.pdf
https://www.ohdsi.org/wp-content/uploads/2021/08/2-poster-Medication-dosage-and-exposure-duration.pdf

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